Irving H Zucker, PhD

  • 7698 Citations
  • 51 h-Index
1973 …2020

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Research Output

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2020

An American Physiological Society cross-journal Call for Papers on “Deconstructing Organs: Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models”

Adams, J. C., Darwin Bell, P., Bodine, S. C., Brooks, H. L., Bunnett, N., Joe, B., Keehan, K. H., Kleyman, T. R., Marette, A., Morty, R. E., Ramírez, J. M., Thomsen, M. B., Yates, B. J. & Zucker, I. H., Aug 2020, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 319, 2, p. L266-L272

Research output: Contribution to journalArticle

Open Access

CORP: Assessing author compliance with data presentation guidelines for manuscript figures

Keehan, K. H., Gaffney, M. C. & Zucker, I. H., May 1 2020, In : American journal of physiology. Heart and circulatory physiology. 318, 5, p. H1051-H1058

Research output: Contribution to journalArticle

2019

Curcumin improves exercise performance of mice with coronary artery ligation-induced HFrEF: Nrf2 and antioxidant mechanisms in skeletal muscle

Wafi, A. M., Hong, J., Rudebush, T. L., Yu, L., Hackfort, B., Wang, H., Schultz, H. D., Zucker, I. H. & Gao, L., Feb 2019, In : Journal of Applied Physiology. 126, 2, p. 477-486 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Exercise training upregulates Nrf2 protein in the rostral ventrolateral medulla of mice with heart failure

Wafi, A. M., Yu, L., Gao, L. & Zucker, I. H., 2019, In : Journal of Applied Physiology. 127, 5, p. 1349-1359 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Therapeutic effects of Nrf2 activation by bardoxolone methyl in chronic heart failure

Tian, C., Gao, L., Zhang, A., Hackfort, B. T. & Zucker, I. H., 2019, In : Journal of Pharmacology and Experimental Therapeutics. 371, 3, p. 642-651 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

TRPV1 (Transient Receptor Potential Vanilloid 1) Cardiac Spinal Afferents Contribute to Hypertension in Spontaneous Hypertensive Rat

Shanks, J., De Morais, S. D. B., Gao, L., Zucker, I. H. & Wang, H. J., Oct 1 2019, In : Hypertension. 74, 4, p. 910-920 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Upregulating Nrf2 in the RVLM ameliorates sympatho-excitation in mice with chronic heart failure

Ma, A., Hong, J., Shanks, J., Rudebush, T., Yu, L., Hackfort, B. T., Wang, H., Zucker, I. H. & Gao, L., Sep 2019, In : Free Radical Biology and Medicine. 141, p. 84-92 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018
1 Scopus citations
25 Scopus citations

Sympatho-excitatory response to pulmonary chemosensitive spinal afferent activation in anesthetized, vagotomized rats

Shanks, J., Xia, Z., Lisco, S. J., Rozanski, G. J., Schultz, H. D., Zucker, I. H. & Wang, H. J., Jun 2018, In : Physiological Reports. 6, 12, e13742.

Research output: Contribution to journalArticle

4 Scopus citations
2017
3 Scopus citations

Cardiac sympathetic afferent reflex control of cardiac function in normal and chronic heart failure states

Wang, H. J., Rozanski, G. J. & Zucker, I. H., Apr 15 2017, In : Journal of Physiology. 595, 8, p. 2519-2534 16 p.

Research output: Contribution to journalArticle

16 Scopus citations
3 Scopus citations

Selective Nrf2 Gene Deletion in the Rostral Ventrolateral Medulla Evokes Hypertension and Sympathoexcitation in Mice

Gao, L., Zimmerman, M. C., Biswal, S. & Zucker, I. H., Jun 1 2017, In : Hypertension. 69, 6, p. 1198-1206 9 p.

Research output: Contribution to journalArticle

26 Scopus citations
2016

Central angiotensin-II increases blood pressure and sympathetic outflow via Rho kinase activation in conscious rabbits

Pellegrino, P. R., Schiller, A. M., Haack, K. K. V. & Zucker, I. H., Nov 1 2016, In : Hypertension. 68, 5, p. 1271-1280 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers

Mahajan, V., Gaymalov, Z., Alakhova, D., Gupta, R., Zucker, I. H. & Kabanov, A. V., Jun 1 2016, In : Data in Brief. 7, p. 1269-1282 14 p.

Research output: Contribution to journalArticle

Exercise training normalizes renal blood flow responses to acute hypoxia in experimental heart failure: Role of the α1-adrenergic receptor

Pugge, C., Mediratta, J., Marcus, N. J., Schultz, H. D., Schiller, A. M. & Zucker, I. H., Feb 1 2016, In : Journal of Applied Physiology. 120, 3, p. 334-343 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Horizontal gene transfer from macrophages to ischemic muscles upon delivery of naked DNA with Pluronic block copolymers

Mahajan, V., Gaymalov, Z., Alakhova, D., Gupta, R., Zucker, I. H. & Kabanov, A. V., Jan 2016, In : Biomaterials. 75, p. 58-70 13 p.

Research output: Contribution to journalArticle

8 Scopus citations
11 Scopus citations
3 Scopus citations

Therapeutic microRNA-based strategies in cardiovascular disease discriminate sex and age difference

Tian, C. & Zucker, I. H., Oct 15 2016, In : Journal of Physiology. 594, 20, p. 5731-5732 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Translational neurocardiology: preclinical models and cardioneural integrative aspects

Ardell, J. L., Andresen, M. C., Armour, J. A., Billman, G. E., Chen, P. S., Foreman, R. D., Herring, N., O'Leary, D. S., Sabbah, H. N., Schultz, H. D., Sunagawa, K. & Zucker, I. H., Jul 15 2016, In : Journal of Physiology. 594, 14, p. 3877-3909 33 p.

Research output: Contribution to journalArticle

45 Scopus citations
2015
11 Scopus citations

Exercise training attenuates chemoreflex-mediated reductions of renal blood flow in heart failure

Marcus, N. J., Pügge, C., Mediratta, J., Schiller, A. M., del Rio, R., Zucker, I. H. & Schultz, H. D., Jul 15 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 2, p. H259-H266

Research output: Contribution to journalArticle

12 Scopus citations
3 Scopus citations
2014
37 Scopus citations

Cardiac sympathetic afferent denervation attenuates cardiac remodeling and improves cardiovascular dysfunction in rats with heart failure

Wang, H. J., Wang, W., Cornish, K. G., Rozanski, G. J. & Zucker, I. H., 2014, In : Hypertension. 64, 4, p. 745-755 11 p.

Research output: Contribution to journalArticle

82 Scopus citations
5 Scopus citations

Simvastatin treatment attenuates increased respiratory variability and apnea/hypopnea index in rats with chronic heart failure

Haack, K. K. V., Marcus, N. J., Del Rio, R., Zucker, I. H. & Schultz, H. D., May 2014, In : Hypertension. 63, 5, p. 1041-1049 9 p.

Research output: Contribution to journalArticle

28 Scopus citations
9 Scopus citations
2013
25 Scopus citations
20 Scopus citations

Central rho kinase inhibition restores baroreflex sensitivity and angiotensin ii type 1 receptor protein imbalance in conscious rabbits with chronic heart failure

Haack, K. K. V., Gao, L., Schiller, A. M., Curry, P. L., Pellegrino, P. R. & Zucker, I. H., Mar 2013, In : Hypertension. 61, 3, p. 723-729 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

NF-κB and CREB are required for angiotensin II type 1 receptor upregulation in neurons

Haack, K. K. V., Mitra, A. K. & Zucker, I. H., Nov 11 2013, In : PloS one. 8, 11, e78695.

Research output: Contribution to journalArticle

25 Scopus citations
10 Scopus citations

Unilateral renal denervation improves autonomic balance in conscious rabbits with chronic heart failure

Schiller, A. M., Haack, K. K. V., Pellegrino, P. R., Curry, P. L. & Zucker, I. H., Oct 15 2013, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 305, 8, p. R886-R892

Research output: Contribution to journalArticle

27 Scopus citations
2012

Abnormal baroreflex function is dissociated from central angiotensin II receptor expression in chronic heart failure

Fahim, M., Gao, L., Mousa, T. M., Liu, D., Cornish, K. G. & Zucker, I. H., Mar 2012, In : Shock. 37, 3, p. 319-324 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
23 Scopus citations

Muscle reflex in heart failure: The role of exercise training

Wang, H. J., Zucker, I. H. & Wang, W., 2012, In : Frontiers in Physiology. 3 OCT, Article 398.

Research output: Contribution to journalArticle

16 Scopus citations

Parallel changes in neuronal at1r and grk5 expression following exercise training in heart failure

Haack, K. K. V., Engler, C. W., Papoutsi, E., Pipinos, I. I., Patel, K. P. & Zucker, I. H., Aug 2012, In : Hypertension. 60, 2, p. 354-361 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Statin therapy lowers muscle sympathetic nerve activity and oxidative stress in patients with heart failure

Deo, S. H., Fisher, J. P., Vianna, L. C., Kim, A., Chockalingam, A., Zimmerman, M. C., Zucker, I. H. & Fadel, P. J., Aug 1 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 303, 3, p. 377-385 9 p.

Research output: Contribution to journalArticle

45 Scopus citations
2011
44 Scopus citations

Central angiotensin (1-7) enhances baroreflex gain in conscious rabbits with heart failure

Kar, S., Gao, L., Belatti, D. A., Curry, P. L. & Zucker, I. H., Oct 2011, In : Hypertension. 58, 4, p. 627-634 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Endogenous reactive oxygen species modulates voltage-gated sodium channels in dorsal root ganglia of rats

Wang, H. J., Li, Y. L., Zhang, L. B., Zucker, I. H., Gao, L., Zimmerman, M. C. & Wang, W., May 2011, In : Journal of Applied Physiology. 110, 5, p. 1439-1447 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Renal denervation modulates angiotensin receptor expression in the renal cortex of rabbits with chronic heart failure

Clayton, S. C., Haack, K. K. V. & Zucker, I. H., Jan 2011, In : American Journal of Physiology - Renal Physiology. 300, 1, p. F31-F39

Research output: Contribution to journalArticle

63 Scopus citations
2010

Alteration in skeletal muscle afferents in rats with chronic heart failure

Wang, H. J., Li, Y. L., Gao, L., Zucker, I. H. & Wang, W., Dec 2010, In : Journal of Physiology. 588, 24, p. 5033-5047 15 p.

Research output: Contribution to journalArticle

54 Scopus citations
46 Scopus citations

Developmental changes in AT1 and AT2 receptor-protein expression in rats

Yu, L., Zheng, M., Wang, W., Rozanski, G. J., Zucker, I. H. & Gao, L., Dec 2010, In : JRAAS - Journal of the Renin-Angiotensin-Aldosterone System. 11, 4, p. 214-221 8 p.

Research output: Contribution to journalArticle

43 Scopus citations