Janet M Guthmiller, DDS, PhD

  • 2452 Citations
  • 23 h-Index
1985 …2019

Research output per year

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Research Output

  • 2452 Citations
  • 23 h-Index
  • 38 Article
  • 3 Comment/debate
  • 3 Review article
  • 1 Chapter
2019

Computational Models Accurately Predict Multi-Cell Biomarker Profiles in Inflammation and Cancer

Fischer, C. L., Bates, A. M., Lanzel, E. A., Guthmiller, J. M., Johnson, G. K., Singh, N. K., Kumar, A., Vidva, R., Abbasi, T., Vali, S., Xie, X. J., Zeng, E. & Brogden, K. A., Dec 1 2019, In : Scientific reports. 9, 1, 10877.

Research output: Contribution to journalArticle

Open Access

Dataset on the chemokine and cytokine responses of multi-cell cultures treated with Porphyromonas gingivalis hemagglutinin B

Abhyankar, V. P., Bates, A. M., Fischer, C. L., Johnson, G. K., Guthmiller, J. M., Progulske-Fox, A. & Brogden, K. A., Feb 2019, In : Data in Brief. 22, p. 964-970 7 p.

Research output: Contribution to journalArticle

2018

Matrix metalloproteinase response of dendritic cell, gingival epithelial keratinocyte, and T-cell transwell co-cultures treated with porphyromonas gingivalis hemagglutinin-B

Bates, A. M., Fischer, C. L., Abhyankar, V. P., Johnson, G. K., Guthmiller, J. M., Progulske-Fox, A. & Brogden, K. A., Dec 2018, In : International journal of molecular sciences. 19, 12, 3923.

Research output: Contribution to journalArticle

5 Scopus citations

Promise of Combining Antifungal Agents in Denture Adhesives to Fight Candida Species Infections

Garaicoa, J. L., Fischer, C. L., Bates, A. M., Holloway, J., Avila-Ortiz, G., Guthmiller, J. M., Johnson, G. K., Stanford, C. & Brogden, K. A., Oct 2018, In : Journal of Prosthodontics. 27, 8, p. 755-762 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Moving out to move up

Guthmiller, J. M., Mar 18 2016, Management and Leadership Skills for Medical Faculty: A Practical Handbook. Springer International Publishing, p. 249-257 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Predicting PD-L1 expression on human cancer cells using next-generation sequencing information in computational simulation models

Lanzel, E. A., Paula Gomez Hernandez, M., Bates, A. M., Treinen, C. N., Starman, E. E., Fischer, C. L., Parashar, D., Guthmiller, J. M., Johnson, G. K., Abbasi, T., Vali, S. & Brogden, K. A., Dec 1 2016, In : Cancer Immunology, Immunotherapy. 65, 12, p. 1511-1522 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
2015

Coordinated Pediatric and Periodontal Dental Care of a Child with Down syndrome

Byrd, G., Quinonez, R. B., Offenbacher, S., Keels, M. A. & Guthmiller, J. M., Jul 1 2015, In : Pediatric dentistry. 37, 4, p. 381-385 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cytotoxicity of HBD3 for dendritic cells, normal human epidermal keratinocytes, hTERT keratinocytes, and primary oral gingival epithelial keratinocytes in cell culture conditions

Leelakanok, N., Fischer, C. L., Bates, A. M., Guthmiller, J. M., Johnson, G. K., Salem, A. K., Brogden, K. A. & Brogden, N. K., Dec 3 2015, In : Toxicology Letters. 239, 2, p. 90-96 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Differential cytotoxicity of long-chain bases for human oral gingival epithelial keratinocytes, oral fibroblasts, and dendritic cells

Poulsen, C., Mehalick, L. A., Fischer, C. L., Lanzel, E. A., Bates, A. M., Walters, K. S., Cavanaugh, J. E., Guthmiller, J. M., Johnson, G. K., Wertz, P. W. & Brogden, K. A., Aug 9 2015, In : Toxicology Letters. 237, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Differential cytotoxicity of long-chain bases for human oral gingival epithelial keratinocytes, oral fibroblasts, and dendritic cells

Mehalick, L. A., Poulsen, C., Fischer, C. L., Lanzel, E. A., Bates, A. M., Walters, K. S., Cavanaugh, J. E., Guthmiller, J. M., Johnson, G. K., Wertz, P. W. & Brogden, K. A., Dec 1 2015, In : Data in Brief. 5, p. 285-291 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Educators’ and Applicants’ Views of the Postdoctoral Pediatric Dentistry Admission Process: A Qualitative Study

Ricker, K., Mihas, P., Lee, J. Y., Guthmiller, J. M., Roberts, M. W. & Divaris, K., Nov 1 2015, In : Journal of dental education. 79, 11, p. 1272-1278 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Empowerment through mentorship and leadership

Wilder, R. S. & Guthmiller, J. M., Jun 2014, In : Journal of Evidence-Based Dental Practice. 14, SUPPL., p. 222-226 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

The impact of oral health literacy on periodontal health status

Wehmeyer, M. M. H., Corwin, C. L., Guthmiller, J. M. & Lee, J. Y., Dec 2014, In : Journal of Public Health Dentistry. 74, 1, p. 80-87 8 p.

Research output: Contribution to journalArticle

35 Scopus citations
2012

Quantitation of SPLUNC1 in saliva with an xMAP particle-based antibody capture and detection immunoassay

Kohlgraf, K. G., Ackermann, A. R., Burnell, K. K., Srikantha, R. N., Joly, S. A., Bartlett, J. A., Gakhar, L., Johnson, G. K., McCray, P. B., Guthmiller, J. M. & Brogden, K. A., Feb 2012, In : Archives of Oral Biology. 57, 2, p. 197-204 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Influence of smoking on gingival crevicular fluid cytokines in severe chronic periodontitis

Tymkiw, K. D., Thunell, D. H., Johnson, G. K., Joly, S., Burnell, K. K., Cavanaugh, J. E., Brogden, K. A. & Guthmiller, J. M., Mar 2011, In : Journal of Clinical Periodontology. 38, 3, p. 219-228 10 p.

Research output: Contribution to journalArticle

93 Scopus citations
2010

A multiplex immunoassay demonstrates reductions in gingival crevicular fluid cytokines following initial periodontal therapy

Thunell, D. H., Tymkiw, K. D., Johnson, G. K., Joly, S., Burnell, K. K., Cavanaugh, J. E., Brogden, K. A. & Guthmiller, J. M., Feb 2010, In : Journal of Periodontal Research. 45, 1, p. 148-152 5 p.

Research output: Contribution to journalArticle

88 Scopus citations

Interleukin-1 and interleukin-8 in nicotine- and lipopolysaccharide-exposed gingival keratinocyte cultures

Johnson, G. K., Guthmiller, J. M., Joly, S., Organ, C. C. & Dawson, D. V., Aug 2010, In : Journal of Periodontal Research. 45, 4, p. 583-588 6 p.

Research output: Contribution to journalArticle

24 Scopus citations
2009

Erratum: Periodontal-Systemic Disease Education in U.S. and Canadian Dental Schools (Journal of Dental Education (2009) 73:1 (38-52))

Wilder, R. S., Iacopino, A. M., Feldman, C. A., Guthmiller, J., Linfante, J., Lavigne, S. & Paquette, D., May 1 2009, In : Journal of dental education. 73, 5, p. e1

Research output: Contribution to journalComment/debate

Loss of human β-defensin 1, 2, and 3 expression in oral squamous cell carcinoma

Joly, S., Compton, L. M., Pujol, C., Kurago, Z. B. & Guthmiller, J. M., Oct 2009, In : Oral Microbiology and Immunology. 24, 5, p. 353-360 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

Periodontal-systemic disease education in U.S. and Canadian dental schools

Wilder, R. S., Iacopino, A. M., Feldman, C. A., Guthmiller, J., Linfante, J., Lavigne, S. & Paquette, D., Jan 1 2009, In : Journal of dental education. 73, 1, p. 38-52 15 p.

Research output: Contribution to journalArticle

20 Scopus citations

Targeted antimicrobial activity of a specific IgG-SMAP28 conjugate against Porphyromonas gingivalis in a mixed culture

Franzman, M. R., Burnell, K. K., Dehkordi-Vakil, F. H., Guthmiller, J. M., Dawson, D. V. & Brogden, K. A., Jan 2009, In : International Journal of Antimicrobial Agents. 33, 1, p. 14-20 7 p.

Research output: Contribution to journalArticle

26 Scopus citations
2008

Human β-defensin 3 binds to hemagglutinin B (rHagB), a non-fimbrial adhesin from Porphyromonas gingivalis, and attenuates a pro-inflammatory cytokine response

Pingel, L. C., Kohlgraf, K. G., Hansen, C. J., Eastman, C. G., Dietrich, D. E., Burnell, K. K., Srikantha, R. N., Xiao, X., Bélanger, M., Progulske-Fox, A., Cavanaugh, J. E., Guthmiller, J. M., Johnson, G. K., Joly, S., Kurago, Z. B., Dawson, D. V. & Brogden, K. A., Nov 2008, In : Immunology and Cell Biology. 86, 8, p. 643-649 7 p.

Research output: Contribution to journalArticle

56 Scopus citations

SMAP29 congeners demonstrate activity against oral bacteria and reduced toxicity against oral keratinocytes

Weistroffer, P. L., Joly, S., Srikantha, R., Tack, B. F., Brogden, K. A. & Guthmiller, J. M., Apr 2008, In : Oral Microbiology and Immunology. 23, 2, p. 89-95 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2007

Intravenous bisphosphonate-associated osteonecrosis of the jaw

Statz, T. A., Guthmiller, J. M., Humbert, L. A. & Johnson, G. K., Nov 2007, In : Journal of periodontology. 78, 11, p. 2203-2208 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

The impact of cigarette smoking on periodontal disease and treatment

Johnson, G. K. & Guthmiller, J. M., Jun 2007, In : Periodontology 2000. 44, 1, p. 178-194 17 p.

Research output: Contribution to journalReview article

189 Scopus citations
2005

Correlation between β-defensin expression and induction profiles in gingival keratinocytes

Joly, S., Organ, C. C., Johnson, G. K., McCray, P. B. & Guthmiller, J. M., May 2005, In : Molecular Immunology. 42, 9, p. 1073-1084 12 p.

Research output: Contribution to journalArticle

105 Scopus citations

Factors related to utilization of dental services during pregnancy

Habashneh, R. A., Guthmiller, J. M., Levy, S., Johnson, G. K., Squier, C., Dawson, D. V. & Fang, Q., Jul 2005, In : Journal of Clinical Periodontology. 32, 7, p. 815-821 7 p.

Research output: Contribution to journalArticle

87 Scopus citations

Human polymicrobial infections

Brogden, K. A., Guthmiller, J. M. & Taylor, C. E., Jan 15 2005, In : Lancet. 365, 9455, p. 253-255 3 p.

Research output: Contribution to journalReview article

189 Scopus citations

The nervous system and innate immunity: The neuropeptide connection

Brogden, K. A., Guthmiller, J. M., Salzet, M. & Zasloff, M., 2005, In : Nature Immunology. 6, 6, p. 558-564 7 p.

Research output: Contribution to journalReview article

188 Scopus citations
2004

Expression and regulation of novel human β-defensins in gingival keratinocytes

Premratanachai, P., Joly, S., Johnson, G. K., McCray, P. B., Jia, H. P. & Guthmiller, J. M., Apr 2004, In : Oral Microbiology and Immunology. 19, 2, p. 111-117 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Expression of β-defensins in gingival health and in periodontal disease

Bissell, J., Joly, S., Johnson, G. K., Organ, C. C., Dawson, D., McCray, P. B. & Guthmiller, J. M., May 2004, In : Journal of Oral Pathology and Medicine. 33, 5, p. 278-285 8 p.

Research output: Contribution to journalArticle

82 Scopus citations

Human β-Defensins 2 and 3 Demonstrate Strain-Selective Activity against Oral Microorganisms

Joly, S., Maze, C., McCray, P. B. & Guthmiller, J. M., Mar 2004, In : Journal of clinical microbiology. 42, 3, p. 1024-1029 6 p.

Research output: Contribution to journalArticle

196 Scopus citations
2003

Bacterial penetration through canals of endodontically treated teeth in the presence or absence of the smear layer

Clark-Holke, D., Drake, D., Walton, R., Rivera, E. & Guthmiller, J. M., May 2003, In : Journal of Dentistry. 31, 4, p. 275-281 7 p.

Research output: Contribution to journalArticle

80 Scopus citations

Defensin-induced adaptive immunity in mice and its potential in preventing periodontal disease

Brogden, K. A., Heidari, M., Sacco, R. E., Palmquist, D., Guthmiller, J. M., Johnson, G. K., Jia, H. P., Tack, B. F. & McCray, P. B., Apr 2003, In : Oral Microbiology and Immunology. 18, 2, p. 95-99 5 p.

Research output: Contribution to journalArticle

85 Scopus citations
2001
Open Access
38 Scopus citations

Discovery of new human β-defensins using a genomics-based approach

Peng Jia, H., Schutte, B. C., Schudy, A., Linzmeier, R., Guthmiller, J. M., Johnson, G. K., Tack, B. F., Mitros, J. P., Rosenthal, A., Ganz, T. & McCray, P. B., Jan 24 2001, In : Gene. 263, 1-2, p. 211-218 8 p.

Research output: Contribution to journalArticle

228 Scopus citations

Molecular Analysis of Peptostreptococcus micros Isolates from Patients with Periodontitis

Alpha, C. X., Guthmiller, J. M., Cummings, H. E., Schomberg, L. L. & Noorani, S. M., Jul 2001, In : Journal of periodontology. 72, 7, p. 877-882 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Periodontal disease in pregnancy complicated by type 1 diabetes mellitus

Guthmiller, J. M., Hassebroek-Johnson, J. R., Weenig, D. R., Johnson, G. K., Kirchner, H. L., Kohout, F. J. & Hunter, S. K., 2001, In : Journal of periodontology. 72, 11, p. 1485-1490 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Susceptibilities of oral bacteria and yeast to mammalian cathelicidins

Guthmiller, J. M., Vargas, K. G., Srikantha, R., Schomberg, L. L., Weistroffer, P. L., McCray, J. & Tack, B. F., 2001, In : Antimicrobial Agents and Chemotherapy. 45, 11, p. 3216-3219 4 p.

Research output: Contribution to journalArticle

56 Scopus citations
1999

Production of β-defensin antimicrobial peptides by the oral mucosa and salivary glands

Mathews, M., Jia, H. P., Guthmiller, J. M., Losh, G., Graham, S., Johnson, G. K., Tack, B. F. & McCray, P. B., Jun 1999, In : Infection and immunity. 67, 6, p. 2740-2745 6 p.

Research output: Contribution to journalArticle

Open Access
303 Scopus citations
1996

Development and evaluation of a selective and differential medium for the primary isolation of Peptostreptococcus micros

Turng, B. F., Guthmiller, J. M., Minah, G. E. & Falkler, W. A., Oct 1996, In : Oral Microbiology and Immunology. 11, 5, p. 356-361 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
1995

Mutational analysis of the putative leukotoxin transport genes in actinobacillus actinomycetemcomitans

Guthmiller, J. M., Kolodrubetz, D. & Kraig, E., May 1995, In : Microbial Pathogenesis. 18, 5, p. 307-321 15 p.

Research output: Contribution to journalArticle

30 Scopus citations
1993
15 Scopus citations
1990

Sequence of the IktB gene from Actinobacillus actinomycetemcomitans

Guthmiller, J. M., Kolodrubetz, D., Cagle, M. P. & Kraig, E., Sep 11 1990, In : Nucleic acids research. 18, 17, 1 p.

Research output: Contribution to journalComment/debate

24 Scopus citations

Sequence of the IktD gene from Actinobacillus actinomycetemcomitans

Guthmiller, J. M., Kraig, E., Cagle, M. P. & Kolodrubetz, D., Sep 11 1990, In : Nucleic acids research. 18, 17, 1 p.

Research output: Contribution to journalComment/debate

20 Scopus citations