Research output per year
Research output per year
Personal profile
Research interests
One of the major objectives of Dr. Siddiqui's laboratory is to elucidate biological mechanisms underlying bone metastasis of different malignancies. Dr. Siddiqui's lab has developed unique techniques and experimental models that allow us to decipher bone metastasis. Metastatic tumors attain the skill to blunt or overturn the functions of the immune system. His lab study how cancer cells influence bone resident macrophages for their colonization and growth within the bone microenvironment and design therapeutic strategies accordingly.
Current projects :
- Molecular mechanism of bone metastasis (Prostate, Breast, and Lung cancer)
- Bone Microenvironment
- Osteoimmunology and Tumor Dormancy.
- Development of the Bone metastasis Therapeutics
External positions
Member, Child Health Research Institute
Member, Fred and Pamela Buffet Cancer Center
Research interests
- Metastasis
- cancer cachexia
- Bone
- Bone metastasis
Special Topics
- therapeutics
- Osteoblasts
- Osteoimmunology
Fingerprint
Dive into the research topics where Jawed A Siddiqui is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Advances in cancer cachexia: Intersection between affected organs, mediators, and pharmacological interventions
Siddiqui, J. A., Pothuraju, R., Jain, M., Batra, S. K. & Nasser, M. W., Apr 2020, In: Biochimica et Biophysica Acta - Reviews on Cancer. 1873, 2, 188359.Research output: Contribution to journal › Review article › peer-review
Open Access64 Scopus citations -
Osteoblastic Monocyte Chemoattractant Protein-1 (MCP-1) Mediation of Parathyroid Hormone's Anabolic Actions in Bone Implicates TGF-β Signaling.
Siddiqui, J. A., Nov 16 2020, In: Bone.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
RNA-based therapies: A cog in the wheel of lung cancer defense
Khan, P., Siddiqui, J. A., Lakshmanan, I., Ganti, A. K., Salgia, R., Jain, M., Batra, S. K. & Nasser, M. W., Dec 2021, In: Molecular cancer. 20, 1, 54.Research output: Contribution to journal › Review article › peer-review
Open Access61 Scopus citations -
Epigenetic landscape of small cell lung cancer: small image of a giant recalcitrant disease.
Siddiqui, J. A., Nov 18 2020, In: Seminars in Cancer Biology.Research output: Contribution to journal › Article › peer-review
-
MicroRNAs Orchestrate Pathophysiology of Breast Cancer Brain Metastasis: Advances in Therapy
Kanchan, R. K., Siddiqui, J. A., Mahapatra, S., Batra, S. K. & Nasser, M. W., Feb 15 2020, In: Molecular cancer. 19, 1, 29.Research output: Contribution to journal › Review article › peer-review
Open Access55 Scopus citations