• 4205 Citations
  • 34 h-Index
1978 …2020

Research output per year

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Research Output

  • 4205 Citations
  • 34 h-Index
  • 71 Article
  • 6 Review article
  • 3 Comment/debate
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Article

Ubiquitin-dependent regulation of phospho-AKT Dynamics by the ubiquitin E3 LIGASE, NEDD4-1, in the insulin-like growth factor-1 response

Fan, C. D., Lum, M. A., Xu, C., Black, J. D. & Wang, X., Jan 18 2013, In : Journal of Biological Chemistry. 288, 3, p. 1674-1684 11 p.

Research output: Contribution to journalArticle

64 Scopus citations

The relationship between smoking exposure and p53 overexpression in colorectal cancer

Freedman, A. N., Michalek, A. M., Marshall, J. R., Mettlin, C. J., Petrelli, N. J., Zhang, Z. F., Black, J. D., Satchidanand, S. & Asirwatham, J. E., Apr 1996, In : British journal of cancer. 73, 8, p. 902-908 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

TGFβ/Smad3 regulates proliferation and apoptosis through IRS-1 inhibition in colon cancer cells

Bailey, K. L., Agarwal, E., Chowdhury, S., Luo, J., Brattain, M. G., Black, J. D. & Wang, J., Apr 2017, In : PloS one. 12, 4, e0176096.

Research output: Contribution to journalArticle

12 Scopus citations

TGF and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells

Leiphrakpam, P. D., Brattain, M. G., Black, J. D. & Wang, J., May 25 2018, In : Journal of Biological Chemistry. 293, 21, p. 8242-8254 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Temporal and spatial expression of TACC1 in the mouse and human

Lauffart, B., DiMatteo, A., Vaughan, M. M., Cincotta, M. A., Black, J. D. & Still, I. H., Jun 2006, In : Developmental Dynamics. 235, 6, p. 1638-1647 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Stimulation of protein kinase C-dependent and -independent signaling pathways by bistratene A in intestinal epithelial cells

Frey, M. R., Leontieva, O., Watters, D. J. & Black, J. D., May 1 2001, In : Biochemical Pharmacology. 61, 9, p. 1093-1100 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

SPAF, a new AAA-protein specific to early spermatogenesis and malignant conversion

Liu, Y., Black, J., Kisiel, N. & Kulesz-Martin, M. F., Mar 16 2000, In : Oncogene. 19, 12, p. 1579-1588 10 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations
2 Scopus citations

Selective location of acceptors for botulinum neurotoxin a in the central and peripheral nervous systems

Black, J. D. & Dolly, J. O., Nov 1987, In : Neuroscience. 23, 2, p. 767-779 13 p.

Research output: Contribution to journalArticle

76 Scopus citations

Selective inhibition of histone deacetylases 1/2/6 in combination with gemcitabine: A promising combination for pancreatic cancer therapy

Laschanzky, R. S., Humphrey, L. E., Ma, J., Smith, L. M., Enke, T. J., Shukla, S. K., Dasgupta, A., Singh, P. K., Howell, G. M., Brattain, M. G., Ly, Q. P., Black, A. R. & Black, J. D., Sep 2019, In : Cancers. 11, 9, 1327.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis

Agarwal, E., Robb, C. M., Smith, L. M., Brattain, M. G., Wang, J., Black, J. D. & Chowdhury, S., Jun 1 2017, In : Oncogene. 36, 22, p. 3104-3118 15 p.

Research output: Contribution to journalArticle

16 Scopus citations

Protein kinase Cα signaling regulates inhibitor of DNA binding 1 in the intestinal epithelium

Hao, F., Pysz, M. A., Curry, K. J., Haas, K. N., Seedhouse, S. J., Black, A. R. & Black, J. D., May 20 2011, In : Journal of Biological Chemistry. 286, 20, p. 18104-18117 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

Protein kinase C α signaling inhibits cyclin D1 translation in intestinal epithelial cells

Hizli, A. A., Black, A. R., Pysz, M. A. & Black, J. D., May 26 2006, In : Journal of Biological Chemistry. 281, 21, p. 14596-14603 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Protein Kinase Cα (PKCα) is resistant to long term desensitization/down-regulation by prolonged diacylglycerol stimulation

Lum, M. A., Barger, C. J., Hsu, A. H., Leontieva, O. V., Black, A. R. & Black, J. D., Mar 18 2016, In : Journal of Biological Chemistry. 291, 12, p. 6331-6346 16 p.

Research output: Contribution to journalArticle

3 Scopus citations

Protein kinase C signaling mediates a program of cell cycle withdrawal in the intestinal epithelium

Frey, M. R., Clark, J. A., Leontieva, O., Uronis, J. M., Black, A. R. & Black, J. D., Nov 13 2000, In : Journal of Cell Biology. 151, 4, p. 763-777 15 p.

Research output: Contribution to journalArticle

86 Scopus citations
65 Scopus citations

Protein kinase C isozymes in colon carcinogenesis: Guilt by omission

Black, J. D., 2001, In : Gastroenterology. 120, 7, p. 1868-1872 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

Protein kinase C isozyme-mediated cell cycle arrest involves induction of p21(waf1/cip1) and p27(kip1) and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells

Frey, M. R., Saxon, M. L., Zhao, X., Rollins, A., Evans, S. S. & Black, J. D., Apr 4 1997, In : Journal of Biological Chemistry. 272, 14, p. 9424-9435 12 p.

Research output: Contribution to journalArticle

121 Scopus citations

Prolactin and epidermal growth factor regulation of the proliferation, morphogenesis, and functional differentiation of normal rat mammary epithelial cells in three dimensional primary culture

Darcy, K. M., Shoemaker, S. F., Lee, PP. H., Vaughan, M. M., Black, J. D. & Ip, M. M., May 1995, In : Journal of Cellular Physiology. 163, 2, p. 346-364 19 p.

Research output: Contribution to journalArticle

26 Scopus citations

Prognostic and therapeutic implications of NHERF1 expression and regulation in colorectal cancer

Leiphrakpam, P. D., Lazenby, A. J., Chowdhury, S., Smith, L. M., Mathiesen, M., Brattain, M. G., Wang, J., Black, J. D. & Are, C., Mar 1 2020, In : Journal of Surgical Oncology. 121, 3, p. 547-560 14 p.

Research output: Contribution to journalArticle

Primary culture of normal rat mammary epithelial cells within a basement membrane matrix. II. Functional differentiation under serum-free conditions

Hahm, H. A., Ip, M. M., Darcy, K., Black, J. D., Shea, W. K., Forczek, S., Yoshimura, M. & Oka, T., Aug 1990, In : In Vitro Cellular &Developmental Biology. 26, 8, p. 803-814 12 p.

Research output: Contribution to journalArticle

43 Scopus citations

Polyamine analogue-mediated cell cycle responses in human melanoma cells involves the p53, p21, Rb regulatory pathway

Kramer, D. L., Vujcic, S., Diegelman, P., White, C., Black, J. D. & Porter, C. W., 1998, In : Biochemical Society Transactions. 26, 4, p. 609-614 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Polyamine analogue induction of the p53-p21(WAF1/CIP1)-Rb pathway and G1 Ar in human melanoma cells

Kramer, D. L., Vujcic, S., Diegelman, P., Alderfer, J., Miller, J. T., Black, J. D., Bergeron, R. J. & Porter, C. W., Mar 15 1999, In : Cancer Research. 59, 6, p. 1278-1286 9 p.

Research output: Contribution to journalArticle

104 Scopus citations
6 Scopus citations

PKCα tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1

Pysz, M. A., Leontieva, O. V., Bateman, N. W., Uronis, J. M., Curry, K. J., Threadgill, D. W., Janssen, K. P., Robine, S., Velcich, A., Augenlicht, L. H., Black, A. R. & Black, J. D., May 1 2009, In : Experimental Cell Research. 315, 8, p. 1415-1428 14 p.

Research output: Contribution to journalArticle

27 Scopus citations

Pilot study of gefitinib, oxaliplatin, and radiotherapy for esophageal adenocarcinoma tissue effect predicts clinical response

Javle, M., Pande, A., Iyer, R., Yang, G., LeVea, C., Wilding, G., Black, J., Nava, H. & Nwogu, C., Aug 2008, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 31, 4, p. 329-334 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Morphological study of murine T and B lymphocyte spectrin distribution in untreated and activated cells

Verstovsek, G., Repasky, E. A. & Black, J. D., 1994, In : Periodicum Biologorum. 96, 1, p. 51-52 2 p.

Research output: Contribution to journalArticle

Morphological Evidence for an Apparent Lysosomotropic Activity by Unsaturated Putrescine Analogues

Black, J., Ganis, B., Pleshkewych, A., Porter, C. W., Vaughan, M. & Stanek, J., Mar 15 1990, In : Cancer Research. 50, 6, p. 1929-1935 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Mammary organoids from immature virgin rats undergo ductal and alveolar morphogenesis when grown within a reconstituted basement membrane

Darcy, K. M., Black, J. D., Hahm, H. A. & Ip, M. M., Sep 1991, In : Experimental Cell Research. 196, 1, p. 49-65 17 p.

Research output: Contribution to journalArticle

42 Scopus citations

Lysosomal sequestration of polyamine analogues in Chinese hamster ovary cells resistant to the S-adenosylmethionine decarboxylase inhibitor, CGP- 48664

Kramer, D. L., Black, J. D., Mett, H., Bergeron, R. J. & Porter, C. W., Sep 1 1998, In : Cancer Research. 58, 17, p. 3883-3890 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Localization of sites for 125I-labelled botulinum neurotoxin at murine neuromuscular junction and its binding to rat brain synaptosomes

Dolly, J. O., Williams, R. S., Black, J. D., Tse, C. K., Hambleton, P. & Melling, J., 1982, In : Toxicon. 20, 1, p. 141-148 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Involvement of the ERK Signaling Cascade in Protein Kinase C-mediated Cell Cycle Arrest in Intestinal Epithelial Cells

Clark, J. A., Black, A. R., Leontieva, O. V., Frey, M. R., Pysz, M. A., Kunneva, L., Woloszynska-Read, A., Roy, D. & Black, J. D., Mar 5 2004, In : Journal of Biological Chemistry. 279, 10, p. 9233-9247 15 p.

Research output: Contribution to journalArticle

59 Scopus citations

Intestinal Tumor Progression Is Associated with Altered Function of KLF5

Bateman, N. W., Tan, D., Pestell, R. G., Black, J. D. & Black, A. R., Mar 26 2004, In : Journal of Biological Chemistry. 279, 13, p. 12093-12101 9 p.

Research output: Contribution to journalArticle

104 Scopus citations

Intestinal trefoil factor (TFF-3) and extracellular signal-regulated kinase (ERK) in cholangiocarcinoma

Ailawadhi, S., Nagase, H., Khoury, T., Yu, J., Tan, D., Black, J., Brattain, M. & Javle, M., Jul 2007, In : Hepato-Gastroenterology. 54, 77, p. 1339-1344 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Interleukin 15 offers selective protection from irinotecan-induced intestinal toxicity in a preclinical animal model

Cao, S., Black, J. D., Troutt, A. B. & Rustum, Y. M., Aug 1 1998, In : Cancer Research. 58, 15, p. 3270-3274 5 p.

Research output: Contribution to journalArticle

54 Scopus citations
Open Access
211 Scopus citations
192 Scopus citations

Inhibition of Messenger RNA Transcriptional Activity in ML-1 Human Myeloblastic Leukemia Cell Nuclei by Antiserum to a c-myb-specific Peptide

Honma, Y., Hozumi, M., Black, J. D. & Kieber-Emmons, T., Feb 1987, In : Cancer Research. 47, 4, p. 1052-1057 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of Two Distinct Pathways of Protein Kinase Cα Down-regulation in Intestinal Epithelial Cells

Leontieva, O. V. & Black, J. D., Feb 13 2004, In : Journal of Biological Chemistry. 279, 7, p. 5788-5801 14 p.

Research output: Contribution to journalArticle

84 Scopus citations

Heterogeneity in lymphocyte spectrin distribution: Ultrastructural identification of a new spectrin-rich cytoplasmic structure

Black, J. D., Koury, S. T., Bankert, R. B. & Repasky, E. A., 1988, In : Journal of Cell Biology. 106, 1, p. 97-109 13 p.

Research output: Contribution to journalArticle

Open Access
63 Scopus citations

Heat shock proteins regulate activation-induced proteasomal degradation of the mature phosphorylated form of protein kinase C

Lum, M. A., Balaburski, G. M., Murphy, M. E., Black, A. R. & Black, J. D., Sep 20 2013, In : Journal of Biological Chemistry. 288, 38, p. 27112-27127 16 p.

Research output: Contribution to journalArticle

11 Scopus citations

Growth of human renal cortical tissue on collagen gel

Chang, S. G., Toth, K., Black, J. D., Slocum, H. K., Perrapato, S. D., Huben, R. P. & Rustum, Y. M., 1992, In : In Vitro Cellular and Developmental Biology - Animal. 28 A, 2, p. 128-135 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
39 Scopus citations

Eukaryotic initiation factor-4E and cyclin D1 expression associated with patient survival in lung cancer

Khoury, T., Alrawi, S., Ramnath, N., Li, Q., Grimm, M., Black, J. & Tan, D., Jan 2009, In : Clinical Lung Cancer. 10, 1, p. 58-66 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Epithelial-Mesenchymal Transition (EMT) and activated extracellular signal-regulated kinase (p-Erk) in surgically resected pancreatic cancer

Javle, M. M., Gibbs, J. F., Iwata, K. K., Pak, Y., Rutledge, P., Yu, J., Black, J. D., Tan, D. & Khoury, T., Dec 2007, In : Annals of Surgical Oncology. 14, 12, p. 3527-3533 7 p.

Research output: Contribution to journalArticle

126 Scopus citations

Epidermal growth factor receptor expression correlates with histologic grade in resected esophageal adenocarcinoma

Wilkinson, N. W., Black, J. D., Roukhadze, E., Driscoll, D., Smiley, S., Hoshi, H., Geradts, J., Javle, M. & Brattain, M., May 2004, In : Journal of Gastrointestinal Surgery. 8, 4, p. 448-453 6 p.

Research output: Contribution to journalArticle

77 Scopus citations

Elevated Expression of the Serine-Arginine Protein Kinase 1 Gene in Ovarian Cancer and Its Role in Cisplatin Cytotoxicity In Vitro

Odunsi, K., Mhawech-Fauceglia, P., Andrews, C., Beck, A., Amuwo, O., Lele, S., Black, J. D. & Huang, R. Y., Dec 7 2012, In : PloS one. 7, 12, e51030.

Research output: Contribution to journalArticle

32 Scopus citations

Effects of botulinum neurotoxin and Lambert-Eaton myasthenic syndrome IgG at mouse nerve terminals

Lande, S., Black, J., Dolly, J. O., Lang, B., Newsom-Davis, J. & -Wray, D. W., Sep 1989, In : Journal of Neural Transmission - Parkinson's Disease and Dementia Section. 1, 3, p. 229-242 14 p.

Research output: Contribution to journalArticle

Dynamic properties of ankyrin in T lymphocytes: Colocalization with spectrin and protein kinase Cβ

Gregorio, C. C., Repasky, E. A., Fowler, V. M. & Black, J. D., Apr 1994, In : Journal of Cell Biology. 125, 2, p. 345-358 14 p.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations

Dynamic association of L-selectin with the lymphocyte cytoskeletal matrix

Evans, S. S., Schleider, D. M., Bowman, L. A., Francis, M. L., Kansas, G. S. & Black, J. D., Mar 15 1999, In : Journal of Immunology. 162, 6, p. 3615-3624 10 p.

Research output: Contribution to journalArticle

60 Scopus citations