Junguk Hur, PhD

  • 2103 Citations
  • 21 h-Index
20042020

Research output per year

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Research Output

2020

CIDO, a community-based ontology for coronavirus disease knowledge and data integration, sharing, and analysis

He, Y., Yu, H., Ong, E., Wang, Y., Liu, Y., Huffman, A., Huang, H. H., Beverley, J., Hur, J., Yang, X., Chen, L., Omenn, G. S., Athey, B. & Smith, B., Dec 1 2020, In : Scientific Data. 7, 1, 181.

Research output: Contribution to journalComment/debate

Open Access

Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis

Paez-Colasante, X., Figueroa-Romero, C., Rumora, A. E., Hur, J., Mendelson, F. E., Hayes, J. M., Backus, C., Taubman, G. F., Heinicke, L., Walter, N. G., Barmada, S. J., Sakowski, S. A. & Feldman, E. L., May 12 2020, In : Frontiers in Cellular Neuroscience. 14, 117.

Research output: Contribution to journalArticle

Open Access

Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes

O’Brien, P. D., Guo, K., Eid, S. A., Rumora, A. E., Hinder, L. M., Hayes, J. M., Mendelson, F. E., Hur, J. & Feldman, E. L., 2020, In : DMM Disease Models and Mechanisms. 13, 2, dmm042101.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice

Figueroa-Romero, C., Guo, K., Murdock, B. J., Paez-Colasante, X., Bassis, C. M., Mikhail, K. A., Raue, K. D., Evans, M. C., Taubman, G. F., McDermott, A. J., O'Brien, P. D., Savelieff, M. G., Hur, J. & Feldman, E. L., 2020, In : DMM Disease Models and Mechanisms. 13, 2, dmm041947.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2019

A 2018 workshop: Vaccine and drug ontology studies (VDOS 2018)

Hur, J., Tao, C. & He, Y., Dec 23 2019, In : BMC bioinformatics. 20, 705.

Research output: Contribution to journalReview article

Open Access

A computational platform and guide for acceleration of novel medicines and personalized medicine

Melas, I. N., Sakellaropoulos, T., Hur, J., Messinis, D., Guo, E. Y., Alexopoulos, L. G. & Bai, J. P. F., 2019, Methods in Molecular Biology. Humana Press Inc., p. 181-198 18 p. (Methods in Molecular Biology; vol. 1939).

Research output: Chapter in Book/Report/Conference proceedingChapter

A Network Pharmacology Approach for the Identification of Common Mechanisms of Drug-Induced Peripheral Neuropathy

de Anda-Jáuregui, G., McGregor, B. A., Guo, K. & Hur, J., Apr 2019, In : CPT: Pharmacometrics and Systems Pharmacology. 8, 4, p. 211-219 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
Open Access

Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus

Guo, K., Elzinga, S., Eid, S., Figueroa-Romero, C., Hinder, L. M., Pacut, C., Feldman, E. L. & Hur, J., Aug 3 2019, In : Epigenetics. 14, 8, p. 766-779 14 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Identification of Casiopeina II-gly secondary targets through a systems pharmacology approach

de Anda-Jáuregui, G., Espinal-Enríquez, J., Hur, J., Alcalá-Corona, S. A., Ruiz-Azuara, L. & Hernández-Lemus, E., Feb 2019, In : Computational Biology and Chemistry. 78, p. 127-132 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Machine learning-based identification and rule-based normalization of adverse drug reactions in drug labels

Tiftikci, M., Özgür, A., He, Y. & Hur, J., Dec 23 2019, In : BMC bioinformatics. 20, 707.

Research output: Contribution to journalArticle

Open Access

Network-based assessment of adverse drug reaction risk in polypharmacy using high-throughput screening data

de Anda-Jáuregui, G., Guo, K. & Hur, J., Jan 2 2019, In : International journal of molecular sciences. 20, 2, 386.

Research output: Contribution to journalArticle

1 Scopus citations

Pathway crosstalk perturbation network modeling for identification of connectivity changes induced by diabetic neuropathy and pioglitazone

de Anda-Jáuregui, G., Guo, K., McGregor, B. A., Feldman, E. L. & Hur, J., Jan 7 2019, In : BMC systems biology. 13, 1, 1.

Research output: Contribution to journalArticle

4 Scopus citations

Toll-like receptors and inflammation in metabolic neuropathy; a role in early versus late disease?

Elzinga, S., Murdock, B. J., Guo, K., Hayes, J. M., Tabbey, M. A., Hur, J. & Feldman, E. L., Oct 2019, In : Experimental Neurology. 320, 112967.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Abnormal RNA stability in amyotrophic lateral sclerosis

Tank, E. M., Figueroa-Romero, C., Hinder, L. M., Bedi, K., Archbold, H. C., Li, X., Weskamp, K., Safren, N., Paez-Colasante, X., Pacut, C., Thumma, S., Paulsen, M. T., Guo, K., Hur, J., Ljungman, M., Feldman, E. L. & Barmada, S. J., Dec 1 2018, In : Nature communications. 9, 1, 2845.

Research output: Contribution to journalArticle

21 Scopus citations

Acute Biophysical Responses and Psychological Effects of Different Types of Forests in Patients With Metabolic Syndrome

Lee, K. J., Hur, J., Yang, K. S., Lee, M. K. & Lee, S. J., Apr 1 2018, In : Environment and Behavior. 50, 3, p. 298-323 26 p.

Research output: Contribution to journalArticle

4 Scopus citations

Advances in omics for informed pharmaceutical research and development in the era of systems medicine

Bai, J. P. F., Melas, I. N., Hur, J. & Guo, E., Jan 2 2018, In : Expert Opinion on Drug Discovery. 13, 1, p. 1-4 4 p.

Research output: Contribution to journalEditorial

3 Scopus citations
3 Scopus citations

Conserved Transcriptional Signatures in Human and Murine Diabetic Peripheral Neuropathy

McGregor, B. A., Eid, S., Rumora, A. E., Murdock, B., Guo, K., de Anda-Jáuregui, G., Porter, J. E., Feldman, E. L. & Hur, J., Dec 1 2018, In : Scientific reports. 8, 1, 17678.

Research output: Contribution to journalArticle

13 Scopus citations

Exploration of the anti-inflammatory drug space through network pharmacology: Applications for drug repurposing

de Anda-Jáuregui, G., Guo, K., McGregor, B. A. & Hur, J., Mar 1 2018, In : Frontiers in Physiology. 9, MAR, 151.

Research output: Contribution to journalArticle

7 Scopus citations
3 Scopus citations

Tox21 Enricher: Web-based Chemical/Biological Functional Annotation Analysis Tool Based on Tox21 Toxicity Screening Platform

Hur, J., Danes, L., Hsieh, J. H., McGregor, B., Krout, D. & Auerbach, S., May 2018, In : Molecular Informatics. 37, 5, 1700129.

Research output: Contribution to journalComment/debate

4 Scopus citations

Transcriptional networks of progressive diabetic peripheral neuropathy in the db/db mouse model of type 2 diabetes: An inflammatory story

Hinder, L. M., Murdock, B. J., Park, M., Bender, D. E., O'Brien, P. D., Rumora, A. E., Hur, J. & Feldman, E. L., Jul 2018, In : Experimental Neurology. 305, p. 33-43 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Translational systems pharmacology-based predictive assessment of drug-induced cardiomyopathy

Messinis, DI. E., Melas, I. N., Hur, J., Varshney, N., Alexopoulos, L. G. & Bai, J. P. F., Mar 2018, In : CPT: Pharmacometrics and Systems Pharmacology. 7, 3, p. 166-174 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Trends of self-reported sleep duration in Korean Adults: results from the Korea National Health and Nutrition Examination Survey 2007–2015

Shin, D., Hur, J., Cho, K. H. & Cho, E. H., Dec 2018, In : Sleep Medicine. 52, p. 103-106 4 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation

Witt, K. L., Hsieh, J. H., Smith-Roe, S. L., Xia, M., Huang, R., Zhao, J., Auerbach, S. S., Hur, J. & Tice, R. R., Aug 2017, In : Environmental and Molecular Mutagenesis. 58, 7, p. 494-507 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Comparative RNA-Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease

Hinder, L. M., Park, M., Rumora, A. E., Hur, J., Eichinger, F., Pennathur, S., Kretzler, M., Brosius, F. C. & Feldman, E. L., Sep 2017, In : Journal of cellular and molecular medicine. 21, 9, p. 2140-2152 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Ontology-based literature mining of E. coli vaccine-associated gene interaction networks

Hur, J., Özgür, A. & He, Y., Mar 14 2017, In : Journal of Biomedical Semantics. 8, 1, 12.

Research output: Contribution to journalArticle

5 Scopus citations

Prediction of gestational diabetes mellitus by unconjugated estriol levels in maternal serum

Hur, J., Cho, E. H., Baek, K. H. & Lee, K. J., Feb 7 2017, In : International Journal of Medical Sciences. 14, 2, p. 123-127 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Pre‐pregnancy body mass index is associated with dietary inflammatory index and C‐reactive protein concentrations during pregnancy

Shin, D., Hur, J., Cho, E. H., Chung, H. K., Shivappa, N., Wirth, M. D., Hébert, J. R. & Lee, K. W., Apr 2017, In : Nutrients. 9, 4, 351.

Research output: Contribution to journalArticle

11 Scopus citations
5 Scopus citations
2016

Computational Approaches to Accelerating Novel Medicine and Better Patient Care from Bedside to Benchtop

Sakellaropoulos, T., Hur, J., Melas, I. N., Guo, E. Y., Alexopoulos, L., Bohlooly, M. & Bai, J. P. F., 2016, Advances in Protein Chemistry and Structural Biology. Donev, R. (ed.). Academic Press Inc., p. 147-179 33 p. (Advances in Protein Chemistry and Structural Biology; vol. 102).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Expression of microRNAs in human post-mortem amyotrophic lateral sclerosis spinal cords provides insight into disease mechanisms

Figueroa-Romero, C., Hur, J., Lunn, J. S., Paez-Colasante, X., Bender, D. E., Yung, R., Sakowski, S. A. & Feldman, E. L., Mar 1 2016, In : Molecular and Cellular Neuroscience. 71, p. 34-45 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Gender-specific differences in diabetic neuropathy in BTBR ob/ob mice

O'Brien, P. D., Hur, J., Robell, N. J., Hayes, J. M., Sakowski, S. A. & Feldman, E. L., Jan 1 2016, In : Journal of Diabetes and Its Complications. 30, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse

Chella Krishnan, K., Mukundan, S., Alagarsamy, J., Hur, J., Nookala, S., Siemens, N., Svensson, M., Hyldegaard, O., Norrby-Teglund, A. & Kotb, M., Jul 2016, In : PLoS pathogens. 12, 7, e1005732.

Research output: Contribution to journalArticle

11 Scopus citations

Ignet: A centrality and INO-based web system for analyzing and visualizing literature-mined networks

Özgür, A., Hur, J., Xiang, Z., Ong, E., Radev, D. R. & He, Y., 2016, In : CEUR Workshop Proceedings. 1747

Research output: Contribution to journalConference article

Ontology-based collection, representation and analysis of drug-associated neuropathy adverse events

Guo, A., Racz, R., Hur, J., Lin, Y., Xiang, Z., Zhao, L., Rinder, J., Jiang, G., Zhu, Q. & He, Y., May 21 2016, In : Journal of Biomedical Semantics. 7, 1, 29.

Research output: Contribution to journalArticle

12 Scopus citations
3 Scopus citations

Transcriptional networks of murine diabetic peripheral neuropathy and nephropathy: common and distinct gene expression patterns

Hur, J., O’Brien, P. D., Nair, V., Hinder, L. M., McGregor, B. A., Jagadish, H. V., Kretzler, M., Brosius, F. C. & Feldman, E. L., Jun 1 2016, In : Diabetologia. 59, 6, p. 1297-1306 10 p.

Research output: Contribution to journalArticle

13 Scopus citations
2015

BTBR ob/ob mice as a novel diabetic neuropathy model: Neurological characterization and gene expression analyses

O'Brien, P. D., Hur, J., Hayes, J. M., Backus, C., Sakowski, S. A. & Feldman, E. L., Jan 1 2015, In : Neurobiology of Disease. 73, p. 348-355 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Development and application of an interaction network ontology for literature mining of vaccine-associated gene-gene interactions

Hur, J., Özgür, A., Xiang, Z. & He, Y., Jan 6 2015, In : Journal of Biomedical Semantics. 6, 1, 2.

Research output: Contribution to journalArticle

15 Scopus citations

Early gestational weight gain rate and adverse pregnancy outcomes in Korean women

Cho, E. H., Hur, J. & Lee, K. J., Oct 14 2015, In : PloS one. 10, 10, e0140376.

Research output: Contribution to journalArticle

25 Scopus citations

GLASS: A comprehensive database for experimentally validated GPCR-ligand associations

Chan, W. K. B., Zhang, H., Yang, J., Brender, J. R., Hur, J., Ozgur, A. & Zhang, Y., Jul 31 2015, In : Bioinformatics. 31, 18, p. 3035-3042 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Literature mining and ontology based analysis of host-Brucella gene-gene interaction network

Karadeniz, I., Hur, J., He, Y. & Özgür, A., 2015, In : Frontiers in Microbiology. 6, DEC, 01386.

Research output: Contribution to journalArticle

5 Scopus citations

Systems Pharmacological Analysis of Drugs Inducing Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Hur, J., Zhao, C. & Bai, J. P. F., May 18 2015, In : Chemical Research in Toxicology. 28, 5, p. 927-934 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

The metabolic syndrome and microvascular complications in a murine model of type 2 diabetes

Hur, J., Dauch, J. R., Hinder, L. M., Hayes, J. M., Backus, C., Pennathur, S., Kretzler, M., Brosius, F. C. & Feldman, E. L., Sep 2015, In : Diabetes. 64, 9, p. 3294-3304 11 p.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Drug-induced rhabdomyolysis: From systems pharmacology analysis to biochemical flux

Hur, J., Liu, Z., Tong, W., Laaksonen, R. & Bai, J. P. F., Mar 17 2014, In : Chemical Research in Toxicology. 27, 3, p. 421-432 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Fluoxetine prevents dystrophic changes in a zebrafish model of duchenne muscular dystrophy

Waugh, T. A., Horstick, E., Hur, J., Jackson, S. W., Davidson, A. E., Li, X. & Dowling, J. J., Sep 2014, In : Human Molecular Genetics. 23, 17, p. 4651-4662 12 p., ddu185.

Research output: Contribution to journalArticle

30 Scopus citations

Integrated systems pharmacology analysis of clinical drug-induced peripheral neuropathy

Hur, J., Guo, A. Y., Loh, W. Y., Feldman, E. L. & Bai, J. P. F., May 2014, In : CPT: Pharmacometrics and Systems Pharmacology. 3, 5, e114.

Research output: Contribution to journalArticle

21 Scopus citations