Junguk Hur, PhD

  • 2128 Citations
  • 22 h-Index
20042020

Research output per year

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Research Output

A 2018 workshop: Vaccine and drug ontology studies (VDOS 2018)

Hur, J., Tao, C. & He, Y., Dec 23 2019, In : BMC bioinformatics. 20, 705.

Research output: Contribution to journalReview article

Open Access

Abnormal RNA stability in amyotrophic lateral sclerosis

Tank, E. M., Figueroa-Romero, C., Hinder, L. M., Bedi, K., Archbold, H. C., Li, X., Weskamp, K., Safren, N., Paez-Colasante, X., Pacut, C., Thumma, S., Paulsen, M. T., Guo, K., Hur, J., Ljungman, M., Feldman, E. L. & Barmada, S. J., Dec 1 2018, In : Nature communications. 9, 1, 2845.

Research output: Contribution to journalArticle

22 Scopus citations

A computational platform and guide for acceleration of novel medicines and personalized medicine

Melas, I. N., Sakellaropoulos, T., Hur, J., Messinis, D., Guo, E. Y., Alexopoulos, L. G. & Bai, J. P. F., 2019, Methods in Molecular Biology. Humana Press Inc., p. 181-198 18 p. (Methods in Molecular Biology; vol. 1939).

Research output: Chapter in Book/Report/Conference proceedingChapter

Acute Biophysical Responses and Psychological Effects of Different Types of Forests in Patients With Metabolic Syndrome

Lee, K. J., Hur, J., Yang, K. S., Lee, M. K. & Lee, S. J., Apr 1 2018, In : Environment and Behavior. 50, 3, p. 298-323 26 p.

Research output: Contribution to journalArticle

5 Scopus citations

Advances in omics for informed pharmaceutical research and development in the era of systems medicine

Bai, J. P. F., Melas, I. N., Hur, J. & Guo, E., Jan 2 2018, In : Expert Opinion on Drug Discovery. 13, 1, p. 1-4 4 p.

Research output: Contribution to journalEditorial

3 Scopus citations

A graph-theoretic modeling on GO space for biological interpretation of gene clusters

Lee, S. G., Hur, J. U. & Kim, Y. S., Feb 12 2004, In : Bioinformatics. 20, 3, p. 381-388 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

A Network Pharmacology Approach for the Identification of Common Mechanisms of Drug-Induced Peripheral Neuropathy

de Anda-Jáuregui, G., McGregor, B. A., Guo, K. & Hur, J., Apr 2019, In : CPT: Pharmacometrics and Systems Pharmacology. 8, 4, p. 211-219 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation

Witt, K. L., Hsieh, J. H., Smith-Roe, S. L., Xia, M., Huang, R., Zhao, J., Auerbach, S. S., Hur, J. & Tice, R. R., Aug 2017, In : Environmental and Molecular Mutagenesis. 58, 7, p. 494-507 14 p.

Research output: Contribution to journalArticle

5 Scopus citations
3 Scopus citations

BTBR ob/ob mice as a novel diabetic neuropathy model: Neurological characterization and gene expression analyses

O'Brien, P. D., Hur, J., Hayes, J. M., Backus, C., Sakowski, S. A. & Feldman, E. L., Jan 1 2015, In : Neurobiology of Disease. 73, p. 348-355 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Central nervous system endoplasmic reticulum stress in a murine model of Type 2 diabetes

Sims-Robinson, C., Zhao, S., Hur, J. & Feldman, E. L., Aug 2012, In : Diabetologia. 55, 8, p. 2276-2284 9 p.

Research output: Contribution to journalReview article

33 Scopus citations

CIDO, a community-based ontology for coronavirus disease knowledge and data integration, sharing, and analysis

He, Y., Yu, H., Ong, E., Wang, Y., Liu, Y., Huffman, A., Huang, H. H., Beverley, J., Hur, J., Yang, X., Chen, L., Omenn, G. S., Athey, B. & Smith, B., Dec 1 2020, In : Scientific Data. 7, 1, 181.

Research output: Contribution to journalComment/debate

Open Access

Comparative RNA-Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease

Hinder, L. M., Park, M., Rumora, A. E., Hur, J., Eichinger, F., Pennathur, S., Kretzler, M., Brosius, F. C. & Feldman, E. L., Sep 2017, In : Journal of cellular and molecular medicine. 21, 9, p. 2140-2152 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Computational Approaches to Accelerating Novel Medicine and Better Patient Care from Bedside to Benchtop

Sakellaropoulos, T., Hur, J., Melas, I. N., Guo, E. Y., Alexopoulos, L., Bohlooly, M. & Bai, J. P. F., 2016, Advances in Protein Chemistry and Structural Biology. Donev, R. (ed.). Academic Press Inc., p. 147-179 33 p. (Advances in Protein Chemistry and Structural Biology; vol. 102).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Conserved Transcriptional Signatures in Human and Murine Diabetic Peripheral Neuropathy

McGregor, B. A., Eid, S., Rumora, A. E., Murdock, B., Guo, K., de Anda-Jáuregui, G., Porter, J. E., Feldman, E. L. & Hur, J., Dec 1 2018, In : Scientific reports. 8, 1, 17678.

Research output: Contribution to journalArticle

13 Scopus citations
Open Access

Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis

Paez-Colasante, X., Figueroa-Romero, C., Rumora, A. E., Hur, J., Mendelson, F. E., Hayes, J. M., Backus, C., Taubman, G. F., Heinicke, L., Walter, N. G., Barmada, S. J., Sakowski, S. A. & Feldman, E. L., May 12 2020, In : Frontiers in Cellular Neuroscience. 14, 117.

Research output: Contribution to journalArticle

Open Access

Development and application of an interaction network ontology for literature mining of vaccine-associated gene-gene interactions

Hur, J., Özgür, A., Xiang, Z. & He, Y., Jan 6 2015, In : Journal of Biomedical Semantics. 6, 1, 2.

Research output: Contribution to journalArticle

15 Scopus citations

Diabetic neuropathy: One disease or two?

Callaghan, B. C., Hur, J. & Feldman, E. L., Oct 2012, In : Current Opinion in Neurology. 25, 5, p. 536-541 6 p.

Research output: Contribution to journalReview article

86 Scopus citations

Drug-induced rhabdomyolysis: From systems pharmacology analysis to biochemical flux

Hur, J., Liu, Z., Tong, W., Laaksonen, R. & Bai, J. P. F., Mar 17 2014, In : Chemical Research in Toxicology. 27, 3, p. 421-432 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Early gestational weight gain rate and adverse pregnancy outcomes in Korean women

Cho, E. H., Hur, J. & Lee, K. J., Oct 14 2015, In : PloS one. 10, 10, e0140376.

Research output: Contribution to journalArticle

27 Scopus citations

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

Han, J., Back, S. H., Hur, J., Lin, Y. H., Gildersleeve, R., Shan, J., Yuan, C. L., Krokowski, D., Wang, S., Hatzoglou, M., Kilberg, M. S., Sartor, M. A. & Kaufman, R. J., May 2013, In : Nature Cell Biology. 15, 5, p. 481-490 10 p.

Research output: Contribution to journalArticle

716 Scopus citations

Exploration of the anti-inflammatory drug space through network pharmacology: Applications for drug repurposing

de Anda-Jáuregui, G., Guo, K., McGregor, B. A. & Hur, J., Mar 1 2018, In : Frontiers in Physiology. 9, MAR, 151.

Research output: Contribution to journalArticle

7 Scopus citations

Expression of microRNAs in human post-mortem amyotrophic lateral sclerosis spinal cords provides insight into disease mechanisms

Figueroa-Romero, C., Hur, J., Lunn, J. S., Paez-Colasante, X., Bender, D. E., Yung, R., Sakowski, S. A. & Feldman, E. L., Mar 1 2016, In : Molecular and Cellular Neuroscience. 71, p. 34-45 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Fluoxetine prevents dystrophic changes in a zebrafish model of duchenne muscular dystrophy

Waugh, T. A., Horstick, E., Hur, J., Jackson, S. W., Davidson, A. E., Li, X. & Dowling, J. J., Sep 2014, In : Human Molecular Genetics. 23, 17, p. 4651-4662 12 p., ddu185.

Research output: Contribution to journalArticle

31 Scopus citations

Gender-specific differences in diabetic neuropathy in BTBR ob/ob mice

O'Brien, P. D., Hur, J., Robell, N. J., Hayes, J. M., Sakowski, S. A. & Feldman, E. L., Jan 1 2016, In : Journal of Diabetes and Its Complications. 30, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse

Chella Krishnan, K., Mukundan, S., Alagarsamy, J., Hur, J., Nookala, S., Siemens, N., Svensson, M., Hyldegaard, O., Norrby-Teglund, A. & Kotb, M., Jul 2016, In : PLoS pathogens. 12, 7, e1005732.

Research output: Contribution to journalArticle

11 Scopus citations

Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus

Guo, K., Elzinga, S., Eid, S., Figueroa-Romero, C., Hinder, L. M., Pacut, C., Feldman, E. L. & Hur, J., Aug 3 2019, In : Epigenetics. 14, 8, p. 766-779 14 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy

Guo, K., Eid, S. A., Elzinga, S. E., Pacut, C., Feldman, E. L. & Hur, J., Aug 12 2020, In : Clinical Epigenetics. 12, 1, p. 123 1 p.

Research output: Contribution to journalArticle

Open Access

GLASS: A comprehensive database for experimentally validated GPCR-ligand associations

Chan, W. K. B., Zhang, H., Yang, J., Brender, J. R., Hur, J., Ozgur, A. & Zhang, Y., Jul 31 2015, In : Bioinformatics. 31, 18, p. 3035-3042 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Identification of Casiopeina II-gly secondary targets through a systems pharmacology approach

de Anda-Jáuregui, G., Espinal-Enríquez, J., Hur, J., Alcalá-Corona, S. A., Ruiz-Azuara, L. & Hernández-Lemus, E., Feb 2019, In : Computational Biology and Chemistry. 78, p. 127-132 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Identification of Epigenetically Altered Genes in Sporadic Amyotrophic Lateral Sclerosis

Figueroa-Romero, C., Hur, J., Bender, D. E., Delaney, C. E., Cataldo, M. D., Smith, A. L., Yung, R., Ruden, D. M., Callaghan, B. C. & Feldman, E. L., Dec 29 2012, In : PloS one. 7, 12, e52672.

Research output: Contribution to journalArticle

74 Scopus citations

Identification of factors associated with sural nerve regeneration and degeneration in diabetic neuropathy

Hur, J., Sullivan, K. A., Callaghan, B. C., Pop-Busui, R. & Feldman, E. L., Dec 2013, In : Diabetes Care. 36, 12, p. 4043-4049 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining

Hur, J., Özgür, A., Xiang, Z. & He, Y., Dec 20 2012, In : Journal of Biomedical Semantics. 3, 1, 18.

Research output: Contribution to journalArticle

22 Scopus citations

Ignet: A centrality and INO-based web system for analyzing and visualizing literature-mined networks

Özgür, A., Hur, J., Xiang, Z., Ong, E., Radev, D. R. & He, Y., 2016, In : CEUR Workshop Proceedings. 1747

Research output: Contribution to journalConference article

Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes

O’Brien, P. D., Guo, K., Eid, S. A., Rumora, A. E., Hinder, L. M., Hayes, J. M., Mendelson, F. E., Hur, J. & Feldman, E. L., 2020, In : DMM Disease Models and Mechanisms. 13, 2, dmm042101.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Integrated systems pharmacology analysis of clinical drug-induced peripheral neuropathy

Hur, J., Guo, A. Y., Loh, W. Y., Feldman, E. L. & Bai, J. P. F., May 2014, In : CPT: Pharmacometrics and Systems Pharmacology. 3, 5, e114.

Research output: Contribution to journalArticle

21 Scopus citations

Intraspinal neural stem cell transplantation in amyotrophic lateral sclerosis: Phase 1 trial outcomes

Feldman, E. L., Boulis, N. M., Hur, J., Johe, K., Rutkove, S. B., Federici, T., Polak, M., Bordeau, J., Sakowski, S. A. & Glass, J. D., Mar 2014, In : Annals of Neurology. 75, 3, p. 363-373 11 p.

Research output: Contribution to journalArticle

115 Scopus citations

Literature-based discovery of diabetes- and ROS-related targets

Hur, J., Sullivan, K. A., Schuyler, A. D., Hong, Y., Pande, M., States, D. J., Jagadish, H. V. & Feldman, E. L., 2010, In : BMC Medical Genomics. 3, 49.

Research output: Contribution to journalArticle

25 Scopus citations

Literature mining and ontology based analysis of host-Brucella gene-gene interaction network

Karadeniz, I., Hur, J., He, Y. & Özgür, A., 2015, In : Frontiers in Microbiology. 6, DEC, 01386.

Research output: Contribution to journalArticle

5 Scopus citations

Machine learning-based identification and rule-based normalization of adverse drug reactions in drug labels

Tiftikci, M., Özgür, A., He, Y. & Hur, J., Dec 23 2019, In : BMC bioinformatics. 20, 707.

Research output: Contribution to journalArticle

Open Access

Network-based assessment of adverse drug reaction risk in polypharmacy using high-throughput screening data

de Anda-Jáuregui, G., Guo, K. & Hur, J., Jan 2 2019, In : International journal of molecular sciences. 20, 2, 386.

Research output: Contribution to journalArticle

1 Scopus citations

Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association network

Hur, J., Xiang, Z., Feldman, E. L. & He, Y., Aug 26 2011, In : BMC Immunology. 12, 49.

Research output: Contribution to journalArticle

27 Scopus citations

Ontology-based collection, representation and analysis of drug-associated neuropathy adverse events

Guo, A., Racz, R., Hur, J., Lin, Y., Xiang, Z., Zhao, L., Rinder, J., Jiang, G., Zhu, Q. & He, Y., May 21 2016, In : Journal of Biomedical Semantics. 7, 1, 29.

Research output: Contribution to journalArticle

12 Scopus citations
3 Scopus citations

Ontology-based literature mining of E. coli vaccine-associated gene interaction networks

Hur, J., Özgür, A. & He, Y., Mar 14 2017, In : Journal of Biomedical Semantics. 8, 1, 12.

Research output: Contribution to journalArticle

5 Scopus citations

Oxidative stress and successful antioxidant treatment in models of RYR1-related myopathy

Dowling, J. J., Arbogast, S., Hur, J., Nelson, D. D., McEvoy, A., Waugh, T., Marty, I., Lunardi, J., Brooks, S. V., Kuwada, J. Y. & Ferreiro, A., Apr 2012, In : Brain. 135, 4, p. 1115-1127 13 p.

Research output: Contribution to journalArticle

71 Scopus citations

Pathway crosstalk perturbation network modeling for identification of connectivity changes induced by diabetic neuropathy and pioglitazone

de Anda-Jáuregui, G., Guo, K., McGregor, B. A., Feldman, E. L. & Hur, J., Jan 7 2019, In : BMC systems biology. 13, 1, 1.

Research output: Contribution to journalArticle

4 Scopus citations

Prediction of gestational diabetes mellitus by unconjugated estriol levels in maternal serum

Hur, J., Cho, E. H., Baek, K. H. & Lee, K. J., Feb 7 2017, In : International Journal of Medical Sciences. 14, 2, p. 123-127 5 p.

Research output: Contribution to journalArticle

8 Scopus citations