Junguk Hur, PhD

  • 2166 Citations
  • 22 h-Index
20042020

Research output per year

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Research Output

Article

Abnormal RNA stability in amyotrophic lateral sclerosis

Tank, E. M., Figueroa-Romero, C., Hinder, L. M., Bedi, K., Archbold, H. C., Li, X., Weskamp, K., Safren, N., Paez-Colasante, X., Pacut, C., Thumma, S., Paulsen, M. T., Guo, K., Hur, J., Ljungman, M., Feldman, E. L. & Barmada, S. J., Dec 1 2018, In : Nature communications. 9, 1, 2845.

Research output: Contribution to journalArticle

23 Scopus citations

Acute Biophysical Responses and Psychological Effects of Different Types of Forests in Patients With Metabolic Syndrome

Lee, K. J., Hur, J., Yang, K. S., Lee, M. K. & Lee, S. J., Apr 1 2018, In : Environment and Behavior. 50, 3, p. 298-323 26 p.

Research output: Contribution to journalArticle

6 Scopus citations

A graph-theoretic modeling on GO space for biological interpretation of gene clusters

Lee, S. G., Hur, J. U. & Kim, Y. S., Feb 12 2004, In : Bioinformatics. 20, 3, p. 381-388 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

A Network Pharmacology Approach for the Identification of Common Mechanisms of Drug-Induced Peripheral Neuropathy

de Anda-Jáuregui, G., McGregor, B. A., Guo, K. & Hur, J., Apr 2019, In : CPT: Pharmacometrics and Systems Pharmacology. 8, 4, p. 211-219 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation

Witt, K. L., Hsieh, J. H., Smith-Roe, S. L., Xia, M., Huang, R., Zhao, J., Auerbach, S. S., Hur, J. & Tice, R. R., Aug 2017, In : Environmental and Molecular Mutagenesis. 58, 7, p. 494-507 14 p.

Research output: Contribution to journalArticle

5 Scopus citations
3 Scopus citations

BTBR ob/ob mice as a novel diabetic neuropathy model: Neurological characterization and gene expression analyses

O'Brien, P. D., Hur, J., Hayes, J. M., Backus, C., Sakowski, S. A. & Feldman, E. L., Jan 1 2015, In : Neurobiology of Disease. 73, p. 348-355 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Comparative RNA-Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease

Hinder, L. M., Park, M., Rumora, A. E., Hur, J., Eichinger, F., Pennathur, S., Kretzler, M., Brosius, F. C. & Feldman, E. L., Sep 2017, In : Journal of cellular and molecular medicine. 21, 9, p. 2140-2152 13 p.

Research output: Contribution to journalArticle

21 Scopus citations

Conserved Transcriptional Signatures in Human and Murine Diabetic Peripheral Neuropathy

McGregor, B. A., Eid, S., Rumora, A. E., Murdock, B., Guo, K., de Anda-Jáuregui, G., Porter, J. E., Feldman, E. L. & Hur, J., Dec 1 2018, In : Scientific reports. 8, 1, 17678.

Research output: Contribution to journalArticle

13 Scopus citations

Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis

Paez-Colasante, X., Figueroa-Romero, C., Rumora, A. E., Hur, J., Mendelson, F. E., Hayes, J. M., Backus, C., Taubman, G. F., Heinicke, L., Walter, N. G., Barmada, S. J., Sakowski, S. A. & Feldman, E. L., May 12 2020, In : Frontiers in Cellular Neuroscience. 14, 117.

Research output: Contribution to journalArticle

Open Access

Development and application of an interaction network ontology for literature mining of vaccine-associated gene-gene interactions

Hur, J., Özgür, A., Xiang, Z. & He, Y., Jan 6 2015, In : Journal of Biomedical Semantics. 6, 1, 2.

Research output: Contribution to journalArticle

15 Scopus citations

Drug-induced rhabdomyolysis: From systems pharmacology analysis to biochemical flux

Hur, J., Liu, Z., Tong, W., Laaksonen, R. & Bai, J. P. F., Mar 17 2014, In : Chemical Research in Toxicology. 27, 3, p. 421-432 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Early gestational weight gain rate and adverse pregnancy outcomes in Korean women

Cho, E. H., Hur, J. & Lee, K. J., Oct 14 2015, In : PloS one. 10, 10, e0140376.

Research output: Contribution to journalArticle

28 Scopus citations

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

Han, J., Back, S. H., Hur, J., Lin, Y. H., Gildersleeve, R., Shan, J., Yuan, C. L., Krokowski, D., Wang, S., Hatzoglou, M., Kilberg, M. S., Sartor, M. A. & Kaufman, R. J., May 2013, In : Nature Cell Biology. 15, 5, p. 481-490 10 p.

Research output: Contribution to journalArticle

725 Scopus citations

Exploration of the anti-inflammatory drug space through network pharmacology: Applications for drug repurposing

de Anda-Jáuregui, G., Guo, K., McGregor, B. A. & Hur, J., Mar 1 2018, In : Frontiers in Physiology. 9, MAR, 151.

Research output: Contribution to journalArticle

7 Scopus citations

Expression of microRNAs in human post-mortem amyotrophic lateral sclerosis spinal cords provides insight into disease mechanisms

Figueroa-Romero, C., Hur, J., Lunn, J. S., Paez-Colasante, X., Bender, D. E., Yung, R., Sakowski, S. A. & Feldman, E. L., Mar 1 2016, In : Molecular and Cellular Neuroscience. 71, p. 34-45 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Fluoxetine prevents dystrophic changes in a zebrafish model of duchenne muscular dystrophy

Waugh, T. A., Horstick, E., Hur, J., Jackson, S. W., Davidson, A. E., Li, X. & Dowling, J. J., Sep 2014, In : Human Molecular Genetics. 23, 17, p. 4651-4662 12 p., ddu185.

Research output: Contribution to journalArticle

32 Scopus citations

Gender-specific differences in diabetic neuropathy in BTBR ob/ob mice

O'Brien, P. D., Hur, J., Robell, N. J., Hayes, J. M., Sakowski, S. A. & Feldman, E. L., Jan 1 2016, In : Journal of Diabetes and Its Complications. 30, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse

Chella Krishnan, K., Mukundan, S., Alagarsamy, J., Hur, J., Nookala, S., Siemens, N., Svensson, M., Hyldegaard, O., Norrby-Teglund, A. & Kotb, M., Jul 2016, In : PLoS pathogens. 12, 7, e1005732.

Research output: Contribution to journalArticle

11 Scopus citations

Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus

Guo, K., Elzinga, S., Eid, S., Figueroa-Romero, C., Hinder, L. M., Pacut, C., Feldman, E. L. & Hur, J., Aug 3 2019, In : Epigenetics. 14, 8, p. 766-779 14 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy

Guo, K., Eid, S. A., Elzinga, S. E., Pacut, C., Feldman, E. L. & Hur, J., Aug 12 2020, In : Clinical Epigenetics. 12, 1, p. 123 1 p.

Research output: Contribution to journalArticle

Open Access

GLASS: A comprehensive database for experimentally validated GPCR-ligand associations

Chan, W. K. B., Zhang, H., Yang, J., Brender, J. R., Hur, J., Ozgur, A. & Zhang, Y., Jul 31 2015, In : Bioinformatics. 31, 18, p. 3035-3042 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Identification of Casiopeina II-gly secondary targets through a systems pharmacology approach

de Anda-Jáuregui, G., Espinal-Enríquez, J., Hur, J., Alcalá-Corona, S. A., Ruiz-Azuara, L. & Hernández-Lemus, E., Feb 2019, In : Computational Biology and Chemistry. 78, p. 127-132 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Identification of Epigenetically Altered Genes in Sporadic Amyotrophic Lateral Sclerosis

Figueroa-Romero, C., Hur, J., Bender, D. E., Delaney, C. E., Cataldo, M. D., Smith, A. L., Yung, R., Ruden, D. M., Callaghan, B. C. & Feldman, E. L., Dec 29 2012, In : PloS one. 7, 12, e52672.

Research output: Contribution to journalArticle

75 Scopus citations

Identification of factors associated with sural nerve regeneration and degeneration in diabetic neuropathy

Hur, J., Sullivan, K. A., Callaghan, B. C., Pop-Busui, R. & Feldman, E. L., Dec 2013, In : Diabetes Care. 36, 12, p. 4043-4049 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining

Hur, J., Özgür, A., Xiang, Z. & He, Y., Dec 20 2012, In : Journal of Biomedical Semantics. 3, 1, 18.

Research output: Contribution to journalArticle

22 Scopus citations

Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes

O’Brien, P. D., Guo, K., Eid, S. A., Rumora, A. E., Hinder, L. M., Hayes, J. M., Mendelson, F. E., Hur, J. & Feldman, E. L., 2020, In : DMM Disease Models and Mechanisms. 13, 2, dmm042101.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Integrated systems pharmacology analysis of clinical drug-induced peripheral neuropathy

Hur, J., Guo, A. Y., Loh, W. Y., Feldman, E. L. & Bai, J. P. F., May 2014, In : CPT: Pharmacometrics and Systems Pharmacology. 3, 5, e114.

Research output: Contribution to journalArticle

21 Scopus citations

Intraspinal neural stem cell transplantation in amyotrophic lateral sclerosis: Phase 1 trial outcomes

Feldman, E. L., Boulis, N. M., Hur, J., Johe, K., Rutkove, S. B., Federici, T., Polak, M., Bordeau, J., Sakowski, S. A. & Glass, J. D., Mar 2014, In : Annals of Neurology. 75, 3, p. 363-373 11 p.

Research output: Contribution to journalArticle

119 Scopus citations

Literature-based discovery of diabetes- and ROS-related targets

Hur, J., Sullivan, K. A., Schuyler, A. D., Hong, Y., Pande, M., States, D. J., Jagadish, H. V. & Feldman, E. L., 2010, In : BMC Medical Genomics. 3, 49.

Research output: Contribution to journalArticle

25 Scopus citations

Literature mining and ontology based analysis of host-Brucella gene-gene interaction network

Karadeniz, I., Hur, J., He, Y. & Özgür, A., 2015, In : Frontiers in Microbiology. 6, DEC, 01386.

Research output: Contribution to journalArticle

5 Scopus citations

Machine learning-based identification and rule-based normalization of adverse drug reactions in drug labels

Tiftikci, M., Özgür, A., He, Y. & Hur, J., Dec 23 2019, In : BMC bioinformatics. 20, 707.

Research output: Contribution to journalArticle

Open Access

Network-based assessment of adverse drug reaction risk in polypharmacy using high-throughput screening data

de Anda-Jáuregui, G., Guo, K. & Hur, J., Jan 2 2019, In : International journal of molecular sciences. 20, 2, 386.

Research output: Contribution to journalArticle

1 Scopus citations

Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association network

Hur, J., Xiang, Z., Feldman, E. L. & He, Y., Aug 26 2011, In : BMC Immunology. 12, 49.

Research output: Contribution to journalArticle

27 Scopus citations

Ontology-based collection, representation and analysis of drug-associated neuropathy adverse events

Guo, A., Racz, R., Hur, J., Lin, Y., Xiang, Z., Zhao, L., Rinder, J., Jiang, G., Zhu, Q. & He, Y., May 21 2016, In : Journal of Biomedical Semantics. 7, 1, 29.

Research output: Contribution to journalArticle

12 Scopus citations
3 Scopus citations

Ontology-based literature mining of E. coli vaccine-associated gene interaction networks

Hur, J., Özgür, A. & He, Y., Mar 14 2017, In : Journal of Biomedical Semantics. 8, 1, 12.

Research output: Contribution to journalArticle

5 Scopus citations

Oxidative stress and successful antioxidant treatment in models of RYR1-related myopathy

Dowling, J. J., Arbogast, S., Hur, J., Nelson, D. D., McEvoy, A., Waugh, T., Marty, I., Lunardi, J., Brooks, S. V., Kuwada, J. Y. & Ferreiro, A., Apr 2012, In : Brain. 135, 4, p. 1115-1127 13 p.

Research output: Contribution to journalArticle

72 Scopus citations

Pathway crosstalk perturbation network modeling for identification of connectivity changes induced by diabetic neuropathy and pioglitazone

de Anda-Jáuregui, G., Guo, K., McGregor, B. A., Feldman, E. L. & Hur, J., Jan 7 2019, In : BMC systems biology. 13, 1, 1.

Research output: Contribution to journalArticle

4 Scopus citations

Prediction of gestational diabetes mellitus by unconjugated estriol levels in maternal serum

Hur, J., Cho, E. H., Baek, K. H. & Lee, K. J., Feb 7 2017, In : International Journal of Medical Sciences. 14, 2, p. 123-127 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Pre‐pregnancy body mass index is associated with dietary inflammatory index and C‐reactive protein concentrations during pregnancy

Shin, D., Hur, J., Cho, E. H., Chung, H. K., Shivappa, N., Wirth, M. D., Hébert, J. R. & Lee, K. W., Apr 2017, In : Nutrients. 9, 4, 351.

Research output: Contribution to journalArticle

11 Scopus citations
6 Scopus citations

PubChemSR: A search and retrieval tool for PubChem

Hur, J. & Wild, D. J., 2008, In : Chemistry Central Journal. 2, 1, 11.

Research output: Contribution to journalArticle

15 Scopus citations

SciMiner: Web-based literature mining tool for target identification and functional enrichment analysis

Hur, J., Schuyler, A. D., States, D. J. & Feldman, E. L., Mar 2009, In : Bioinformatics. 25, 6, p. 838-840 3 p.

Research output: Contribution to journalArticle

62 Scopus citations

Stem cell technology for neurodegenerative diseases

Lunn, J. S., Sakowski, S. A., Hur, J. & Feldman, E. L., Sep 2011, In : Annals of Neurology. 70, 3, p. 353-361 9 p.

Research output: Contribution to journalArticle

139 Scopus citations

Systems Pharmacological Analysis of Drugs Inducing Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Hur, J., Zhao, C. & Bai, J. P. F., May 18 2015, In : Chemical Research in Toxicology. 28, 5, p. 927-934 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice

Figueroa-Romero, C., Guo, K., Murdock, B. J., Paez-Colasante, X., Bassis, C. M., Mikhail, K. A., Raue, K. D., Evans, M. C., Taubman, G. F., McDermott, A. J., O'Brien, P. D., Savelieff, M. G., Hur, J. & Feldman, E. L., 2020, In : DMM Disease Models and Mechanisms. 13, 2, dmm041947.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

The identification of gene expression profiles associated with progression of human diabetic neuropathy

Hur, J., Sullivan, K. A., Pande, M., Hong, Y., Sima, A. A. F., Jagadish, H. V., Kretzler, M. & Feldman, E. L., Nov 2011, In : Brain. 134, 11, p. 3222-3235 14 p.

Research output: Contribution to journalArticle

72 Scopus citations

The metabolic syndrome and microvascular complications in a murine model of type 2 diabetes

Hur, J., Dauch, J. R., Hinder, L. M., Hayes, J. M., Backus, C., Pennathur, S., Kretzler, M., Brosius, F. C. & Feldman, E. L., Sep 2015, In : Diabetes. 64, 9, p. 3294-3304 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

The Role of Oxidative Stress in Nervous System Aging

Sims-Robinson, C., Hur, J., Hayes, J. M., Dauch, J. R., Keller, P. J., Brooks, S. V. & Feldman, E. L., Jul 2 2013, In : PloS one. 8, 7, e68011.

Research output: Contribution to journalArticle

28 Scopus citations