• 9241 Citations
  • 42 h-Index
1980 …2020

Research output per year

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Research Output

2020

Amiodarone Alters Cholesterol Biosynthesis through Tissue-Dependent Inhibition of Emopamil Binding Protein and Dehydrocholesterol Reductase 24

Allen, L. B., Genaro-Mattos, T. C., Anderson, A., Porter, N. A., Mirnics, K. & Korade, Z., May 20 2020, In : ACS Chemical Neuroscience. 11, 10, p. 1413-1423 11 p.

Research output: Contribution to journalArticle

2019

Cholesterol Biosynthesis and Uptake in Developing Neurons

Genaro-Mattos, T. C., Anderson, A., Allen, L. B., Korade, Z. & Mirnics, K., Aug 21 2019, In : ACS Chemical Neuroscience. 10, 8, p. 3671-3681 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Desmosterolosis and desmosterol homeostasis in the developing mouse brain

Allen, L. B., Genaro-Mattos, T. C., Porter, N. A., Mirnics, K. & Korade, Z., Sep 1 2019, In : Journal of Inherited Metabolic Disease. 42, 5, p. 934-943 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Maternal aripiprazole exposure interacts with 7-dehydrocholesterol reductase mutations and alters embryonic neurodevelopment

Genaro-Mattos, T. C., Allen, L. B., Anderson, A., Tallman, K. A., Porter, N. A., Korade, Z. & Mirnics, K., Apr 1 2019, In : Molecular Psychiatry. 24, 4, p. 491-500 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Sex modifies placental gene expression in response to metabolic and inflammatory stress

Barke, T. L., Money, K. M., Du, L., Serezani, A., Gannon, M., Mirnics, K. & Aronoff, D. M., Mar 2019, In : Placenta. 78, p. 1-9 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Subcellular localization of sterol biosynthesis enzymes

Koczok, K., Gurumurthy, C. B., Balogh, I., Korade, Z. & Mirnics, K., Feb 15 2019, In : Journal of Molecular Histology. 50, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

2018
7 Scopus citations

Gestational diabetes exacerbates maternal immune activation effects in the developing brain

Money, K. M., Barke, T. L., Serezani, A., Gannon, M., Garbett, K. A., Aronoff, D. M. & Mirnics, K., Sep 1 2018, In : Molecular Psychiatry. 23, 9

Research output: Contribution to journalArticle

4 Scopus citations

Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex

Schwede, M., Nagpal, S., Gandal, M. J., Parikshak, N. N., Mirnics, K., Geschwind, D. H. & Morrow, E. M., Jun 1 2018, In : Journal of Neurodevelopmental Disorders. 10, 1, 18.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Connecting the Dots

Arikkath, J. & Mirnics, K., Mar 15 2017, In : Biological Psychiatry. 81, 6, p. 463-464 2 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Maternal deprivation alters expression of neural maturation gene tbr1 in the amygdala paralaminar nucleus in infant female macaques

de Campo, D. M., Cameron, J. L., Miano, J. M., Lewis, D. A., Mirnics, K. & Fudge, J. L., Mar 1 2017, In : Developmental Psychobiology. 59, 2, p. 235-249 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Vulnerability of DHCR7 +/- mutation carriers to aripiprazole and trazodone exposure

Korade, Z., Genaro-Mattos, T. C., Tallman, K. A., Liu, W., Garbett, K. A., Koczok, K., Balogh, I., Mirnics, K. & Porter, N. A., 2017, In : Journal of Lipid Research. 58, 11, p. 2139-2146 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

An altered peripheral IL6 response in major depressive disorder

Money, K. M., Olah, Z., Korade, Z., Garbett, K. A., Shelton, R. C. & Mirnics, K., May 1 2016, In : Neurobiology of Disease. 89, p. 46-54 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research

Krystal, J. H., Abi-Dargham, A., Akbarian, S., Arnsten, A. F. T., Barch, D. M., Bearden, C. E., Braff, D. L., Brown, E. S., Bullmore, E. T., Carlezon, W. A., Carter, C. S., Cook, E. H., Daskalakis, Z. J., DiLeone, R. J., Duman, R. S., Grace, A. A., Hariri, A. R., Harrison, P. J., Hiroi, N., Kenny, P. J. & 45 others, Kleinman, J. E., Krystal, A. D., Lewis, D. A., Lipska, B. K., Marder, S. R., Mason, G. F., Mathalon, D. H., McClung, C. A., McDougle, C. J., McIntosh, A. M., McMahon, F. J., Mirnics, K., Monteggia, L. M., Narendran, R., Nestler, E. J., Neumeister, A., O'Donovan, M. C., Öngür, D., Pariante, C. M., Paulus, M. P., Pearlson, G., Phillips, M. L., Pine, D. S., Pizzagalli, D. A., Pletnikov, M. V., Ragland, J. D., Rapoport, J. L., Ressler, K. J., Russo, S. J., Sanacora, G., Sawa, A., Schatzberg, A. F., Shaham, Y., Shamay-Tsoory, S. G., Sklar, P., State, M. W., Stein, M. B., Strakowski, S. M., Taylor, S. F., Turecki, G., Turetsky, B. I., Weissman, M. M., Zachariou, V., Zarate, C. A. & Zubieta, J. K., Jul 15 2016, In : Biological Psychiatry. 80, 2, p. 84-86 3 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Human dermal fibroblasts in psychiatry research

Kálmán, S., Garbett, K. A., Janka, Z. & Mirnics, K., Apr 21 2016, In : Neuroscience. 320, p. 105-121 17 p.

Research output: Contribution to journalReview article

10 Scopus citations

Inhibitors of 7-Dehydrocholesterol Reductase: Screening of a Collection of Pharmacologically Active Compounds in Neuro2a Cells

Kim, H. Y. H., Korade, Z., Tallman, K. A., Liu, W., Weaver, C. D., Mirnics, K. & Porter, N. A., May 16 2016, In : Chemical Research in Toxicology. 29, 5, p. 892-900 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex

Mitchell, A. C., Javidfar, B., Bicks, L. K., Neve, R., Garbett, K., Lander, S. S., Mirnics, K., Morishita, H., Wood, M. A., Jiang, Y., Gaisler-Salomon, I. & Akbarian, S., Sep 6 2016, In : Nature communications. 7, 12743.

Research output: Contribution to journalArticle

9 Scopus citations

The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts

Korade, Z., Kim, H. Y. H., Tallman, K. A., Liu, W., Koczok, K., Balogh, I., Xu, L., Mirnics, K. & Porter, N. A., Feb 11 2016, In : Journal of Medicinal Chemistry. 59, 3, p. 1102-1115 14 p.

Research output: Contribution to journalArticle

22 Scopus citations
2015

Coordinated messenger RNA/microRNA changes in fibroblasts of patients with major depression

Garbett, K. A., Vereczkei, A., Kálmán, S., Brown, J. A., Taylor, W. D., Faludi, G., Korade, Ž., Shelton, R. C. & Mirnics, K., Feb 1 2015, In : Biological Psychiatry. 77, 3, p. 256-265 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case-control sample of schizophrenia

Ingason, A., Giegling, I., Hartmann, A. M., Genius, J., Konte, B., Friedl, M., Ripke, S., Sullivan, P. F., St Clair, D., Collier, D. A., O'Donovan, M. C., Mirnics, K. & Rujescu, D., Oct 27 2015, In : Translational Psychiatry. 5, 10, A151.

Research output: Contribution to journalArticle

17 Scopus citations

Fibroblasts from patients with major depressive disorder show distinct transcriptional response to metabolic stressors

Garbett, K. A., Vereczkei, A., Kálmán, S., Wang, L., Korade, Z., Shelton, R. C. & Mirnics, K., 2015, In : Translational Psychiatry. 5, 3, A523.

Research output: Contribution to journalArticle

14 Scopus citations

Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes

Brown, J. A., Ramikie, T. S., Schmidt, M. J., Báldi, R., Garbett, K., Everheart, M. G., Warren, L. E., Gellért, L., Horváth, S., Patel, S. & Mirnics, K., Dec 1 2015, In : Molecular Psychiatry. 20, 12, p. 1499-1507 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Neurodevelopment, GABA system dysfunction, and schizophrenia

Schmidt, M. J. & Mirnics, K., Jan 1 2015, In : Neuropsychopharmacology. 40, 1, p. 190-206 17 p.

Research output: Contribution to journalReview article

79 Scopus citations

Schizophrenia as a disorder of molecular pathways

Horváth, S. & Mirnics, K., Jan 1 2015, In : Biological Psychiatry. 77, 1, p. 22-28 7 p.

Research output: Contribution to journalReview article

50 Scopus citations

Transcriptional maturation of the mouse auditory forebrain

Hackett, T. A., Guo, Y., Clause, A., Hackett, N. J., Garbett, K., Zhang, P., Polley, D. B. & Mirnics, K., Aug 14 2015, In : BMC genomics. 16, 1, 606.

Research output: Contribution to journalArticle

11 Scopus citations
2014

Antioxidant supplementation ameliorates molecular deficits in smith-lemli-opitz syndrome

Korade, Z., Xu, L., Harrison, F. E., Ahsen, R., Hart, S. E., Folkes, O. M., Mirnics, K. & Porter, N. A., Feb 1 2014, In : Biological Psychiatry. 75, 3, p. 215-222 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Clues from the cloud

Horváth, S. & Mirnics, K., Jul 1 2014, In : American Journal of Psychiatry. 171, 7, p. 705-708 4 p.

Research output: Contribution to journalEditorial

Genes for endosomal NHE6 and NHE9 are misregulated in autism brains

Schwede, M., Garbett, K., Mirnics, K., Geschwind, D. H. & Morrow, E. M., Mar 2014, In : Molecular Psychiatry. 19, 3, p. 277-279 3 p.

Research output: Contribution to journalLetter

36 Scopus citations

Hippocampal immunostaining of CCK-GAD1 transgenic mice

Schmidt, M. J., Horvath, S., Ebert, P., Norris, J. L., Seeley, E. H., Brown, J., Gellert, L., Everheart, M., Garbett, K. A., Grice, T. W., Caprioli, R. M. & Mirnics, K., May 2014, In : Molecular Psychiatry. 19, 5, 1 p.

Research output: Contribution to journalComment/debate

Immune system disturbances in schizophrenia

Horváth, S. & Mirnics, K., Feb 15 2014, In : Biological Psychiatry. 75, 4, p. 316-323 8 p.

Research output: Contribution to journalReview article

84 Scopus citations

Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia

Brown, J. A., Sherrod, S. D., Goodwin, C. R., Brewer, B., Yang, L., Garbett, K. A., Li, D., McLean, J. A., Wikswo, J. P. & Mirnics, K., Nov 6 2014, In : Journal of Neuroinflammation. 11, 1, 183.

Research output: Contribution to journalArticle

18 Scopus citations

Metabolic stress-induced microRNA and mRNA expression profiles of human fibroblasts

Kálmán, S., Garbett, K. A., Vereczkei, A., Shelton, R. C., Korade, Ž. & Mirnics, K., Jan 15 2014, In : Experimental Cell Research. 320, 2, p. 343-353 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Modulation of behavioral networks by selective interneuronal inactivation

Schmidt, M. J., Horvath, S., Ebert, P., Norris, J. L., Seeley, E. H., Brown, J., Gellert, L., Everheart, M., Garbett, K. A., Grice, T. W., Caprioli, R. M. & Mirnics, K., May 2014, In : Molecular Psychiatry. 19, 5, p. 580-587 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Programmed to be Humanα

Korade, Ž. & Mirnics, K., Jan 22 2014, In : Neuron. 81, 2, p. 224-226 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations

The genome in three dimensions: A new frontier in human brain research

Mitchell, A. C., Bharadwaj, R., Whittle, C., Krueger, W., Mirnics, K., Hurd, Y., Rasmussen, T. & Akbarian, S., Jun 15 2014, In : Biological Psychiatry. 75, 12, p. 961-969 9 p.

Research output: Contribution to journalReview article

36 Scopus citations

The role of cannabinoid 1 receptor expressing interneurons in behavior

Brown, J. A., Horváth, S., Garbett, K. A., Schmidt, M. J., Everheart, M., Gellért, L., Ebert, P. & Mirnics, K., Mar 2014, In : Neurobiology of Disease. 63, p. 210-221 12 p.

Research output: Contribution to journalArticle

17 Scopus citations
2013

Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia

Bharadwa, R., Jiang, Y., Mao, W., Jakovcevski, M., Dincer, A., Krueger, W., Garbett, K., Whittle, C., Tushir, J. S., Liu, J., Sequeira, A., Vawter, M. P., Gardner, P. D., Casaccia, P., Rasmussen, T., Bunney, W. E., Mirnics, K., Futai, K. & Akbarian, S., 2013, In : Journal of Neuroscience. 33, 29, p. 11839-11851 13 p.

Research output: Contribution to journalArticle

43 Scopus citations

Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome

Korade, Z., Xu, L., Mirnics, K. & Porter, N. A., Jan 2013, In : Journal of Inherited Metabolic Disease. 36, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Lost their ways?

Brown, J. A. & Mirnics, K., Sep 15 2013, In : Biological Psychiatry. 74, 6, p. 398-399 2 p.

Research output: Contribution to journalComment/debate

Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells

Xu, L., Korade, Z., Rosado, D. A., Mirnics, K. & Porter, N. A., Apr 2013, In : Journal of Lipid Research. 54, 4, p. 1135-1143 9 p.

Research output: Contribution to journalArticle

32 Scopus citations
2012

A role for presenilins in autophagy revisited: Normal acidification of lysosomes in cells lacking PSEN1 and PSEN2

Zhang, X., Garbett, K., Veeraraghavalu, K., Wilburn, B., Gilmore, R., Mirnics, K. & Sisodia, S. S., Jun 20 2012, In : Journal of Neuroscience. 32, 25, p. 8633-8648 16 p.

Research output: Contribution to journalArticle

67 Scopus citations

Beszámoló a Környey Társaság 2011. évi tudományos ülésérocombining double acute accentl 2. rész

Translated title of the contribution: Account on the scientific meeting of Környey Society in 2011. Part 2Tcimás, D., Szatmár, H., Károly, M., József, J., Peter, B., Zsolt, H. & Andrea, M., Jan 30 2012, In : Ideggyogyaszati Szemle. 65, 1-2, p. 49-59 11 p.

Research output: Contribution to journalReview article

DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemli-Opitz syndrome model

Xu, L., Mirnics, K., Bowman, A. B., Liu, W., Da, J., Porter, N. A. & Korade, Z., Mar 2012, In : Neurobiology of Disease. 45, 3, p. 923-929 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Effects of maternal immune activation on gene expression patterns in the fetal brain

Garbett, K. A., Hsiao, E. Y., Kálmán, S., Patterson, P. H. & Mirnics, K., 2012, In : Translational Psychiatry. 2, e98.

Research output: Contribution to journalArticle

94 Scopus citations

Expressing the mind

Mirnics, K. & Blakemore, J. G., Jan 2012, In : Neurobiology of Disease. 45, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Gene expression profiling of the brain: Pondering facts and fiction

Mitchell, A. C. & Mirnics, K., Jan 2012, In : Neurobiology of Disease. 45, 1, p. 3-7 5 p.

Research output: Contribution to journalReview article

11 Scopus citations

Gene transcripts associated with BMI in the motor cortex and caudate nucleus of calorie restricted rhesus monkeys

Mitchell, A. C., Leak, R. K., Zigmond, M. J., Cameron, J. L. & Mirnics, K., Mar 2012, In : Genomics. 99, 3, p. 144-151 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Immune system gene dysregulation in autism and schizophrenia

Michel, M., Schmidt, M. J. & Mirnics, K., Oct 2012, In : Developmental Neurobiology. 72, 10, p. 1277-1287 11 p.

Research output: Contribution to journalArticle

62 Scopus citations

Modeling interneuron dysfunction in Schizophrenia

Schmidt, M. J. & Mirnics, K., Sep 2012, In : Developmental Neuroscience. 34, 2-3, p. 152-158 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Physical activity-associated gene expression signature in nonhuman primate motor cortex

Mitchell, A. C., Leak, R. K., Garbett, K., Zigmond, M. J., Cameron, J. L. & Mirnics, K., Mar 2012, In : Obesity. 20, 3, p. 692-698 7 p.

Research output: Contribution to journalArticle

2 Scopus citations