• 321 Citations
  • 10 h-Index
19992020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2020

IL-33/IL1RL1 axis regulates cell survival through the p38 MAPK pathway in acute myeloid leukemia

Wang, Y., Luo, H., Wei, M., Becker, M., Hyde, R. K. & Gong, Q., Sep 2020, In : Leukemia Research. 96, 106409.

Research output: Contribution to journalArticle

Use of polymeric CXCR4 inhibitors as siRNA delivery vehicles for the treatment of acute myeloid leukemia

Wang, Y., Xie, Y., Williams, J., Hang, Y., Richter, L., Becker, M., Amador, C., Oupický, D. & Hyde, R. K., Feb 1 2020, In : Cancer Gene Therapy. 27, 1-2, p. 45-55 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
2019

HDAC1 is a required cofactor of CBFb-SMMHC and a potential therapeutic target in inversion 16 acute myeloid leukemia

Richter, L. E., Wang, Y., Becker, M. E., Coburn, R. A., Williams, J. T., Amador, C. & Hyde, R. K., Jun 1 2019, In : Molecular Cancer Research. 17, 6, p. 1241-1252 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

IL1RL1 is dynamically expressed on Cbfb-MYH11 + leukemia stem cells and promotes cell survival

Wang, Y., Richter, L., Becker, M., Amador, C. & Hyde, R. K., Dec 1 2019, In : Scientific reports. 9, 1, 1729.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2017

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11

Zhen, T., Kwon, E. M., Zhao, L., Hsu, J., Hyde, R. K., Lu, Y., Alemu, L., Speck, N. A. & Liu, P. P., Nov 30 2017, In : Blood. 130, 22, p. 2431-2442 12 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia

Richter, L., Wang, Y. & Hyde, R. K., 2016, In : Oncotarget. 7, 40, p. 66255-66266 12 p.

Research output: Contribution to journalArticle

3 Scopus citations
2015

Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice

Hyde, R. K., Zhao, L., Alemu, L. & Liu, P. P., Aug 7 2015, In : Leukemia. 29, 8, p. 1771-1778 8 p.

Research output: Contribution to journalArticle

27 Scopus citations
2013

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis

Kamikubo, Y., Hyde, R. K., Zhao, L., Alemu, L., Rivas, C., Garrett, L. J. & Liu, P. P., Jan 24 2013, In : Blood. 121, 4, p. 638-642 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
2012

Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interaction

Cunningham, L., Finckbeiner, S., Hyde, R. K., Southall, N., Marugan, J., Yedavalli, V. R. K., Dehdashti, S. J., Reinhold, W. C., Alemu, L., Zhao, L., Yeh, J. R. J., Sood, R., Pommier, Y., Austin, C. P., Jeang, K. T., Zheng, W. & Liu, P., Sep 4 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 36, p. 14592-14597 6 p.

Research output: Contribution to journalArticle

60 Scopus citations
2011

GATA2 mutations lead to MDS and AML

Hyde, R. K. & Liu, P. P., Oct 2011, In : Nature Genetics. 43, 10, p. 926-927 2 p.

Research output: Contribution to journalArticle

24 Scopus citations

Interfering with cancer

Hyde, K. & Liu, P., Jan 1 2011, In : Scientist. 25, 1, 1 p.

Research output: Contribution to journalArticle

2010

Accelerated Leukemogenesis by Truncated CBFβ-SMMHC Defective in High-Affinity Binding with RUNX1

Kamikubo, Y., Zhao, L., Wunderlich, M., Corpora, T., Hyde, R. K., Paul, T. A., Kundu, M., Garrett, L., Compton, S., Huang, G., Wolff, L., Ito, Y., Bushweller, J., Mulloy, J. C. & Liu, P. P., May 18 2010, In : Cancer Cell. 17, 5, p. 455-468 14 p.

Research output: Contribution to journalArticle

26 Scopus citations

Cbfb/Runx1 repression-independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11

Hyde, R. K., Kamikubo, Y., Anderson, S., Kirby, M., Alemu, L., Zhao, L. & Liu, P. P., Feb 18 2010, In : Blood. 115, 7, p. 1433-1443 11 p.

Research output: Contribution to journalArticle

28 Scopus citations
2006
17 Scopus citations
2005

Examination of the pRb-dependent and pRb-independent functions of E7 in vivo

Balsitis, S., Dick, F., Lee, D., Farrell, L., Hyde, R. K., Griep, A. E., Dyson, N. & Lambert, P. F., Sep 2005, In : Journal of virology. 79, 17, p. 11392-11402 11 p.

Research output: Contribution to journalArticle

46 Scopus citations
2002

Unique roles for E2F1 in the mouse lens in the absence of functional pRB proteins

Hyde, R. K. & Griep, A. E., 2002, In : Investigative Ophthalmology and Visual Science. 43, 5, p. 1509-1516 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2001

The Position of the α and β Subunits in a Single Chain Variant of Human Chorionic Gonadotropin Affects the Heterodimeric Interaction of the Subunits and Receptor-binding Epitopes

Ben-Menahem, D., Jablonka-Shariff, A., Hyde, R. K., Pixley, M. R., Srivastava, S., Berger, P. & Boime, I., Aug 10 2001, In : Journal of Biological Chemistry. 276, 32, p. 29871-29879 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
1999

Synthesis of multi-subunit domain gonadotropin complexes: A model for α/β heterodimer formation

Ben-Menahem, D., Hyde, R., Pixley, M., Berger, P. & Boime, I., Nov 16 1999, In : Biochemistry. 38, 46, p. 15070-15077 8 p.

Research output: Contribution to journalArticle

15 Scopus citations