• 8310 Citations
  • 44 h-Index
1979 …2019

Research output per year

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Research Output

  • 8310 Citations
  • 44 h-Index
  • 136 Article
  • 6 Chapter
  • 2 Editorial
  • 1 Review article
2019

Thermodynamic contributions for the inclusion of bulges and mismatches in dna hairpin loops

Shikiya, R. & Marky, L. A., Jun 5 2019, A Closer Look at Calorimetry. Nova Science Publishers, Inc., p. 31-60 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Thermodynamic investigation of kissing-loop interactions

Carr, C. E. & Marky, L. A., Feb 2019, In : Biochimie. 157, p. 177-183 7 p.

Research output: Contribution to journalArticle

2018

Effect of dC → d(m5C) substitutions on the folding of intramolecular triplexes with mixed TAT and C+GC base triplets

Carr, C. E., Ganugula, R., Shikiya, R., Soto, A. M. & Marky, L. A., Mar 2018, In : Biochimie. 146, p. 156-165 10 p.

Research output: Contribution to journalArticle

Effect of GCAA stabilizing loops on three- and four-way intramolecular junctions

Carr, C. E. & Marky, L. A., 2018, In : Physical Chemistry Chemical Physics. 20, 7, p. 5046-5056 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Energetics, Ion, and Water Binding of the Unfolding of AA/UU Base Pair Stacks and UAU/UAU Base Triplet Stacks in RNA

Carr, C. E., Khutsishvili, I. & Marky, L. A., Jul 19 2018, In : Journal of Physical Chemistry B. 122, 28, p. 7057-7065 9 p.

Research output: Contribution to journalArticle

Increased Flexibility between Stems of Intramolecular Three-Way Junctions by the Insertion of Bulges

Carr, C. E. & Marky, L. A., Jun 19 2018, In : Biophysical journal. 114, 12, p. 2764-2774 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Thermodynamic Stability of DNA Duplexes Comprising the Simplest T → du Substitutions

Carr, C. E., Khutsishvili, I., Gold, B. & Marky, L. A., Oct 2 2018, In : Biochemistry. 57, 39, p. 5666-5671 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Unfolding and Targeting Thermodynamics of a DNA Intramolecular Complex with Joined Triplex-Duplex Domains

Johnson, S. E., Reiling-Steffensmeier, C., Lee, H. T. & Marky, L. A., Jan 25 2018, In : Journal of Physical Chemistry B. 122, 3, p. 1102-1111 10 p.

Research output: Contribution to journalArticle

Unfolding thermodynamics of nucleic acids: Determining heat capacity effects using differential scanning calorimetry (DSC)

Carr, C. E., Reiling-Steffensmeier, C., Khutsishvili, I. & Marky, L. A., Jan 1 2018, Differential Scanning Calorimetry: Basics and Applications. Nova Science Publishers, Inc., p. 1-41 41 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2017

Effect of Loop Length and Sequence on the Stability of DNA Pyrimidine Triplexes with TAT Base Triplets

Lee, H. T., Carr, C. E., Khutsishvili, I. & Marky, L. A., Oct 5 2017, In : Journal of Physical Chemistry B. 121, 39, p. 9175-9184 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Investigation of the Melting Behavior of DNA Three-Way Junctions in the Closed and Open States

Carr, C. E. & Marky, L. A., Aug 8 2017, In : Biophysical journal. 113, 3, p. 529-539 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Melting Behavior of a DNA Four-Way Junction Using Spectroscopic and Calorimetric Techniques

Carr, C. E. & Marky, L. A., Oct 18 2017, In : Journal of the American Chemical Society. 139, 41, p. 14443-14455 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Structural Insight into the Unbound State of the DNA Analogue of the PreQ1 Riboswitch: A Thermodynamic Approach

Reiling-Steffensmeier, C. & Marky, L. A., Nov 28 2017, In : Biochemistry. 56, 47, p. 6231-6239 9 p.

Research output: Contribution to journalArticle

Tuning polypeptide-based micellar carrier for efficient combination therapy of ErbB2-positive breast cancer

Soni, K. S., Lei, F., Desale, S. S., Marky, L. A., Cohen, S. M. & Bronich, T. K., Oct 28 2017, In : Journal of Controlled Release. 264, p. 276-287 12 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Application of differential scanning calorimetry to measure the differential binding of ions, water and protons in the unfolding of DNA molecules

Olsen, C. M., Shikiya, R., Ganugula, R., Reiling-Steffensmeier, C., Khutsishvili, I., Johnson, S. E. & Marky, L. A., May 1 2016, In : Biochimica et Biophysica Acta - General Subjects. 1860, 5, p. 990-998 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

The Complementarity of the Loop to the Stem in DNA Pseudoknots Gives Rise to Local TAT Base-Triplets

Reiling-Steffensmeier, C. & Marky, L. A., 2016, In : Methods in Enzymology. 567, p. 413-432 20 p.

Research output: Contribution to journalArticle

1 Scopus citations
2015

Loop contributions to the folding thermodynamics of DNA straight hairpin loops and pseudoknots

Reiling, C., Khutsishvili, I., Huang, K. & Marky, L. A., Feb 5 2015, In : Journal of Physical Chemistry A. 119, 5, p. 1939-1946 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

The size of the internal loop in DNA hairpins influences their targeting with partially complementary strands

Prislan, I., Lee, H. T., Lee, C. & Marky, L. A., Jan 8 2015, In : Journal of Physical Chemistry B. 119, 1, p. 96-104 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Interaction of DNA intramolecular structures with their complementary strands: A thermodynamic approach for the control of gene expression

Khutsishvili, I., Johnson, S. E., Reiling, C., Prislan, I., Lee, H. T. & Marky, L. A., Jan 1 2014, Chemical Biology of Nucleic Acids: Fundamentals and Clinical Applications. Springer Berlin Heidelberg, p. 367-383 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Looking for waldo: A potential thermodynamic signature to DNA damage

Gold, B., Stone, M. P. & Marky, L. A., Apr 15 2014, In : Accounts of Chemical Research. 47, 4, p. 1446-1454 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core

Simone, P. D., Struble, L. R., Kellezi, A., Brown, C. A., Grabow, C. E., Khutsishvili, I., Marky, L. A., Pavlov, Y. I. & Borgstahl, G. E. O., Jun 2013, In : Journal of Structural Biology. 182, 3, p. 197-208 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions

Khutsishvili, I., Zhang, N., Marky, L. A., Crean, C., Patel, D. J., Geacintov, N. E. & Shafirovich, V., Feb 26 2013, In : Biochemistry. 52, 8, p. 1354-1363 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
2012

Prevention of orthopedic device-associated osteomyelitis using oxacillin-containing biomineral-binding liposomes

Liu, X. M., Zhang, Y., Chen, F., Khutsishvili, I., Fehringer, E. V., Marky, L. A., Bayles, K. W. & Wang, D., Nov 2012, In : Pharmaceutical Research. 29, 11, p. 3169-3179 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Probing the temperature unfolding of a variety of DNA secondary structures using the fluorescence properties of 2-aminopurine

Lee, H. T., Waters, L., Olsen, C. M., Khutsishvili, I. & Marky, L. A., 2012, In : Acta Chimica Slovenica. 59, 3, p. 443-453 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Rabankyrin-5 Interacts with EHD1 and Vps26 to Regulate Endocytic Trafficking and Retromer Function

Zhang, J., Reiling, C., Reinecke, J. B., Prislan, I., Marky, L. A., Sorgen, P. L., Naslavsky, N. & Caplan, S., May 2012, In : Traffic. 13, 5, p. 745-757 13 p.

Research output: Contribution to journalArticle

33 Scopus citations
2011

Altering the electrostatic potential in the major groove: Thermodynamic and structural characterization of 7-deaza-2′-deoxyadenosine:dT base pairing in DNA

Kowal, E. A., Ganguly, M., Pallan, P. S., Marky, L. A., Gold, B., Egli, M. & Stone, M. P., Dec 1 2011, In : Journal of Physical Chemistry B. 115, 47, p. 13925-13934 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

A thermodynamic approach for the targeting of nucleic acid structures using their complementary single strands

Lee, H. T., Carr, C., Siebler, H., Waters, L., Khutsishvili, I., Iseka, F., Domack, B., Olsen, C. M. & Marky, L. A., 2011, In : Methods in Enzymology. 492, p. 1-26 26 p.

Research output: Contribution to journalArticle

10 Scopus citations

Characterization of DNA with an 8-oxoguanine modification

Singh, S. K., Szulik, M. W., Ganguly, M., Khutsishvili, I., Stone, M. P., Marky, L. A. & Gold, B., Aug 2011, In : Nucleic acids research. 39, 15, p. 6789-6801 13 p.

Research output: Contribution to journalArticle

48 Scopus citations

Core cross-linked block ionomer micelles as pH-responsive carriers for cis-diamminedichloroplatinum(II)

Oberoi, H. S., Laquer, F. C., Marky, L. A., Kabanov, A. V. & Bronich, T. K., Jul 15 2011, In : Journal of Controlled Release. 153, 1, p. 64-72 9 p.

Research output: Contribution to journalArticle

74 Scopus citations
15 Scopus citations

Interaction of minor groove ligands with G-quadruplexes: Thermodynamic contributions of the number of quartets, T-U substitutions, and conformation

Prislan, I., Khutsishvili, I. & Marky, L. A., Aug 2011, In : Biochimie. 93, 8, p. 1341-1350 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Melting behavior and ligand binding of DNA intramolecular secondary structures

Maiti, S., Kankia, B., Khutsishvili, I. & Marky, L. A., Nov 2011, In : Biophysical Chemistry. 159, 1, p. 162-171 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
12 Scopus citations

Synthesis and application of functional nucleic acids

Miyoshi, D., Simmel, F. C., Maiti, S. & Marky, L. A., 2011, In : Journal of Nucleic Acids. 2011, 547245.

Research output: Contribution to journalEditorial

1 Scopus citations

The size of internal loops influences the unfolding thermodynamics of DNA hairpins

Prislan, I., Lee, H. T., Lee, C. & Marky, L. A., Oct 25 2011, Frontiers in Nucleic Acids. American Chemical Society, p. 93-110 18 p. (ACS Symposium Series; vol. 1082).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

The stability of a model substrate for topoisomerase 1-mediated DNA religation depends on the presence of mismatched base pairs

Gmeiner, W. H., Salsbury, F., Olsen, C. M. & Marky, L. A., 2011, In : Journal of Nucleic Acids. 2011, 631372.

Research output: Contribution to journalArticle

10 Scopus citations
2010

DNA complexes containing joined triplex and duplex motifs: Melting behavior of intramolecular and bimolecular complexes with similar sequences

Lee, H. T., Khutsishvili, I. & Marky, L. A., Jan 14 2010, In : Journal of Physical Chemistry B. 114, 1, p. 541-548 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
22 Scopus citations
13 Scopus citations
2009

Energetic and hydration contributions of the removal of methyl groups from thymine to form uracil in G-quadruplexes

Olsen, C. M. & Marky, L. A., Jan 8 2009, In : Journal of Physical Chemistry B. 113, 1, p. 9-11 3 p.

Research output: Contribution to journalArticle

27 Scopus citations

Functional Study of the P32T ITPA Variant Associated with Drug Sensitivity in Humans

Stepchenkova, E. I., Tarakhovskaya, E. R., Spitler, K., Frahm, C., Menezes, M. R., Simone, P. D., Kolar, C., Marky, L. A., Borgstahl, G. E. O. & Pavlov, Y. I., Sep 25 2009, In : Journal of Molecular Biology. 392, 3, p. 602-613 12 p.

Research output: Contribution to journalArticle

49 Scopus citations
7 Scopus citations

Unfolding thermodynamics of DNA intramolecular complexes involving joined triple- and double-helical motifs.

Khutsishvili, I., Johnson, S., Lee, H. T. & Marky, L. A., 2009, In : Methods in enzymology. 466, p. 477-502 26 p.

Research output: Contribution to journalArticle

11 Scopus citations

Unfolding thermodynamics of intramolecular G-quadruplexes: Base sequence contributions of the loops

Olsen, C. M., Lee, H. T. & Marky, L. A., Mar 5 2009, In : Journal of Physical Chemistry B. 113, 9, p. 2587-2595 9 p.

Research output: Contribution to journalArticle

57 Scopus citations
2008
11 Scopus citations

Thermodynamic contributions of the reactions of DNA intramolecular structures with their complementary strands

Lee, H. T., Olsen, C. M., Waters, L., Sukup, H. & Marky, L. A., Jul 2008, In : Biochimie. 90, 7, p. 1052-1063 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Unfolding thermodynamics of DNA pyrimidine triplexes with different molecularities

Lee, H. T., Arciniegas, S. & Marky, L. A., Apr 17 2008, In : Journal of Physical Chemistry B. 112, 15, p. 4833-4840 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
2007

A study of 7-deaza-2′-deoxyguanosine-2′-deoxycytidine base pairing in DNA

Ganguly, M., Wang, F., Kaushik, M., Stone, M. P., Marky, L. A. & Gold, B., Sep 2007, In : Nucleic acids research. 35, 18, p. 6181-6195 15 p.

Research output: Contribution to journalArticle

32 Scopus citations

Building Blocks of Nucleic Acid Nanostructures: Unfolding Thermodynamics of Intramolecular DNA Complexes

Marky, L. A., Maiti, S., Olsen, C., Shikiya, R., Johnson, S. E., Kaushik, M. & Khutsishvili, I., Jan 3 2007, Biomedical Applications of Nanotechnology. John Wiley & Sons, Inc., p. 191-226 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

15 Scopus citations

Calorimetric unfolding of the bimolecular and i-motif complexes of the human telomere complementary strand, d(C3TA2)4

Kaushik, M., Suehl, N. & Marky, L. A., Mar 2007, In : Biophysical Chemistry. 126, 1-3, p. 154-164 11 p.

Research output: Contribution to journalArticle

65 Scopus citations