Lynell Warren Klassen, MD

Professor

  • 4659 Citations
  • 36 h-Index
1972 …2021

Research output per year

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Research Output

1972

Experimental medullary aplasia

Klassen, L. W., Birks, J., Allen, E. & Gurney, C. W., Jul 1972, In : The Journal of Laboratory and Clinical Medicine. 80, 1, p. 8-17 10 p.

Research output: Contribution to journalArticle

22 Scopus citations
1975

Hypoxia-induced thrombocytopenia in mice

Birks, J. W., Klassen, L. W. & Gurney, C. W., Aug 1975, In : The Journal of Laboratory and Clinical Medicine. 86, 2, p. 230-238 9 p.

Research output: Contribution to journalArticle

46 Scopus citations
1976

Sex differences in formation of anti-T-cell antibodies

Raveche, E. S., Klassen, L. W. & Steinberg, A. D., Dec 1 1976, In : Nature. 263, 5576, p. 415-416 2 p.

Research output: Contribution to journalArticle

32 Scopus citations
1977

Ribavirin: Efficacy in the treatment of murine autoimmune disease

Klassen, L. W., Budman, D. R., Williams, G. W., Steinberg, A. D. & Gerber, N. L., Jan 1 1977, In : Science. 195, 4280, p. 787-789 3 p.

Research output: Contribution to journalArticle

22 Scopus citations

Role of suppressor T cells in lymphopoietic disorders.

Steinberg, A. D. & Klassen, L. W., Jun 1 1977, In : Clinics in Haematology. 6, 2, p. 439-478 40 p.

Research output: Contribution to journalReview article

14 Scopus citations

Selective loss of suppressor cell function in New Zealand mice induced by NTA

Klassen, L. W., Krakauer, R. S. & Steinberg, A. D., Dec 1 1977, In : Journal of Immunology. 119, 3, p. 830-837 8 p.

Research output: Contribution to journalArticle

84 Scopus citations

Suppressor cell activation by anti-Thy 1.2 in NZB/WC1 mice

Klassen, L. W., Zarate, A., Gelfand, M. C. & Steinberg, A. D., Dec 1 1977, In : Journal of Immunology. 119, 6, p. 2067-2072 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
1978

Effect of the anti‐estrogen, nafoxidine, on nzb/w autoimmune disease

Duvic, M., Steinberg, A. D. & Klassen, L. W., May 1978, In : Arthritis & Rheumatism. 21, 4, p. 414-417 4 p.

Research output: Contribution to journalArticle

33 Scopus citations

Genetic studies in NZB mice: I. Spontaneous autoantibody production

Raveché, E. S., Steinberg, A. D., Klassen, L. W. & Tjio, J. H., May 1 1978, In : Journal of Experimental Medicine. 147, 5, p. 1487-1502 16 p.

Research output: Contribution to journalArticle

Open Access
66 Scopus citations

Influenza immunization in systemic lupus erythematosus. A double-blind trial

Williams, G. W., Steinberg, A. D., Reinertsen, J. L., Klassen, L. W., Decker, J. L. & Dolin, R., Jan 1 1978, In : Unknown Journal. 88, 6, p. 729-734 6 p.

Research output: Contribution to journalArticle

99 Scopus citations

Study of the multiple factors in the pathogenesis of autoimmunity in new zealand mice

Steinberg, A. D., Klassen, L. W., Raveche, E. S., Gerber, N. L., Reinertsen, J. L., Krakauer, R. S., Ranney, D. F., Gershwin, M. E., Williams, G. W., Kovacs, K. & Reeves, J. P., Jun 1978, In : Arthritis & Rheumatism. 21, 1 S, p. S190-S201

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Therapeutic studies in NZB/NZW mice.

Steinberg, A. D., Krakauer, R., Reinertsen, J. L., Klassen, L. W., Ilfeld, D., Reeves, J. P., Williams, G. W. & Antonovych, T., Mar 1978, In : Arthritis & Rheumatism. 21, 2, p. 204-209 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
1979

Immunofluorescence studies of anti‐t cell antibodies and t cells in systemic lupus erythematosus

Steinberg, A. D., Klassen, L. W., Budman, D. R. & Williams, G. W., Feb 1979, In : Arthritis & Rheumatism. 22, 2, p. 114-122 9 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

Retention of DR-specific memory in primed lymphocytes grown in PHA-conditioned media

Brown, S., Maca, R., Klassen, L., Goeken, N., Severson, C. & Thompson, J., Dec 1 1979, In : Transplantation Proceedings. 11, 4, p. 1982-1985 4 p.

Research output: Contribution to journalArticle

Ribavirin treatment in murine autoimmune disease

Klassen, L. W., Williams, G. W., Reinertsen, J. L., Gerber, N. L. & Steinberg, A. D., Feb 1979, In : Arthritis & Rheumatism. 22, 2, p. 145-154 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Studies on the pathogenesis of levamisole (LEV)-induced agranulocytosis

Thompson, J. S., Herbick, J. M. & Klassen, L., Jan 1 1979, In : Clinical Research. 27, 4, p. 695A

Research output: Contribution to journalArticle

1980

Studies on levamisole-induced agranulocytosis

Thompson, J. S., Herbick, J. M., Klassen, L. W., Severson, C. D., Overlin, V. L., Blaschke, J. W., Silverman, M. A. & Vogel, C. L., Dec 1 1980, In : Blood. 56, 3, p. 388-396 9 p.

Research output: Contribution to journalArticle

54 Scopus citations
1981

Allogeneic bone marrow transplantation (BMT) for the treatment of acute leukemia

Armitage, J., Klassen, L. & Kugler, J., Jan 1 1981, In : Clinical Research. 29, 5, p. 842 A

Research output: Contribution to journalArticle

1 Scopus citations

Human suppressor cells: evidence of functionally distinct subsets

Goeken, N. E., Thompson, J. S., Klassen, L. & Brown, S., Feb 1981, In : Human Immunology. 2, 1, p. 65-76 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Toxic shock syndrome: A retrospective study of 25 cases from Iowa

Helms, C. M., Lengeling, R. W., Pinsky, R. L., Myers, M. G., Koontz, F. P., Klassen, L. W. & Wintermeyer, L. A., Jan 1 1981, In : Unknown Journal. 282, 2, p. 50-60 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
1982

Cytomegalovirus cecal erosion causing massive hemorrhage in a bone marrow transplant recipient

West, J. C., Armitage, J. O., Mitros, F. A., Klassen, L. W., Corry, R. J. & Ray, T., Mar 1 1982, In : World Journal of Surgery. 6, 2, p. 251-254 4 p.

Research output: Contribution to journalArticle

16 Scopus citations
1983

Nosocomial Legionnaires' disease. Occurrence in recipients of bone marrow transplants

Kugler, J. W., Armitage, J. O., Helms, C. M., Klassen, L. W., Goeken, N. E., Ahmann, G. B., Gingrich, R. D., Johnson, W. & Gilchrist, M. J. R., Feb 1983, In : The American journal of medicine. 74, 2, p. 281-288 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

Nosocomial legionnaires' disease. Occurrence in recipients of bone nmarrow transplants

Kugler, J. W., Armitage, J. O., Helms, C. M., Klassen, L. W., Goeken, N. E., Ahmann, G. B., Gingrich, R. D., Johnson, W. & Gilchrist, M. J. R., Jan 1 1983, In : Unknown Journal. 74, 2, p. 281-288 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
1984

A comparison of bone marrow transplantation with maintenance chemotherapy for patients with acute nonlymphoblastic leukemia in first complete remission

Armitage, J. O., Klassen, L. W., Burns, C. P., Kugler, J. W., Ray, T. L., Gingrich, R. D., Ahmann, G. B. & Tewfik, H. H., Jan 1 1984, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 7, 3, p. 273-278 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Acute graft-versus-host disease resulting from normal donor blood transfusions1

Burns, L. J., Westberg, M. W., Patrick Burns, C., Klassen, L. W., Goeken, N. E., Ray, T. L. & Macfarlane, D. E., Jan 1 1984, In : Acta Haematologica. 71, 4, p. 270-276 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Hyporesponse to interleukin-2 associated with chronic lymphocyte activation in primary biliary cirrhosis (PBC)

Scribner, C. L., Klassen, L. W. & Schafer, D. F., Jan 1 1984, In : Federation Proceedings. 43, 7, p. no. 2952

Research output: Contribution to journalArticle

Inhibition of human natural killer (NK) lymphocyte activity by apotransferrin (TF)

Bierman, P. J., Petrie, H. T., Klassen, L. W. & Kay, H. D., Jan 1 1984, In : Federation Proceedings. 43, 6, p. no. 2272

Research output: Contribution to journalArticle

Marrow transplantation for stable-phase chronic granulocytic leukemia

Armitage, J. O., Klassen, L. W., Patil, S. R., Kugler, J. W., Gingrich, R. D., Ahmann, G. B., Fyfe, M. A. & Tewfik, H. H., Dec 6 1984, In : Experimental Hematology. 12, 9, p. 717-719 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
1985

Human natural killer (NK) cell function is reversibly inhibited by selenium

Kay, H. D., Petrie, H. T. & Klassen, L. W., Jan 1 1985, In : Federation Proceedings. 44, 3, p. No. 1041

Research output: Contribution to journalArticle

Inhibition of human cytotoxic T lymphocyte activity in vitro by autologous peripheral blood granulocytes

Petrie, H. T., Klassen, L. W. & Kay, H. D., Jan 1 1985, In : Journal of Immunology. 134, 1, p. 230-234 5 p.

Research output: Contribution to journalArticle

141 Scopus citations

Reversible inhibition of human lymphoproliferative response by selenium

Petrie, H. T., Tempero, M. A., Klassen, L. W. & Kay, H. D., Jan 1 1985, In : Federation Proceedings. 44, 4, p. No. 5258

Research output: Contribution to journalArticle

The use of partially matched, unrelated donors in clinical bone marrow transplantation

Gingrich, R. D., Howe, C. W. S., Goeken, N. E., Ginder, G. D., Kugler, J. W., Tewfik, H. H., Klassen, L. W., Armitage, J. O. & Fyfe, M. A., May 1985, In : Transplantation. 39, 5, p. 526-532 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
1986

Effect of high-dose cyclophosphamide and total-body irradiation on left ventricular function in adult patients with leukemia undergoing allogeneic bone marrow transplantation

Baello, E. B., Ensberg, M. E., Ferguson, D. W., Kugler, J. W., Gingrich, R. D., Armitage, J. O., Klassen, L. W., Kirchner, P. T., Kerber, R. E. & Marcus, M. L., Dec 30 1986, In : Cancer treatment reports. 70, 10, p. 1187-1193 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Interleukin-2-induced chemotaxis of human T-lymphocytes

Robbins, R. A., Klassen, L., Rasmussen, J., Clayton, M. E. & Russ, W. D., Dec 19 1986, In : Journal of Laboratory and Clinical Medicine. 108, 4, p. 340-345 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Interleukin-2-induced chemotaxis of human T-lymphocytes

Robbins, R. A., Klassen, L., Rasmussen, J., Clayton, M. E. M. & Russ, W. D., Oct 1986, In : The Journal of Laboratory and Clinical Medicine. 108, 4, p. 332-339 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

In vitro effects of selenium and T-cell growth factor (TCGF) on natural killer (NK) cell function of lymphocytes from human peripheral blood

Kay, H. D., Petrie, H. T. & Klassen, L. W., Jan 1 1986, In : IRCS Medical Science. 14, 7, p. 691-692 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

In vitro regulation of human lymphocyte proliferation by selenium

Petrie, H. T., Klassen, L. W., Tempero, M. A. & Kay, H. D., Dec 1 1986, In : Biological Trace Element Research. 11, 1, p. 129-146 18 p.

Research output: Contribution to journalArticle

12 Scopus citations

Peripheral blood granulocytes as effectors of regulation for the human natural killer cell system. A review

Kay, H. D. & Klassen, L. W., Jan 1 1986, In : Natural Immunity and Cell Growth Regulation. 5, 1, p. 1-18 18 p.

Research output: Contribution to journalReview article

5 Scopus citations

Rapid recovery of non-hemolyzed serum and untraumatized cells by using a new method of blood defibrination in vitro

David Kay, H., Petrie, H. T., Burge, J. J. & Klassen, L. W., Sep 27 1986, In : Journal of Immunological Methods. 92, 2, p. 251-260 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Trial of high-dose cytarabine, cyclophosphamide, total-body irradiation, and autologous marrow transplantation for refractory lymphoma

Armitage, J. O., Gingrich, R. D., Klassen, L. W., Bierman, P. J., Kumar, P. P., Weisenburger, D. D. & Smith, D. M., Sep 24 1986, In : Cancer treatment reports. 70, 7, p. 871-875 5 p.

Research output: Contribution to journalArticle

30 Scopus citations
1987

Bone marrow patterns in aplastic anemia: Observations with 1.5-T MR imaging

Kaplan, P. A., Asleson, R. J., Klassen, L. W. & Duggan, M. J., Jan 1 1987, In : Radiology. 164, 2, p. 441-444 4 p.

Research output: Contribution to journalArticle

44 Scopus citations

Graft versus host disease following transfusion of normal blood products to patients with malignancies

Kessinger, A., Armitage, J. O., Klassen, L. W., Landmark, J. D., Hayes, J. M., Larsen, A. E. & Purtilo, D. T., Nov 1987, In : Journal of Surgical Oncology. 36, 3, p. 206-209 4 p.

Research output: Contribution to journalArticle

23 Scopus citations
1988

Improved survival in murine lupus as the result of selenium supplementation

O'Dell, J. R., McGivern, J. P., Kay, H. D. & Klassen, L. W., Jan 1 1988, In : Clinical and Experimental Immunology. 73, 2, p. 322-327 6 p.

Research output: Contribution to journalArticle

16 Scopus citations
1989

Allogeneic bone marrow transplantation in patients with lymphoma relapsing after autologous marrow transplantation

Schouten, H. C., Armitage, J. O., Klassen, L. W., Vaughan, W. P., Bierman, P. J., Weisenburger, D. & Kessinger, A., Jan 1 1989, In : Bone marrow transplantation. 4, 1, p. 119-121 3 p.

Research output: Contribution to journalArticle

15 Scopus citations

Bronchial epithelial cells release chemotactic activity for lymphocytes

Robbins, R. A., Shoji, S., Linder, J., Gossman, G. L., Allington, L. A., Klassen, L. W. & Rennard, S. I., Jan 1 1989, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 257, 2, p. 1/1

Research output: Contribution to journalArticle

12 Scopus citations

Selenium and the immune response: 2. Enhancement of murine cytotoxic T-lymphocyte and natural killer cell cytotoxicity in vivo

Petrie, H. T., Klassen, L. W., Klassen, P. S., O'Dell, J. R. & Kay, H. D., Jan 1 1989, In : Journal of Leukocyte Biology. 45, 3, p. 215-220 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Selenium and the immune response: 1. Modulation of alloreactive human lymphocyte functions in vitro

Petrie, H. T., Klassen, L. W. & Kay, H. D., Jan 1 1989, In : Journal of Leukocyte Biology. 45, 3, p. 207-214 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
1990

Immune response to acetaldehyde adducts.

Klassen, L. W., Xu, D. S. & Tuma, D. J., Jan 1 1990, In : Progress in clinical and biological research. 325, p. 333-340 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Phase II trial of interferon gamma and monoclonal antibody 17-1A in pancreatic cancer: Biologic and clinical effects

Tempero, M. A., Sivinski, C., Steplewski, Z., Harvey, E., Klassen, L. & Kay, H. D., Dec 1990, In : Journal of Clinical Oncology. 8, 12, p. 2019-2026 8 p.

Research output: Contribution to journalArticle

33 Scopus citations
1991
34 Scopus citations