Lynell Warren Klassen, MD

Professor

  • 4659 Citations
  • 36 h-Index
1972 …2021

Research output per year

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Research Output

Article
190 Scopus citations

A comparison of bone marrow transplantation with maintenance chemotherapy for patients with acute nonlymphoblastic leukemia in first complete remission

Armitage, J. O., Klassen, L. W., Burns, C. P., Kugler, J. W., Ray, T. L., Gingrich, R. D., Ahmann, G. B. & Tewfik, H. H., Jan 1 1984, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 7, 3, p. 273-278 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Acute graft-versus-host disease resulting from normal donor blood transfusions1

Burns, L. J., Westberg, M. W., Patrick Burns, C., Klassen, L. W., Goeken, N. E., Ray, T. L. & Macfarlane, D. E., Jan 1 1984, In : Acta Haematologica. 71, 4, p. 270-276 7 p.

Research output: Contribution to journalArticle

31 Scopus citations
46 Scopus citations
8 Scopus citations

Albumin-based microbubbles bind up-regulated scavenger receptors following vascular injury

Anderson, D. R., Duryee, M. J., Anchan, R. K., Garvin, R. P., Johnston, M. D., Porter, T. R., Thiele, G. M. & Klassen, L. W., Dec 24 2010, In : Journal of Biological Chemistry. 285, 52, p. 40645-40653 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease

Schaffert, C. S., Duryee, M. J., Hunter, C. D., Hamilton, B. C., DeVeney, A. L., Hueter, M. M., Klassen, L. W. & Thiele, G. M., Mar 14 2009, In : World Journal of Gastroenterology. 15, 10, p. 1209-1218 10 p.

Research output: Contribution to journalArticle

46 Scopus citations

Aldehydes in cigarette smoke react with the lipid peroxidation product malonaldehyde to form fluorescent protein adducts on lysines

Freeman, T. L., Haver, A., Duryee, M. J., Tuma, D. J., Klassen, L. W., Hamel, F. G., White, R. L., Rennard, S. I. & Thiele, G. M., May 1 2005, In : Chemical Research in Toxicology. 18, 5, p. 817-824 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Allogeneic bone marrow transplantation (BMT) for the treatment of acute leukemia

Armitage, J., Klassen, L. & Kugler, J., Jan 1 1981, In : Clinical Research. 29, 5, p. 842 A

Research output: Contribution to journalArticle

1 Scopus citations

Allogeneic bone marrow transplantation in patients with lymphoma relapsing after autologous marrow transplantation

Schouten, H. C., Armitage, J. O., Klassen, L. W., Vaughan, W. P., Bierman, P. J., Weisenburger, D. & Kessinger, A., Jan 1 1989, In : Bone marrow transplantation. 4, 1, p. 119-121 3 p.

Research output: Contribution to journalArticle

15 Scopus citations

A method for the making and utility of gadolinium-labeled albumin microbubbles

Anderson, D. R., Duryee, M. J., Garvin, R. P., Boska, M. D., Thiele, G. M. & Klassen, L. W., Jan 1 2012, In : Magnetic Resonance Imaging. 30, 1, p. 96-103 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

An in vitro method of alcoholic liver injury using precision-cut liver slices from rats

Klassen, L. W., Thiele, G. M., Duryee, M. J., Schaffert, C. S., DeVeney, A. L., Hunter, C. D., Olinga, P. & Tuma, D. J., Aug 1 2008, In : Biochemical Pharmacology. 76, 3, p. 426-436 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Association of malondialdehyde-acetaldehyde (MAA) adducted proteins with atherosclerotic-induced vascular inflammatory injury

Hill, G. E., Miller, J. A., Baxter, B. T., Klassen, L. W., Duryee, M. J., Tuma, D. J. & Thiele, G. M., Oct 5 1998, In : Atherosclerosis. 141, 1, p. 107-116 10 p.

Research output: Contribution to journalArticle

71 Scopus citations

Autoantibodies from Single Circulating Plasmablasts React with Citrullinated Antigens and Porphyromonas gingivalis in Rheumatoid Arthritis

Li, S., Yu, Y., Yue, Y., Liao, H., Xie, W., Thai, J., Mikuls, T. R., Thiele, G. M., Duryee, M. J., Sayles, H., Payne, J. B., Klassen, L. W., O'Dell, J. R., Zhang, Z. & Su, K., Mar 1 2016, In : Arthritis and Rheumatology. 68, 3, p. 614-626 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

Autoimmune hepatitis induced by syngeneic liver cytosolic proteins biotransformed by alcohol metabolites

Thiele, G. M., Duryee, M. J., Willis, M. S., Tuma, D. J., Radio, S. J., Hunter, C. D., Schaffert, C. S. & Klassen, L. W., Dec 1 2010, In : Alcoholism: Clinical and Experimental Research. 34, 12, p. 2126-2136 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Bone marrow patterns in aplastic anemia: Observations with 1.5-T MR imaging

Kaplan, P. A., Asleson, R. J., Klassen, L. W. & Duggan, M. J., Jan 1 1987, In : Radiology. 164, 2, p. 441-444 4 p.

Research output: Contribution to journalArticle

44 Scopus citations

Bronchial epithelial cells release chemotactic activity for lymphocytes

Robbins, R. A., Shoji, S., Linder, J., Gossman, G. L., Allington, L. A., Klassen, L. W. & Rennard, S. I., Jan 1 1989, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 257, 2, p. 1/1

Research output: Contribution to journalArticle

12 Scopus citations

Celastrol inhibits inflammatory stimuli-induced neutrophil extracellular trap formation

Yu, Y., Koehn, C. D., Yue, Y., Li, S., Thiele, G. M., Hearth-Holmes, M. P., Mikuls, T. R., O’Dell, J. R., Klassen, L. W., Zhang, Z. & Su, K., Jan 1 2015, In : Current Molecular Medicine. 15, 4, p. 401-410 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Chronic ethanol consumption impairs receptor-mediated endocytosis of MAA-modified albumin by liver endothelial cells

Duryee, M. J., Klassen, L. W., Freeman, T. L., Willis, M. S., Tuma, D. J. & Thiele, G. M., Sep 15 2003, In : Biochemical Pharmacology. 66, 6, p. 1045-1054 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Chronic hypervitaminosis A: A case of surreptitious use

Ruskin, J. D., Wendt, S., Klassen, L., Tu, H. K. & Markin, R. S., Jan 1 1992, In : Laboratory medicine. 23, 3, p. 187-189 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
16 Scopus citations

Clinical and immunologic studies in reticular erythematous mucinosis and Jessner's lymphocytic infiltrate of skin

Braddock, S. W., Kay, H. D., Maennle, D., McDonald, T. L., Pirruccello, S. J., Masih, A., Klassen, L. W. & Sawka, A. R., Jan 1 1993, In : Journal of the American Academy of Dermatology. 28, 5, p. 691-695 5 p.

Research output: Contribution to journalArticle

27 Scopus citations
3 Scopus citations
2 Scopus citations
6 Scopus citations

Cytomegalovirus cecal erosion causing massive hemorrhage in a bone marrow transplant recipient

West, J. C., Armitage, J. O., Mitros, F. A., Klassen, L. W., Corry, R. J. & Ray, T., Mar 1 1982, In : World Journal of Surgery. 6, 2, p. 251-254 4 p.

Research output: Contribution to journalArticle

16 Scopus citations

Detection of circulating antibodies against malondialdehyde-acetaldehyde adducts in patients with alcohol-induced liver disease

Rolla, R., Vay, D., Mottaran, E., Parodi, M., Traverso, N., Aricó, S., Sartori, M., Bellomo, G., Klassen, L. W., Thiele, G. M., Tuma, D. J. & Albano, E., Jan 1 2000, In : Hepatology. 31, 4, p. 878-884 7 p.

Research output: Contribution to journalArticle

Open Access
127 Scopus citations

Detection of circulating antibodies to malondialdehyde-acetaldehyde adducts in ethanol-fed rats

Xu, D., Thiele, G. M., Beckenhauer, J. L., Klassen, L. W., Sorrell, M. F. & Tuma, D. J., Jan 1 1998, In : Gastroenterology. 115, 3, p. 686-692 7 p.

Research output: Contribution to journalArticle

70 Scopus citations

Detection of Reduced Acetaldehyde Protein Adducts Using a Unique Monoclonal Antibody

Klassen, L. W., Tuma, D. J., Sorrell, M. F., McDonald, T. L., DeVasure, J. M. & Thiele, G. M., Feb 1994, In : Alcoholism: Clinical and Experimental Research. 18, 1, p. 164-171 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology

Khadge, S., Sharp, J. G., Thiele, G. M., McGuire, T. R., Klassen, L. W., Duryee, M. J., Britton, H. C., Dafferner, A. J., Beck, J., Black, P. N., DiRusso, C. C. & Talmadge, J. E., Feb 2018, In : Journal of Nutritional Biochemistry. 52, p. 92-102 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
14 Scopus citations

Effect of high-dose cyclophosphamide and total-body irradiation on left ventricular function in adult patients with leukemia undergoing allogeneic bone marrow transplantation

Baello, E. B., Ensberg, M. E., Ferguson, D. W., Kugler, J. W., Gingrich, R. D., Armitage, J. O., Klassen, L. W., Kirchner, P. T., Kerber, R. E. & Marcus, M. L., Dec 30 1986, In : Cancer treatment reports. 70, 10, p. 1187-1193 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Effect of the anti‐estrogen, nafoxidine, on nzb/w autoimmune disease

Duvic, M., Steinberg, A. D. & Klassen, L. W., May 1978, In : Arthritis & Rheumatism. 21, 4, p. 414-417 4 p.

Research output: Contribution to journalArticle

33 Scopus citations

Efficacy of triple DMARD therapy in patients with RA with suboptimal response to methotrexate

O'Dell, J. R., Haire, C., Erikson, N., Drymalski, W., Palmer, W., Maloley, P., Klassen, L. W., Wees, S. & Moore, G. F., Mar 1 1996, In : Journal of Rheumatology. 23, SUPPL. 44, p. 72-74 3 p.

Research output: Contribution to journalArticle

46 Scopus citations

Elucidation of reaction scheme describing malondialdehyde - Acetaldehyde - Protein adduct formation

Tuma, D. J., Kearley, M. L., Thiele, G. M., Worrall, S., Haver, A., Klassen, L. W. & Sorrell, M. F., Jul 30 2001, In : Chemical Research in Toxicology. 14, 7, p. 822-832 11 p.

Research output: Contribution to journalArticle

49 Scopus citations

Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint

Mikuls, T. R., Duryee, M. J., Rahman, R., Anderson, D. R., Sayles, H. R., Hollins, A., Michaud, K. D., Wolfe, F., Thiele, G. E., Sokolove, J., Robinson, W. H., Lingampalli, N., Nicholas, A. P., Talmon, G. A., Su, K., Zimmerman, M. C., Klassen, L. W. & Thiele, G. M., Oct 1 2017, In : Rheumatology (Oxford, England). 56, 10, p. 1794-1803 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Epitope characterization of malondialdehyde-acetaldehyde adducts using an enzyme-Linked immunosorbent assay

Xu, D., Thiele, G. M., Kearley, M. L., Haugen, M. D., Klassen, L. W., Sorrell, M. F. & Turna, D. J., Sep 1 1997, In : Chemical Research in Toxicology. 10, 9, p. 978-986 9 p.

Research output: Contribution to journalArticle

60 Scopus citations
34 Scopus citations

Experimental medullary aplasia

Klassen, L. W., Birks, J., Allen, E. & Gurney, C. W., Jul 1972, In : The Journal of Laboratory and Clinical Medicine. 80, 1, p. 8-17 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Exposure of precision-cut rat liver slices to ethanol accelerates fibrogenesis

Schaffert, C. S., Duryee, M. J., Bennett, R. G., DeVeney, A. L., Tuma, D. J., Olinga, P., Easterling, K. C., Thiele, G. M. & Klassen, L. W., Sep 1 2010, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 299, 3, p. G661-G668

Research output: Contribution to journalArticle

19 Scopus citations

Genetic studies in NZB mice: I. Spontaneous autoantibody production

Raveché, E. S., Steinberg, A. D., Klassen, L. W. & Tjio, J. H., May 1 1978, In : Journal of Experimental Medicine. 147, 5, p. 1487-1502 16 p.

Research output: Contribution to journalArticle

Open Access
66 Scopus citations

Graft versus host disease following transfusion of normal blood products to patients with malignancies

Kessinger, A., Armitage, J. O., Klassen, L. W., Landmark, J. D., Hayes, J. M., Larsen, A. E. & Purtilo, D. T., Nov 1987, In : Journal of Surgical Oncology. 36, 3, p. 206-209 4 p.

Research output: Contribution to journalArticle

23 Scopus citations

Halothane potentiates the alcohol-adduct induced TNF-alpha release in heart endothelial cells

Thiele, G. M., Hill, G. E., Pavlik, J. A., Freeman, T. L., Tuma, D. J., Duryee, M. J. & Klassen, L. W., Apr 12 2005, In : BMC Anesthesiology. 5, 3.

Research output: Contribution to journalArticle

1 Scopus citations

High-pressure distention of the saphenous vein during preparation results in increased markers of inflammation: A potential mechanism for graft failure

Khaleel, M. S., Dorheim, T. A., Duryee, M. J., Durbin, H. E., Bussey, W. D., Garvin, R. P., Klassen, L. W., Thiele, G. M. & Anderson, D. R., Feb 1 2012, In : Annals of Thoracic Surgery. 93, 2, p. 552-558 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

HLA-DRB1 typing in rheumatoid arthritis: Predicting response to specific treatments

O'Dell, J. R., Nepom, B. S., Haire, C., Gersuk, V. H., Gaur, L., Moore, G. F., Drymalski, W., Palmer, W., Eckhoff, P. J., Klassen, L. W., Wees, S., Thiele, G. M. & Nepom, G. T., Jan 1 1998, In : Annals of the rheumatic diseases. 57, 4, p. 209-213 5 p.

Research output: Contribution to journalArticle

Open Access
96 Scopus citations

Human natural killer (NK) cell function is reversibly inhibited by selenium

Kay, H. D., Petrie, H. T. & Klassen, L. W., Jan 1 1985, In : Federation Proceedings. 44, 3, p. No. 1041

Research output: Contribution to journalArticle

Human suppressor cells: evidence of functionally distinct subsets

Goeken, N. E., Thompson, J. S., Klassen, L. & Brown, S., Feb 1981, In : Human Immunology. 2, 1, p. 65-76 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Hyporesponse to interleukin-2 associated with chronic lymphocyte activation in primary biliary cirrhosis (PBC)

Scribner, C. L., Klassen, L. W. & Schafer, D. F., Jan 1 1984, In : Federation Proceedings. 43, 7, p. no. 2952

Research output: Contribution to journalArticle

Hypoxia-induced thrombocytopenia in mice

Birks, J. W., Klassen, L. W. & Gurney, C. W., Aug 1975, In : The Journal of Laboratory and Clinical Medicine. 86, 2, p. 230-238 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

IL-6 and its receptors in coronary artery disease and acute myocardial infarction

Anderson, D. R., Poterucha, J. T., Mikuls, T. R., Duryee, M. J., Garvin, R. P., Klassen, L. W., Shurmur, S. W. & Thiele, G. M., Jun 1 2013, In : Cytokine. 62, 3, p. 395-400 6 p.

Research output: Contribution to journalArticle

45 Scopus citations