Lynette M Smith, PhD

  • 11550 Citations
  • 51 h-Index
20012020

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Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex

Gelineau-Van Waes, J., Maddox, J. R., Smith, L. M., Van Waes, M., Wilberding, J., Eudy, J. D., Bauer, L. K. & Finnell, R. H., Apr 9 2008, In : BMC genomics. 9, 156.

Research output: Contribution to journalArticle

20 Scopus citations

Minimal disease assessment in the treatment of children and adolescents with intermediate-risk (Stage III/IV) B-cell non-Hodgkin lymphoma: A children's oncology group report

Shiramizu, B., Goldman, S., Kusao, I., Agsalda, M., Lynch, J., Smith, L., Harrison, L., Morris, E., Gross, T. G., Sanger, W., Perkins, S. & Cairo, M. S., Jun 2011, In : British Journal of Haematology. 153, 6, p. 758-763 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Molecular distinctions between pediatric and adult mature B-cell non-Hodgkin lymphomas identified through genomic profiling

Deffenbacher, K. E., Iqbal, J., Sanger, W., Shen, Y., Lachel, C., Liu, Z., Liu, Y., Lim, M. S., Perkins, S. L., Fu, K., Smith, L., Lynch, J., Staudt, L. M., Rimsza, L. M., Jaffe, E., Rosenwald, A., Ott, G. K., Delabie, J., Campo, E., Gascoyne, R. D. & 5 others, Cairo, M. S., Weisenburger, D. D., Greiner, T. C., Gross, T. G. & Chan, W. C., Apr 19 2012, In : Blood. 119, 16, p. 3757-3766 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma

Iqbal, J., Weisenburger, D. D., Greiner, T. C., Vose, J. M., McKeithan, T., Kucuk, C., Geng, H., Deffenbacher, K., Smith, L., Dybkaer, K., Nakamura, S., Seto, M., Delabie, J., Berger, F., Loong, F., Au, W. Y., Ko, Y. H., Sng, I., Armitage, J. O. & Chan, W. C., Feb 4 2010, In : Blood. 115, 5, p. 1026-1036 11 p.

Research output: Contribution to journalArticle

245 Scopus citations

Morbidity and Mortality Rates Following Cytoreductive Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy Compared With Other High-Risk Surgical Oncology Procedures

Foster, J. M., Sleightholm, R., Patel, A., Shostrom, V., Hall, B., Neilsen, B., Bartlett, D. & Smith, L., Jan 4 2019, In : JAMA Network Open. 2, 1, p. e186847

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

MUC16 contributes to the metastasis of pancreatic ductal adenocarcinoma through focal adhesion mediated signaling mechanism

Muniyan, S., Haridas, D., Chugh, S., Rachagani, S., Lakshmanan, I., Gupta, S., Seshacharyulu, P., Smith, L. M., Ponnusamy, M. P. & Batra, S. K., Mar 2016, In : Genes and Cancer. 7, 3-4, p. 110-124 15 p.

Research output: Contribution to journalArticle

27 Scopus citations

MUC4-mediated regulation of acute phase protein lipocalin 2 through HER2/AKT/NF-κB signaling in pancreatic cancer

Kaur, S., Sharma, N., Krishn, S. R., Lakshmanan, I., Rachagani, S., Baine, M. J., Smith, L. M., Lele, S. M., Sasson, A. R., Guha, S., Mallya, K., Anderson, J. M., Hollingsworth, M. A. & Batra, S. K., 2014, In : Clinical Cancer Research. 20, 3, p. 688-700 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

MUC4 Overexpression Augments Cell Migration and Metastasis through EGFR Family Proteins in Triple Negative Breast Cancer Cells

Mukhopadhyay, P., Lakshmanan, I., Ponnusamy, M. P., Chakraborty, S., Jain, M., Pai, P., Smith, L. M., Lele, S. M. & Batra, S. K., Feb 11 2013, In : PloS one. 8, 2, e54455.

Research output: Contribution to journalArticle

42 Scopus citations

Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer

Krishn, S. R., Kaur, S., Smith, L. M., Johansson, S. L., Jain, M., Patel, A., Gautam, S. K., Hollingsworth, M. A., Mandel, U., Clausen, H., Lo, W. C., Fan, W. T. L., Manne, U. & Batra, S. K., May 1 2016, In : Cancer Letters. 374, 2, p. 304-314 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: Clinical implication for improved colon surveillance

Krishn, S. R., Kaur, S., Sheinin, Y. M., Smith, L. M., Gautam, S. K., Patel, A., Jain, M., Juvvigunta, V., Pai, P., Lazenby, A. J., Roy, H. K. & Batra, S. K., 2017, In : Oncotarget. 8, 4, p. 7025-7038 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mutation and genomic deletion status of ataxia telangiectasia mutated (ATM) and p53 confer specific gene expression profiles in mantle cell lymphoma

Greiner, T. C., Dasgupta, C., Ho, V. V., Weisenburger, D. D., Smith, L. M., Lynch, J. C., Vose, J. M., Fu, K., Armitage, J. O., Braziel, R. M., Campo, E., Delabie, J., Gascoyne, R. D., Jaffe, E. S., Muller-Hermelink, H. K., Ott, G., Rosenwald, A., Staudt, L. M., Im, M. Y., Karaman, M. W. & 3 others, Pike, B. L., Chan, W. C. & Hacia, J. G., Feb 14 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 7, p. 2352-2357 6 p.

Research output: Contribution to journalArticle

100 Scopus citations

Mutations in the DNA-binding codons of TP53, which are associated with decreased expression of TRAIL receptor-2, predict for poor survival in diffuse large B-cell lymphoma

Young, K. H., Weisenburger, D. D., Dave, B. J., Smith, L., Sanger, W., Iqbal, J., Campo, E., Delabie, J., Gascoyne, R. D., Ott, G., Rimsza, L., Müller-Hermelink, H. K., Jaffe, E. S., Rosenwald, A., Staudt, L. M., Chan, W. C. & Greiner, T. C., Dec 15 2007, In : Blood. 110, 13, p. 4396-4405 10 p.

Research output: Contribution to journalArticle

73 Scopus citations

MYC and BCL2 protein expression predicts survival in patients with diffuse large B-cell lymphoma treated with rituximab

Perry, A. M., Alvarado-Bernal, Y., Laurini, J. A., Smith, L. M., Slack, G. W., Tan, K. L., Sehn, L. H., Fu, K., Aoun, P., Greiner, T. C., Chan, W. C., Bierman, P. J., Bociek, R. G., Armitage, J. O., Vose, J. M., Gascoyne, R. D. & Weisenburger, D. D., May 2014, In : British Journal of Haematology. 165, 3, p. 382-391 10 p.

Research output: Contribution to journalArticle

122 Scopus citations

n-3 Docosapentaenoic Acid Intake and Relationship with Plasma Long-Chain n-3 Fatty Acid Concentrations in the United States: NHANES 2003–2014

Richter, C. K., Bisselou, K. S., Nordgren, T. M., Smith, L., Appiah, A. K., Hein, N., Anderson-Berry, A., Kris-Etherton, P., Hanson, C. & Skulas-Ray, A. C., Apr 2019, In : Lipids. 54, 4, p. 221-230 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Nanoformulation of CCL21 greatly increases its effectiveness as an immunotherapy for neuroblastoma

Poelaert, B. J., Romanova, S., Knoche, S. M., Olson, M. T., Sliker, B. H., Smits, K., Dickey, B. L., Moffitt-Holida, A. E. J., Goetz, B. T., Khan, N., Smith, L., Band, H., Mohs, A. M., Coulter, D. W., Bronich, T. K. & Solheim, J. C., Nov 10 2020, In : Journal of Controlled Release. 327, p. 266-283 18 p.

Research output: Contribution to journalArticle

National trends in discharge disposition after hepatic resection for malignancy

Shah, B. C., Ullrich, F., Smith, L., Leiphrakpam, P., Ly, Q., Sasson, A. & Are, C., Feb 2011, In : HPB. 13, 2, p. 96-102 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
23 Scopus citations

Natural killer cell lymphoma shares strikingly similar molecular features with a group of non-hepatosplenic γδ T-cell lymphoma and is highly sensitive to a novel aurora kinase A inhibitor in vitro

Iqbal, J., Weisenburger, D. D., Chowdhury, A., Tsai, M. Y., Srivastava, G., Greiner, T. C., Kucuk, C., Deffenbacher, K., Vose, J., Smith, L., Au, W. Y., Nakamura, S., Seto, M., Delabie, J., Berger, F., Loong, F., Ko, Y. H., Sng, I., Liu, X., Loughran, T. P. & 2 others, Armitage, J. & Chan, W. C., Feb 2011, In : Leukemia. 25, 2, p. 348-358 11 p.

Research output: Contribution to journalArticle

97 Scopus citations

N-cadherin switching occurs in high Gleason grade prostate cancer

Jaggi, M., Nazemi, T., Abrahams, N. A., Baker, J. J., Galich, A., Smith, L. M. & Balaji, K. C., Feb 1 2006, In : Prostate. 66, 2, p. 193-199 7 p.

Research output: Contribution to journalArticle

68 Scopus citations

Neoadjuvant treatment of pancreatic adenocarcinoma: A systematic review and meta-analysis of 5520 patients

Dhir, M., Malhotra, G. K., Sohal, D. P. S., Hein, N. A., Smith, L. M., O'Reilly, E. M., Bahary, N. & Are, C., Oct 10 2017, In : World Journal of Surgical Oncology. 15, 1, 183.

Research output: Contribution to journalArticle

40 Scopus citations

Neuropathologic and neuroinflammatory activities of HIV-1-infected human astrocytes in murine brain

Dou, H., Morehead, J., Bradley, J., Gorantla, S., Ellison, B., Kingsley, J., Smith, L. M., Chao, W., Bentsman, G., Volsky, D. J. & Gendelman, H. E., Aug 1 2006, In : Glia. 54, 2, p. 81-93 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Nomogram line crossing after acetaminophen combination product overdose

Kirschner, R. I., Rozier, C. M., Smith, L. M. & Jacobitz, K. L., Jan 2 2016, In : Clinical Toxicology. 54, 1, p. 40-46 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

No survival advantage exists for patients undergoing loop ileostomy for clostridium difficile colitis

Hall, B. R., Leinicke, J. A., Armijo, P. R., Smith, L. M., Langenfeld, S. J. & Oleynikov, D., Jan 2019, In : American journal of surgery. 217, 1, p. 34-39 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Oligonucleotide microarrays demonstrate the highest frequency of ATM mutations in the mantle cell subtype of lymphoma

Fang, N. Y., Greiner, T. C., Weisenburger, D. D., Chan, W. C., Vose, J. M., Smith, L. M., Armitage, J. O., Mayer, R. A., Pike, B. L., Collins, F. S. & Hacia, J. G., Apr 29 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 9, p. 5372-5377 6 p.

Research output: Contribution to journalArticle

80 Scopus citations

Omega-3 fatty acid intake by age, gender, and pregnancy status in the United States: National health and nutrition examination survey 2003–2014

Thompson, M., Hein, N., Hanson, C., Smith, L. M., Anderson-Berry, A., Richter, C. K., Bisselou, K. S., Appiah, A. K., Kris-Etherton, P., Skulas-Ray, A. C. & Nordgren, T. M., Jan 1 2019, In : Nutrients. 11, 1, 177.

Research output: Contribution to journalArticle

11 Scopus citations

Omega‐3 long‐chain polyunsaturated fatty acids intake by ethnicity, income, and education level in the United States: NHANES 2003–2014

Cave, C., Hein, N., Smith, L. M., Anderson‐berry, A., Richter, C. K., Bisselou, K. S., Appiah, A. K., Kris‐etherton, P., Skulas-Ray, A. C., Thompson, M., Nordgren, T. M., Hanson, C. & Thoene, M., Jul 2020, In : Nutrients. 12, 7, p. 1-13 13 p., 2045.

Research output: Contribution to journalArticle

Open Access

Organ dysfunction following stem cell transplantation: Relationship to plasma cytokine concentrations

McGuire, T. R., Bociek, G. R., Pavletic, S. Z., Hock, L., Lynch, J., Schneider, J., Hoie, E. B., Tarantolo, S. & Haire, W. D., 2001, In : Bone marrow transplantation. 28, 9, p. 889-893 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Outcome of newly diagnosed children and adolescents with localized lymphoblastic lymphoma treated on Children's Oncology Group trial A5971: A report from the Children's Oncology Group

Termuhlen, A. M., Smith, L. M., Perkins, S. L., Lones, M., Finlay, J. L., Weinstein, H., Gross, T. G. & Abromowitch, M., Dec 15 2012, In : Pediatric Blood and Cancer. 59, 7, p. 1229-1233 5 p.

Research output: Contribution to journalArticle

24 Scopus citations
19 Scopus citations

Overexpression of PD2 leads to increased tumorigenicity and metastasis in pancreatic ductal adenocarcinoma

Vaz, A. P., Deb, S., Rachagani, S., Dey, P., Muniyan, S., Lakshmanan, I., Karmakar, S., Smith, L., Johansson, S., Lele, S., Ouellette, M., Ponnusamy, M. P. & Batra, S. K., 2016, In : Oncotarget. 7, 3, p. 3317-3331 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pathobiological implications of MUC4 in non-small-cell lung cancer

Majhi, P. D., Lakshmanan, I., Ponnusamy, M. P., Jain, M., Das, S., Kaur, S., Shimizu, S. T., West, W. W., Johansson, S. L., Smith, L. M., Yu, F., Rolle, C. E., Sharma, P., Carey, G. B., Batra, S. K. & Ganti, A. K., Apr 2013, In : Journal of Thoracic Oncology. 8, 4, p. 398-407 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Patient outcome following 2 different stress imaging approaches: A prospective randomized comparison

Porter, T. R., Smith, L. M., Wu, J., Thomas, D., Haas, J. T., Mathers, D. H., Williams, E., Olson, J., Nalty, K., Hess, R., Therrien, S. & Xie, F., Jun 18 2013, In : Journal of the American College of Cardiology. 61, 24, p. 2446-2455 10 p.

Research output: Contribution to journalArticle

35 Scopus citations
54 Scopus citations

PC or PCV, that is the question: Primary anaplastic oligodendroglial tumors treated with procarbazine and CCNU with and without vincristine

Webre, C., Shonka, N., Smith, L., Liu, D. & De Groot, J., Oct 1 2015, In : Anticancer Research. 35, 10, p. 5467-5472 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Perfusion Treatment Algorithm: Methods of Improving the Quality of Perfusion

Holcomb, H. B., Stammers, A. H., Gao, C., Nutter, B., Ellis, T., Ahlgren, R. L., Schmer, R. G. & Hock, L. M., Dec 2003, In : Journal of Extra-Corporeal Technology. 35, 4, p. 290-296 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Phase I/II study of dasatinib and exploratory genomic analysis in relapsed or refractory non-Hodgkin lymphoma

Umakanthan, J. M., Iqbal, J., Batlevi, C. L., Bouska, A., Smith, L. M., Shostrom, V., Nutsch, H., William, B. M., Gregory Bociek, R., Lunning, M., Bierman, P., Younes, A., Armitage, J. O. & Vose, J. M., Mar 2019, In : British Journal of Haematology. 184, 5, p. 744-752 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Poisson cokriging as a generalized linear mixed model

Smith, L. M., Stroup, W. W. & Marx, D. B., Mar 2020, In : Spatial Statistics. 35, 100399.

Research output: Contribution to journalArticle

Open Access

Potentials of Plasma NGAL and MIC-1 as Biomarker(s) in the Diagnosis of Lethal Pancreatic Cancer

Kaur, S., Chakraborty, S., Baine, M. J., Mallya, K., Smith, L. M., Sasson, A., Brand, R., Guha, S., Jain, M., Wittel, U., Singh, S. K. & Batra, S. K., Feb 1 2013, In : PloS one. 8, 2, e55171.

Research output: Contribution to journalArticle

38 Scopus citations

Precision medicine and actionable alterations in lung cancer: A single institution experience

Mambetsariev, I., Wang, Y., Chen, C., Nadaf, S., Pharaon, R., Fricke, J., Amanam, I., Amini, A., Bild, A., Chu, P., Erhunmwunsee, L., Kim, J., Munu, J., Pillai, R., Raz, D., Sampath, S., Vora, L., Qiu, F., Smith, L., Batra, S. K. & 4 others, Massarelli, E., Koczywas, M., Reckamp, K. & Salgia, R., Feb 1 2020, In : PloS one. 15, 2, e0228188.

Research output: Contribution to journalArticle

Open Access

Predictive global trends in the incidence and mortality of pancreatic cancer based on geographic location, socio-economic status, and demographic shift

Are, C., Chowdhury, S., Ahmad, H., Ravipati, A., Song, T., Shrikandhe, S. & Smith, L., Nov 1 2016, In : Journal of Surgical Oncology. 114, 6, p. 736-742 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Pre-operative Nomogram to Predict Risk of Peri-operative Mortality following Liver Resections for Malignancy

Dhir, M., Smith, L. M., Ullrich, F., Leiphrakpam, P. D., Ly, Q. P., Sasson, A. R. & Are, C., 2010, In : Journal of Gastrointestinal Surgery. 14, 11, p. 1770-1781 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Preoperative nomogram to predict risk of perioperative mortality following pancreatic resections for malignancy

Are, C., Afuh, C., Ravipati, L., Sasson, A., Ullrich, F. & Smith, L., Dec 2009, In : Journal of Gastrointestinal Surgery. 13, 12, p. 2152-2162 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

Preoperative pulmonary function tests (PFTs) and outcomes from resected early stage non-small cell lung cancer (NSCLC)

Almquist, D., Khanal, N., Smith, L. & Ganti, A. K., May 2018, In : Anticancer Research. 38, 5, p. 2903-2907 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Preoperative Risk Factors for 30-Day Reoperation in Patients Undergoing Hepatic Resections for Malignancy

Douaiher, J., Hussain, T., Dhir, M., Smith, L. & Are, C., Sep 1 2017, In : Indian Journal of Surgical Oncology. 8, 3, p. 312-320 9 p.

Research output: Contribution to journalArticle

Preparation Time for Preclinical Pathology Educational Activities in Medical Schools: a Survey of Pathology Educators

Talmon, G., Smith, L. & Booth, S. J., Jun 1 2011, In : Medical Science Educator. 21, 2, p. 169-176 8 p.

Research output: Contribution to journalArticle

Prevalence and risk factors for voice problems among telemarketers

Jones, K., Sigmon, J., Hock, L., Nelson, E., Sullivan, M. & Ogren, F., 2002, In : Archives of Otolaryngology - Head and Neck Surgery. 128, 5, p. 571-577 7 p.

Research output: Contribution to journalArticle

Open Access
62 Scopus citations

Prognostic and therapeutic implications of NHERF1 expression and regulation in colorectal cancer

Leiphrakpam, P. D., Lazenby, A. J., Chowdhury, S., Smith, L. M., Mathiesen, M., Brattain, M. G., Wang, J., Black, J. D. & Are, C., Mar 1 2020, In : Journal of Surgical Oncology. 121, 3, p. 547-560 14 p.

Research output: Contribution to journalArticle

Prognostic factors influencing survival in patients with B-cell small lymphocytic lymphoma

Nola, M., Pavletic, S. Z., Weisenburger, D. D., Smith, L. M., Bast, M. A., Vose, J. M. & Armitage, J. O., Sep 2004, In : American Journal of Hematology. 77, 1, p. 31-35 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Prognostic factors of chronic graft-versus-host disease after allogeneic blood stem-cell transplantation

Pavletic, S. Z., Smith, L. M., Bishop, M. R., Lynch, J. C., Tarantolo, S. R., Vose, J. M., Bierman, P. J., Hadi, A., Armitage, J. O. & Kessinger, A., Apr 2005, In : American Journal of Hematology. 78, 4, p. 265-274 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Prospective randomized comparison of conventional stress echocardiography and real-time perfusion stress echocardiography in detecting significant coronary artery disease

Thomas, D., Xie, F., Smith, L. M., O'Leary, E., Smith, K., Olson, J., Nalty, K., Hess, R., Graham, M., Therrien, S. & Porter, T. R., Nov 2012, In : Journal of the American Society of Echocardiography. 25, 11, p. 1207-1214 8 p.

Research output: Contribution to journalArticle

11 Scopus citations