Paras Kumar Mishra, PhD

  • 1379 Citations
  • 23 h-Index
20052020

Research output per year

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Research Output

2020

MMP9 mediates acute hyperglycemia-induced human cardiac stem cell death by upregulating apoptosis and pyroptosis in vitro

Yadav, S. K., Kambis, T. N., Kar, S., Park, S. Y. & Mishra, P. K., Mar 1 2020, In : Cell Death and Disease. 11, 3, 186.

Research output: Contribution to journalArticle

Open Access
2019

Editorial: The Non-coding Genome and Cardiovascular Disease

Mishra, P. K. & Nemer, G., Jul 16 2019, In : Frontiers in Cardiovascular Medicine. 6, 98.

Research output: Contribution to journalEditorial

Open Access

Erratum: Guidelines for evaluating myocardial cell death (American Journal of Physiology - Heart and Circulatory Physiology (2019) 317 (H891-H922) DOI: 10.1152/ajpheart.00259.2019)

Mishra, P. K., Adameova, A., Hill, J. A., Baines, C. P., Kang, P. M., Downey, J. M., Narula, J., Takahashi, M., Abbate, A., Piristine, H. C., Kar, S., Su, S., Higa, J. K., Kawasaki, N. K. & Matsui, T., Dec 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 317, 6, p. H1390

Research output: Contribution to journalComment/debate

Open Access

Exercise training promotes cardiac hydrogen sulfide biosynthesis and mitigates pyroptosis to prevent high-fat diet-induced diabetic cardiomyopathy

Kar, S., Shahshahan, H. R., Hackfort, B. T., Yadav, S. K., Yadav, R., Kambis, T. N., Lefer, D. J. & Mishra, P. K., Dec 2019, In : Antioxidants. 8, 12, 638.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Guidelines for evaluating myocardial cell death

Mishra, P. K., Adameova, A., Hill, J. A., Baines, C. P., Kang, P. M., Downey, J. M., Narula, J., Takahashi, M., Abbate, A., Piristine, H. C., Kar, S., Su, S., Higa, J. K., Kawasaki, N. K. & Matsui, T., 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 317, 5, p. H891-H922

Research output: Contribution to journalReview article

Open Access
10 Scopus citations

Hydrogen sulfide ameliorates homocysteine-induced cardiac remodeling and dysfunction

Kar, S., Shahshahan, H. R., Kambis, T. N., Yadav, S. K., Li, Z., Lefer, D. J. & Mishra, P. K., 2019, In : Frontiers in Physiology. 10, MAY, 598.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
4 Scopus citations

Isolation, characterization, and differentiation of cardiac stem cells from the adult mouse heart

Yadav, S. K. & Mishra, P. K., Jan 2019, In : Journal of Visualized Experiments. 2019, 143, e58448.

Research output: Contribution to journalArticle

MTOR signaling in cardiometabolic disease, cancer, and aging 2018

Das, A., Reis, F. & Mishra, P. K., 2019, In : Oxidative medicine and cellular longevity. 2019, 9692528.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

Regulating inflammatory cytokines in the diabetic heart

Yadav, S. K., Kambis, T. N. & Mishra, P. K., Jan 1 2019, Oxidative Stress in Heart Diseases. Springer Singapore, p. 427-436 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Transgenic Expression of miR-133a in the Diabetic Akita Heart Prevents Cardiac Remodeling and Cardiomyopathy

Kambis, T. N., Shahshahan, H. R., Kar, S., Yadav, S. K. & Mishra, P. K., Apr 24 2019, In : Frontiers in Cardiovascular Medicine. 6, 45.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2018

Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice

Krishnan, B., Massilamany, C., Basavalingappa, R. H., Gangaplara, A., Rajasekaran, R. A., Afzal, M. Z., Khalilzad-Sharghi, V., Zhou, Y., Riethoven, J. J., Nandi, S. S., Mishra, P. K., Sobel, R. A., Strande, J. L., Steffen, D. & Reddy, J., Jan 15 2018, In : Journal of Immunology. 200, 2, p. 523-537 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Isolation, characterization and differentiation of mouse cardiac progenitor cells

Yadav, S. K. & Mishra, P. K., 2018, Methods in Molecular Biology. Humana Press Inc., p. 183-191 9 p. (Methods in Molecular Biology; vol. 1842).

Research output: Chapter in Book/Report/Conference proceedingChapter

MiR-133a mimic alleviates T1DM-induced systolic dysfunction in akita: An MRI-based study

Nandi, S. S., Shahshahan, H. R., Shang, Q., Kutty, S., Boska, M. & Mishra, P. K., Oct 10 2018, In : Frontiers in Physiology. 9, OCT, 1275.

Research output: Contribution to journalArticle

4 Scopus citations

Targeting miRNA for therapy of juvenile and adult diabetic cardiomyopathy

Nandi, S. S. & Mishra, P. K., 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 47-59 13 p. (Advances in Experimental Medicine and Biology; vol. 1056).

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
2017
7 Scopus citations

Cardiac transcriptome profiling of diabetic Akita mice using microarray and next generation sequencing

Kesherwani, V., Shahshahan, H. R. & Mishra, P. K., Aug 2017, In : PloS one. 12, 8, e0182828.

Research output: Contribution to journalArticle

11 Scopus citations

Diabetic cardiomyopathy: An immunometabolic perspective

Mishra, P. K., Ying, W., Nandi, S. S., Bandyopadhyay, G. K., Patel, K. K. & Mahata, S. K., Apr 7 2017, In : Frontiers in Endocrinology. 8, APR, 72.

Research output: Contribution to journalShort survey

26 Scopus citations
19 Scopus citations

Stem Cell-Derived Exosomes, Autophagy, Extracellular Matrix Turnover, and miRNAs in Cardiac Regeneration during Stem Cell Therapy

Prathipati, P., Nandi, S. S. & Mishra, P. K., Feb 1 2017, In : Stem Cell Reviews and Reports. 13, 1, p. 79-91 13 p.

Research output: Contribution to journalReview article

33 Scopus citations
2016

Ablation of matrix metalloproteinase-9 prevents cardiomyocytes contractile dysfunction in diabetics

Prathipati, P., Metreveli, N., Nandi, S. S., Tyagi, S. C. & Mishra, P. K., Mar 15 2016, In : Frontiers in Physiology. 7, MAR, 93.

Research output: Contribution to journalArticle

12 Scopus citations

Emerging role of hydrogen sulfide-microRNA crosstalk in cardiovascular diseases

Hackfort, B. T. & Mishra, P. K., Apr 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 310, 7, p. H802-H812

Research output: Contribution to journalReview article

20 Scopus citations

Lack of MIR-133a decreases contractility of diabetic hearts: A role for novel cross talk between tyrosine aminotransferase and tyrosine hydroxylase

Nandi, S. S., Zheng, H., Sharma, N. M., Shahshahan, H. R., Patel, K. P. & Mishra, P. K., Oct 1 2016, In : Diabetes. 65, 10, p. 3075-3090 16 p.

Research output: Contribution to journalArticle

18 Scopus citations
2015

Exercise ameliorates high fat diet induced cardiac dysfunction by increasing interleukin 10

Kesherwani, V., Chavali, V., Hackfort, B. T., Tyagi, S. C. & Mishra, P. K., 2015, In : Frontiers in Physiology. 6, APR, 124.

Research output: Contribution to journalArticle

23 Scopus citations

Hydrogen sulfide mitigates homocysteine-mediated pathological remodeling by inducing miR-133a in cardiomyocytes

Kesherwani, V., Nandi, S. S., Sharawat, S. K., Shahshahan, H. R. & Mishra, P. K., Jun 18 2015, In : Molecular and cellular biochemistry. 404, 1-2, p. 241-250 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
28 Scopus citations
2014
12 Scopus citations

Differential Expression of Dicer, miRNAs, and Inflammatory Markers in Diabetic Ins2+/- Akita Hearts

Chavali, V., Tyagi, S. C. & Mishra, P. K., Jan 2014, In : Cell Biochemistry and Biophysics. 68, 1, p. 25-35 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Generating double knockout mice to model genetic intervention for diabetic cardiomyopathy in humans

Chavali, V., Nandi, S. S. U., Singh, S. R. A. & Mishra, P. K. U., 2014, In : Methods in molecular biology (Clifton, N.J.). 1194, p. 385-400 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

MicroRNomics of diabetic cardiomyopathy

Mishra, P. K. & Tyagi, S. C., Jan 1 2014, Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms. Springer New York, p. 179-187 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2013

Cardiac matrix: A clue for future therapy

Mishra, P. K., Givvimani, S., Chavali, V. & Tyagi, S. C., Dec 2013, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1832, 12, p. 2271-2276 6 p.

Research output: Contribution to journalReview article

41 Scopus citations

Cardiac stem cell niche, mmp9, and culture and differentiation of embryonic stem cells

Mishra, P. K., Kuypers, N. J., Singh, S. R., Leiberh, N. D., Chavali, V. & Tyagi, S. C., 2013, Stem Cell Niche: Methods and Protocols. Humana Press Inc., p. 153-163 11 p. (Methods in Molecular Biology; vol. 1035).

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations

Predictors and prevention of diabetic cardiomyopathy

Chavali, V., Tyagi, S. C. & Mishra, P. K., Apr 10 2013, In : Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 6, p. 151-160 10 p.

Research output: Contribution to journalReview article

78 Scopus citations
2012
34 Scopus citations

Hydrogen sulfide mitigates cardiac remodeling during myocardial infarction via improvement of angiogenesis

Qipshidze, N., Metreveli, N., Mishra, P. K., Lominadze, D. & Tyagi, S. C., Feb 28 2012, In : International Journal of Biological Sciences. 8, 4, p. 430-441 12 p.

Research output: Contribution to journalArticle

63 Scopus citations

Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia

Sen, U., Sathnur, P. B., Kundu, S., Givvimani, S., Coley, D. M., Mishra, P. K., Qipshidze, N., Tyagi, N., Metreveli, N. & Tyagi, S. C., Jul 1 2012, In : American Journal of Physiology - Cell Physiology. 303, 1, p. C41-C51

Research output: Contribution to journalArticle

72 Scopus citations

MicroRNA-133a regulates DNA methylation in diabetic cardiomyocytes

Chavali, V., Tyagi, S. C. & Mishra, P. K., Aug 31 2012, In : Biochemical and Biophysical Research Communications. 425, 3, p. 668-672 5 p.

Research output: Contribution to journalArticle

36 Scopus citations
2011

Chronic hyperhomocysteinemia causes vascular remodelling by instigating vein phenotype in artery

Basu, P., Qipshidze, N., Sen, U., Givvimani, S., Munjal, C., Mishra, P. K. & Tyagi, S. C., Dec 2011, In : Archives of Physiology and Biochemistry. 117, 5, p. 270-282 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Exercise mitigates homocysteine - β2-adrenergic receptor interactions to ameliorate contractile dysfunction in diabetes

Mishra, P. K., Awe, O., Metreveli, N., Qipshidze, N., Joshua, I. G. & Tyagi, S. C., 2011, In : International Journal of Physiology, Pathophysiology and Pharmacology. 3, 2, p. 97-106 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Synergism between arrhythmia and hyperhomocysteinemia in structural heart disease

Givvimani, S., Qipshidze, N., Tyagi, N., Mishra, P. K., Sen, U. & Tyagi, S. C., 2011, In : International Journal of Physiology, Pathophysiology and Pharmacology. 3, 2, p. 107-119 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Synergy of microRNA and stem cell: A novel therapeutic approach for diabetes mellitus and cardiovascular diseases

Tyagi, A. C., Sen, U. & Mishra, P. K., Nov 2011, In : Current Diabetes Reviews. 7, 6, p. 367-376 10 p.

Research output: Contribution to journalReview article

24 Scopus citations
2010

Attenuation of beta2-adrenergic receptors and homocysteine metabolic enzymes cause diabetic cardiomyopathy

Mishra, P. K., Givvimani, S., Metreveli, N. & Tyagi, S. C., Oct 15 2010, In : Biochemical and Biophysical Research Communications. 401, 2, p. 175-181 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

H2S ameliorates oxidative and proteolytic stresses and protects the heart against adverse remodeling in chronic heart failure

Mishra, P. K., Tyagi, N., Sen, U., Givvimani, S. & Tyagi, S. C., 2010, In : American Journal of Physiology - Heart and Circulatory Physiology. 298, 2, p. H451-H456

Research output: Contribution to journalArticle

62 Scopus citations

Homocysteine to hydrogen sulfide or hypertension

Sen, U., Mishra, P. K., Tyagi, N. & Tyagi, S. C., 2010, In : Cell Biochemistry and Biophysics. 57, 2, p. 49-58 10 p.

Research output: Contribution to journalReview article

102 Scopus citations

MMP-2/TIMP-2/TIMP-4 versus MMP-9/TIMP-3 in transition from compensatory hypertrophy and angiogenesis to decompensatory heart failure

Givvimani, S., Tyagi, N., Sen, U., Mishra, P. K., Qipshidze, N., Munjal, C., Vacek, J. C., Abe, O. A. & Tyagi, S. C., May 2010, In : Archives of Physiology and Biochemistry. 116, 2, p. 63-72 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

MMP-9 gene ablation and TIMP-4 mitigate PAR-1-mediated cardiomyocyte dysfunction: A plausible role of dicer and miRNA

Mishra, P. K., Metreveli, N. & Tyagi, S. C., 2010, In : Cell Biochemistry and Biophysics. 57, 2, p. 67-76 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Stem cells as a therapeutic target for diabetes

Mishra, P. K., Singh, S. R., Joshua, I. G. & Tyagi, S. C., Jan 1 2010, In : Frontiers in Bioscience. 15, 2, p. 461-477 17 p.

Research output: Contribution to journalArticle

39 Scopus citations

Synergism in hyperhomocysteinemia and diabetes: Role of PPAR gamma and tempol

Mishra, P. K., Tyagi, N., Sen, U., Joshua, I. G. & Tyagi, S. C., Sep 9 2010, In : Cardiovascular Diabetology. 9, 49.

Research output: Contribution to journalArticle

47 Scopus citations
2009

Homocysteine, hydrogen sulfide (H2S) and NMDA-receptor in heart failure

Tyagi, N., Mishra, P. K. & Tyagi, S. C., Dec 1 2009, In : Indian journal of biochemistry & biophysics. 46, 6, p. 441-446 6 p.

Research output: Contribution to journalReview article

11 Scopus citations

Homocysteine effects classical pathway of GPCR down regulation: Gαq/11, Gα12/13, Gi/o

Vacek, T. P., Sen, U., Tyagi, N., Kumar, M., Moshal, K. S., Passmore, J. C. & Tyagi, S. C., 2009, In : Molecular and cellular biochemistry. 321, 1-2, p. 1-8 8 p.

Research output: Contribution to journalArticle

4 Scopus citations