Research output per year
Research output per year
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Dive into the research topics where Paul C Trippier is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
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AKR1C3 Inhibitors as Chemotherapeutic Potentiators
Trippier, P. C. (CoPI) & Trippier, P. C. (PI)
Project: Research project
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Development and Characterization of Peptidomimetic Small Molecule Activators of Peptidase Neurolysin for Stroke Therapy
Trippier, P. C. (CoPI) & Trippier, P. C. (CoPI)
Project: Research project
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UNMC Training Program in Alzheimer’s Disease and Related Dementias Drug Discovery
Trippier, P. C. (PI) & Fox, H. S. (CoPI)
Project: Research project
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Small Molecule Drug Discovery for CLN3 and CLN6 Disease
Trippier, P. C. (PI)
Project: Research project
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Coumarin-Based Aldo-Keto Reductase Family 1C (AKR1C) 2 and 3 Inhibitors
Jonnalagadda, S. K., Duan, L., Dow, L. F., Boligala, G. P., Kosmacek, E., McCoy, K., Oberley-Deegan, R., Chhonker, Y. S., Murry, D. J., Reynolds, C. P., Maurer, B. J., Penning, T. M. & Trippier, P. C., Nov 4 2024, In: ChemMedChem. 19, 21, e202400081.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of an Aldo-Keto reductase 1C3 (AKR1C3) degrader
Carmona, A. V., Jonnalagadda, S., Case, A. M., Maddeboina, K., Jonnalagadda, S. K., Dow, L. F., Duan, L., Penning, T. M. & Trippier, P. C., Dec 2024, In: Communications Chemistry. 7, 1, 95.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Imidazole Bioisostere Activators of Endopeptidase Neurolysin with Enhanced Potency and Metabolic Stability
Rahman, M. S., Hadi Esfahani, S., Zhang, Y., Queen, A., Aljarrah, M., Kandil, H., Baez, A., Abbruscato, T. J., Karamyan, V. T. & Trippier, P. C., Apr 11 2024, In: ACS Medicinal Chemistry Letters. 15, 4, p. 510-517 8 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
In vitro ADME, mouse pharmacokinetics of LD14b, and bioanalysis of a novel aβ 17β-HSD10 modulator for the treatment of Alzheimer’s disease
Daria, S., Kumar, D., Gautam, N., Alamoudi, J. A., Dow, L. F., Trippier, P. C. & Alnouti, Y., 2024, In: Xenobiotica. 54, 9, p. 711-722 12 p.Research output: Contribution to journal › Article › peer-review
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Synthesis and biological characterization of a 17β hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor
Dow, L. F., Pathirage, R., Erickson, H. E., Amani, E., Ronning, D. R. & Trippier, P. C., 2024, (Accepted/In press) In: RSC Medicinal Chemistry.Research output: Contribution to journal › Article › peer-review