Polina V Shcherbakova, PhD

Associate Professor, Eppley Institute for Cancer Research
Coordinator Genomic Instability Group, Eppley Institute for Cancer Research
Courtesy Associate Professor, Genetics, Cell Biology & Anatomy
Member, Fred & Pamela Buffett Cancer Center
Mentor, Center for Molecular Target Discovery & Development

Phone402-559-7694

Source: Scopus
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3 Finished

Mechanisms of Genome Instability in Tumors with DNA Polymerase Epsilon Mutations
Shcherbakova, P. V.
Project: Research project
Genome Instability and Human Diseases
Shcherbakova, P. V.
National Institutes of Health
5/1/13 → 4/30/14
Project: Research project
Translesion Synthesis DNA Polymerases and Genome Instability
Shcherbakova, P. V.
National Institutes of Health
7/1/07 → 2/28/19
Project: Research project
Role of DNA polymerases in chromosome stability control
Shcherbakova, P. V.
National Institutes of Health
9/1/03 → 6/30/07
Project: Research project

1606 Citations
26 h-Index
32 Article
6 Review article
1 Short survey

DNA polymerase δ proofreads errors made by DNA polymerase e
Bulock, C. R., Xing, X. & Shcherbakova, P. V., Mar 17 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 11, p. 6035-6041 7 p.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Scopus citations
Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorectal and Endometrial Tumors
Lee, M., Eng, G., Barbari, S. R., Deshpande, V., Shcherbakova, P. V. & Gala, M. K., Mar 1 2020, In: Clinical and translational gastroenterology. 11, 3, p. e00149
Research output: Contribution to journal › Article › peer-review

Open Access
Mismatch repair and DNA polymerase δproofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ϵ variant
Bulock, C. R., Xing, X. & Shcherbakova, P. V., Sep 18 2020, In: Nucleic acids research. 48, 16, p. 9124-9134 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme
Xing, X., Kane, D. P., Bulock, C. R., Moore, E. A., Sharma, S., Chabes, A. & Shcherbakova, P. V., Dec 1 2019, In: Nature communications. 10, 1, 374.
Research output: Contribution to journal › Article › peer-review
11 Scopus citations
Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase ε
Parkash, V., Kulkarni, Y., ter Beek, J., Shcherbakova, P. V., Kamerlin, S. C. L. & Johansson, E., Dec 1 2019, In: Nature communications. 10, 1, 373.
Research output: Contribution to journal › Article › peer-review
10 Scopus citations