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Dive into the research topics where Polina V Shcherbakova is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Mechanisms of Genome Instability in Tumors with DNA Polymerase Epsilon Mutations
Project: Research project
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Translesion Synthesis DNA Polymerases and Genome Instability
7/1/07 → 2/28/19
Project: Research project
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DNA polymerase δ proofreads errors made by DNA polymerase e
Bulock, C. R., Xing, X. & Shcherbakova, P. V., Mar 17 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 11, p. 6035-6041 7 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorectal and Endometrial Tumors
Lee, M., Eng, G., Barbari, S. R., Deshpande, V., Shcherbakova, P. V. & Gala, M. K., Mar 1 2020, In: Clinical and translational gastroenterology. 11, 3, p. e00149Research output: Contribution to journal › Article › peer-review
Open Access -
Mismatch repair and DNA polymerase δproofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ϵ variant
Bulock, C. R., Xing, X. & Shcherbakova, P. V., Sep 18 2020, In: Nucleic acids research. 48, 16, p. 9124-9134 11 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme
Xing, X., Kane, D. P., Bulock, C. R., Moore, E. A., Sharma, S., Chabes, A. & Shcherbakova, P. V., Dec 1 2019, In: Nature communications. 10, 1, 374.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase ε
Parkash, V., Kulkarni, Y., ter Beek, J., Shcherbakova, P. V., Kamerlin, S. C. L. & Johansson, E., Dec 1 2019, In: Nature communications. 10, 1, 373.Research output: Contribution to journal › Article › peer-review
12 Scopus citations