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Dive into the research topics where Polina V Shcherbakova is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Mechanisms of Genome Instability in Tumors with DNA Polymerase Epsilon Mutations
Shcherbakova, P. V. (PI)
Project: Research project
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Translesion synthesis DNA polymerases and genome instability
Shcherbakova, P. V. (PI)
Project: Research project
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Mechanisms of Genome Instability in Tumors with DNA Polymerase Epsilon Mutations
Shcherbakova, P. V. (PI)
Project: Research project
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Role of DNA polymerases in chromosome stability control
Shcherbakova, P. V. (PI)
Project: Research project
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DNA polymerase ε and δ variants drive mutagenesis in polypurine tracts in human tumors
Ostroverkhova, D., Tyryshkin, K., Beach, A. K., Moore, E. A., Masoudi-Sobhanzadeh, Y., Barbari, S. R., Rogozin, I. B., Shaitan, K. V., Panchenko, A. R. & Shcherbakova, P. V., Jan 23 2024, In: Cell Reports. 43, 1, 113655.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Enhanced polymerase activity permits efficient synthesis by cancer-Associated DNA polymerase variants at low dNTP levels
Barbari, S. R., Beach, A. K., Markgren, J. G., Parkash, V., Moore, E. A., Johansson, E. & Shcherbakova, P. V., Aug 12 2022, In: Nucleic acids research. 50, 14, p. 8023-8040 18 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Compensation for the absence of the catalytically active half of DNA polymerase ϵ in yeast by positively selected mutations in CDC28
Stepchenkova, E. I., Zhuk, A. S., Cui, J., Tarakhovskaya, E. R., Barbari, S. R., Shcherbakova, P. V., Polev, D. E., Fedorov, R., Poliakov, E., Rogozin, I. B., Lada, A. G. & Pavlov, Y. I., Jun 2021, In: Genetics. 218, 2, iyab060.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
DNA polymerase δ proofreads errors made by DNA polymerase e
Bulock, C. R., Xing, X. & Shcherbakova, P. V., Mar 17 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 11, p. 6035-6041 7 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorectal and Endometrial Tumors
Lee, M., Eng, G., Barbari, S. R., Deshpande, V., Shcherbakova, P. V. & Gala, M. K., Mar 1 2020, In: Clinical and translational gastroenterology. 11, 3, p. e00149Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations