• 7444 Citations
  • 49 h-Index
19952020

Research output per year

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Research Output

2020

ApoE mimetic peptide targeted nanoparticles carrying a BRD4 inhibitor for treating Medulloblastoma in mice

Wang, Q., Kumar, V., Lin, F., Sethi, B., Coulter, D. W., McGuire, T. R. & Mahato, R. I., Jul 10 2020, In : Journal of Controlled Release. 323, p. 463-474 12 p.

Research output: Contribution to journalArticle

Functional similarity of modified cascade impactor to deposit drug particles on cells

Kumar, V., Bariwal, J., Narang, A. S., Tso, J., Cheong, J. & Mahato, R. I., Jun 15 2020, In : International journal of pharmaceutics. 583, 1 p.

Research output: Contribution to journalArticle

2019

Design of Hedgehog pathway inhibitors for cancer treatment

Bariwal, J., Kumar, V., Dong, Y. & Mahato, R. I., May 2019, In : Medicinal Research Reviews. 39, 3, p. 1137-1204 68 p.

Research output: Contribution to journalReview article

6 Scopus citations

Dual responsive micelles capable of modulating miRNA-34a to combat taxane resistance in prostate cancer

Lin, F., Wen, D., Wang, X. & Mahato, R. I., Feb 2019, In : Biomaterials. 192, p. 95-108 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

Gene therapy

Wu, H., Chaudhary, A. K. & Mahato, R. I., Apr 13 2019, Pharmaceutical Biotechnology: Fundamentals and Applications. Springer International Publishing, p. 323-355 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nano-carriers for delivery and targeting of active ingredients of Chinese medicine for hepatocellular carcinoma therapy

Chen, M., Zhou, X., Chen, R., Wang, J., Ye, R. D., Wang, Y., Wu, C. & Mahato, R. I., May 2019, In : Materials Today. 25, p. 66-87 22 p.

Research output: Contribution to journalReview article

1 Scopus citations

Nanoparticulate delivery of potent microtubule inhibitor for metastatic melanoma treatment

Bariwal, J., Kumar, V., Chen, H., Bhattarai, R. S., Peng, Y., Li, W. & Mahato, R. I., Sep 10 2019, In : Journal of Controlled Release. 309, p. 231-243 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Polymeric micellar delivery of novel microtubule destabilizer and hedgehog signaling inhibitor for treating chemoresistant prostate cancer

Yang, R., Chen, H., Guo, D., Dong, Y., Miller, D. D., Li, W. & Mahato, R. I., 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 3, p. 864-875 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Roles of microRNAs in T cell immunity: Implications for strategy development against infectious diseases

Giri, B. R., Mahato, R. I. & Cheng, G., Mar 2019, In : Medicinal Research Reviews. 39, 2, p. 706-732 27 p.

Research output: Contribution to journalReview article

1 Scopus citations

ROS-Responsive Polymeric Micelles for Triggered Simultaneous Delivery of PLK1 Inhibitor/miR-34a and Effective Synergistic Therapy in Pancreatic Cancer

Xin, X., Lin, F., Wang, Q., Yin, L. & Mahato, R. I., Apr 24 2019, In : ACS Applied Materials and Interfaces. 11, 16, p. 14647-14659 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Self-assembling lisofylline-fatty acid conjugate for effective treatment of diabetes mellitus

Italiya, K. S., Mazumdar, S., Sharma, S., Chitkara, D., Mahato, R. I. & Mittal, A., Jan 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 15, 1, p. 175-187 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

The use of micelles to deliver potential hedgehog pathway inhibitor for the treatment of liver fibrosis

Kumar, V., Dong, Y., Kumar, V., Almawash, S. & Mahato, R. I., 2019, In : Theranostics. 9, 25, p. 7537-7555 19 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Cholesterol and Morpholine Grafted Cationic Amphiphilic Copolymers for miRNA-34a Delivery

Sharma, S., Mazumdar, S., Italiya, K. S., Date, T., Mahato, R. I., Mittal, A. & Chitkara, D., Jun 4 2018, In : Molecular Pharmaceutics. 15, 6, p. 2391-2402 12 p.

Research output: Contribution to journalArticle

8 Scopus citations
2 Scopus citations

Co-delivery of siAlox15 and sunitinib for reversing the new-onset of type 1 diabetes in non-obese diabetic mice

Peng, Y., Wen, D., Lin, F. & Mahato, R. I., Dec 28 2018, In : Journal of Controlled Release. 292, p. 1-12 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Impact of miRNA-mRNA Profiling and Their Correlation on Medulloblastoma Tumorigenesis

Kumar, V., Kumar, V., Chaudhary, A. K., Coulter, D. W., McGuire, T. & Mahato, R. I., Sep 7 2018, In : Molecular Therapy - Nucleic Acids. 12, p. 490-503 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Lipid-polymer hybrid nanocarriers for delivering cancer therapeutics

Date, T., Nimbalkar, V., Kamat, J., Mittal, A., Mahato, R. I. & Chitkara, D., Feb 10 2018, In : Journal of Controlled Release. 271, p. 60-73 14 p.

Research output: Contribution to journalReview article

20 Scopus citations

MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis

Su, Q., Kumar, V., Sud, N. & Mahato, R. I., Apr 2018, In : Advanced Drug Delivery Reviews. 129, p. 54-63 10 p.

Research output: Contribution to journalReview article

24 Scopus citations

Pharmacokinetics and biodistribution of polymeric micelles containing miRNA and small-molecule drug in orthotopic pancreatic tumor-bearing mice

Kumar, V., Mundra, V., Peng, Y., Wang, Y., Tan, C. & Mahato, R. I., 2018, In : Theranostics. 8, 15, p. 4033-4049 17 p.

Research output: Contribution to journalReview article

11 Scopus citations

The fourth annual BRDS on genome editing and silencing for precision medicines

Chaudhary, A. K., Bhattarai, R. S. & Mahato, R. I., Feb 1 2018, In : Drug Delivery and Translational Research. 8, 1, p. 266-272 7 p.

Research output: Contribution to journalArticle

Therapeutic Potential of OMe-PS-miR-29b1 for Treating Liver Fibrosis

Kumar, V., Kumar, V., Luo, J. & Mahato, R. I., Dec 5 2018, In : Molecular Therapy. 26, 12, p. 2798-2811 14 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Bioconjugate Therapeutics: Current Progress and Future Perspective

Li, F. & Mahato, R. I., May 1 2017, In : Molecular Pharmaceutics. 14, 5, p. 1321-1324 4 p.

Research output: Contribution to journalEditorial

7 Scopus citations

Biodistribution of Self-Assembling Polymer-Gemcitabine Conjugate after Systemic Administration into Orthotopic Pancreatic Tumor Bearing Mice

Kattel, K., Mondal, G., Lin, F., Kumar, V. & Mahato, R. I., May 1 2017, In : Molecular Pharmaceutics. 14, 5, p. 1365-1372 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Challenges and Recent Advances in Medulloblastoma Therapy

Kumar, V., Kumar, V., McGuire, T., Coulter, D. W., Sharp, J. G. & Mahato, R. I., Dec 2017, In : Trends in Pharmacological Sciences. 38, 12, p. 1061-1084 24 p.

Research output: Contribution to journalReview article

24 Scopus citations

Chemosensitization and inhibition of pancreatic cancer stem cell proliferation by overexpression of microRNA-205

Chaudhary, A. K., Mondal, G., Kumar, V., Kattel, K. & Mahato, R. I., Aug 28 2017, In : Cancer Letters. 402, p. 1-8 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Combination therapy of paclitaxel and cyclopamine polymer-drug conjugates to treat advanced prostate cancer

Yang, R., Mondal, G., Wen, D. & Mahato, R. I., Feb 1 2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 2, p. 391-401 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer

Kumar, V., Chaudhary, A. K., Dong, Y., Zhong, H. A., Mondal, G., Lin, F., Kumar, V. & Mahato, R. I., Dec 1 2017, In : Scientific reports. 7, 1, 1665.

Research output: Contribution to journalArticle

14 Scopus citations

EGFR-Targeted Cationic Polymeric Mixed Micelles for Codelivery of Gemcitabine and miR-205 for Treating Advanced Pancreatic Cancer

Mondal, G., Almawash, S., Chaudhary, A. K. & Mahato, R. I., Sep 5 2017, In : Molecular Pharmaceutics. 14, 9, p. 3121-3133 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Micellar delivery of miR-34a modulator rubone and paclitaxel in resistant prostate cancer

Wen, D., Peng, Y., Lin, F., Singh, R. K. & Mahato, R. I., Jun 15 2017, In : Cancer Research. 77, 12, p. 3244-3254 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Nanomedicines for the Treatment of CNS Diseases

Reynolds, J. L. & Mahato, R. I., Mar 1 2017, In : Journal of Neuroimmune Pharmacology. 12, 1

Research output: Contribution to journalArticle

14 Scopus citations

Non-viral delivery of nucleic acid complexes

Kumar, V., Wen, D. & Mahato, R. I., Jan 1 2017, Comprehensive Biomaterials II. Elsevier, p. 506-526 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pharmaceutical dosage forms and drug delivery, third edition: Revised and expanded

Mahato, R. I. & Narang, A. S., Jan 1 2017, CRC Press. 690 p.

Research output: Book/ReportBook

4 Scopus citations

Pharmacokinetics and Biodistribution of GDC-0449 Loaded Micelles in Normal and Liver Fibrotic Mice

Dutta, R., Kumar, V., Peng, Y., Evande, R. E., Grem, J. L. & Mahato, R. I., Mar 1 2017, In : Pharmaceutical Research. 34, 3, p. 564-578 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

Polymer conjugate of a microtubule destabilizer inhibits lung metastatic melanoma

Yang, R., Mondal, G., Ness, R. A., Arnst, K., Mundra, V., Miller, D. D., Li, W. & Mahato, R. I., Mar 10 2017, In : Journal of Controlled Release. 249, p. 32-41 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Recent advances in hepatocellular carcinoma therapy

Dutta, R. & Mahato, R. I., May 1 2017, In : Pharmacology and Therapeutics. 173, p. 106-117 12 p.

Research output: Contribution to journalReview article

101 Scopus citations

The third annual BRDS on research and development of nucleic acid-based nanomedicines

Chaudhary, A. K. & Mahato, R. I., Feb 1 2017, In : Drug Delivery and Translational Research. 7, 1, p. 188-193 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Co-delivery of small molecule hedgehog inhibitor and miRNA for treating liver fibrosis

Kumar, V., Mondal, G., Dutta, R. & Mahato, R. I., 2016, In : Biomaterials. 76, p. 144-156 13 p.

Research output: Contribution to journalArticle

29 Scopus citations

EGFR-Targeted Polymeric Mixed Micelles Carrying Gemcitabine for Treating Pancreatic Cancer

Mondal, G., Kumar, V., Shukla, S. K., Singh, P. K. & Mahato, R. I., Jan 11 2016, In : Biomacromolecules. 17, 1, p. 301-313 13 p.

Research output: Contribution to journalArticle

21 Scopus citations

Mesenchymal stem cell and derived exosome as small RNA carrier and Immunomodulator to improve islet transplantation

Wen, D., Peng, Y., Liu, D., Weizmann, Y. & Mahato, R. I., Sep 28 2016, In : Journal of Controlled Release. 238, p. 166-175 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Micelle Mixtures for Coadministration of Gemcitabine and GDC-0449 to Treat Pancreatic Cancer

Karaca, M., Dutta, R., Ozsoy, Y. & Mahato, R. I., Jun 6 2016, In : Molecular Pharmaceutics. 13, 6, p. 1822-1832 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pharmacogenomics of neurodegenerative diseases: Roles in personalized medicines

Evande, R. E., Dutta, R., Tan, C., Grem, J. L. & Mahato, R. I., Jan 1 2016, Neuroimmune Pharmacology. Springer International Publishing, p. 959-970 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

Codelivery of small molecule hedgehog inhibitor and miRNA for treating pancreatic cancer

Kumar, V., Mondal, G., Slavik, P., Rachagani, S., Batra, S. K. & Mahato, R. I., Apr 6 2015, In : Molecular Pharmaceutics. 12, 4, p. 1289-1298 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Delivery and targeting of miRNAs for treating liver fibrosis

Kumar, V. & Mahato, R. I., Feb 2015, In : Pharmaceutical Research. 32, 2, p. 341-361 21 p.

Research output: Contribution to journalReview article

22 Scopus citations

Impact of CYP2C19 polymorphism on the pharmacokinetics of nelfinavir in patients with pancreatic cancer

Kattel, K., Evande, R., Tan, C., Mondal, G., Grem, J. L. & Mahato, R. I., Aug 1 2015, In : British Journal of Clinical Pharmacology. 80, 2, p. 267-275 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Micellar formulation of indocyanine green for phototherapy of melanoma

Mundra, V., Peng, Y., Rana, S., Natarajan, A. & Mahato, R. I., Dec 28 2015, In : Journal of Controlled Release. 220, p. 130-140 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

MiRNAs as targets for cancer treatment: Therapeutics design and delivery

Li, F. & Mahato, R. I., Jan 1 2015, In : Advanced Drug Delivery Reviews. 81, p. v-vi

Research output: Contribution to journalEditorial

5 Scopus citations

MiRNAs in pancreatic cancer: Therapeutic potential, delivery challenges and strategies

Chitkara, D., Mittal, A. & Mahato, R. I., Jan 1 2015, In : Advanced Drug Delivery Reviews. 81, p. 34-52 19 p.

Research output: Contribution to journalReview article

48 Scopus citations

Nanoparticle-mediated drug delivery for treating melanoma

Mundra, V., Li, W. & Mahato, R. I., Aug 1 2015, In : Nanomedicine. 10, 16, p. 2613-2633 21 p.

Research output: Contribution to journalReview article

26 Scopus citations

Small molecules targeting microRNA for cancer therapy: Promises and obstacles

Wen, D., Danquah, M., Chaudhary, A. K. & Mahato, R. I., Dec 10 2015, In : Journal of Controlled Release. 219, p. 237-247 11 p.

Research output: Contribution to journalReview article

43 Scopus citations
6 Scopus citations