• 7444 Citations
  • 49 h-Index
19952020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2020

ApoE mimetic peptide targeted nanoparticles carrying a BRD4 inhibitor for treating Medulloblastoma in mice

Wang, Q., Kumar, V., Lin, F., Sethi, B., Coulter, D. W., McGuire, T. R. & Mahato, R. I., Jul 10 2020, In : Journal of Controlled Release. 323, p. 463-474 12 p.

Research output: Contribution to journalArticle

Functional similarity of modified cascade impactor to deposit drug particles on cells

Kumar, V., Bariwal, J., Narang, A. S., Tso, J., Cheong, J. & Mahato, R. I., Jun 15 2020, In : International journal of pharmaceutics. 583, 1 p.

Research output: Contribution to journalArticle

2019

Dual responsive micelles capable of modulating miRNA-34a to combat taxane resistance in prostate cancer

Lin, F., Wen, D., Wang, X. & Mahato, R. I., Feb 2019, In : Biomaterials. 192, p. 95-108 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

Nanoparticulate delivery of potent microtubule inhibitor for metastatic melanoma treatment

Bariwal, J., Kumar, V., Chen, H., Bhattarai, R. S., Peng, Y., Li, W. & Mahato, R. I., Sep 10 2019, In : Journal of Controlled Release. 309, p. 231-243 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Polymeric micellar delivery of novel microtubule destabilizer and hedgehog signaling inhibitor for treating chemoresistant prostate cancer

Yang, R., Chen, H., Guo, D., Dong, Y., Miller, D. D., Li, W. & Mahato, R. I., 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 3, p. 864-875 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

ROS-Responsive Polymeric Micelles for Triggered Simultaneous Delivery of PLK1 Inhibitor/miR-34a and Effective Synergistic Therapy in Pancreatic Cancer

Xin, X., Lin, F., Wang, Q., Yin, L. & Mahato, R. I., Apr 24 2019, In : ACS Applied Materials and Interfaces. 11, 16, p. 14647-14659 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Self-assembling lisofylline-fatty acid conjugate for effective treatment of diabetes mellitus

Italiya, K. S., Mazumdar, S., Sharma, S., Chitkara, D., Mahato, R. I. & Mittal, A., Jan 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 15, 1, p. 175-187 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

The use of micelles to deliver potential hedgehog pathway inhibitor for the treatment of liver fibrosis

Kumar, V., Dong, Y., Kumar, V., Almawash, S. & Mahato, R. I., 2019, In : Theranostics. 9, 25, p. 7537-7555 19 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Cholesterol and Morpholine Grafted Cationic Amphiphilic Copolymers for miRNA-34a Delivery

Sharma, S., Mazumdar, S., Italiya, K. S., Date, T., Mahato, R. I., Mittal, A. & Chitkara, D., Jun 4 2018, In : Molecular Pharmaceutics. 15, 6, p. 2391-2402 12 p.

Research output: Contribution to journalArticle

8 Scopus citations
2 Scopus citations

Co-delivery of siAlox15 and sunitinib for reversing the new-onset of type 1 diabetes in non-obese diabetic mice

Peng, Y., Wen, D., Lin, F. & Mahato, R. I., Dec 28 2018, In : Journal of Controlled Release. 292, p. 1-12 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Impact of miRNA-mRNA Profiling and Their Correlation on Medulloblastoma Tumorigenesis

Kumar, V., Kumar, V., Chaudhary, A. K., Coulter, D. W., McGuire, T. & Mahato, R. I., Sep 7 2018, In : Molecular Therapy - Nucleic Acids. 12, p. 490-503 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

The fourth annual BRDS on genome editing and silencing for precision medicines

Chaudhary, A. K., Bhattarai, R. S. & Mahato, R. I., Feb 1 2018, In : Drug Delivery and Translational Research. 8, 1, p. 266-272 7 p.

Research output: Contribution to journalArticle

Therapeutic Potential of OMe-PS-miR-29b1 for Treating Liver Fibrosis

Kumar, V., Kumar, V., Luo, J. & Mahato, R. I., Dec 5 2018, In : Molecular Therapy. 26, 12, p. 2798-2811 14 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Biodistribution of Self-Assembling Polymer-Gemcitabine Conjugate after Systemic Administration into Orthotopic Pancreatic Tumor Bearing Mice

Kattel, K., Mondal, G., Lin, F., Kumar, V. & Mahato, R. I., May 1 2017, In : Molecular Pharmaceutics. 14, 5, p. 1365-1372 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Chemosensitization and inhibition of pancreatic cancer stem cell proliferation by overexpression of microRNA-205

Chaudhary, A. K., Mondal, G., Kumar, V., Kattel, K. & Mahato, R. I., Aug 28 2017, In : Cancer Letters. 402, p. 1-8 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Combination therapy of paclitaxel and cyclopamine polymer-drug conjugates to treat advanced prostate cancer

Yang, R., Mondal, G., Wen, D. & Mahato, R. I., Feb 1 2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 2, p. 391-401 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer

Kumar, V., Chaudhary, A. K., Dong, Y., Zhong, H. A., Mondal, G., Lin, F., Kumar, V. & Mahato, R. I., Dec 1 2017, In : Scientific reports. 7, 1, 1665.

Research output: Contribution to journalArticle

14 Scopus citations

EGFR-Targeted Cationic Polymeric Mixed Micelles for Codelivery of Gemcitabine and miR-205 for Treating Advanced Pancreatic Cancer

Mondal, G., Almawash, S., Chaudhary, A. K. & Mahato, R. I., Sep 5 2017, In : Molecular Pharmaceutics. 14, 9, p. 3121-3133 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Micellar delivery of miR-34a modulator rubone and paclitaxel in resistant prostate cancer

Wen, D., Peng, Y., Lin, F., Singh, R. K. & Mahato, R. I., Jun 15 2017, In : Cancer Research. 77, 12, p. 3244-3254 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Nanomedicines for the Treatment of CNS Diseases

Reynolds, J. L. & Mahato, R. I., Mar 1 2017, In : Journal of Neuroimmune Pharmacology. 12, 1

Research output: Contribution to journalArticle

14 Scopus citations

Pharmacokinetics and Biodistribution of GDC-0449 Loaded Micelles in Normal and Liver Fibrotic Mice

Dutta, R., Kumar, V., Peng, Y., Evande, R. E., Grem, J. L. & Mahato, R. I., Mar 1 2017, In : Pharmaceutical Research. 34, 3, p. 564-578 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

Polymer conjugate of a microtubule destabilizer inhibits lung metastatic melanoma

Yang, R., Mondal, G., Ness, R. A., Arnst, K., Mundra, V., Miller, D. D., Li, W. & Mahato, R. I., Mar 10 2017, In : Journal of Controlled Release. 249, p. 32-41 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

The third annual BRDS on research and development of nucleic acid-based nanomedicines

Chaudhary, A. K. & Mahato, R. I., Feb 1 2017, In : Drug Delivery and Translational Research. 7, 1, p. 188-193 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Co-delivery of small molecule hedgehog inhibitor and miRNA for treating liver fibrosis

Kumar, V., Mondal, G., Dutta, R. & Mahato, R. I., 2016, In : Biomaterials. 76, p. 144-156 13 p.

Research output: Contribution to journalArticle

29 Scopus citations

EGFR-Targeted Polymeric Mixed Micelles Carrying Gemcitabine for Treating Pancreatic Cancer

Mondal, G., Kumar, V., Shukla, S. K., Singh, P. K. & Mahato, R. I., Jan 11 2016, In : Biomacromolecules. 17, 1, p. 301-313 13 p.

Research output: Contribution to journalArticle

21 Scopus citations

Mesenchymal stem cell and derived exosome as small RNA carrier and Immunomodulator to improve islet transplantation

Wen, D., Peng, Y., Liu, D., Weizmann, Y. & Mahato, R. I., Sep 28 2016, In : Journal of Controlled Release. 238, p. 166-175 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Micelle Mixtures for Coadministration of Gemcitabine and GDC-0449 to Treat Pancreatic Cancer

Karaca, M., Dutta, R., Ozsoy, Y. & Mahato, R. I., Jun 6 2016, In : Molecular Pharmaceutics. 13, 6, p. 1822-1832 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
2015

Codelivery of small molecule hedgehog inhibitor and miRNA for treating pancreatic cancer

Kumar, V., Mondal, G., Slavik, P., Rachagani, S., Batra, S. K. & Mahato, R. I., Apr 6 2015, In : Molecular Pharmaceutics. 12, 4, p. 1289-1298 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Impact of CYP2C19 polymorphism on the pharmacokinetics of nelfinavir in patients with pancreatic cancer

Kattel, K., Evande, R., Tan, C., Mondal, G., Grem, J. L. & Mahato, R. I., Aug 1 2015, In : British Journal of Clinical Pharmacology. 80, 2, p. 267-275 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Micellar formulation of indocyanine green for phototherapy of melanoma

Mundra, V., Peng, Y., Rana, S., Natarajan, A. & Mahato, R. I., Dec 28 2015, In : Journal of Controlled Release. 220, p. 130-140 11 p.

Research output: Contribution to journalArticle

32 Scopus citations
6 Scopus citations

Systemic delivery of nanoparticle formulation of novel tubulin inhibitor for treating metastatic melanoma

Mundra, V., Peng, Y., Kumar, V., Li, W., Miller, D. D. & Mahato, R. I., Jun 1 2015, In : Drug Delivery and Translational Research. 5, 3, p. 199-208 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Core-shell nanoparticulate formulation of gemcitabine: lyophilization, stability studies, and in vivo evaluation

Chitkara, D., Mittal, A., Mahato, R. I. & Kumar, N., Nov 18 2014, In : Drug Delivery and Translational Research. 4, 5-6, p. 439-451 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Doxorubicin and lapatinib combination nanomedicine for treating resistant breast cancer

Wang, H., Li, F., Du, C., Wang, H., Mahato, R. I. & Huang, Y., Aug 4 2014, In : Molecular Pharmaceutics. 11, 8, p. 2600-2611 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Efficacy of gemcitabine conjugated and miRNA-205 complexed micelles for treatment of advanced pancreatic cancer

Mittal, A., Chitkara, D., Behrman, S. W. & Mahato, R. I., Aug 2014, In : Biomaterials. 35, 25, p. 7077-7087 11 p.

Research output: Contribution to journalArticle

73 Scopus citations

LHRH-conjugated micelles for targeted delivery of antiandrogen to treat advanced prostate cancer

Wen, D., Chitkara, D., Wu, H., Danquah, M., Patil, R., Miller, D. D. & Mahato, R. I., May 2 2014, In : Pharmaceutical Research. 31, 10, p. 2784-2795 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Mesenchymal stem cell-based therapy for type 1 diabetes

Wu, H. & Mahato, R. I., 2014, In : Discovery Medicine. 17, 93, p. 139-143 5 p.

Research output: Contribution to journalArticle

36 Scopus citations

Nanomedicines of hedgehog inhibitor and PPAR-γ agonist for treating liver fibrosis

Kumar, V., Mundra, V. & Mahato, R. I., May 2014, In : Pharmaceutical Research. 31, 5, p. 1158-1169 12 p.

Research output: Contribution to journalArticle

37 Scopus citations
2013

Effect of PEGylation on biodistribution and gene silencing of siRNA/lipid nanoparticle complexes

Bao, Y., Jin, Y., Chivukula, P., Zhang, J., Liu, Y., Liu, J., Clamme, J. P., Mahato, R. I., Ng, D., Ying, W., Wang, Y. & Yu, L., Feb 2013, In : Pharmaceutical Research. 30, 2, p. 342-351 10 p.

Research output: Contribution to journalArticle

47 Scopus citations
Open Access
12 Scopus citations

Lactic acid- and carbonate-based crosslinked polymeric micelles for drug delivery

Danquah, M., Fujiwara, T. & Mahato, R. I., Jan 15 2013, In : Journal of Polymer Science, Part A: Polymer Chemistry. 51, 2, p. 347-362 16 p.

Research output: Contribution to journalArticle

25 Scopus citations

Mesenchymal stem cell-based therapy

Mundra, V., Gerling, I. C. & Mahato, R. I., Jan 7 2013, In : Molecular Pharmaceutics. 10, 1, p. 77-89 13 p.

Research output: Contribution to journalArticle

78 Scopus citations

MiRNA profiling in pancreatic cancer and restoration of chemosensitivity

Singh, S., Chitkara, D., Kumar, V., Behrman, S. W. & Mahato, R. I., Jul 1 2013, In : Cancer Letters. 334, 2, p. 211-220 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Self-assembling, amphiphilic polymer-gemcitabine conjugate shows enhanced antitumor efficacy against human pancreatic adenocarcinoma

Chitkara, D., Mittal, A., Behrman, S. W., Kumar, N. & Mahato, R. I., Jul 17 2013, In : Bioconjugate Chemistry. 24, 7, p. 1161-1173 13 p.

Research output: Contribution to journalArticle

58 Scopus citations

Synthesis and characterization of an anti-apoptotic immunosuppressive compound for improving the outcome of islet transplantation

Wu, H., Pagadala, J., Yates, C. R., Miller, D. & Mahato, R. I., Dec 18 2013, In : Bioconjugate Chemistry. 24, 12, p. 2036-2044 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Third-party mesenchymal stem cells improved human islet transplantation in a humanized diabetic mouse model

Wu, H., Wen, D. & Mahato, R. I., Sep 2013, In : Molecular Therapy. 21, 9, p. 1778-1786 9 p.

Research output: Contribution to journalArticle

36 Scopus citations
2012

Attenuation of early liver fibrosis by pharmacological inhibition of smoothened receptor signaling

Pratap, A., Singh, S., Mundra, V., Yang, N., Panakanti, R., Eason, J. D. & Mahato, R. I., Nov 2012, In : Journal of Drug Targeting. 20, 9, p. 770-782 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway

Singh, S., Chitkara, D., Mehrazin, R., Behrman, S. W., Wake, R. W. & Mahato, R. I., Jun 29 2012, In : PloS one. 7, 6, e40021.

Research output: Contribution to journalArticle

86 Scopus citations

Combination therapy of antiandrogen and XIAP inhibitor for treating advanced prostate cancer

Danquah, M., Duke, C. B., Patil, R., Miller, D. D. & Mahato, R. I., Aug 2012, In : Pharmaceutical Research. 29, 8, p. 2079-2091 13 p.

Research output: Contribution to journalArticle

21 Scopus citations