• 1087 Citations
  • 20 h-Index
20012020

Research output per year

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Research Output

  • 1087 Citations
  • 20 h-Index
  • 45 Article
  • 2 Editorial
  • 2 Review article
2001

Effects of surfactant protein A and NaCl concentration on the uptake of Pseudomonas aeruginosa by THP-1 cells

Khubchandani, K. R., Oberley, R. E. & Snyder, J. M., 2001, In : American journal of respiratory cell and molecular biology. 25, 6, p. 699-706 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2003
31 Scopus citations
2004

Surfactant protein D is present in the human female reproductive tract and inhibits Chlamydia trachomatis infection

Oberley, R. E., Goss, K. L., Ault, K. A., Crouch, E. C. & Snyder, J. M., Dec 2004, In : Molecular Human Reproduction. 10, 12, p. 861-870 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Surfactant proteins A and D enhance the phagocytosis of Chlamydia into THP-1 cells

Oberley, R. E., Ault, K. A., Neff, T. L., Khubchandani, K. R., Crouch, E. C. & Snyder, J. M., Aug 2004, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 287, 2 31-2, p. L296-L306

Research output: Contribution to journalArticle

28 Scopus citations
2005

A role for surfactant protein D in innate immunity of the human prostate

Oberley, R. E., Goss, K. L., Dahmoush, L., Ault, K. A., Crouch, E. C. & Snyder, J. M., Nov 1 2005, In : Prostate. 65, 3, p. 241-251 11 p.

Research output: Contribution to journalArticle

26 Scopus citations
2007

A new tool to investigate differences between human SP-A1 and SP-A2

Oberley, R. E., George, C. L. S. & Snyder, J. M., May 2007, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 292, 5, p. L1050-L1051

Research output: Contribution to journalEditorial

4 Scopus citations

Regulation of surfactant protein D in the mouse female reproductive tract in vivo

Oberley, R. E., Goss, K. L., Hoffmann, D. S., Ault, K. A., Neff, T. L., Ramsey, K. H. & Snyder, J. M., Dec 2007, In : Molecular Human Reproduction. 13, 12, p. 863-868 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Regulation of surfactant protein D in the rodent prostate

Oberley, R. E., Goss, K. L., Quintar, A. A., Maldonado, C. A. & Snyder, J. M., Nov 7 2007, In : Reproductive Biology and Endocrinology. 5, 42.

Research output: Contribution to journalArticle

15 Scopus citations
2008

Surfactant protein D is expressed and modulates inflammatory responses in human coronary artery smooth muscle cells

Snyder, G. D., Oberley-Deegan, R. E., Goss, K. L., Romig-Martin, S. A., Stoll, L. L., Snyder, J. M. & Weintraub, N. L., May 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 294, 5, p. H2053-H2059

Research output: Contribution to journalArticle

28 Scopus citations
2009

Differentiated human alveolar type II cells secrete antiviral IL-29 (IFN-λ1) in response to influenza a infection

Wang, J., Oberley-Deegan, R., Wang, S., Nikrad, M., Funk, C. J., Hartshorn, K. L. & Mason, R. J., Feb 1 2009, In : Journal of Immunology. 182, 3, p. 1296-1304 9 p.

Research output: Contribution to journalArticle

Open Access
126 Scopus citations

Extracellular superoxide dismutase and risk of COPD

Oberley-Deegan, R. E., Regan, E. A., Kinnula, V. L. & Crapo, J. D., 2009, In : COPD: Journal of Chronic Obstructive Pulmonary Disease. 6, 4, p. 307-312 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

The antioxidant mimetic, MnTE-2-PyP, reduces intracellular growth of Mycobacterium abscessus

Oberley-Deegan, R. E., Young, M. L., Morey, G. E., Cook, D. M., Chan, E. D. & Crapo, J. D., Aug 1 2009, In : American journal of respiratory cell and molecular biology. 41, 2, p. 170-178 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2010

An oxidative environment promotes growth of Mycobacterium abscessus

Oberley-Deegan, R. E., Rebits, B. W., Weaver, M. R., Tollefson, A. K., Bai, X., McGibney, M., Ovrutsky, A. R., Chan, E. D. & Crapo, J. D., Dec 1 2010, In : Free Radical Biology and Medicine. 49, 11, p. 1666-1673 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress

Tollefson, A. K., Oberley-Deegan, R. E., Butterfield, K. T., Nicks, M. E., Weaver, M. R., Remigio, L. K., Decsesznak, J., Chu, H. W., Bratton, D. L., Riches, D. W. & Bowler, R. P., Dec 15 2010, In : Free Radical Biology and Medicine. 49, 12, p. 1937-1946 10 p.

Research output: Contribution to journalArticle

35 Scopus citations
2011

Antioxidant proteins and reactive oxygen species are decreased in a murine epidermal side population with stem cell-like characteristics

Carr, W. J., Oberley-Deegan, R. E., Zhang, Y., Oberley, C. C., Oberley, L. W. & Dunnwald, M., Mar 2011, In : Histochemistry and Cell Biology. 135, 3, p. 293-304 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Cigarette smoke increases susceptibility to tuberculosis-evidence from in vivo and in vitro models

Shang, S., Ordway, D., Henao-Tamayo, M., Bai, X., Oberley-Deegan, R., Shanley, C., Orme, I. M., Case, S., Minor, M., Ackart, D., Hascall-Dove, L., Ovrutsky, A. R., Kandasamy, P., Voelker, D. R., Lambert, C., Freed, B. M., Iseman, M. D., Basaraba, R. J. & Chan, E. D., May 1 2011, In : Journal of Infectious Diseases. 203, 9, p. 1240-1248 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury

Janssen, W. J., Barthel, L., Muldrow, A., Oberley-Deegan, R. E., Kearns, M. T., Jakubzick, C. & Henson, P. M., Sep 1 2011, In : American Journal of Respiratory and Critical Care Medicine. 184, 5, p. 547-560 14 p.

Research output: Contribution to journalArticle

160 Scopus citations

IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease

Bai, X., Ovrutsky, A. R., Kartalija, M., Chmura, K., Kamali, A., Honda, J. R., Oberley-deegan, R. E., Dinarello, C. A., Crapo, J. D., Chang, L. Y. & Chan, E. D., Nov 2011, In : International Immunology. 23, 11, p. 679-691 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

Mycobacterium tuberculosis increases IP-10 and MIG protein despite inhibition of IP-10 and MIG transcription

Bai, X., Chmura, K., Ovrutsky, A. R., Bowler, R. P., Scheinman, R. I., Oberley-Deegan, R. E., Liu, H., Shang, S., Ordway, D. & Chan, E. D., Jan 2011, In : Tuberculosis. 91, 1, p. 26-35 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2012

The Antioxidant, MnTE-2-PyP, Prevents Side-Effects Incurred by Prostate Cancer Irradiation

Oberley-Deegan, R. E., Steffan, J. J., Rove, K. O., Pate, K. M., Weaver, M. W., Spasojevic, I., Frederick, B., Raben, D., Meacham, R. B., Crapo, J. D. & Koul, H. K., Sep 12 2012, In : PloS one. 7, 9, e44178.

Research output: Contribution to journalArticle

30 Scopus citations

The metalloporphyrin antioxidant, MnTE-2-PyP, inhibits Th2 cell immune responses in an asthma model

Jungsuwadee, P., Weaver, M. R., Gally, F. & Oberley-Deegan, R. E., Aug 2012, In : International journal of molecular sciences. 13, 8, p. 9785-9797 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
2013

FABP5 deficiency enhances susceptibility to H1N1 influenza a virus-induced lung inflammation

Gally, F., Kosmider, B., Weaver, M. R., Pate, K. M., Hartshorn, K. L. & Oberley-Deegan, R. E., Jul 1 2013, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 305, 1, p. L64-L72

Research output: Contribution to journalArticle

20 Scopus citations

Inhibition of Nuclear Factor-Kappa B Activation Decreases Survival of Mycobacterium tuberculosis in Human Macrophages

Bai, X., Feldman, N. E., Chmura, K., Ovrutsky, A. R., Su, W. L., Griffin, L., Pyeon, D., McGibney, M. T., Strand, M. J., Numata, M., Murakami, S., Gaido, L., Honda, J. R., Kinney, W. H., Oberley-Deegan, R. E., Voelker, D. R., Ordway, D. J. & Chan, E. D., Apr 25 2013, In : PloS one. 8, 4, e61925.

Research output: Contribution to journalArticle

38 Scopus citations

Superoxide dismutase mimetic, MnTE-2-PyP, attenuates chronic hypoxia-induced pulmonary hypertension, pulmonary vascular remodeling, and activation of the NALP3 inflammasome

Villegas, L. R., Kluck, D., Field, C., Oberley-Deegan, R. E., Woods, C., Yeager, M. E., El Kasmi, K. C., Savani, R. C., Bowler, R. P. & Nozik-Grayck, E., May 10 2013, In : Antioxidants and Redox Signaling. 18, 14, p. 1753-1764 12 p.

Research output: Contribution to journalReview article

42 Scopus citations
2014

A common polymorphism in extracellular superoxide dismutase affects cardiopulmonary disease risk by altering protein distribution

Hartney, J. M., Stidham, T., Goldstrohm, D. A., Oberley-Deegan, R. E., Weaver, M. R., Valnickova-Hansen, Z., Scavenius, C., Benninger, R. K. P., Leahy, K. F., Johnson, R., Gally, F., Kosmider, B., Zimmermann, A. K., Enghild, J. J., Nozik-Grayck, E. & Bowler, R. P., Oct 1 2014, In : Circulation: Cardiovascular Genetics. 7, 5, p. 659-666 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
2015

The beneficial effects of exercise on cartilage are lost in mice with reduced levels of ECSOD in tissues

Pate, K. M., Sherk, V. D., Carpenter, R. D., Weaver, M., Crapo, S., Gally, F., Chatham, L. S., Goldstrohm, D. A., Crapo, J. D., Kohrt, W. M., Bowler, R. P., Oberley-Deegan, R. E. & Regan, E. A., Mar 15 2015, In : Journal of Applied Physiology. 118, 6, p. 760-767 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Curcumin enhances human macrophage control of Mycobacterium tuberculosis infection

Bai, X., Oberley-Deegan, R. E., Bai, A., Ovrutsky, A. R., Kinney, W. H., Weaver, M., Zhang, G., Honda, J. R. & Chan, E. D., Jul 1 2016, In : Respirology. 21, 5, p. 951-957 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

MnTE-2-PyP modulates thiol oxidation in a hydrogen peroxide-mediated manner in a human prostate cancer cell

Tong, Q., Zhu, Y., Galaske, J. W., Kosmacek, E. A., Chatterjee, A., Dickinson, B. C. & Oberley-Deegan, R. E., Dec 1 2016, In : Free Radical Biology and Medicine. 101, p. 32-43 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

MnTE-2-PyP reduces prostate cancer growth and metastasis by suppressing p300 activity and p300/HIF-1/CREB binding to the promoter region of the PAI-1 gene

Tong, Q., Weaver, M. R., Kosmacek, E. A., O'Connor, B. P., Harmacek, L., Venkataraman, S. & Oberley-Deegan, R. E., May 1 2016, In : Free Radical Biology and Medicine. 94, p. 185-194 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

MnTnBuOE-2-PyP protects normal colorectal fibroblasts from radiation damage and simultaneously enhances radio/chemotherapeutic killing of colorectal cancer cells

Kosmacek, E. A., Chatterjee, A., Tong, Q., Lin, C. & Oberley-Deegan, R. E., Jun 7 2016, In : Oncotarget. 7, 23, p. 34532-34545 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

Topically applied manganese-porphyrins BMX-001 and BMX-010 display a significant anti-inflammatory response in a mouse model of allergic dermatitis

Stover, K., Fukuyama, T., Young, A. T., Daniele, M. A., Oberley, R., Crapo, J. D. & Bäumer, W., Dec 1 2016, In : Archives of Dermatological Research. 308, 10, p. 711-721 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

Differential effects of superoxide dismutase mimetics after mechanical overload of articular cartilage

Coleman, M. C., Brouillette, M. J., Andresen, N. S., Oberley-Deegan, R. E. & Martin, J. M., Dec 2017, In : Antioxidants. 6, 4, 98.

Research output: Contribution to journalArticle

6 Scopus citations
19 Scopus citations

The SOD mimic, MNTE-2-pyp, protects from chronic fibrosis and inflammation in irradiated normal pelvic tissues

Shrishrimal, S., Kosmacek, E. A., Chatterjee, A., Tyson, M. J. & Oberley-Deegan, R. E., Dec 2017, In : Antioxidants. 6, 4, 87.

Research output: Contribution to journalArticle

13 Scopus citations
2018

p66Shc regulates migration of castration-resistant prostate cancer cells

Ingersoll, M. A., Chou, Y. W., Lin, J. S., Yuan, T. C., Miller, D. R., Xie, Y., Tu, Y., Oberley-Deegan, R. E., Batra, S. K. & Lin, M. F., Jun 2018, In : Cellular Signalling. 46, p. 1-14 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Superoxide dismutases (SODs) and SOD mimetics

Borgstahl, G. E. O. & Oberley-Deegan, R. E., Nov 2 2018, In : Antioxidants. 7, 11, 156.

Research output: Contribution to journalEditorial

4 Scopus citations

The addition of manganese porphyrins during radiation inhibits prostate cancer growth and simultaneously protects normal prostate tissue from radiation damage

Chatterjee, A., Zhu, Y., Tong, Q., Kosmacek, E. A., Lichter, E. Z. & Oberley-Deegan, R. E., Jan 2018, In : Antioxidants. 7, 1, 21.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations
2019

MnTE-2-PyP attenuates TGF-β-induced epithelial-mesenchymal transition of colorectal cancer cells by inhibiting the Smad2/3 signaling pathway

Yang, Y., Zhang, P., Yan, R., Wang, Q., Fang, E., Wu, H., Li, S., Tan, H., Zhou, X., Ma, X., Tang, Y., Huang, Y., Deng, R., Liu, Y., Tong, S., Wang, Z., Oberley-Deegan, R. E. & Tong, Q., 2019, In : Oxidative medicine and cellular longevity. 2019, 8639791.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

p66Shc protein through a redox mechanism enhances the progression of prostate cancer cells towards castration-resistance

Miller, D. R., Ingersoll, M. A., Chatterjee, A., Baker, B., Shrishrimal, S., Kosmacek, E. A., Zhu, Y., Cheng, P. W., Oberley-Deegan, R. E. & Lin, M. F., Aug 1 2019, In : Free Radical Biology and Medicine. 139, p. 24-34 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Reactive oxygen species drive epigenetic changes in radiation-induced fibrosis

Shrishrimal, S., Kosmacek, E. A. & Oberley-Deegan, R. E., 2019, In : Oxidative medicine and cellular longevity. 2019, 4278658.

Research output: Contribution to journalReview article

Open Access
18 Scopus citations

The ion channel, TRPM2, contributes to the pathogenesis of radiodermatitis

Perraud, A. L., Rao, D. M., Kosmacek, E. A., Dagunts, A., Oberley-Deegan, R. E. & Gally, F., Mar 8 2019, In : Radiation and Environmental Biophysics. 58, 1, p. 89-98 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2020

Adipocytes protect fibroblasts from radiation-induced damage by adiponectin secretion

Kosmacek, E. A. & Oberley-Deegan, R. E., Dec 1 2020, In : Scientific reports. 10, 1, 12616.

Research output: Contribution to journalArticle

Open Access

Assessing the effects of redox modifier MnTnBuOE-2-PyP 5+ on cognition and hippocampal physiology following doxorubicin, cyclophosphamide, and paclitaxel treatment

McElroy, T., Brown, T., Kiffer, F., Wang, J., Byrum, S. D., Oberley-Deegan, R. E. & Allen, A. R., Mar 1 2020, In : International journal of molecular sciences. 21, 5, 1867.

Research output: Contribution to journalArticle

Open Access

Manganese porphyrin, MnTE-2-PyP, treatment protects the prostate from radiation-induced fibrosis (RIF) by activating the NRF2 signaling pathway and enhancing SOD2 and sirtuin activity

Shrishrimal, S., Chatterjee, A., Kosmacek, E. A., Davis, P. J., McDonald, J. T. & Oberley-Deegan, R. E., May 20 2020, In : Free Radical Biology and Medicine. 152, p. 255-270 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses

Chatterjee, A., Kosmacek, E. A., Shrishrimal, S., McDonald, J. T. & Oberley-Deegan, R. E., Jul 2020, In : Redox Biology. 34, 101542.

Research output: Contribution to journalArticle

Open Access

Mnte-2-pyp suppresses prostate cancer cell growth via h2 o2 production

Zhu, Y., Kosmacek, E. A., Chatterjee, A. & Oberley-Deegan, R. E., Jun 2020, In : Antioxidants. 9, 6, 490.

Research output: Contribution to journalArticle

Open Access

MnTnBuOE-2-PyP treatment protects from radioactive iodine (I-131) treatment-related side effects in thyroid cancer

Patel, A., Kosmacek, E. A., Fisher, K. W., Goldner, W. & Oberley-Deegan, R. E., Mar 1 2020, In : Radiation and Environmental Biophysics. 59, 1, p. 99-109 11 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Nanoformulation of the superoxide dismutase mimic, MnTnBuOE-2-PyP5+, prevents its acute hypotensive response

Schlichte, S. L., Romanova, S., Katsurada, K., Kosmacek, E. A., Bronich, T. K., Patel, K. P., Oberley-Deegan, R. E. & Zimmerman, M. C., Sep 2020, In : Redox Biology. 36, 101610.

Research output: Contribution to journalArticle

Open Access

Sirt1–nox4 signaling axis regulates cancer cachexia

Dasgupta, A., Shukla, S. K., Vernucci, E., King, R. J., Abrego, J., Mulder, S. E., Mullen, N. J., Graves, G., Buettner, K., Thakur, R., Murthy, D., Attri, K. S., Wang, D., Chaika, N. V., Pacheco, C. G., Rai, I., Engle, D. D., Grandgenett, P. M., Punsoni, M., Reames, B. N. & 10 others, Teoh-Fitzgerald, M., Oberley-Deegan, R., Yu, F., Klute, K. A., Hollingsworth, M. A., Zimmerman, M. C., Mehla, K., Sadoshima, J., Tuveson, D. A. & Singh, P. K., Jul 6 2020, In : Journal of Experimental Medicine. 217, 7, e20190745.

Research output: Contribution to journalArticle

1 Scopus citations