Sameer Mirza, PhD

  • 913 Citations
  • 15 h-Index
20062020

Research output per year

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Research Output

  • 913 Citations
  • 15 h-Index
  • 33 Article
  • 2 Conference contribution
2020

Pan-Cancer Analysis Reveals the Diverse Landscape of Novel Sense and Antisense Fusion Transcripts

Vellichirammal, N. N., Albahrani, A., Banwait, J. K., Mishra, N. K., Li, Y., Roychoudhury, S., Kling, M. J., Mirza, S., Bhakat, K. K., Band, V., Joshi, S. S. & Guda, C., Mar 6 2020, In : Molecular Therapy - Nucleic Acids. 19, p. 1379-1398 20 p.

Research output: Contribution to journalArticle

Open Access
2019

Engineering hydrogel based cancer microenvironments for in vitro breast cancer cell culture and therapeutics screening

Shi, W., Kuss, M. A., Mohapatra, B., Mirza, S., Band, H., Band, V. & Duan, B., 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2018

3D Bioprinting of Breast Cancer Models for Drug Resistance Study

Wang, Y., Shi, W., Kuss, M., Mirza, S., Qi, D., Krasnoslobodtsev, A. V., Zeng, J., Band, H., Band, V. & Duan, B., Dec 10 2018, In : ACS Biomaterials Science and Engineering. 4, 12, p. 4401-4411 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

3D hydrogel breast cancer models for studying the effects of hypoxia on epithelial to mesenchymal transition

Wang, Y., Mirza, S., Wu, S., Zeng, J., Shi, W., Band, H., Band, V. & Duan, B., Aug 14 2018, In : Oncotarget. 9, 63, p. 32191-32203 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Loss of the nuclear pool of Ubiquitin ligase CHIP/STUB1 in breast cancer unleashes the MZF1-cathepsin pro-oncogenic program

Luan, H., Mohapatra, B., Bielecki, T. A., Mushtaq, I., Mirza, S., Jennings, T. A., Clubb, R. J., An, W., Ahmed, D., El-Ansari, R., Storck, M. D., Mishra, N. K., Guda, C., Sheinin, Y. M., Meza, J. L., Raja, S., Rakha, E. A., Band, V. & Band, H., May 15 2018, In : Cancer Research. 78, 10, p. 2524-2535 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Targeting PARP1 in XRCC1-deficient sporadic invasive breast cancer or preinvasive ductal carcinoma in situ induces synthetic lethality and chemoprevention

Ali, R., Al-Kawaz, A., Toss, M. S., Green, A. R., Miligy, I. M., Mesquita, K. A., Seedhouse, C., Mirza, S., Band, V., Rakha, E. A. & Madhusudan, S., Dec 15 2018, In : Cancer Research. 78, 24, p. 6818-6827 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway

Srivastava, S., Mohibi, S., Mirza, S., Band, H. & Band, V., Aug 18 2017, In : Cell Cycle. 16, 16, p. 1515-1525 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Mammalian ECD protein is a novel negative regulator of the PERK arm of the unfolded protein response

Olou, A. A., Sarkar, A., Bele, A., Gurumurthy, C. B., Mir, R. A., Ammons, S. A., Mirza, S., Saleem, I., Urano, F., Band, H. & Band, V., Sep 1 2017, In : Molecular and cellular biology. 37, 18, e00030-17.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Acetylation of mammalian ADA3 is required for its functional roles in histone acetylation and cell proliferation

Mohibi, S., Srivastava, S., Bele, A., Mirza, S., Band, H. & Band, V., 2016, In : Molecular and cellular biology. 36, 19, p. 2487-2502 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC

Griffin, N. I., Sharma, G., Zhao, X., Mirza, S., Srivastava, S., Dave, B. J., Aleskandarany, M., Rakha, E., Mohibi, S., Band, H. & Band, V., Nov 16 2016, In : Breast Cancer Research. 18, 1, 113.

Research output: Contribution to journalArticle

6 Scopus citations

A novel interaction of Ecdysoneless (ECD) protein with R2TP complex component RUVBL1 is required for the functional role of ECD in cell cycle progression

Mir, R. A., Bele, A., Mirza, S., Srivastava, S., Olou, A. A., Ammons, S. A., Kim, J. H., Gurumurthy, C. B., Qiu, F., Band, H. & Band, V., 2016, In : Molecular and cellular biology. 36, 6, p. 886-899 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Clinicopathological and prognostic significance of mitogen-activated protein kinases (MAPK) in breast cancers

Ahmad, D. A. J., Negm, O. H., Alabdullah, M. L., Mirza, S., Hamed, M. R., Band, V., Green, A. R., Ellis, I. O. & Rakha, E. A., Oct 1 2016, In : Breast Cancer Research and Treatment. 159, 3, p. 457-467 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Mutant PIK3CA induces EMT in a cell type specific manner

Bhagirath, D., Zhao, X., Mirza, S., West, W. W., Band, H. & Band, V., Dec 2016, In : PloS one. 11, 12, e0167064.

Research output: Contribution to journalArticle

1 Scopus citations
2015

Alteration/deficiency in activation 3 (ADA3) protein, a cell cycle regulator, associates with the centromere through CENP-B and regulates chromosome segregation

Mohibi, S., Srivastava, S., Wang-France, J., Mirza, S., Zhao, X., Band, H. & Band, V., Nov 20 2015, In : Journal of Biological Chemistry. 290, 47, p. 28299-28310 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

The cell cycle regulator ecdysoneless cooperates with H-ras to promote oncogenic transformation of human mammary epithelial cells

Bele, A., Mirza, S., Zhang, Y., Mir, R. A., Lin, S., Kim, J. H., Gurumurthy, C. B., West, W., Qiu, F., Band, H. & Band, V., Apr 1 2015, In : Cell Cycle. 14, 7, p. 990-1000 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways

Jerjees, D. A., Negm, O. H., Alabdullah, M. L., Mirza, S., Alkaabi, M., Hameed, M. R., Abduljabbar, R., Muftah, A., Nolan, C. C., Green, A. R., Tighe, P. J., Band, V., Ellis, I. O. & Rakha, E. A., 2015, In : Breast Cancer Research and Treatment. 150, 1, p. 91-103 13 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Cytoplasmic localization of alteration/deficiency in activation 3 (ADA3) predicts poor clinical outcome in breast cancer patients

Mirza, S., Rakha, E. A., Alshareeda, A., Mohibi, S., Zhao, X., Katafiasz, B. J., Wang, J., Gurumurthy, C. B., Bele, A., Ellis, I. O., Green, A. R., Band, H. & Band, V., Feb 2013, In : Breast Cancer Research and Treatment. 137, 3, p. 721-731 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Expression of DNA methyltransferases in breast cancer patients and to analyze the effect of natural compounds on DNA methyltransferases and associated proteins

Mirza, S., Sharma, G., Parshad, R., Gupta, S. D., Pandya, P. & Ralhan, R., Mar 2013, In : Journal of Breast Cancer. 16, 1, p. 23-31 9 p.

Research output: Contribution to journalArticle

Open Access
106 Scopus citations
2012

Alteration/deficiency in activation-3 (Ada3) plays a critical role in maintaining genomic stability

Mirza, S., Katafiasz, B. J., Kumar, R., Wang, J., Mohibi, S., Jain, S., Gurumurthy, C. B., Pandita, T. K., Dave, B. J., Band, H. & Band, V., Nov 15 2012, In : Cell Cycle. 11, 22, p. 4266-4274 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Clinical significance of promoter hypermethylation of ERβ and RARβ2 in tumor and serum DNA in Indian breast cancer patients

Mirza, S., Sharma, G., Parshad, R., Srivastava, A., Gupta, S. D. & Ralhan, R., Sep 2012, In : Annals of Surgical Oncology. 19, 9, p. 3107-3115 9 p.

Research output: Contribution to journalArticle

27 Scopus citations
31 Scopus citations

Mammalian alteration/deficiency in activation 3 (Ada3) is essential for embryonic development and cell cycle progression

Mohibi, S., Gurumurthy, C. B., Nag, A., Wang, J., Mirza, S., Mian, Y., Quinn, M., Katafiasz, B., Eudy, J. D., Pandey, S., Guda, C., Naramura, M., Band, H. & Band, V., Aug 24 2012, In : Journal of Biological Chemistry. 287, 35, p. 29442-29456 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Overexpression of a novel cell cycle regulator ecdysoneless in breast cancer: A marker of poor prognosis in HER2/neu-overexpressing breast cancer patients

Zhao, X., Mirza, S., Alshareeda, A., Zhang, Y., Gurumurthy, C. B., Bele, A., Kim, J. H., Mohibi, S., Goswami, M., Lele, S. M., West, W., Qiu, F., Ellis, I. O., Rakha, E. A., Green, A. R., Band, H. & Band, V., Jul 2012, In : Breast Cancer Research and Treatment. 134, 1, p. 171-180 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
2011

Breast cancer subtypes: Two decades of journey from cell culture to patients

Zhao, X., Gurumurthy, C. B., Malhotra, G., Mirza, S., Mohibi, S., Bele, A., Quinn, M. G., Band, H. & Band, V., 2011, Human Cell Transformation: Role of Stem Cells and the Microenvironment. Rhim, J. & Kremer, R. (eds.). p. 135-144 10 p. (Advances in Experimental Medicine and Biology; vol. 720).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Clinical significance of Maspin promoter methylation and loss of its protein expression in invasive ductal breast carcinoma: Correlation with VEGF-A and MTA1 expression

Sharma, G., Mirza, S., Parshad, R., Srivastava, A., Gupta, S. D., Pandya, P. & Ralhan, R., Feb 2011, In : Tumor Biology. 32, 1, p. 23-32 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Mouse models of estrogen receptor-positive breast cancer

Mohibi, S., Mirza, S., Band, H. & Band, V., 2011, In : Journal of Carcinogenesis. 10, 35.

Research output: Contribution to journalArticle

28 Scopus citations
2010

Clinical significance of promoter hypermethylation of DNA repair genes in tumor and serum DNA in invasive ductal breast carcinoma patients

Sharma, G., Mirza, S., Parshad, R., Srivastava, A., Gupta, S. D., Pandya, P. & Ralhan, R., Jul 2010, In : Life Sciences. 87, 3-4, p. 83-91 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Clinical significance of Stratifin, ERα and PR promoter methylation in tumor and serum DNA in Indian breast cancer patients

Mirza, S., Sharma, G., Parshad, R., Srivastava, A., Gupta, S. D. & Ralhan, R., Mar 2010, In : Clinical Biochemistry. 43, 4-5, p. 380-386 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

CpG hypomethylation of MDR1 gene in tumor and serum of invasive ductal breast carcinoma patients

Sharma, G., Mirza, S., Parshad, R., Srivastava, A., Datta Gupta, S., Pandya, P. & Ralhan, R., Mar 2010, In : Clinical Biochemistry. 43, 4-5, p. 373-379 7 p.

Research output: Contribution to journalArticle

52 Scopus citations

Demethylating agent 5-aza-2-deoxycytidine enhances susceptibility of breast cancer cells to anticancer agents

Mirza, S., Sharma, G., Pandya, P. & Ralhan, R., Sep 2010, In : Molecular and cellular biochemistry. 342, 1-2, p. 101-109 9 p.

Research output: Contribution to journalArticle

44 Scopus citations
2009

Prognostic relevance of promoter hypermethylation of multiple genes in breast cancer patients

Sharma, G., Mirza, S., Yang, Y. H., Parshad, R., Hazrah, P., Datta Gupta, S. & Ralhan, R., 2009, In : Cellular Oncology. 31, 6, p. 487-500 14 p.

Research output: Contribution to journalArticle

37 Scopus citations
2008

Epigenetic alterations of CDH1 and APC genes: Relationship with activation of Wnt/β-catenin Pathway in invasive ductal carcinoma of breast

Prasad, C. P., Mirza, S., Sharma, G., Prashad, R., DattaGupta, S., Rath, G. & Ralhan, R., Aug 29 2008, In : Life Sciences. 83, 9-10, p. 318-325 8 p.

Research output: Contribution to journalArticle

71 Scopus citations
2007

Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients

Sharma, G., Mirza, S., Prasad, C. P., Srivastava, A., Gupta, S. D. & Ralhan, R., Apr 24 2007, In : Life Sciences. 80, 20, p. 1873-1881 9 p.

Research output: Contribution to journalArticle

88 Scopus citations

Promoter hypermethylation of TMS1, BRCA1, ERα and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients

Mirza, S., Sharma, G., Prasad, C. P., Parshad, R., Srivastava, A., Gupta, S. D. & Ralhan, R., Jul 4 2007, In : Life Sciences. 81, 4, p. 280-287 8 p.

Research output: Contribution to journalArticle

90 Scopus citations
2006

Detection of RASSF1A and RARβ hypermethylation in serum DNA from breast cancer patients

Shukla, S., Mirza, S., Sharma, G., Parshad, R., Gupta, S. D. & Ralhan, R., 2006, In : Epigenetics. 1, 2, p. 88-93 6 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations