• 3585 Citations
  • 28 h-Index
1985 …2020

Research output per year

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Research Output

  • 3585 Citations
  • 28 h-Index
  • 127 Article
  • 5 Review article
  • 2 Conference contribution
  • 1 Chapter
2020

A Novel Combination Approach Targeting an Enhanced Protein Synthesis Pathway in MYC-driven (Group 3) Medulloblastoma

Chaturvedi, N. K., Kling, M. J., Griggs, C. N., Kesherwani, V., Shukla, M., McIntyre, E. M., Ray, S., Liu, Y., McGuire, T. R., Sharp, J. G., Band, H., Joshi, S. S. & Coulter, D. W., Jun 1 2020, In : Molecular cancer therapeutics. 19, 6, p. 1351-1362 12 p.

Research output: Contribution to journalArticle

Long non-coding RNA profiling of pediatric Medulloblastoma

Kesherwani, V., Shukla, M., Coulter, D. W., Sharp, J. G., Joshi, S. S., Chaturvedi, N. K. & Chaturvedi, N. K., Jun 26 2020, In : BMC Medical Genomics. 13, 1, 87.

Research output: Contribution to journalArticle

Open Access

Pan-Cancer Analysis Reveals the Diverse Landscape of Novel Sense and Antisense Fusion Transcripts

Vellichirammal, N. N., Albahrani, A., Banwait, J. K., Mishra, N. K., Li, Y., Roychoudhury, S., Kling, M. J., Mirza, S., Bhakat, K. K., Band, V., Joshi, S. S. & Guda, C., Mar 6 2020, In : Molecular Therapy - Nucleic Acids. 19, p. 1379-1398 20 p.

Research output: Contribution to journalArticle

Open Access
2019

A novel approach to eliminate therapy-resistant mantle cell lymphoma: synergistic effects of Vorinostat with Palbociclib

Chaturvedi, N. K., Hatch, N. D., Sutton, G. L., Kling, M., Vose, J. M. & Joshi, S. S., Apr 16 2019, In : Leukemia and Lymphoma. 60, 5, p. 1214-1223 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Role of protein arginine methyltransferase 5 in group 3 (MYC-driven) Medulloblastoma

Chaturvedi, N. K., Mahapatra, S., Kesherwani, V., Kling, M. J., Shukla, M., Ray, S., Kanchan, R., Perumal, N., McGuire, T. R., Graham Sharp, J., Joshi, S. S. & Coulter, D. W., Nov 6 2019, In : BMC cancer. 19, 1, 1056.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Targeting cyclin-dependent kinase 9 sensitizes medulloblastoma cells to chemotherapy

Song, H., Bhakat, R., Kling, M. J., Coulter, D. W., Chaturvedi, N. K., Ray, S. & Joshi, S. S., Dec 3 2019, In : Biochemical and Biophysical Research Communications. 520, 2, p. 250-256 7 p.

Research output: Contribution to journalArticle

Open Access
2018

Improved therapy for medulloblastoma: Targeting hedgehog and PI3K-mTOR signaling pathways in combination with chemotherapy

Chaturvedi, N. K., Kling, M. J., Coulter, D. W., McGuire, T. R., Ray, S., Kesherwani, V., Joshi, S. S. & Sharp, J. G., Mar 30 2018, In : Oncotarget. 9, 24, p. 16619-16633 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

Regulation of MAPK signaling and implications in chronic lymphocytic leukemia

Shukla, A., Shukla, V. & Joshi, S. S., Jul 3 2018, In : Leukemia and Lymphoma. 59, 7, p. 1565-1573 9 p.

Research output: Contribution to journalReview article

3 Scopus citations
4 Scopus citations
2017

The extracellular role of DNA damage repair protein APE1 in regulation of IL-6 expression

Nath, S., Roychoudhury, S., Kling, M. J., Song, H., Biswas, P., Shukla, A., Band, H., Joshi, S. & Bhakat, K. K., Nov 2017, In : Cellular Signalling. 39, p. 18-31 14 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Absence of caveolin-1 leads to delayed development of chronic lymphocytic leukemia in Eμ-TCL1 mouse model

Shukla, A., Cutucache, C. E., Sutton, G. L., Pitner, M. A., Rai, K., Rai, S., Opavsky, R., Swanson, P. C. & Joshi, S. S., Jan 1 2016, In : Experimental Hematology. 44, 1, p. 30-37.e1

Research output: Contribution to journalArticle

4 Scopus citations
20 Scopus citations

Improved therapy for neuroblastoma using a combination approach: Superior efficacy with vismodegib and topotecan

Chaturvedi, N. K., McGuire, T. R., Coulter, D. W., Shukla, A., McIntyre, E. M., Sharp, J. G. & Joshi, S. S., Mar 22 2016, In : Oncotarget. 7, 12, p. 15215-15229 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

Interferon regulatory factor 4 attenuates Notch signaling to suppress the development of chronic lymphocytic leukemia

Shukla, V., Shukla, A., Joshi, S. S. & Lu, R., May 25 2016, In : Oncotarget. 7, 27, p. 41081-41094 14 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Loss of Dnmt3a induces CLL and PTCL with distinct methylomes and transcriptomes in mice

Haney, S. L., Upchurch, G. M., Opavska, J., Klinkebiel, D., Appiah, A. K., Smith, L. M., Heavican, T. B., Iqbal, J., Joshi, S. & Opavsky, R., Sep 28 2016, In : Scientific reports. 6, 34222.

Research output: Contribution to journalArticle

6 Scopus citations

Modulation of p73 isoforms expression induces anti-proliferative and pro-apoptotic activity in mantle cell lymphoma independent of p53 status

Hassan, H. M., Varney, M. L., Chaturvedi, N. K., Joshi, S. S., Weisenburger, D. D., Singh, R. K. & Dave, B. J., Dec 1 2016, In : Leukemia and Lymphoma. 57, 12, p. 2874-2889 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a

Haney, S. L., Upchurch, G. M., Opavska, J., Klinkebiel, D., Hlady, R. A., Suresh, A., Pirruccello, S. J., Shukla, V., Lu, R., Costinean, S., Rizzino, A., Karpf, A. R., Joshi, S., Swanson, P. & Opavsky, R., May 10 2016, In : Cell Reports. 15, 6, p. 1190-1201 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Sprouty 2: A novel attenuator of B-cell receptor and MAPK-Erk signaling in CLL

Shukla, A., Rai, K., Shukla, V., Chaturvedi, N. K., Bociek, R. G., Pirruccello, S. J., Band, H., Lu, R. & Joshi, S. S., May 12 2016, In : Blood. 127, 19, p. 2310-2321 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Treatment of a chemoresistant neuroblastoma cell line with the antimalarial ozonide OZ513

Coulter, D. W., McGuire, T. R., Sharp, J. G., McIntyre, E. M., Dong, Y., Wang, X., Gray, S., Alexander, G. R., Chatuverdi, N. K., Joshi, S. S., Chen, X. & Vennerstrom, J. L., Nov 8 2016, In : BMC cancer. 16, 1, 867.

Research output: Contribution to journalArticle

2015
14 Scopus citations
2014

Chronic lymphocytic leukemia cells in a lymph node microenvironment depict molecular signature associated with an aggressive disease

Mittal, A. K., Chaturvedi, N. K., Rai, K. J., Cutucache, C. E., Nordgren, T. M., Moragues, M., Lu, R., Opavsky, R., Bociek, R. G., Weisenburger, D. D., Iqbal, J. & Joshi, S. S., 2014, In : Molecular Medicine. 20, 1, p. 290-301 12 p.

Research output: Contribution to journalArticle

39 Scopus citations
1 Scopus citations

Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing HB-EGF expression in macrophages

Kumar, S., Torres, M. P., Kaur, S., Rachagani, S., Joshi, S., Johansson, S. L., Momi, N., Baine, M. J., Gilling, C. E., Smith, L. M., Wyatt, T. A., Jain, M., Joshi, S. S. & Batra, S. K., Jun 9 2014, In : Oncogene. 34, 16, p. 2052-2060 9 p.

Research output: Contribution to journalArticle

25 Scopus citations
2013

Accelerated development of chronic lymphocytic leukemia in New Zealand black mice expressing a low level of interferon regulatory factor 4

Ma, S., Shukla, V., Fang, L., Gould, K. A., Joshi, S. S. & Lu, R., Sep 13 2013, In : Journal of Biological Chemistry. 288, 37, p. 26430-26440 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
8 Scopus citations

A role for IRF4 in the development of CLL

Shukla, V., Ma, S., Hardy, R. R., Joshi, S. S. & Lu, R., 2013, In : Blood. 122, 16, p. 2848-2855 8 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Novel treatment for mantle cell lymphoma including therapy-resistant tumor by NF-κB and mTOR dual-targeting approach

Chaturvedi, N. K., Rajule, R. N., Shukla, A., Radhakrishnan, P., Todd, G. L., Natarajan, A., Vose, J. M. & Joshi, S. S., Oct 2013, In : Molecular cancer therapeutics. 12, 10, p. 2006-2017 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Role of CTLA4 in the Proliferation and Survival of Chronic Lymphocytic Leukemia

Mittal, A. K., Chaturvedi, N. K., Rohlfsen, R. A., Gupta, P., Joshi, A. D., Hegde, G. V., Bociek, R. G. & Joshi, S. S., Aug 1 2013, In : PloS one. 8, 8, e70352.

Research output: Contribution to journalArticle

13 Scopus citations
2012

Establishment and characterization of therapy-resistant mantle cell lymphoma cell lines derived from diff erent tissue sites

Ahrens, A. K., Chaturvedi, N. K., Nordgren, T. M., Dave, B. J. & Joshi, S. S., Nov 2012, In : Leukemia and Lymphoma. 53, 11, p. 2269-2278 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis

Hlady, R. A., Novakova, S., Opavska, J., Klinkebiel, D., Peters, S. L., Bies, J., Hannah, J., Iqbal, J., Anderson, K. M., Siebler, H. M., Smith, L. M., Greiner, T. C., Bastola, D., Joshi, S., Lockridge, O., Simpson, M. A., Felsher, D. W., Wagner, K. U., Chan, W. C., Christman, J. K. & 1 others, Opavsky, R., Jan 3 2012, In : Journal of Clinical Investigation. 122, 1, p. 163-177 15 p.

Research output: Contribution to journalArticle

43 Scopus citations

Lymph node-induced immune tolerance in chronic lymphocytic leukaemia: A role for caveolin-1

Cutucache, C. E., Mittal, A. K., Chaturvedi, N. K., Iqbal, J., Aoun, P., Bierman, P. J., Bociek, R. G., Weisenburger, D. D. & Joshi, S. S., Jul 2012, In : British Journal of Haematology. 158, 2, p. 216-231 16 p.

Research output: Contribution to journalArticle

27 Scopus citations

Novel therapy for therapy-resistant mantle cell lymphoma: Multipronged approach with targeting of hedgehog signaling

Hegde, G. V., Nordgren, T. M., Munger, C. M., Mittal, A. K., Bierman, P. J., Weisenburger, D. D., Vose, J. M., Sharp, J. G. & Joshi, S. S., Dec 15 2012, In : International Journal of Cancer. 131, 12, p. 2951-2960 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Optimized adoptive T-cell therapy for the treatment of residual mantle cell lymphoma

Munger, C. M., Hegde, G. V., Weisenburger, D. D., Vose, J. M. & Joshi, S. S., Oct 2012, In : Cancer Immunology, Immunotherapy. 61, 10, p. 1819-1832 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Ritonavir exhibits limited efficacy as a single agent in treating aggressive mantle cell lymphoma

Nordgren, T. M., Hegde, G. V. & Joshi, S. S., 2012, In : Journal of Cancer Science and Therapy. 4, 4, p. 61-68 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2011

Antitumor efficacy, tumor distribution and blood pharmacokinetics of chitosan/glyceryl-monooleate nanostructures containing paclitaxel

Trickler, W. J., Munt, D. J., Jain, N., Joshi, S. S. & Dash, A. K., Apr 2011, In : Nanomedicine. 6, 3, p. 437-448 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

IRF4 is a suppressor of C-Myc induced B cell leukemia

Pathak, S., Ma, S., Trinh, L., Eudy, J., Wagner, K. U., Joshi, S. S. & Lu, R., 2011, In : PloS one. 6, 7, e22628.

Research output: Contribution to journalArticle

27 Scopus citations

Tumor-specific peptide-based vaccines containing the conformationally biased, response-selective C5a agonists EP54 and EP67 protect against aggressive large B cell lymphoma in a syngeneic murine model

Kollessery, G., Nordgren, T. M., Mittal, A. K., Joshi, S. S. & Sanderson, S. D., Aug 11 2011, In : Vaccine. 29, 35, p. 5904-5910 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2010

Ultrastructural basis of enhanced antitumor cytotoxicity of cord blood-derived CTLs: A comparative analysis with peripheral blood and bone marrow

Clark, E. M., Joshi, D. S., Grimm, A. B., Joshi, A. D., Wang, P. & Joshi, S. S., Sep 2010, In : International journal of oncology. 37, 3, p. 645-653 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2008
18 Scopus citations

Differential gene expression in murine large cell B-cell lymphoma metastatic variants

Joshi, S. S., Mittal, A. K., Wang, P., Joshi, A. D., Vu, E. & Wang, X., Sep 2008, In : International Immunopharmacology. 8, 9, p. 1257-1263 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: A potential new therapeutic target

Hegde, G. V., Peterson, K. J., Emanuel, K., Mittal, A. K., Joshi, A. D., Dickinson, J. D., Kollessery, G. J., Bociek, R. G., Bierman, P., Vose, J. M., Weisenburger, D. D. & Joshi, S. S., Dec 1 2008, In : Molecular Cancer Research. 6, 12, p. 1928-1936 9 p.

Research output: Contribution to journalArticle

86 Scopus citations

Targeting of sonic hedgehog-GLI signaling: A potential strategy to improve therapy for mantle cell lymphoma

Hegde, G. V., Munger, C. M., Emanuel, K., Joshi, A. D., Greiner, T. C., Weisenburger, D. D., Vose, J. M. & Joshi, S. S., 2008, In : Molecular cancer therapeutics. 7, 6, p. 1450-1460 11 p.

Research output: Contribution to journalArticle

64 Scopus citations
2007

ATM, CTLA4, MNDA, and HEM1 in high versus low CD38-expressing B-cell chronic lymphocytic leukemia

Joshi, A. D., Hegde, G. V., Dickinson, J. D., Mittal, A. K., Lynch, J. C., Eudy, J. D., Armitage, J. O., Bierman, P. J., Bociek, R. G., Devetten, M. P., Vose, J. M. & Joshi, S. S., Sep 15 2007, In : Clinical Cancer Research. 13, 18, p. 5295-5304 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
8 Scopus citations

Clinical implication of genome-wide profiling in diffuse large B-cell lymphoma and other subtypes of B-cell lymphoma

Iqbal, J., Joshi, S., Patel, K. N., Javed, S. I., Kucuk, C., Aabida, A., D'Amore, F. & Fu, K., Apr 1 2007, In : Indian Journal of Cancer. 44, 2, p. 72-86 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

Erythropoietin induces excessive neointima formation: A study in a rat carotid artery model of vascular injury

Reddy, M. K., Vasir, J. K., Hegde, G. V., Joshi, S. S. & Labhasetwar, V., Sep 2007, In : Journal of Cardiovascular Pharmacology and Therapeutics. 12, 3, p. 237-247 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Immunotherapy of human neuroblastoma using umbilical cord blood-derived effector cells

Joshi, A. D., Clark, E. M., Wang, P., Munger, C. M., Hegde, G. V., Sanderson, S., Dave, H. P. G. & Joshi, S. S., Jun 2007, In : Journal of Neuroimmune Pharmacology. 2, 2, p. 202-212 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Molecular basis of aggressive disease in chronic lymphocytic leukemia patients with 11q deletion and trisomy 12 chromosomal abnormalities

Mittal, A. K., Hegde, G. V., Aoun, P., Bociek, R. G., Dave, B. J., Joshi, A. D., Sanger, W. G., Weisenburger, D. D. & Joshi, S. S., Oct 2007, In : International journal of molecular medicine. 20, 4, p. 461-469 9 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations
2006
29 Scopus citations

Dendritic cell-based therapy for mantle cell lymphoma

Munger, C. M., Vose, J. M. & Joshi, S. S., Jun 2006, In : International journal of oncology. 28, 6, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations