Shilpa J Buch, PhD

Professor, Pharmacology & Experimental Neuroscience (PEN)
Director, Nebraska Center for Substance Abuse Research

Phone402-559-3465

Source: Scopus
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3 Active
4 Not started
15 Finished

The brain as a SIV reservoir under suppressive cART potentiation by drugs of abuse
Fox, H. S., Buch, S. J. & Byrareddy, S.
National Institutes of Health
9/15/16 → 8/31/21
Project: Research project
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs
Buch, S. J., Guo, M. & Hu, G.
National Institutes of Health
9/1/16 → 5/31/21
Project: Research project
The combinatorial effects of Opiates and the emerging promoter-variant strains of HIV-1 subtype C on HIV neuropathogensis and latency
Buch, S. J. & Byrareddy, S.
National Institutes of Health
8/15/16 → 7/31/21
Project: Research project
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome
Buch, S. J. & Guo, M.
Project: Research project
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine
Buch, S. J. & Guo, M.
Project: Research project

10569 Citations
44 h-Index
160 Article
23 Review article
9 Comment/debate
5 Chapter
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Chronic morphine administration differentially modulates viral reservoirs in a simian immunodeficiency virus SIVmac251-infected rhesus macaque model
Acharya, A., Olwenyi, O. A., Thurman, M., Pandey, K., Morsey, B. M., Lamberty, B., Ferguson, N., Callen, S., Fang, Q., Buch, S. J., Fox, H. S. & Byrareddy, S. N., Mar 2021, In: Journal of virology. 95, 5, e01657-20.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Corrigendum to “HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress” [Redox Biol. 40 (2021) 101843](S221323172031048X)(10.1016/j.redox.2020.101843)
Thangaraj, A., Chivero, E. T., Tripathi, A., Singh, S., Niu, F., Guo, M., Pillai, P., Periyasamy, P. & Buch, S., 2021, (Accepted/In press) In: Redox Biology. 101909.
Research output: Contribution to journal › Comment/debate › peer-review

Open Access
HIV-1 Productively Infects and Integrates in Bronchial Epithelial Cells
Devadoss, D., Singh, S. P., Acharya, A., Do, K. C., Periyasamy, P., Manevski, M., Mishra, N., Tellez, C. S., Ramakrishnan, S., Belinsky, S. A., Byrareddy, S. N., Buch, S., Chand, H. S. & Sopori, M., Feb 4 2021, In: Frontiers in Cellular and Infection Microbiology. 10, 612360.
Research output: Contribution to journal › Article › peer-review

Open Access
HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress
Thangaraj, A., Chivero, E. T., Tripathi, A., Singh, S., Niu, F., Guo, M. L., Pillai, P., Periyasamy, P. & Buch, S., Apr 2021, In: Redox Biology. 40, 101843.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
NLRP3 Inflammasome Blockade Reduces Cocaine-Induced Microglial Activation and Neuroinflammation
Chivero, E. T., Thangaraj, A., Tripathi, A., Periyasamy, P., Guo, M. L. & Buch, S., 2021, (Accepted/In press) In: Molecular Neurobiology.
Research output: Contribution to journal › Article › peer-review