Simon Sherman, PhD

  • 3090 Citations
  • 27 h-Index
1984 …2019

Research output per year

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Research Output

1H NMR-based determination of the three-dimensional structure of the human plasma fibronectin fragment containing inter-chain disulfide bonds

Kar, L., Lai, C. S., Wolff, C. E., Nettesheim, D., Sherman, S. & Johnson, M. E., 1993, In : Journal of Biological Chemistry. 268, 12, p. 8580-8589 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

A comparison of statistical approaches for genetic anticipation with application to pancreatic cancer

Havnatzki, G. R., Brand, R. E., Haynatzka, V. R., Lynch, H. T. & Sherman, S. A., 2007, Proceedings of the 40th Annual Hawaii International Conference on System Sciences 2007, HICSS'07. 4076630. (Proceedings of the Annual Hawaii International Conference on System Sciences).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

A generalized beta model for the age distribution of cancers: Application to pancreatic and kidney cancer

Mdzinarishvili, T., Gleason, M. X., Kinarsky, L. & Sherman, S., 2009, In : Cancer Informatics. 7, p. 183-197 15 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

A heuristic solution of the identifiability problem of the age-period-cohort analysis of cancer occurrence: Lung cancer example

Mdzinarishvili, T. & Sherman, S., Apr 4 2012, In : PloS one. 7, 4, e34362.

Research output: Contribution to journalArticle

5 Scopus citations

Alcohol and tobacco lower the age of presentation in sporadic pancreatic cancer in a dose-dependent manner: A multicenter study

Anderson, M. A., Zolotarevsky, E., Cooper, K. L., Sherman, S., Shats, O., Whitcomb, D. C., Lynch, H. T., Ghiorzo, P., Rubinstein, W. S., Vogel, K. J., Sasson, A. R., Grizzle, W. E., Ketcham, M. A., Lee, S. Y., Normolle, D., Plonka, C. M., Mertens, A. N., Tripon, R. C. & Brand, R. E., Nov 2012, In : American Journal of Gastroenterology. 107, 11, p. 1730-1739 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

A linear 23-residue peptide reveals a propensity to form an unusual native-like conformation

Sherman, S. A., Gmeiner, W. H., Kirnarskiy, L., Perini, F. & Ruddon, R. W., Dec 1995, In : Journal of Biomolecular Structure and Dynamics. 13, 3, p. 441-446 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Alteration of genomic responses to doxorubicin and prevention of MDR in breast cancer cells by a polymer excipient: Pluronic P85

Batrakova, E. V., Kelly, D. L., Li, S., Li, Y., Yang, Z., Xiao, L., Alakhova, D. Y., Sherman, S., Alakhov, V. Y. & Kabanov, A. V., Mar 2006, In : Molecular Pharmaceutics. 3, 2, p. 113-123 11 p.

Research output: Contribution to journalArticle

65 Scopus citations

Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

Nagaraj, S., Gupta, K., Pisarev, V., Kinarsky, L., Sherman, S., Kang, L., Herber, D. L., Schneck, J. & Gabrilovich, D. I., Jul 2007, In : Nature Medicine. 13, 7, p. 828-835 8 p.

Research output: Contribution to journalArticle

650 Scopus citations

A novel approach for analysis of the log-linear age-period-cohort model: Application to lung cancer incidence

Mdzinarishvili, T., Gleason, M. X. & Sherman, S., 2009, In : Cancer Informatics. 7, p. 271-280 10 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

A priori and a posteriori mixture distributions for using databases in protein structure determination

Sclove, S. L. & Sherman, S. A., Dec 8 1997, In : Journal of Molecular Structure: THEOCHEM. 419, 1-3, p. 245-255 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

A protein encoded by the bovine herpesvirus 1 open reading frame E gene induces neurite-like morphological changes in mouse neorublastoma cells and is expressed in trigeminal ganglionic neurons

Perez, S., Meyer, F., Henderson, G., Jiang, Y., Sherman, S., Doster, A., Inman, M. & Jones, C., Mar 2007, In : Journal of neurovirology. 13, 2, p. 139-149 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Basic equations and computing procedures for frailty modeling of carcinogenesis: Application to pancreatic cancer data

Mdzinarishvili, T. & Sherman, S., 2013, In : Cancer Informatics. 12, p. 67-81 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma

Iqbal, J., Sanger, W. G., Horsman, D. E., Rosenwald, A., Pickering, D. L., Dave, B., Dave, S., Xiao, L., Cao, K., Zhu, Q., Sherman, S., Hans, C. P., Weisenburger, D. D., Greiner, T. C., Gascoyne, R. D., Ott, G., Müller-Hermelink, H. K., Delabie, J., Braziel, R. M., Jaffe, E. S. & 8 others, Campo, E., Lynch, J. C., Connors, J. M., Vose, J. M., Armitage, J. O., Grogan, T. M., Staudt, L. M. & Chan, W. C., Jul 2004, In : American Journal of Pathology. 165, 1, p. 159-166 8 p.

Research output: Contribution to journalArticle

217 Scopus citations

Biologically active conformer of the effector region of human C5a and modulatory effects of N-terminal receptor binding determinants on activity

Finch, A. M., Vogen, S. M., Sherman, S. A., Kirnarsky, L., Taylor, S. M. & Sanderson, S. D., Mar 14 1997, In : Journal of Medicinal Chemistry. 40, 6, p. 877-884 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Breast Cancer Incidence in Black and White Women Stratified by Estrogen and Progesterone Receptor Statuses

Gleason, M. X., Mdzinarishvili, T. & Sherman, S., Nov 14 2012, In : PloS one. 7, 11, e49359.

Research output: Contribution to journalArticle

6 Scopus citations

Comment re: Cancer incidence falls for oldest

Mdzinarishvili, T., Gleason, M. X. & Sherman, S., Jan 1 2009, In : Cancer Research. 69, 1, p. 379 1 p.

Research output: Contribution to journalLetter

1 Scopus citations

Common genetic variants contribute to incomplete penetrance: evidence from cancer-free BRCA1 mutation carriers

Downs, B., Sherman, S., Cui, J., Kim, Y. C., Snyder, C., Christensen, M., Luo, J., Lynch, H. & Wang, S. M., Jan 2019, In : European Journal of Cancer. 107, p. 68-78 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
16 Scopus citations

Conformational studies on the MUC1 tandem repeat glycopeptides: Implication for the enzymatic O-glycosylation of the mucin protein core

Kinarsky, L., Suryanarayanan, G., Prakash, O., Paulsen, H., Clausen, H., Hanisch, F. G., Hollingsworth, M. A. & Sherman, S., Dec 2003, In : Glycobiology. 13, 12, p. 929-939 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

Decapeptide Agonists of Human C5a: The Relationship between Conformation and Neutrophil Response

Sanderson, S. D., Kimarsky, L., Sherman, S. A., Vogen, S. M., Prakash, O., Finch, A. M., Taylor, S. M. & Ember, J. A., Sep 1 1995, In : Journal of Medicinal Chemistry. 38, 18, p. 3669-3675 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Decapeptide Agonists of Human C5a: The Relationship between Conformation and Spasmogenic and Platelet Aggregatory Activities

Sanderson, S. D., Kimarsky, L., Sherman, S. A., Ember, J. A., Finch, A. M. & Taylor, S. M., Sep 1 1994, In : Journal of Medicinal Chemistry. 37, 19, p. 3171-3180 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Dendritic cell-based full-length survivin vaccine in treatment of experimental tumors

Nagaraj, S., Pisarev, V., Kinarsky, L., Sherman, S., Muro-Cacho, C., Altieri, D. C. & Gabrilovich, D. I., Feb 2007, In : Journal of Immunotherapy. 30, 2, p. 169-179 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Derivation of locally accurate spatial protein structure from NMR data

Sherman, S. A. & Johnson, M. E., 1993, In : Progress in Biophysics and Molecular Biology. 59, 3, p. 285-339 55 p.

Research output: Contribution to journalReview article

34 Scopus citations

Determination of glucagon conformation in lipid environment from data yielded by two-dimensional nuclear overhauser effect spectroscopy

Andrianov, A. M., Sherman, S. A. & Akhrem, A. A., 1990, In : Doklady Biophysics. 310-312, p. 13-16 4 p.

Research output: Contribution to journalArticle

Determination of structural elements related to the biological activities of a potent decapeptide agonist of human C5a anaphylatoxin

Vogen, S. M., Prakash, O., Kirnarsky, L., Sanderson, S. D. & Sherman, S. A., 1999, In : Journal of Peptide Research. 54, 1, p. 74-84 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Development of response-selective agonists of human C5a anaphylatoxin: Conformational, biological, and therapeutic considerations

Taylor, S. M., Sherman, S. A., Kirnarsky, L. & Sanderson, S. D., 2001, In : Current medicinal chemistry. 8, 6, p. 675-684 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Differential activities of decapeptide agonists of human C5a: The conformational effects of backbone N-methylation

Vogen, S. M., Paczkowski, N. J., Kirnarsky, L., Short, A., Whitmore, J. B., Sherman, S. A., Taylor, S. M. & Sanderson, S. D., 2001, In : International Immunopharmacology. 1, 12, p. 2151-2162 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Distinct gene expression profiles in different B-cell compartments in human peripheral lymphoid organs

Shen, Y., Iqbal, J., Xiao, L., Lynch, R. C., Rosenwald, A., Staudt, L. M., Sherman, S., Dybkaer, K., Zhou, G., Eudy, J. D., Delabie, J., McKeithan, T. W. & Chan, W. C., Sep 15 2004, In : BMC Immunology. 5, 20.

Research output: Contribution to journalArticle

41 Scopus citations

Dynamic properties of pH-dependent structural organization of the amyloidogenic β-protein (1-40)

Rubinstein, A., Lyubchenko, Y. L. & Sherman, S., Jan 2009, In : Prion. 3, 1, p. 31-43 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Effects of notch signaling on regulation of myeloid cell differentiation in cancer

Cheng, P., Kumar, V., Liu, H., Youn, J. I., Fishman, M., Sherman, S. & Gabrilovich, D., Jan 1 2014, In : Cancer Research. 74, 1, p. 141-152 12 p.

Research output: Contribution to journalArticle

46 Scopus citations
11 Scopus citations

Estimation of hazard functions in the log-linear age-period-cohort model: Application to lung cancer risk associated with geographical area

Mdzinarishvili, T., Gleason, M. X. & Sherman, S., 2010, In : Cancer Informatics. 9, p. 67-78 12 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
15 Scopus citations

Extension of Cox proportional hazard model for estimation of interrelated age-period-cohort effects on cancer survival

Mdzinarishvili, T., Gleason, M. X., Kinarsky, L. & Sherman, S., 2011, In : Cancer Informatics. 10, p. 31-44 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Family-specific, novel, deleterious germline variants provide a rich resource to identify genetic predispositions for BRCAx familial breast cancer

Wen, H., Kim, Y. C., Snyder, C., Xiao, F., Fleissner, E. A., Becirovic, D., Luo, J., Downs, B., Sherman, S., Cowan, K. H., Lynch, H. T. & Wang, S. M., Jun 26 2014, In : BMC cancer. 14, 1, 470.

Research output: Contribution to journalArticle

11 Scopus citations

Folding studies on the human chorionic gonadotropin β-subunit using optical spectroscopy of peptide fragments

Gangani, R. A., Silva, D., Sherman, S. A., Perini, F., Bedows, E. & Keiderling, T. A., Sep 13 2000, In : Journal of the American Chemical Society. 122, 36, p. 8623-8630 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Full-Length Dominant-Negative Survivin for Cancer Immunotherapy

Pisarev, V., Yu, B., Salup, R., Sherman, S., Altieri, D. C. & Gabrilovich, D. I., Dec 15 2003, In : Clinical Cancer Research. 9, 17, p. 6523-6533 11 p.

Research output: Contribution to journalArticle

94 Scopus citations

Functional Contributions of Noncysteine Residues within the Cystine Knots of Human Chorionic Gonadotropin Subunits

Darling, R. J., Wilken, J. A., Miller-Lindholm, A. K., Urlacher, T. M., Ruddon, R. W., Sherman, S. A. & Bedows, E., Apr 6 2001, In : Journal of Biological Chemistry. 276, 14, p. 10692-10699 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Grid-layout visualization method in the microarray data analysis interactive graphics toolkit

Xiao, L., Shats, O. & Sherman, S., 2003, Proceedings of the 36th Annual Hawaii International Conference on System Sciences, HICSS 2003. Sprague, R. H. (ed.). Institute of Electrical and Electronics Engineers Inc., 1174805. (Proceedings of the 36th Annual Hawaii International Conference on System Sciences, HICSS 2003).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Heuristic modeling of carcinogenesis for the population with dichotomous susceptibility to cancer: A pancreatic cancer example

Mdzinarishvili, T. & Sherman, S., Jun 16 2014, In : PloS one. 9, 6, e100087.

Research output: Contribution to journalArticle

3 Scopus citations

Identification of disulfide bonds among the nine core 2 N-acetylglucosaminyltransferase-M cysteines conserved in the mucin β6-N-acetylglucosaminyltransferase family

Singh, J., Khan, G. A., Kinarsky, L., Cheng, H., Wilken, J., Choi, K. H., Bedows, E., Sherman, S. & Cheng, P. W., Sep 10 2004, In : Journal of Biological Chemistry. 279, 37, p. 38969-38977 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of genes important in predicting the overall survival in patients with follicular lymphoma

Xiao, L., Fu, K., Iqbal, J., Chan, W. C. & Sherman, S., 2005, Proceedings of the 2005 International Conference on Data Mining, DMIN'05. p. 181-186 6 p. (Proceedings of the 2005 International Conference on Data Mining, DMIN'05).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Identification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes

Ninkovic, T., Kinarsky, L., Engelmann, K., Pisarev, V., Sherman, S., Finn, O. J. & Hanisch, F. G., Nov 2009, In : Molecular Immunology. 47, 1, p. 131-140 10 p.

Research output: Contribution to journalReview article

33 Scopus citations

Identification of subunit- and antagonist-specific amino acid residues in the N-methyl-D-aspartate receptor glutamate-binding pocket

Kinarsky, L., Feng, B., Skifter, D. A., Morley, R. M., Sherman, S., Jane, D. E. & Monaghan, D. T., Jun 2005, In : Journal of Pharmacology and Experimental Therapeutics. 313, 3, p. 1066-1074 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Improvement in accuracy of protein local structure determination from NMR data

Sherman, S., Sclove, S., Kirnarsky, L., Tomchin, I. & Shats, O., Sep 27 1996, In : Journal of Molecular Structure: THEOCHEM. 368, 1-3 SPEC. ISS., p. 153-161 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Improving the efficiency of protein structure determination from NMR

Kirnarsky, L., Shats, O. & Sherman, S., Dec 8 1997, In : Journal of Molecular Structure: THEOCHEM. 419, 1-3, p. 213-220 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Influence of the solvent structure on the interactions in proteins

Rubinstein, A. & Sherman, S., Sep 2004, In : Biophysical journal. 87, 3, p. 1544-1557 14 p.

Research output: Contribution to journalArticle

39 Scopus citations

Influence of time period and birth cohort effects on age-specific incidence rates of pancreatic and kidney cancer

Mdzinarishvili, T., Gleason, M. X. & Sherman, S., 2010, Proceedings of the 43rd Annual Hawaii International Conference on System Sciences, HICSS-43. 5428372. (Proceedings of the Annual Hawaii International Conference on System Sciences).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Introduction to advanced bioinformatics tools for translational research minitrack

Ali, H. H. & Sherman, S., 2008, Proceedings of the 41st Annual Hawaii International Conference on System Sciences 2008, HICSS. 4438931. (Proceedings of the Annual Hawaii International Conference on System Sciences).

Research output: Chapter in Book/Report/Conference proceedingConference contribution