Simon Sherman, PhD

  • 3058 Citations
  • 27 h-Index
1984 …2019

Research output per year

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Research Output

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Article
2019

Common genetic variants contribute to incomplete penetrance: evidence from cancer-free BRCA1 mutation carriers

Downs, B., Sherman, S., Cui, J., Kim, Y. C., Snyder, C., Christensen, M., Luo, J., Lynch, H. & Wang, S. M., Jan 2019, In : European Journal of Cancer. 107, p. 68-78 11 p.

Research output: Contribution to journalArticle

2016

Thyroid cancer and tumor collaborative registry (TCCR)

Shats, O., Goldner, W., Feng, J., Sherman, A., Smith, R. B. & Sherman, S., 2016, In : Cancer Informatics. 15, p. 73-79 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2015

Invariant characteristics of carcinogenesis

Sherman, S., Rathnayake, N. & Mdzinarishvili, T., Oct 14 2015, In : PloS one. 10, 10, e0140405.

Research output: Contribution to journalArticle

Two PALB2 germline mutations found in both BRCA1+ and BRCAx familial breast cancer

Downs, B., Kim, Y. C., Xiao, F., Snyder, C., Chen, P., Fleissner, E. A., Becirovic, D., Wen, H., Sherman, S., Cowan, K. H., Lynch, H. T. & Wang, S. M., May 1 2015, In : Breast Cancer Research and Treatment. 151, 1, p. 219-224 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Effects of notch signaling on regulation of myeloid cell differentiation in cancer

Cheng, P., Kumar, V., Liu, H., Youn, J. I., Fishman, M., Sherman, S. & Gabrilovich, D., Jan 1 2014, In : Cancer Research. 74, 1, p. 141-152 12 p.

Research output: Contribution to journalArticle

45 Scopus citations

Family-specific, novel, deleterious germline variants provide a rich resource to identify genetic predispositions for BRCAx familial breast cancer

Wen, H., Kim, Y. C., Snyder, C., Xiao, F., Fleissner, E. A., Becirovic, D., Luo, J., Downs, B., Sherman, S., Cowan, K. H., Lynch, H. T. & Wang, S. M., Jun 26 2014, In : BMC cancer. 14, 1, 470.

Research output: Contribution to journalArticle

11 Scopus citations

Heuristic modeling of carcinogenesis for the population with dichotomous susceptibility to cancer: A pancreatic cancer example

Mdzinarishvili, T. & Sherman, S., Jun 16 2014, In : PloS one. 9, 6, e100087.

Research output: Contribution to journalArticle

3 Scopus citations

Web tool for estimating the cancer hazard rates in aging

Mdzinarishvili, T., Sherman, A., Shats, O. & Sherman, S., Dec 17 2014, In : Cancer Informatics. 13, p. 197-205 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

Basic equations and computing procedures for frailty modeling of carcinogenesis: Application to pancreatic cancer data

Mdzinarishvili, T. & Sherman, S., 2013, In : Cancer Informatics. 12, p. 67-81 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Prognostic estimator of survival for patients with localized and extended pancreatic ductal adenocarcinoma

Gleason, M. X., Mdzinarishvili, T., Are, C., Sasson, A., Sherman, A., Shats, O. & Sherman, S., 2013, In : Cancer Informatics. 12, p. 103-114 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Prognostic Estimator of Survival for Patients with Localized and Extended Pancreatic Ductal Adenocarcinoma

Gleason, M. X., Mdzinarishvili, T., Are, C., Sasson, A., Sherman, A., Shats, O. & Sherman, S., Jan 1 2013, In : Cancer Informatics. 12

Research output: Contribution to journalArticle

Open Access
2012

A heuristic solution of the identifiability problem of the age-period-cohort analysis of cancer occurrence: Lung cancer example

Mdzinarishvili, T. & Sherman, S., Apr 4 2012, In : PloS one. 7, 4, e34362.

Research output: Contribution to journalArticle

5 Scopus citations

Alcohol and tobacco lower the age of presentation in sporadic pancreatic cancer in a dose-dependent manner: A multicenter study

Anderson, M. A., Zolotarevsky, E., Cooper, K. L., Sherman, S., Shats, O., Whitcomb, D. C., Lynch, H. T., Ghiorzo, P., Rubinstein, W. S., Vogel, K. J., Sasson, A. R., Grizzle, W. E., Ketcham, M. A., Lee, S. Y., Normolle, D., Plonka, C. M., Mertens, A. N., Tripon, R. C. & Brand, R. E., Nov 2012, In : American Journal of Gastroenterology. 107, 11, p. 1730-1739 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Breast Cancer Incidence in Black and White Women Stratified by Estrogen and Progesterone Receptor Statuses

Gleason, M. X., Mdzinarishvili, T. & Sherman, S., Nov 14 2012, In : PloS one. 7, 11, e49359.

Research output: Contribution to journalArticle

6 Scopus citations
2011

Extension of Cox proportional hazard model for estimation of interrelated age-period-cohort effects on cancer survival

Mdzinarishvili, T., Gleason, M. X., Kinarsky, L. & Sherman, S., 2011, In : Cancer Informatics. 10, p. 31-44 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Multicenter Breast Cancer Collaborative Registry

Sherman, S., Shats, O., Fleissner, E., Bascom, G., Yiee, K., Copur, M., Crow, K., Rooney, J., Mateen, Z., Ketcham, M. A., Feng, J., Sherman, A., Gleason, M., Kinarsky, L., Silva-Lopez, E., Edney, J., Reed, E., Berger, A. & Cowan, K., 2011, In : Cancer Informatics. 10, p. 217-226 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

PCCR: Pancreatic cancer collaborative registry

Sherman, S., Shats, O., Ketcham, M. A., Anderson, M. A., Whitcomb, D. C., Lynch, H. T., Ghiorzo, P., Rubinstein, W. S., Sasson, A. R., Grizzle, W. E., Haynatzki, G., Feng, J., Sherman, A., Kinarsky, L. & Brand, R. E., 2011, In : Cancer Informatics. 10, p. 83-91 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice

Lu, T., Ramakrishnan, R., Altiok, S., Youn, J. I., Cheng, P., Celis, E., Pisarev, V., Sherman, S., Sporn, M. B. & Gabrilovich, D., Oct 3 2011, In : Journal of Clinical Investigation. 121, 10, p. 4015-4029 15 p.

Research output: Contribution to journalArticle

189 Scopus citations
2010

Estimation of hazard functions in the log-linear age-period-cohort model: Application to lung cancer risk associated with geographical area

Mdzinarishvili, T., Gleason, M. X. & Sherman, S., 2010, In : Cancer Informatics. 9, p. 67-78 12 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Weibull-like model of cancer development in aging

Mdzinarishvili, T. & Sherman, S., 2010, In : Cancer Informatics. 9, p. 179-188 10 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2009

A generalized beta model for the age distribution of cancers: Application to pancreatic and kidney cancer

Mdzinarishvili, T., Gleason, M. X., Kinarsky, L. & Sherman, S., 2009, In : Cancer Informatics. 7, p. 183-197 15 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

A novel approach for analysis of the log-linear age-period-cohort model: Application to lung cancer incidence

Mdzinarishvili, T., Gleason, M. X. & Sherman, S., 2009, In : Cancer Informatics. 7, p. 271-280 10 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Dynamic properties of pH-dependent structural organization of the amyloidogenic β-protein (1-40)

Rubinstein, A., Lyubchenko, Y. L. & Sherman, S., Jan 2009, In : Prion. 3, 1, p. 31-43 13 p.

Research output: Contribution to journalArticle

11 Scopus citations
2008

Nitrated α-synuclein immunity accelerates degeneration of nigral dopaminergic neurons

Benner, E. J., Banerjee, R., Reynolds, A. D., Sherman, S., Pisarev, V. M., Tsiperson, V., Nemachek, C., Ciborowski, P., Przedborski, S., Mosley, R. L. & Gendelman, H. E., Jan 2 2008, In : PloS one. 3, 1, e1376.

Research output: Contribution to journalArticle

213 Scopus citations
2007

Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

Nagaraj, S., Gupta, K., Pisarev, V., Kinarsky, L., Sherman, S., Kang, L., Herber, D. L., Schneck, J. & Gabrilovich, D. I., Jul 2007, In : Nature Medicine. 13, 7, p. 828-835 8 p.

Research output: Contribution to journalArticle

637 Scopus citations

A protein encoded by the bovine herpesvirus 1 open reading frame E gene induces neurite-like morphological changes in mouse neorublastoma cells and is expressed in trigeminal ganglionic neurons

Perez, S., Meyer, F., Henderson, G., Jiang, Y., Sherman, S., Doster, A., Inman, M. & Jones, C., Mar 2007, In : Journal of neurovirology. 13, 2, p. 139-149 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dendritic cell-based full-length survivin vaccine in treatment of experimental tumors

Nagaraj, S., Pisarev, V., Kinarsky, L., Sherman, S., Muro-Cacho, C., Altieri, D. C. & Gabrilovich, D. I., Feb 2007, In : Journal of Immunotherapy. 30, 2, p. 169-179 11 p.

Research output: Contribution to journalArticle

43 Scopus citations
15 Scopus citations

Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells

Nefedova, Y., Fishman, M., Sherman, S., Wang, X., Beg, A. A. & Gabrilovich, D. I., Nov 15 2007, In : Cancer Research. 67, 22, p. 11021-11028 8 p.

Research output: Contribution to journalArticle

207 Scopus citations

New computational models for electrostatics of macromolecules in solvents

Dai, J., Tsukerman, I., Rubinstein, A. & Sherman, S., Apr 2007, In : IEEE Transactions on Magnetics. 43, 4, p. 1217-1220 4 p.

Research output: Contribution to journalArticle

12 Scopus citations
2006

Alteration of genomic responses to doxorubicin and prevention of MDR in breast cancer cells by a polymer excipient: Pluronic P85

Batrakova, E. V., Kelly, D. L., Li, S., Li, Y., Yang, Z., Xiao, L., Alakhova, D. Y., Sherman, S., Alakhov, V. Y. & Kabanov, A. V., Mar 2006, In : Molecular Pharmaceutics. 3, 2, p. 113-123 11 p.

Research output: Contribution to journalArticle

65 Scopus citations
2005

Identification of subunit- and antagonist-specific amino acid residues in the N-methyl-D-aspartate receptor glutamate-binding pocket

Kinarsky, L., Feng, B., Skifter, D. A., Morley, R. M., Sherman, S., Jane, D. E. & Monaghan, D. T., Jun 2005, In : Journal of Pharmacology and Experimental Therapeutics. 313, 3, p. 1066-1074 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Sequence-variant repeats of MUC1 show higher conformational flexibility, are less densely O-glycosylated and induce differential B lymphocyte responses

von Mensdorff-Pouilly, S., Kinarsky, L., Engelmann, K., Baldus, S. E., Verheijen, R. H., Hollingsworth, M. A., Pisarev, V., Sherman, S. & Hanisch, F. G., Aug 2005, In : Glycobiology. 15, 8, p. 735-746 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

T cells recognize PD(N/T)R motif common in a variable number of tandem repeat and degenerate repeat sequences of MUC1

Pisarev, V. M., Kinarsky, L., Caffrey, T., Hanisch, F. G., Sanderson, S., Hollingsworth, M. A. & Sherman, S., Feb 2005, In : International Immunopharmacology. 5, 2, p. 315-330 16 p.

Research output: Contribution to journalArticle

18 Scopus citations

The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membrane-tethered mucins

Palmai-Pallag, T., Khodabukus, N., Kinarsky, L., Leir, S. H., Sherman, S., Hollingsworth, M. A. & Harris, A., Jun 2005, In : FEBS Journal. 272, 11, p. 2901-2911 11 p.

Research output: Contribution to journalArticle

38 Scopus citations
2004

BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma

Iqbal, J., Sanger, W. G., Horsman, D. E., Rosenwald, A., Pickering, D. L., Dave, B., Dave, S., Xiao, L., Cao, K., Zhu, Q., Sherman, S., Hans, C. P., Weisenburger, D. D., Greiner, T. C., Gascoyne, R. D., Ott, G., Müller-Hermelink, H. K., Delabie, J., Braziel, R. M., Jaffe, E. S. & 8 others, Campo, E., Lynch, J. C., Connors, J. M., Vose, J. M., Armitage, J. O., Grogan, T. M., Staudt, L. M. & Chan, W. C., Jul 2004, In : American Journal of Pathology. 165, 1, p. 159-166 8 p.

Research output: Contribution to journalArticle

217 Scopus citations

Distinct gene expression profiles in different B-cell compartments in human peripheral lymphoid organs

Shen, Y., Iqbal, J., Xiao, L., Lynch, R. C., Rosenwald, A., Staudt, L. M., Sherman, S., Dybkaer, K., Zhou, G., Eudy, J. D., Delabie, J., McKeithan, T. W. & Chan, W. C., Sep 15 2004, In : BMC Immunology. 5, 20.

Research output: Contribution to journalArticle

40 Scopus citations

Identification of disulfide bonds among the nine core 2 N-acetylglucosaminyltransferase-M cysteines conserved in the mucin β6-N-acetylglucosaminyltransferase family

Singh, J., Khan, G. A., Kinarsky, L., Cheng, H., Wilken, J., Choi, K. H., Bedows, E., Sherman, S. & Cheng, P. W., Sep 10 2004, In : Journal of Biological Chemistry. 279, 37, p. 38969-38977 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Influence of the solvent structure on the interactions in proteins

Rubinstein, A. & Sherman, S., Sep 2004, In : Biophysical journal. 87, 3, p. 1544-1557 14 p.

Research output: Contribution to journalArticle

39 Scopus citations

Microarray analysis of differential gene expression in androgen independent prostate cancer using a metastatic human prostate cancer cell line model

Balaji, K. C., Rao, P. S., Smith, D. J., Louis, S., Smith, L. M., Sherman, S., Bacich, D. & O'Keefe, D., Jul 2004, In : Urologic Oncology: Seminars and Original Investigations. 22, 4, p. 313-320 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Molecular dynamics simulations of the O-glycosylated 21-residue MUC1 peptides

Rubinstein, A., Kinarsky, L. & Sherman, S., Mar 2004, In : International journal of molecular sciences. 5, 3, p. 119-128 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Molecular dynamics simulations of the O-glycosylated 21-residue MUC1 peptides

Rubinstein, A., Kinarsky, L. & Sherman, S., Mar 2004, In : International Journal of Molecular Sciences. 5, 3, p. 119-128 10 p.

Research output: Contribution to journalArticle

NMR-based structural studies of the glycosylated MUC1 tandem repeat peptide

Suryanarayanan, G., Keifer, P. A., Wang, G., Kinarsky, L., Hollingsworth, M. A. & Sherman, S., Mar 2004, In : International journal of molecular sciences. 5, 3, p. 84-92 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Suitability of Stratagene reference RNA for analysis of lymphoid tissues

Dybkær, K., Zhou, G., Iqbal, J., Kelly, D., Xiao, L., Sherman, S., D'Amore, F. & Chan, W. C., Sep 2004, In : BioTechniques. 37, 3, p. 470-474 5 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2003

Conformational studies on the MUC1 tandem repeat glycopeptides: Implication for the enzymatic O-glycosylation of the mucin protein core

Kinarsky, L., Suryanarayanan, G., Prakash, O., Paulsen, H., Clausen, H., Hanisch, F. G., Hollingsworth, M. A. & Sherman, S., Dec 2003, In : Glycobiology. 13, 12, p. 929-939 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

Full-Length Dominant-Negative Survivin for Cancer Immunotherapy

Pisarev, V., Yu, B., Salup, R., Sherman, S., Altieri, D. C. & Gabrilovich, D. I., Dec 15 2003, In : Clinical Cancer Research. 9, 17, p. 6523-6533 11 p.

Research output: Contribution to journalArticle

93 Scopus citations
2002

Role of disulphide bond formation in folding, secretion, and assembly of human chorionic gonadotropin subunits

Bedows, E., Darling, R. J., Wilken, J. A. & Sherman, S. A., 2002, In : Indian journal of experimental biology. 40, 4, p. 467-476 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2001

Development of response-selective agonists of human C5a anaphylatoxin: Conformational, biological, and therapeutic considerations

Taylor, S. M., Sherman, S. A., Kirnarsky, L. & Sanderson, S. D., 2001, In : Current medicinal chemistry. 8, 6, p. 675-684 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Differential activities of decapeptide agonists of human C5a: The conformational effects of backbone N-methylation

Vogen, S. M., Paczkowski, N. J., Kirnarsky, L., Short, A., Whitmore, J. B., Sherman, S. A., Taylor, S. M. & Sanderson, S. D., 2001, In : International Immunopharmacology. 1, 12, p. 2151-2162 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Functional Contributions of Noncysteine Residues within the Cystine Knots of Human Chorionic Gonadotropin Subunits

Darling, R. J., Wilken, J. A., Miller-Lindholm, A. K., Urlacher, T. M., Ruddon, R. W., Sherman, S. A. & Bedows, E., Apr 6 2001, In : Journal of Biological Chemistry. 276, 14, p. 10692-10699 8 p.

Research output: Contribution to journalArticle

9 Scopus citations