• 4008 Citations
  • 32 h-Index
1984 …2020

Research output per year

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Article
2020

Sorting nexin 17 (SNX17) links endosomal sorting to Eps15 homology domain protein 1 (EHD1)-mediated fission machinery

Dhawan, K., Naslavsky, N., Caplan, S. & Hanson, P. I., Mar 20 2020, In : Journal of Biological Chemistry. 295, 12, p. 3837-3850 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

MICAL-L1 coordinates ciliogenesis by recruiting EHD1 to the primary cilium

Xie, S., Farmer, T., Naslavsky, N. & Caplan, S., 2019, In : Journal of cell science. 132, 22, jcs233973.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Prostate tumor cell exosomes containing hyaluronidase Hyal1 stimulate prostate stromal cell motility by engagement of FAK-mediated integrin signaling

McAtee, C. O., Booth, C., Elowsky, C., Zhao, L., Payne, J., Fangman, T., Caplan, S., Henry, M. D. & Simpson, M. A., May 2019, In : Matrix Biology. 78-79, p. 165-179 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

Retromer facilitates the localization of Bcl-xL to the mitochondrial outer membrane

Farmer, T., O'Neill, K. L., Naslavsky, N., Luo, X. & Caplan, S., 2019, In : Molecular biology of the cell. 30, 10, p. 1138-1146 9 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2018

Novel CIL-102 derivatives as potential therapeutic agents for docetaxel-resistant prostate cancer

Miller, D. R., Tzeng, C. C., Farmer, T., Keller, E. T., Caplan, S., Chen, Y. S., Chen, Y. L. & Lin, M. F., Nov 1 2018, In : Cancer Letters. 436, p. 96-108 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Vesicular trafficking plays a role in centriole disengagement and duplication

Xie, S., Reinecke, J. B., Farmer, T., Bahl, K., Yeow, I., Nichols, B. J., McLamarrah, T. A., Naslavsky, N., Rogers, G. C. & Caplan, S., Nov 1 2018, In : Molecular biology of the cell. 29, 22, p. 2622-2631 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Control of mitochondrial homeostasis by endocytic regulatory proteins

Farmer, T., Reinecke, J. B., Xie, S., Bahl, K., Naslavsky, N. & Caplan, S., Jul 15 2017, In : Journal of cell science. 130, 14, p. 2359-2370 12 p.

Research output: Contribution to journalArticle

17 Scopus citations
2016
8 Scopus citations

The endocytic recycling compartment maintains cargo segregation acquired upon exit from the sorting endosome

Xie, S., Bahl, K., Reinecke, J. B., Hammond, G. R. V., Naslavsky, N. & Caplan, S., Jan 1 2016, In : Molecular biology of the cell. 27, 1, p. 108-126 19 p.

Research output: Contribution to journalArticle

25 Scopus citations
2015

Amyloid precursor-like protein 2 (APLP2) affects the actin cytoskeleton and increases pancreatic cancer growth and metastasis

Pandey, P., Rachagani, S., Das, S., Seshacharyulu, P., Sheinin, Y., Naslavsky, N., Pan, Z., Smith, B. L., Peters, H. L., Radhakrishnan, P., McKenna, N. R., Panapakkam Giridharan, S. S., Haridas, D., Kaur, S., Hollingsworth, M. A., MacDonald, R. G., Meza, J. L., Caplan, S., Batra, S. K. & Solheim, J. C., 2015, In : Oncotarget. 6, 4, p. 2064-2075 12 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation

Lu, Q., Insinna, C., Ott, C., Stauffer, J., Pintado, P. A., Rahajeng, J., Baxa, U., Walia, V., Cuenca, A., Hwang, Y. S., Daar, I. O., Lopes, S., Lippincott-Schwartz, J., Jackson, P. K., Caplan, S. & Westlake, C. J., Mar 2 2015, In : Nature Cell Biology. 17, 3, p. 228-240 13 p.

Research output: Contribution to journalArticle

99 Scopus citations

Hyaluronidase Hyal1 increases tumor cell proliferation and motility through accelerated vesicle trafficking

McAtee, C. O., Berkebile, A. R., Elowsky, C. G., Fangman, T., Barycki, J. J., Wahl, J. K., Khalimonchuk, O., Naslavsky, N., Caplan, S. & Simpson, M. A., May 22 2015, In : Journal of Biological Chemistry. 290, 21, p. 13144-13156 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Novel Functions for the Endocytic Regulatory Proteins MICAL-L1 and EHD1 in Mitosis

Reinecke, J. B., Katafiasz, D., Naslavsky, N. & Caplan, S., Jan 1 2015, In : Traffic. 16, 1, p. 48-67 20 p.

Research output: Contribution to journalArticle

16 Scopus citations

Role of the EHD2 unstructured loop in dimerization, protein binding and subcellular localization

Bahl, K., Naslavsky, N. & Caplan, S., Apr 15 2015, In : PloS one. 10, 4, e0123710.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Chemical shift assignments of the C-terminal Eps15 homology domain-3 EH domain

Spagnol, G., Reiling, C., Kieken, F., Caplan, S. & Sorgen, P. L., Oct 1 2014, In : Biomolecular NMR Assignments. 8, 2, p. 263-267 5 p.

Research output: Contribution to journalArticle

21 Scopus citations
Open Access
21 Scopus citations

Rapid degradation of the complement regulator, CD59, by a novel inhibitor

Cai, B., Xie, S., Liu, F., Simone, L. C., Caplan, S., Qin, X. & Naslavsky, N., Apr 25 2014, In : Journal of Biological Chemistry. 289, 17, p. 12109-12125 17 p.

Research output: Contribution to journalArticle

9 Scopus citations

Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1

Reinecke, J. B., Katafiasz, D., Naslavsky, N. & Caplan, S., 2014, In : Journal of cell science. 127, 8, p. 1684-1698 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

TC-PTP directly interacts with connexin43 to regulate gap junction intercellular communication

Li, H., Spagnol, G., Naslavsky, N., Caplan, S. & Sorgen, P. L., 2014, In : Journal of cell science. 127, 15, p. 3269-3279 11 p.

Research output: Contribution to journalArticle

19 Scopus citations
2013

Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis

Giridharan, S. S. P., Cai, B., Vitale, N., Naslavsky, N. & Caplan, S., Jun 1 2013, In : Molecular biology of the cell. 24, 11, p. 1776-1790 15 p.

Research output: Contribution to journalArticle

58 Scopus citations

Differential roles of C-terminal eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes

Cai, B., Giridharan, S. S. P., Zhang, J., Saxena, S., Bahl, K., Schmidt, J. A., Sorgen, P. L., Guo, W., Naslavsky, N. & Caplan, S., Oct 18 2013, In : Journal of Biological Chemistry. 288, 42, p. 30172-30180 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Role of Phosphatidylinositol 4,5-Bisphosphate in Regulating EHD2 Plasma Membrane Localization

Simone, L. C., Caplan, S. & Naslavsky, N., Sep 10 2013, In : PloS one. 8, 9, e74519.

Research output: Contribution to journalArticle

15 Scopus citations
2012
26 Scopus citations

Differential regulation of actin microfilaments by human MICAL proteins

Giridharan, S. S. P., Rohn, J. L., Naslavsky, N. & Caplan, S., Feb 1 2012, In : Journal of cell science. 125, 3, p. 614-624 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

MICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8a

Rahajeng, J., Panapakkam Giridharan, S. S., Cai, B., Naslavsky, N. & Caplan, S., Jan 2012, In : Traffic. 13, 1, p. 82-93 12 p.

Research output: Contribution to journalArticle

62 Scopus citations

Rabankyrin-5 Interacts with EHD1 and Vps26 to Regulate Endocytic Trafficking and Retromer Function

Zhang, J., Reiling, C., Reinecke, J. B., Prislan, I., Marky, L. A., Sorgen, P. L., Naslavsky, N. & Caplan, S., May 2012, In : Traffic. 13, 5, p. 745-757 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Retromer Guides STxB and CD8-M6PR from Early to Recycling Endosomes, EHD1 Guides STxB from Recycling Endosome to Golgi

Mckenzie, J. E., Raisley, B., Zhou, X., Naslavsky, N., Taguchi, T., Caplan, S. & Sheff, D., Aug 2012, In : Traffic. 13, 8, p. 1140-1159 20 p.

Research output: Contribution to journalArticle

41 Scopus citations

Trafficking cascades mediated by Rab35 and its membrane hub effector, MICAL-L1

Giridharan, S. S. P., Cai, B., Naslavsky, N. & Caplan, S., 2012, In : Communicative and Integrative Biology. 5, 4, p. 384-387 4 p.

Research output: Contribution to journalArticle

9 Scopus citations
2011

Regulation of major histocompatibility complex class i molecule expression on cancer cells by amyloid precursor-like protein 2

Peters, H. L., Tuli, A., Sharma, M., Naslavsky, N., Caplan, S., MacDonald, R. G. & Solheim, J. C., Oct 2011, In : Immunologic Research. 51, 1, p. 39-44 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2010

Alterations of EHD1/EHD4 protein levels interfere with L1/NgCAM endocytosis in neurons and disrupt axonal targeting

Yap, C. C. C., Lasiecka, Z. M., Caplan, S. & Winckler, B., May 12 2010, In : Journal of Neuroscience. 30, 19, p. 6646-6657 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Collapsin response mediator protein-2 (Crmp2) regulates trafficking by linking endocytic regulatory proteins to dynein motors

Rahajeng, J., Giridharan, S. S. P., Naslavsky, N. & Caplan, S., Oct 15 2010, In : Journal of Biological Chemistry. 285, 42, p. 31918-31922 5 p.

Research output: Contribution to journalArticle

41 Scopus citations
25 Scopus citations

E-cadherin differentially regulates the assembly of connexin43 and connexin32 into gap junctions in human squamous carcinoma cells

Chakraborty, S., Mitra, S., Falk, M. M., Caplan, S. H., Wheelock, M. J., Johnson, K. R. & Mehta, P. P., Apr 2 2010, In : Journal of Biological Chemistry. 285, 14, p. 10761-10776 16 p.

Research output: Contribution to journalArticle

32 Scopus citations

Mechanism for the selective interaction of C-terminal Eps15 Homology Domain Proteins With Specific Asn-Pro-Phe-containing partners

Kieken, F., Sharma, M., Jović, M., Giridharan, S. S. P., Naslavsky, N., Caplan, S. & Sorgen, P. L., Mar 19 2010, In : Journal of Biological Chemistry. 285, 12, p. 8687-8694 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Neuronal early endosomes require EHD1 for L1/NgCAM trafficking

Lasiecka, Z. M., Yap, C. C., Caplan, S. & Winckler, B., Dec 8 2010, In : Journal of Neuroscience. 30, 49, p. 16485-16497 13 p.

Research output: Contribution to journalArticle

29 Scopus citations
2009

A model for the role of EHD1-containing membrane tubules in endocytic recycling

Sharma, M., Jovic, M., Kieken, F., Naslavsky, N., Sorgen, P. & Caplan, S., 2009, In : Communicative and Integrative Biology. 2, 5, p. 431-433 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling

Pant, S., Sharma, M., Patel, K., Caplan, S., Carr, C. M. & Grant, B. D., Dec 2009, In : Nature Cell Biology. 11, 12, p. 1399-1410 12 p.

Research output: Contribution to journalArticle

125 Scopus citations

Amyloid precursor-like protein 2 association with HLA class i molecules

Tuli, A., Sharma, M., Wang, X., Simone, L. C., Capek, H. L., Cate, S., Hildebrand, W. H., Naslavsky, N., Caplan, S. & Solheim, J. C., Sep 2009, In : Cancer Immunology, Immunotherapy. 58, 9, p. 1419-1431 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

EHD3 regulates early-endosome-to-Golgi transport and preserves Golgi morphology

Naslavsky, N., McKenzie, J., Altan-Bonnet, N., Sheff, D. & Caplan, S., Feb 1 2009, In : Journal of cell science. 122, 3, p. 389-400 12 p.

Research output: Contribution to journalArticle

63 Scopus citations
54 Scopus citations

Mechanism for amyloid precursor-like protein 2 enhancement of major histocompatibility complex class I molecule degradation

Tuli, A., Sharma, M., Capek, H. L., Naslavsky, N., Caplan, S. & Solheim, J. C., Dec 4 2009, In : Journal of Biological Chemistry. 284, 49, p. 34296-34307 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

MHC molecules lead many lives. Workshop on MHC Class I Molecules at the interface between Biology & Medicine

Bowness, P., Caplan, S. & Edidin, M., 2009, In : EMBO Reports. 10, 1, p. 30-34 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling

Sharma, M., Giridharan, S. S. P., Rahajeng, J., Naslavsky, N. & Caplan, S., 2009, In : Molecular biology of the cell. 20, 24, p. 5181-5194 14 p.

Research output: Contribution to journalArticle

103 Scopus citations

Structural insight into the interaction of proteins containing NPF, DPF, and GPF motifs with the C-terminal EH-domain of EHD1

Kieken, F., Jović, M., Tonelli, M., Naslavsky, N., Caplan, S. & Sorgen, P. L., Dec 2009, In : Protein Science. 18, 12, p. 2471-2479 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2008

Amyloid precursor-like protein 2 increases the endocytosis, instability, and turnover of the H2-Kd MHC class I molecule

Tuli, A., Sharma, M., McIlhaney, M. M., Talmadge, J. E., Naslavsky, N., Caplan, S. & Solheim, J. C., Aug 1 2008, In : Journal of Immunology. 181, 3, p. 1978-1987 10 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

A role for EHD4 in the regulation of early endosomal transport

Sharma, M., Naslavsky, N. & Caplan, S., Jun 2008, In : Traffic. 9, 6, p. 995-1018 24 p.

Research output: Contribution to journalArticle

75 Scopus citations

Specificity of amyloid precursor-like protein 2 interactions with MHC class I molecules

Tuli, A., Sharma, M., Naslavsky, N., Caplan, S. & Solheim, J. C., Jun 2008, In : Immunogenetics. 60, 6, p. 303-313 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2007

EHD1 and Eps15 interact with phosphatidylinositols via their Eps15 homology domains

Naslavsky, N., Rahajeng, J., Chenavas, S., Sorgen, P. L. & Caplan, S., Jun 1 2007, In : Journal of Biological Chemistry. 282, 22, p. 16612-16622 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

EHD1 regulates cholesterol homeostasis and lipid droplet storage

Naslavsky, N., Rahajeng, J., Rapaport, D., Horowitz, M. & Caplan, S., Jun 8 2007, In : Biochemical and Biophysical Research Communications. 357, 3, p. 792-799 8 p.

Research output: Contribution to journalArticle

30 Scopus citations