Surinder Kumar Batra, PhD

  • 21495 Citations
  • 75 h-Index
1985 …2020

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Cigarette smoke-induced pancreatic damage - Experimental data

Wittel, U. A., Hopt, U. T. & Batra, S. K., Jul 2008, In : Langenbeck's Archives of Surgery. 393, 4, p. 581-588 8 p.

Research output: Contribution to journalArticle

37 Scopus citations

Cigarette Smoke Induces Stem Cell Features of Pancreatic Cancer Cells via PAF1

Nimmakayala, R. K., Seshacharyulu, P., Lakshmanan, I., Rachagani, S., Chugh, S., Karmakar, S., Rauth, S., Vengoji, R., Atri, P., Talmon, G. A., Lele, S. M., Smith, L. M., Thapa, I., Bastola, D., Ouellette, M. M., Batra, S. K. & Ponnusamy, M. P., Sep 2018, In : Gastroenterology. 155, 3, p. 892-908.e6

Research output: Contribution to journalArticle

20 Scopus citations

Cloning and sequencing of a human pancreatic tumor mucin cDNA

Lan, M. S., Batra, S. K., Qi, W. N., Metzgar, R. S. & Hollingsworth, M. A., 1990, In : Journal of Biological Chemistry. 265, 25, p. 15294-15299 6 p.

Research output: Contribution to journalArticle

353 Scopus citations

Codelivery of small molecule hedgehog inhibitor and miRNA for treating pancreatic cancer

Kumar, V., Mondal, G., Slavik, P., Rachagani, S., Batra, S. K. & Mahato, R. I., Apr 6 2015, In : Molecular Pharmaceutics. 12, 4, p. 1289-1298 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Combination of MUC1 and MUC4 expression predicts clinical outcome in patients with oral squamous cell carcinoma

Kamikawa, Y., Kanmura, Y., Hamada, T., Yamada, N., Macha, M. A., Batra, S. K., Higashi, M., Yonezawa, S. & Sugihara, K., Apr 1 2015, In : International Journal of Clinical Oncology. 20, 2, p. 298-307 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells

Matsuzaki, H., Schmied, B. M., Ulrich, A., Standop, J., Schneider, M. B., Batra, S. K., Picha, K. S. & Pour, P. M., Feb 2001, In : Clinical Cancer Research. 7, 2, p. 407-414 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

Combined targeting of epidermal growth factor receptor and hedgehog signaling by gefitinib and cyclopamine cooperatively improves the cytotoxic effects of docetaxel on metastatic prostate cancer cells

Mimeault, M., Johansson, S. L., Vankatraman, G., Moore, E., Henichart, J. P., Depreux, P., Lin, M. F. & Batra, S. K., Mar 2007, In : Molecular cancer therapeutics. 6, 3, p. 967-978 12 p.

Research output: Contribution to journalArticle

77 Scopus citations
Open Access
2 Scopus citations

Constructs of biotin mimetic peptide with CC49 single-chain Fv designed for tumor pretargeting

Pavlinkova, G., Batra, S. K., Colcher, D., Booth, B. J. M. & Baranowska-Kortylewicz, J., Mar 1 2003, In : Peptides. 24, 3, p. 353-362 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

CXCR2 signaling promotes secretory cancer-associated fibroblasts in pancreatic ductal adenocarcinoma

Awaji, M., Saxena, S., Wu, L., Prajapati, D. R., Purohit, A., Varney, M. L., Kumar, S., Rachagani, S., Ly, Q. P., Jain, M., Batra, S. K. & Singh, R. K., Jul 1 2020, In : FASEB Journal. 34, 7, p. 9405-9418 14 p.

Research output: Contribution to journalArticle

CXCR2 signaling regulates KRAS(G12D)-induced autocrine growth of pancreatic cancer

Purohit, A., Varney, M., Rachagani, S., Ouellette, M. M., Batra, S. K. & Singh, R. K., 2016, In : Oncotarget. 7, 6, p. 7280-7296 17 p.

Research output: Contribution to journalArticle

19 Scopus citations

Cytotoxic effects induced by a combination of cydopamine and gefitinib, the selective hedgehog and epidermal growth factor receptor signaling inhibitors, in prostate cancer cells

Mimeault, M., Moore, E., Moniaux, N., Hénichart, J. P., Depreux, P., Lin, M. F. & Batra, S. K., Feb 15 2006, In : International Journal of Cancer. 118, 4, p. 1022-1031 10 p.

Research output: Contribution to journalArticle

78 Scopus citations

Cytotoxic effects induced by docetaxel, gefitinib, and cyclopamine on side population and nonside population cell fractions from human invasive prostate cancer cells

Mimeault, M., Johansson, S. L., Henichart, J. P., Depreux, P. & Batra, S. K., Mar 2010, In : Molecular cancer therapeutics. 9, 3, p. 617-630 14 p.

Research output: Contribution to journalArticle

54 Scopus citations

Decreased androgen-responsive growth of human prostate cancer is associated with increased genetic alterations

Karan, D., Schmied, B. M., Dave, B. J., Wittel, U. A., Lin, M. F. & Batra, S. K., 2001, In : Clinical Cancer Research. 7, 11, p. 3472-3480 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Deregulation of MUC4 in gastric adenocarcinoma: Potential pathobiological implication in poorly differentiated non-signet ring cell type gastric cancer

Senapati, S., Chaturvedi, P., Sharma, P., Venkatraman, G., Meza, J. L., El-Rifai, W., Roy, H. K. & Batra, S. K., Sep 16 2008, In : British journal of cancer. 99, 6, p. 949-956 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Desmoplasia in pancreatic ductal adenocarcinoma: Insight into pathological function and therapeutic potential

Cannon, A., Thompson, C., Hall, B. R., Jain, M., Kumar, S. & Batra, S. K., Mar 2018, In : Genes and Cancer. 9, 3-4, p. 78-86 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Detection of the potential pancreatic cancer marker MUC4 in serum using surface-enhanced Raman scattering

Wang, G., Lipert, R. J., Jain, M., Kaur, S., Chakraboty, S., Torres, M. P., Batra, S. K., Brand, R. E. & Porter, M. D., Apr 1 2011, In : Analytical chemistry. 83, 7, p. 2554-2561 8 p.

Research output: Contribution to journalArticle

157 Scopus citations

Development and characterization of carboxy-terminus specific monoclonal antibodies for understanding MUC16 cleavage in human ovarian cancer

Aithal, A., Junker, W. M., Kshirsagar, P., Das, S., Kaur, S., Orzechowski, C., Gautam, S. K., Jahan, R., Sheinin, Y. M., Lakshmanan, I., Ponnusamy, M. P., Batra, S. K. & Jain, M., Apr 2018, In : PloS one. 13, 4, e0193907.

Research output: Contribution to journalArticle

5 Scopus citations

DF3 epitope expression on MUC1 mucin is associated with tumor aggressiveness, subsequent lymph node metastasis, and poor prognosis in patients with oral squamous cell carcinoma

Hamada, T., Nomura, M., Kamikawa, Y., Yamada, N., Batra, S. K., Yonezawa, S. & Sugihara, K., Nov 1 2012, In : Cancer. 118, 21, p. 5251-5264 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

Diagnosis of pancreatic neoplasms using a novel method of DNA methylation analysis of mucin expression in pancreatic juice

Yokoyama, S., Kitamoto, S., Higashi, M., Goto, Y., Hara, T., Ikebe, D., Yamaguchi, T., Arisaka, Y., Niihara, T., Nishimata, H., Tanaka, S., Takaori, K., Batra, S. K. & Yonezawa, S., Apr 8 2014, In : PloS one. 9, 4, e93760.

Research output: Contribution to journalArticle

18 Scopus citations

Diagnostic value of MUC4 immunostaining in distinguishing epithelial mesothelioma and lung adenocarcinoma

Llinares, K., Escande, F., Aubert, S., Buisine, M. P., De Bolos, C., Batra, S. K., Gosselin, B., Aubert, J. P., Porchet, N. & Copin, M. C., Feb 2004, In : Modern Pathology. 17, 2, p. 150-157 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

Differential gene expression analysis of peripheral blood mononuclear cells reveals novel test for early detection of pancreatic cancer

Baine, M. J., Menning, M., Smith, L. M., Mallya, K., Kaur, S., Rachagani, S., Chakraborty, S., Sasson, A. R., Brand, R. E. & Batra, S. K., 2011, In : Cancer Biomarkers. 11, 1, p. 1-14 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

Differential mutation spectrum and immune landscape in African Americans versus Whites: A possible determinant to health disparity in head and neck cancer

Chaudhary, S., Dam, V., Ganguly, K., Sharma, S., Atri, P., Chirravuri-Venkata, R., Cox, J. L., Sayed, Z., Jones, D. T., Ganti, A. K., Ghersi, D., Macha, M. A. & Batra, S. K., Nov 1 2020, In : Cancer Letters. 492, p. 44-53 10 p.

Research output: Contribution to journalArticle

Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL

Tan, Y. H. C., Mirzapoiazova, T., Won, B. M., Zhu, L., Srivastava, M. K., Vokes, E. E., Husain, A. N., Batra, S. K., Sharma, S. & Salgia, R., Dec 1 2017, In : Scientific reports. 7, 1, 9192.

Research output: Contribution to journalArticle

6 Scopus citations

Differentiating Peripherally-Located Small Cell Lung Cancer From Non-small Cell Lung Cancer Using a CT Radiomic Approach

Chen, B. T., Chen, Z., Ye, N., Mambetsariev, I., Fricke, J., Daniel, E., Wang, G., Wong, C. W., Rockne, R. C., Colen, R. R., Nasser, M. W., Batra, S. K., Holodny, A. I., Sampath, S. & Salgia, R., Apr 22 2020, In : Frontiers in Oncology. 10, 593.

Research output: Contribution to journalArticle

Open Access

Differentiation of islet cells in long-term culture

Schmied, B. M., Liu, G., Matsuzaki, H., Ulrich, A., Hernberg, S., Moyer, M. P., Weide, L., Murphy, L., Batra, S. K. & Pour, P. M., May 2000, In : Pancreas. 20, 4, p. 337-347 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Disruption of C1galt1 Gene Promotes Development and Metastasis of Pancreatic Adenocarcinomas in Mice

Chugh, S., Barkeer, S., Rachagani, S., Nimmakayala, R. K., Perumal, N., Pothuraju, R., Atri, P., Mahapatra, S., Thapa, I., Talmon, G. A., Smith, L. M., Yu, X., Neelamegham, S., Fu, J., Xia, L., Palanimuthu Ponnusamy, M. & Batra, S. K., Nov 2018, In : Gastroenterology. 155, 5, p. 1608-1624 17 p.

Research output: Contribution to journalArticle

13 Scopus citations

Divalent forms of CC49 single-chain antibody constructs in Pichia pastoris: Expression, purification, and characterization

Goel, A., Beresford, G. W., Colcher, D., Pavlinkova, G., Booth, B. J. M., Baranowska-Kortylewicz, J. & Batra, S. K., 2000, In : Journal of Biochemistry. 127, 5, p. 829-836 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

DNA methylation and histone H3-K9 modifications contribute to MUC17 expression

Kitamoto, S., Yamada, N., Yokoyama, S., Houjou, I., Higashi, M., Goto, M., Batra, S. K. & Yonezawa, S., Feb 2011, In : Glycobiology. 21, 2, p. 247-256 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer

Lin, W. C., Rajbhandari, N., Liu, C., Sakamoto, K., Zhang, Q., Triplett, A. A., Batra, S. K., Opavsky, R., Felsher, D. W., DiMaio, D. J., Hollingsworth, M. A., Morris IV, J. P., Hebrok, M., Witkiewicz, A. K., Brody, J. R., Rui, H. & Wagner, K. U., Mar 15 2013, In : Cancer Research. 73, 6, p. 1821-1830 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Dual delivery nanoscale device for miR-345 and gemcitabine co-delivery to treat pancreatic cancer

Uz, M., Kalaga, M., Pothuraju, R., Ju, J., Junker, W. M., Batra, S. K., Mallapragada, S. & Rachagani, S., Jan 28 2019, In : Journal of Controlled Release. 294, p. 237-246 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Dysregulated expression of MIC-1/PDF in human prostate tumor cells

Karan, D., Chen, S. J., Johansson, S. L., Singh, A. P., Paralkar, V. M., Lin, M. F. & Batra, S. K., Jun 6 2003, In : Biochemical and Biophysical Research Communications. 305, 3, p. 598-604 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

Early changes in islet hormone secretion in the hamster pancreatic cancer model

Goel, A. & Batra, S. K., 2001, In : Teratogenesis Carcinogenesis and Mutagenesis. 21, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Early diagnosis of pancreatic cancer: Neutrophil gelatinase-associated lipocalin as a marker of pancreatic intraepithelial neoplasia

Moniaux, N., Chakraborty, S., Yalniz, M., Gonzalez, J., Shostrom, V. K., Standop, J., Lele, S. M., Ouellette, M., Pour, P. M., Sasson, A. R., Brand, R. E., Hollingsworth, M. A., Jain, M. & Batra, S. K., May 6 2008, In : British journal of cancer. 98, 9, p. 1540-1547 8 p.

Research output: Contribution to journalArticle

121 Scopus citations

Easi-CRISPR: A robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins

Quadros, R. M., Miura, H., Harms, D. W., Akatsuka, H., Sato, T., Aida, T., Redder, R., Richardson, G. P., Inagaki, Y., Sakai, D., Buckley, S. M., Seshacharyulu, P., Batra, S. K., Behlke, M. A., Zeiner, S. A., Jacobi, A. M., Izu, Y., Thoreson, W. B., Urness, L. D., Mansour, S. L. & 2 others, Ohtsuka, M. & Gurumurthy, C. B., May 17 2017, In : Genome biology. 18, 1, 92.

Research output: Contribution to journalArticle

113 Scopus citations

Effects of humanization and gene shuffling on immunogenicity and antigen binding of anti-TAG-72 single-chain Fvs

Pavlinkova, G., Colcher, D., Booth, B. J. M., Goel, A., Wittel, U. A. & Batra, S. K., Dec 1 2001, In : International Journal of Cancer. 94, 5, p. 717-726 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Effects of selected deubiquitinating enzyme inhibitors on the proliferation and motility of lung cancer and mesothelioma cell lines

Mirzapoiazova, T., Pozhitkov, A., Nam, A., Mambetsariev, I., Nelson, M. S., Tan, Y. H. C., Zhang, K., Raz, D., Singhal, S., Nasser, M. W., Kulkarni, P., Batra, S. K., Sattler, M. & Salgia, R., Jul 2020, In : International journal of oncology. 57, 1, p. 80-86 7 p.

Research output: Contribution to journalArticle

Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: Implications for the development of novel cancer therapies

Torres, M. P., Ponnusamy, M. P., Chakraborty, S., Smith, L. M., Das, S., Arafat, H. A. & Batra, S. K., May 2010, In : Molecular cancer therapeutics. 9, 5, p. 1419-1431 13 p.

Research output: Contribution to journalArticle

74 Scopus citations

Elevated serum neutrophil gelatinase-associated lipocalin is an early predictor of severity and outcome in acute pancreatitis

Chakraborty, S., Kaur, S., Muddana, V., Sharma, N., Wittel, U. A., Papachristou, G. I., Whitcomb, D., Brand, R. E. & Batra, S. K., Sep 2010, In : American Journal of Gastroenterology. 105, 9, p. 2050-2059 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Emerging Roles of Electrospun Nanofibers in Cancer Research

Chen, S., Boda, S. K., Batra, S. K., Li, X. & Xie, J., Mar 21 2018, In : Advanced Healthcare Materials. 7, 6, 1701024.

Research output: Contribution to journalArticle

28 Scopus citations

Engineering and characterization of a divalent single-chain Fv angiotensin II fusion construct of the monoclonal antibody CC49

Wittel, U. A., Jain, M., Goel, A., Baranowska-Kortylewicz, J., Kurizaki, T., Chauhan, S. C., Agrawal, D. K., Colcher, D. & Batra, S. K., Apr 1 2005, In : Biochemical and Biophysical Research Communications. 329, 1, p. 168-176 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Epidermal growth factor down-regulates the expression of neutrophil gelatinase-associated lipocalin (NGAL) through E-cadherin in pancreatic cancer cells

Tong, Z., Chakraborty, S., Sung, B., Koolwal, P., Kaur, S., Aggarwal, B. B., Mani, S. A., Bresalier, R. S., Batra, S. K. & Guha, S., Jun 1 2011, In : Cancer. 117, 11, p. 2408-2418 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Epidermal growth factor ligand-independent, unregulated, cell- transforming potential of a naturally occurring human mutant EGFRvIII gene

Batra, S. K., Castelino-Prabhu, S., Wikstrand, C. J., Zhu, X., Humphrey, P. A., Friedman, H. S. & Bigner, D. D., 1995, In : Cell Growth and Differentiation. 6, 10, p. 1251-1259 9 p.

Research output: Contribution to journalArticle

234 Scopus citations

ErbB2 growth factor receptor, a marker for neuroendocrine cells?

Standop, J., Andrianifahanana, M., Moniaux, N., Schneider, M., Ulrich, A., Brand, R. E., Wisecarver, J. L., Bridge, J. A., Büchler, M. W., Adrian, T. E., Batra, S. K. & Pour, P. M., 2005, In : Pancreatology. 5, 1, p. 44-58 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

ErbB-2 signaling plays a critical role in regulating androgen-sensitive and castration-resistant androgen receptor-positive prostate cancer cells

Muniyan, S., Chen, S. J., Lin, F. F., Wang, Z., Mehta, P. P., Batra, S. K. & Lin, M. F., Nov 1 2015, In : Cellular Signalling. 27, 11, p. 2261-2271 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Establishment and characterization of androgen-independent human prostate cancer LNCaP cell model

Igawa, T., Lin, F. F., Lee, M. S., Karan, D., Batra, S. K. & Lin, M. F., 2002, In : Prostate. 50, 4, p. 222-235 14 p.

Research output: Contribution to journalArticle

157 Scopus citations

Establishment of human pancreatic ductal cells in a long-term culture

Ulrich, A. B., Schmied, B. M., Matsuzaki, H., El-Metwally, T., Moyer, M. P., Ricordi, C., Adrian, T. E., Batra, S. K. & Pour, P. M., 2000, In : Pancreas. 21, 4, p. 358-368 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas.

Karan, D., Lin, F. C., Bryan, M., Ringel, J., Moniaux, N., Lin, M. F. & Batra, S. K., Nov 2003, In : International journal of oncology. 23, 5, p. 1365-1371 7 p.

Research output: Contribution to journalArticle

70 Scopus citations

Expression of intestinal MUC17 membrane-bound mucin in inflammatory and neoplastic diseases of the colon

Senapati, S., Ho, S. B., Sharma, P., Das, S., Chakraborty, S., Kaur, S., Niehans, G. & Batra, S. K., Aug 2010, In : Journal of Clinical Pathology. 63, 8, p. 702-707 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Expression of MUC17 is regulated by HIF1α -mediated hypoxic responses and requires a methylation-free hypoxia responsible element in pancreatic cancer

Kitamoto, S., Yokoyama, S., Higashi, M., Yamada, N., Matsubara, S., Takao, S., Batra, S. K. & Yonezawa, S., Sep 10 2012, In : PloS one. 7, 9, e44108.

Research output: Contribution to journalArticle

13 Scopus citations