Surinder Kumar Batra, PhD

  • 21495 Citations
  • 75 h-Index
1985 …2020

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Expression of MUC4 mucin is observed mainly in the intestinal type of intraductal papillary mucinous neoplasm of the pancreas

Kitazono, I., Higashi, M., Kitamoto, S., Yokoyama, S., Horinouchi, M., Osako, M., Shimizu, T., Tabata, M., Batra, S. K., Goto, M. & Yonezawa, S., Oct 2013, In : Pancreas. 42, 7, p. 1120-1128 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Expression of mucin antigens (MUC1 and MUC16) as a prognostic factor for mucinous adenocarcinoma of the uterine cervix

Togami, S., Nomoto, M., Higashi, M., Goto, M., Yonezawa, S., Tsuji, T., Batra, S. K. & Douchi, T., Jun 2010, In : Journal of Obstetrics and Gynaecology Research. 36, 3, p. 588-597 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Expression of O6-Methylguanine-DNA Methyltransferase in Six Human Medulloblastoma Cell Lines

He, X., Ostrowski, L. E., Friedman, H. S., Wikstrand, C. J., Bigner, S. H., Rasheed, A., Batra, S. K. & Signer, D. D., Mar 1992, In : Cancer Research. 52, 5, p. 1144-1148 5 p.

Research output: Contribution to journalArticle

28 Scopus citations

Expression of TAG-72 in ovarian cancer and its correlation with tumor stage and patient prognosis

Ponnusamy, M. P., Venkatraman, G., Singh, A. P., Chauhan, S. C., Johansson, S. L., Jain, M., Smith, L., Davis, J. S., Remmenga, S. W. & Batra, S. K., Jun 28 2007, In : Cancer Letters. 251, 2, p. 247-257 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Expression of the human MUC1 mucin cDNA in a hamster pancreatic tumor cell line HP-1

Batra, S. K., Metzgar, R. S., Worlock, A. J. & Hollingsworth, M. A., Dec 1992, In : International Journal of Pancreatology. 12, 3, p. 271-283 13 p.

Research output: Contribution to journalArticle

10 Scopus citations
9 Scopus citations
Open Access
119 Scopus citations

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

Hoshino, A., Kim, H. S., Bojmar, L., Gyan, K. E., Cioffi, M., Hernandez, J., Zambirinis, C. P., Rodrigues, G., Molina, H., Heissel, S., Mark, M. T., Steiner, L., Benito-Martin, A., Lucotti, S., Di Giannatale, A., Offer, K., Nakajima, M., Williams, C., Nogués, L., Pelissier Vatter, F. A. & 97 others, Hashimoto, A., Davies, A. E., Freitas, D., Kenific, C. M., Ararso, Y., Buehring, W., Lauritzen, P., Ogitani, Y., Sugiura, K., Takahashi, N., Alečković, M., Bailey, K. A., Jolissant, J. S., Wang, H., Harris, A., Schaeffer, L. M., García-Santos, G., Posner, Z., Balachandran, V. P., Khakoo, Y., Raju, G. P., Scherz, A., Sagi, I., Scherz-Shouval, R., Yarden, Y., Oren, M., Malladi, M., Petriccione, M., De Braganca, K. C., Donzelli, M., Fischer, C., Vitolano, S., Wright, G. P., Ganshaw, L., Marrano, M., Ahmed, A., DeStefano, J., Danzer, E., Roehrl, M. H. A., Lacayo, N. J., Vincent, T. C., Weiser, M. R., Brady, M. S., Meyers, P. A., Wexler, L. H., Ambati, S. R., Chou, A. J., Slotkin, E. K., Modak, S., Roberts, S. S., Basu, E. M., Diolaiti, D., Krantz, B. A., Cardoso, F., Simpson, A. L., Berger, M., Rudin, C. M., Simeone, D. M., Jain, M., Ghajar, C. M., Batra, S. K., Stanger, B. Z., Bui, J., Brown, K. A., Rajasekhar, V. K., Healey, J. H., de Sousa, M., Kramer, K., Sheth, S., Baisch, J., Pascual, V., Heaton, T. E., La Quaglia, M. P., Pisapia, D. J., Schwartz, R., Zhang, H., Liu, Y., Shukla, A., Blavier, L., DeClerck, Y. A., LaBarge, M., Bissell, M. J., Caffrey, T. C., Grandgenett, P. M., Hollingsworth, M. A., Bromberg, J., Costa-Silva, B., Peinado, H., Kang, Y., Garcia, B. A., O'Reilly, E. M., Kelsen, D., Trippett, T. M., Jones, D. R., Matei, I. R., Jarnagin, W. R. & Lyden, D., Aug 20 2020, In : Cell. 182, 4, p. 1044-1061.e18

Research output: Contribution to journalArticle

FAK and paxillin, two potential targets in pancreatic cancer

Kanteti, R., Batra, S. K., Lennon, F. E. & Salgia, R., May 24 2016, In : Oncotarget. 7, 21, p. 31586-31601 16 p.

Research output: Contribution to journalArticle

41 Scopus citations

FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis

Seshacharyulu, P., Rachagani, S., Muniyan, S., Siddiqui, J. A., Cruz, E., Sharma, S., Krishnan, R., Killips, B. J., Sheinin, Y., Lele, S. M., Smith, L. M., Talmon, G. A., Ponnusamy, M. P., Datta, K. & Batra, S. K., Jun 27 2019, In : Oncogene. 38, 26, p. 5265-5280 16 p.

Research output: Contribution to journalArticle

5 Scopus citations

Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma

Kanteti, R., Mirzapoiazova, T., Riehm, J. J., Dhanasingh, I., Mambetsariev, B., Wang, J., Kulkarni, P., Kaushik, G., Seshacharyulu, P., Ponnusamy, M. P., Kindler, H. L., Nasser, M. W., Batra, S. K. & Salgia, R., Apr 3 2018, In : Cancer Biology and Therapy. 19, 4, p. 316-327 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types

Krop, I., Player, A., Tablante, A., Taylor-Parker, M., Lahti-Domenici, J., Fukuoka, J., Batra, S. K., Papadopoulos, N., Richards, W. G., Sugarbaker, D. J., Wright, R. L., Shim, J., Stamey, T. A., Sellers, W. R., Loda, M., Meyerson, M., Hruban, R., Jen, J. & Polyak, K., Sep 2004, In : Molecular Cancer Research. 2, 9, p. 489-494 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

Generation and characterization of a mouse/human chimeric antibody directed against extracellular matrix protein tenascin

He, X., Archer, G. E., Wikstrand, C. J., Morrison, S. L., Zalutsky, M. R., Bigner, D. D. & Batra, S. K., Jul 1994, In : Journal of Neuroimmunology. 52, 2, p. 127-137 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Generation and Characterization of Anti-MUC4 Monoclonal Antibodies Reactive with Normal and Cancer Cells in Humans

Moniaux, N., Varshney, G. C., Chauhan, S. C., Copin, M. C., Jain, M., Wittel, U. A., Andrianifahanana, M., Aubert, J. P. & Batra, S. K., Feb 2004, In : Journal of Histochemistry and Cytochemistry. 52, 2, p. 253-261 9 p.

Research output: Contribution to journalArticle

Open Access
68 Scopus citations

Genetically engineered tetravalent single-chain Fv of the pancarcinoma monoclonal antibody CC49: Improved biodistribution and potential for therapeutic application

Goel, A., Colcher, D., Baranowska-Kortylewiez, J., Augustine, S., Booth, B. J. M., Pavlinkova, G. & Batra, S. K., Dec 15 2000, In : Cancer Research. 60, 24, p. 6964-6971 8 p.

Research output: Contribution to journalArticle

103 Scopus citations

Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells

Singh, A. P., Bafna, S., Chaudhary, K., Venkatraman, G., Smith, L., Eudy, J. D., Johansson, S. L., Lin, M. F. & Batra, S. K., Jan 18 2008, In : Cancer Letters. 259, 1, p. 28-38 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

Genomic organization of MUC4 mucin gene: Towards the characterization of splice variants

Escande, F., Lemaitre, L., Moniaux, N., Batra, S. K., Aubert, J. P. & Buisine, M. P., 2002, In : European Journal of Biochemistry. 269, 15, p. 3637-3644 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Graviola: A novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism

Torres, M. P., Rachagani, S., Purohit, V., Pandey, P., Joshi, S., Moore, E. D., Johansson, S. L., Singh, P. K., Ganti, A. K. & Batra, S. K., Oct 1 2012, In : Cancer Letters. 323, 1, p. 29-40 12 p.

Research output: Contribution to journalArticle

86 Scopus citations

Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling

Macha, M. A., Rachagani, S., Gupta, S., Pai, P., Ponnusamy, M. P., Batra, S. K. & Jain, M., Dec 1 2013, In : Cancer Letters. 341, 2, p. 166-177 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

High gene expression of semaphorin 5A in pancreatic cancer is associated with tumor growth, invasion and metastasis

Sadanandam, A., Varney, M. L., Singh, S., Ashour, A. E., Moniaux, N., Deb, S., Lele, S. M., Batra, S. K. & Singh, R. K., Sep 1 2010, In : International Journal of Cancer. 127, 6, p. 1373-1383 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

Holy Basil leaf extract decreases tumorigenicity and metastasis of aggressive human pancreatic cancer cells in vitro and in vivo: Potential role in therapy

Shimizu, T., Torres, M. P., Chakraborty, S., Souchek, J. J., Rachagani, S., Kaur, S., Macha, M. A., Ganti, A. K., Hauke, R. J. & Batra, S. K., Aug 19 2013, In : Cancer Letters. 336, 2, p. 270-280 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

hPaf1/PD2 interacts with OCT3/4 to promote self-renewal of ovarian cancer stem cells

Karmakar, S., Seshacharyulu, P., Lakshmanan, I., Vaz, A. P., Chugh, S., Sheinin, Y. M., Mahapatra, S., Batra, S. K. & Palanimuthu Ponnusamy, M., 2017, In : Oncotarget. 8, 9, p. 14806-14820 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

Human intestinal MUC17 mucin augments intestinal cell restitution and enhances healing of experimental colitis

Luu, Y., Junker, W., Rachagani, S., Das, S., Batra, S. K., Heinrikson, R. L., Shekels, L. L. & Ho, S. B., Jun 2010, In : International Journal of Biochemistry and Cell Biology. 42, 6, p. 996-1006 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Human muc 1 mucin gene expression in the fetal pancreas

Batra, S. K., Metzgar, R. S. & Hollingsworth, M. A., May 1992, In : Pancreas. 7, 3, p. 391-393 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Human MUC4 mucin cDNA and its variants in pancreatic carcinoma

Choudhury, A., Moniaux, N., Winpenny, J. P., Hollingsworth, M. A., Aubert, J. P. & Batra, S. K., 2000, In : Journal of Biochemistry. 128, 2, p. 233-243 11 p.

Research output: Contribution to journalArticle

62 Scopus citations

Human MUC4 mucin induces ultra-structural changes and tumorigenicity in pancreatic cancer cells

Moniaux, N., Chaturvedi, P., Varshney, G. C., Meza, J. L., Rodriguez-Sierra, J. F., Aubert, J. P. & Batra, S. K., Jul 31 2007, In : British journal of cancer. 97, 3, p. 345-357 13 p.

Research output: Contribution to journalArticle

49 Scopus citations

Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth

Chuang, T. D., Chen, S. J., Lin, F. F., Veeramani, S., Kumar, S., Batra, S. K., Tu, Y. & Lin, M. F., Jul 30 2010, In : Journal of Biological Chemistry. 285, 31, p. 23598-23606 9 p.

Research output: Contribution to journalArticle

32 Scopus citations
18 Scopus citations
20 Scopus citations
192 Scopus citations

Identification and sequencing of the Syrian Golden hamster (Mesocricetus auratus) p16INK4a and p15INK4b cDNAs and their homozygous gene deletion in cheek pouch and pancreatic tumor cells

Muscarella, P., Knobloch, T. J., Ulrich, A. B., Casto, B. C., Moniaux, N., Wittel, U. A., Melvin, W. S., Pour, P. M., Song, H., Gold, B., Batra, S. K. & Weghorst, C. M., Oct 31 2001, In : Gene. 278, 1-2, p. 235-243 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

IFN-γ-induced expression of MUC4 in pancreatic cancer cells is mediated by STAT-1 upregulation: A novel mechanism for IFN-γ response

Andrianifahanana, M., Singh, A. P., Nemos, C., Ponnusamy, M. P., Moniaux, N., Mehta, P. P., Varshney, G. C. & Batra, S. K., Nov 8 2007, In : Oncogene. 26, 51, p. 7251-7261 11 p.

Research output: Contribution to journalArticle

39 Scopus citations

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology

Horn, A., Chakraborty, S., Dey, P., Haridas, D., Souchek, J., Batra, S. K. & Lele, S. M., Apr 2013, In : Archives of Pathology and Laboratory Medicine. 137, 4, p. 546-551 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Immunohistochemical expression of mucin antigens in gallbladder adenocarcinoma: MUC1-positive and MUC2-negative expression is associated with vessel invasion and shortened survival

Hiraki, T., Yamada, S., Higashi, M., Hatanaka, K., Yokoyama, S., Kitazono, I., Goto, Y., Kirishima, M., Batra, S. K., Yonezawa, S. & Tanimoto, A., Jun 2017, In : Histology and Histopathology. 32, 6, p. 585-596 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Immunohistochemical expression profiles of mucin antigens in salivary gland mucoepidermoid carcinoma: MUC4- and MUC6-negative expression predicts a shortened survival in the early postoperative phase

Honjo, K., Hiraki, T., Higashi, M., Noguchi, H., Nomoto, M., Yoshimura, T., Batra, S. K., Yonezawa, S., Semba, I., Nakamura, N., Tanimoto, A. & Yamada, S., Feb 2018, In : Histology and Histopathology. 33, 2, p. 201-213 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Immunohistochemical study of mucin expression in periampullary adenomyoma

Higashi, M., Goto, M., Saitou, M., Shimizu, T., Rousseau, K., Batra, S. K. & Yonezawa, S., May 2010, In : Journal of Hepato-Biliary-Pancreatic Sciences. 17, 3, p. 275-283 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Impaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway

Pandey, P., Seshacharyulu, P., Das, S., Rachagani, S., Ponnusamy, M. P., Yan, Y., Johansson, S. L., Datta, K., Lin, M. F. & Batra, S. K., Jun 25 2013, In : British journal of cancer. 108, 12, p. 2590-2600 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Improvement of cytotoxic effects induced by mitoxantrone on hormone-refractory metastatic prostate cancer cells by co-targeting epidermal growth factor receptor and hedgehog signaling cascades

Mimeault, M., Mehta, P. P., Hauke, R., Henichart, J. P., Depreux, P., Lin, M. F. & Batra, K. S., Dec 2007, In : Growth Factors. 25, 6, p. 400-416 17 p.

Research output: Contribution to journalArticle

19 Scopus citations

Incidence and prognostic significance of second primary cancers in renal cell carcinoma

Chakraborty, S., Tarantolo, S. R., Batra, S. K. & Hauke, R. J., Apr 2013, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 36, 2, p. 132-142 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Induction of adenocarcinoma from hamster pancreatic islet cells treated with N-nitrosobis(2-oxopropyl)amine in vitro

Schmied, B., Liu, G., Moyer, M. P., Hernberg, I. S. B., Sanger, W., Batra, S. & Pour, P. M., 1999, In : Carcinogenesis. 20, 2, p. 317-324 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells

Chipitsyna, G., Gong, Q., Anandanadesan, R., Alnajar, A., Batra, S. K., Wittel, U. A., Cullen, D. M., Akhter, M. P., Denhardt, D. T., Yeo, C. J. & Arafat, H. A., Jul 15 2009, In : International Journal of Cancer. 125, 2, p. 276-285 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Inhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma

Wang, J., Mirzapoiazova, T., Carol Tan, Y. H., Pang, K. M., Pozhitkov, A., Wang, Y., Wang, Y., Mambetsariev, B., Wang, E., Nasser, M. W., Batra, S. K., Raz, D., Reckamp, K., Kulkarni, P., Zheng, Y. & Salgia, R., Nov 2 2018, In : Cancer Biology and Therapy. 19, 11, p. 1023-1032 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Inhibition of hedgehog signaling improves the anti-carcinogenic effects of docetaxel in prostate cancer

Mimeault, M., Rachagani, S., Muniyan, S., Seshacharyulu, P., Johansson, S. L., Datta, K., Lin, M. F. & Batra, S. K., 2015, In : Oncotarget. 6, 6, p. 3887-3903 17 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Inhibition of MUC4 Expression Suppresses Pancreatic Tumor Cell Growth and Metastasis

Singh, A. P., Moniaux, N., Chauhan, S. C., Meza, J. L. & Batra, S. K., Jan 15 2004, In : Cancer Research. 64, 2, p. 622-630 9 p.

Research output: Contribution to journalArticle

191 Scopus citations

Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation

Yan, Y., Hein, A. L., Etekpo, A., Burchett, K. M., Lin, C., Enke, C. A., Batra, S. K., Cowan, K. H. & Ouellette, M. M., 2014, In : Oncotarget. 5, 21, p. 10251-10270 20 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells

Burchett, K. M., Etekpo, A., Batra, S. K., Yan, Y. & Ouellette, M. M., 2017, In : Oncotarget. 8, 48, p. 83754-83767 14 p.

Research output: Contribution to journalArticle

6 Scopus citations

Intracellular amyloid beta expression leads to dysregulation of the mitogen-activated protein kinase and bone morphogenetic protein-2 signaling axis

Cruz, E., Kumar, S., Yuan, L., Arikkath, J. & Batra, S. K., Feb 2018, In : PloS one. 13, 2, e0191696.

Research output: Contribution to journalArticle

5 Scopus citations

In Vitro Affinity Maturation of a Specificity-Determining Region-Grafted Humanized Anticarcinoma Antibody: Isolation and Characterization of Minimally Immunogenic High-Affinity Variants

De Pascalis, R., Gonzales, N. R., Padlan, E. A., Schuck, P., Batra, S. K., Schlom, J. & Kashmiri, S. V. S., Nov 15 2003, In : Clinical Cancer Research. 9, 15, p. 5521-5531 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: Comparison with its murine parent

Reist, C. J., Batra, S. K., Pegram, C. N., Bigner, D. D. & Zalutsky, M. R., Oct 1997, In : Nuclear Medicine and Biology. 24, 7, p. 639-647 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

In vitro induction of giant cell tumors from cultured hamster islets treated with N-nitrosobis(2-oxopropyl)amine

Matsuzaki, H., Schmied, B. M., Ulrich, A., Batra, S. K. & Pour, P. M., 2000, In : American Journal of Pathology. 156, 2, p. 439-443 5 p.

Research output: Contribution to journalArticle

3 Scopus citations