Surinder Kumar Batra, PhD

  • 21495 Citations
  • 75 h-Index
1985 …2020

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MUC4 Overexpression Augments Cell Migration and Metastasis through EGFR Family Proteins in Triple Negative Breast Cancer Cells

Mukhopadhyay, P., Lakshmanan, I., Ponnusamy, M. P., Chakraborty, S., Jain, M., Pai, P., Smith, L. M., Lele, S. M. & Batra, S. K., Feb 11 2013, In : PloS one. 8, 2, e54455.

Research output: Contribution to journalArticle

42 Scopus citations
52 Scopus citations

MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway

Macha, M. A., Rachagani, S., Pai, P., Gupta, S., Lydiatt, W. M., Smith, R. B., Johansson, S. L., Lele, S. M., Kakar, S. S., Lee, J. H., Meza, J., Ganti, A. K., Jain, M. & Batra, S. K., Mar 26 2015, In : Oncogene. 34, 13, p. 1698-1708 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cells

Ponnusamy, M. P., Seshacharyulu, P., Vaz, A., Dey, P. & Batra, S. K., 2011, In : Journal of Ovarian Research. 4, 1, 7.

Research output: Contribution to journalArticle

30 Scopus citations

MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling

Lakshmanan, I., Rachagani, S., Hauke, R., Krishn, S. R., Paknikar, S., Seshacharyulu, P., Karmakar, S., Nimmakayala, R. K., Kaushik, G., Johansson, S. L., Carey, G. B., Ponnusamy, M. P., Kaur, S., Batra, S. K. & Ganti, A. K., Aug 4 2016, In : Oncogene. 35, 31, p. 4112-4121 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: Potential implications for diagnosis and therapy

Rachagani, S., Torres, M. P., Kumar, S., Haridas, D., Baine, M., Macha, M. A., Kaur, S., Ponnusamy, M. P., Dey, P., Seshacharyulu, P., Johansson, S. L., Jain, M., Wagner, K. U. & Batra, S. K., 2012, In : Journal of Hematology and Oncology. 5, 68.

Research output: Contribution to journalArticle

40 Scopus citations

Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: A potential role of MUC4 as a tumormarker of diagnostic significance

Andrianifahanana, M., Moniaux, N., Ringel, J., Batra, S. K., Hollingsworth, M. A., Batra, S. K., Aubert, J. P., Schmied, B. M., Friess, H. & Büchler, M. W., 2001, In : Clinical Cancer Research. 7, 12, p. 4033-4040 8 p.

Research output: Contribution to journalArticle

210 Scopus citations

Mucin Expression in Endoscopic Ultrasound-Guided Fine-Needle Aspiration Specimens Is a Useful Prognostic Factor in Pancreatic Ductal Adenocarcinoma

Higashi, M., Yokoyama, S., Yamamoto, T., Goto, Y., Kitazono, I., Hiraki, T., Taguchi, H., Hashimoto, S., Fukukura, Y., Koriyama, C., Mataki, Y., Maemura, K., Shinchi, H., Jain, M., Batra, S. K. & Yonezawa, S., Jul 25 2015, In : Pancreas. 44, 5, p. 728-734 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Mucin expression in pleomorphic adenoma of salivary gland: A potential role of MUC1 as a marker to predict recurrence

Hamada, T., Matsukita, S., Goto, M., Kitajima, S., Batra, S. K., Irimura, T., Sueyoshi, K., Sugihara, K. & Yonezawa, S., Aug 2004, In : Journal of Clinical Pathology. 57, 8, p. 813-821 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer

Krishn, S. R., Kaur, S., Smith, L. M., Johansson, S. L., Jain, M., Patel, A., Gautam, S. K., Hollingsworth, M. A., Mandel, U., Clausen, H., Lo, W. C., Fan, W. T. L., Manne, U. & Batra, S. K., May 1 2016, In : Cancer Letters. 374, 2, p. 304-314 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: Clinical implication for improved colon surveillance

Krishn, S. R., Kaur, S., Sheinin, Y. M., Smith, L. M., Gautam, S. K., Patel, A., Jain, M., Juvvigunta, V., Pai, P., Lazenby, A. J., Roy, H. K. & Batra, S. K., 2017, In : Oncotarget. 8, 4, p. 7025-7038 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Nano-immunoassay with improved performance for detection of cancer biomarkers

Krasnoslobodtsev, A. V., Torres, M. P., Kaur, S., Vlassiouk, I. V., Lipert, R. J., Jain, M., Batra, S. K. & Lyubchenko, Y. L., Jan 1 2015, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 11, 1, p. 167-173 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
14 Scopus citations

Neural invasion in the staging of pancreatic cancer

Pour, P. M., Bell, R. H. & Batra, S. K., May 2003, In : Pancreas. 26, 4, p. 322-325 4 p.

Research output: Contribution to journalArticle

83 Scopus citations

Neuropilin-2 regulates endosome maturation and EGFR trafficking to support cancer cell pathobiology

Dutta, S., Roy, S., Polavaram, N. S., Stanton, M. J., Zhang, H., Bhola, T., Hönscheid, P., Donohue, T. M., Band, H., Batra, S. K., Muders, M. H. & Datta, K., Jan 15 2016, In : Cancer Research. 76, 2, p. 418-428 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Neutrophil gelatinase-associated lipocalin, macrophage inhibitory cytokine 1, and carbohydrate antigen 19-9 in pancreatic juice: Pathobiologic implications in diagnosing benign and malignant disease of the pancreas

Kaur, S., Baine, M. J., Guha, S., Ochi, N., Chakraborty, S., Mallya, K., Thomas, C., Crook, J., Wallace, M. B., Woodward, T. A., Jain, M., Singh, S., Sasson, A. R., Skinner, V., Raimondo, M. & Batra, S. K., Apr 2013, In : Pancreas. 42, 3, p. 494-501 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
21 Scopus citations

Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through α7nAChR-mediated MUC4 upregulation

Momi, N., Ponnusamy, M. P., Kaur, S., Rachagani, S., Kunigal, S. S., Chellappan, S., Ouellette, M. M. & Batra, S. K., Mar 14 2013, In : Oncogene. 32, 11, p. 1384-1395 12 p.

Research output: Contribution to journalArticle

78 Scopus citations

Novel combination therapy against metastatic and androgen-independent prostate cancer by using gefitinib, tamoxifen and etoposide

Mimeault, M., Venkatraman, G., Johansson, S. L., Moore, E., Henichart, J. P., Depreux, P., Lin, M. F. & Batra, S. K., Jan 1 2007, In : International Journal of Cancer. 120, 1, p. 160-169 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Novel HER3/MUC4 oncogenic signaling aggravates the tumorigenic phenotypes of pancreatic cancer cells

Lakshmanan, I., Seshacharyulu, P., Haridas, D., Rachagani, S., Gupta, S., Joshi, S., Guda, C., Yan, Y., Jain, M., Ganti, A. K., Ponnusamy, M. P. & Batra, S. K., 2015, In : Oncotarget. 6, 25, p. 21085-21099 15 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Novel imidazopyridine derivatives possess anti-tumor effect on human castration-resistant prostate cancer cells

Ingersoll, M. A., Lyons, A. S., Muniyan, S., D'Cunha, N., Robinson, T., Hoelting, K., Dwyer, J. G., Bu, X. R., Batra, S. K. & Lin, M. F., Jun 29 2015, In : PloS one. 10, 6, e0131811.

Research output: Contribution to journalArticle

9 Scopus citations

Novel interaction of MUC4 and galectin: Potential pathobiological implications for metastasis in lethal pancreatic cancer

Senapati, S., Chaturvedi, P., Chaney, W. G., Chakraborty, S., Gnanapragassam, V. S., Sasson, A. R. & Batra, S. K., Jan 15 2011, In : Clinical Cancer Research. 17, 2, p. 267-274 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Novel pancreatic cancer cell lines derived from genetically engineered mouse models of spontaneous pancreatic adenocarcinoma: Applications in diagnosis and therapy

Torres, M. P., Rachagani, S., Souchek, J. J., Mallya, K., Johansson, S. L. & Batra, S. K., Nov 20 2013, In : PloS one. 8, 11, e80580.

Research output: Contribution to journalArticle

51 Scopus citations

Novel role of O-glycosyltransferases GALNT3 and B3GNT3 in the self-renewal of pancreatic cancer stem cells

Barkeer, S., Chugh, S., Karmakar, S., Kaushik, G., Rauth, S., Rachagani, S., Batra, S. K. & Ponnusamy, M. P., Nov 22 2018, In : BMC cancer. 18, 1, 1157.

Research output: Contribution to journalArticle

8 Scopus citations
21 Scopus citations

NRP2 transcriptionally regulates its downstream effector WDFY1

Dutta, S., Roy, S., Polavaram, N. S., Baretton, G. B., Muders, M. H., Batra, S. & Datta, K., Mar 30 2016, In : Scientific reports. 6, 23588.

Research output: Contribution to journalArticle

9 Scopus citations

Ovarian Cancer Stem Cells: Unraveling a Germline Connection

Parte, S. C., Smolenkov, A., Batra, S. K., Ratajczak, M. Z. & Kakar, S. S., Dec 15 2017, In : Stem Cells and Development. 26, 24, p. 1781-1803 23 p.

Research output: Contribution to journalArticle

7 Scopus citations

Overexpression of ecdysoneless in pancreatic cancer and its role in oncogenesis by regulating glycolysis

Dey, P., Rachagani, S., Chakraborty, S., Singh, P. K., Zhao, X., Gurumurthy, C. B., Anderson, J. M., Lele, S., Hollingsworth, M. A., Band, V. & Batra, S. K., Nov 15 2012, In : Clinical Cancer Research. 18, 22, p. 6188-6198 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway

Senapati, S., Rachagani, S., Chaudhary, K., Johansson, S. L., Singh, R. K. & Batra, S. K., Mar 2010, In : Oncogene. 29, 9, p. 1293-1302 10 p.

Research output: Contribution to journalArticle

85 Scopus citations

Overexpression of PD2 leads to increased tumorigenicity and metastasis in pancreatic ductal adenocarcinoma

Vaz, A. P., Deb, S., Rachagani, S., Dey, P., Muniyan, S., Lakshmanan, I., Karmakar, S., Smith, L., Johansson, S., Lele, S., Ouellette, M., Ponnusamy, M. P. & Batra, S. K., 2016, In : Oncotarget. 7, 3, p. 3317-3331 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

Oxidant stress increases heat shock protein 70 mRNA in isolated perfused rat heart

Kukreja, R. C., Kontos, M. C., Loesser, K. E., Batra, S. K., Qian, Y. Z., Gbur, C. J., Naseem, S. A., Jesse, R. L. & Hess, M. L., 1994, In : American Journal of Physiology - Heart and Circulatory Physiology. 267, 6 36-6, p. H2213-H2219

Research output: Contribution to journalArticle

128 Scopus citations

p66Shc regulates migration of castration-resistant prostate cancer cells

Ingersoll, M. A., Chou, Y. W., Lin, J. S., Yuan, T. C., Miller, D. R., Xie, Y., Tu, Y., Oberley-Deegan, R. E., Batra, S. K. & Lin, M. F., Jun 2018, In : Cellular Signalling. 46, p. 1-14 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pancreatic cancer cells resistance to gemcitabine: The role of MUC4 mucin

Bafna, S., Kaur, S., Momi, N. & Batra, S. K., 2009, In : British journal of cancer. 101, 7, p. 1155-1161 7 p.

Research output: Contribution to journalArticle

65 Scopus citations

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

Costa-Silva, B., Aiello, N. M., Ocean, A. J., Singh, S., Zhang, H., Thakur, B. K., Becker, A., Hoshino, A., Mark, M. T., Molina, H., Xiang, J., Zhang, T., Theilen, T. M., García-Santos, G., Williams, C., Ararso, Y., Huang, Y., Rodrigues, G., Shen, T. L., Labori, K. J. & 17 others, Lothe, I. M. B., Kure, E. H., Hernandez, J., Doussot, A., Ebbesen, S. H., Grandgenett, P. M., Hollingsworth, M. A., Jain, M., Mallya, K., Batra, S. K., Jarnagin, W. R., Schwartz, R. E., Matei, I., Peinado, H., Stanger, B. Z., Bromberg, J. & Lyden, D., Jun 1 2015, In : Nature Cell Biology. 17, 6, p. 816-826 11 p.

Research output: Contribution to journalArticle

976 Scopus citations

Pancreatic cancer metastasis: Are we being pre-EMTed?

Das, S. & Batra, S. K., Jan 1 2015, In : Current Pharmaceutical Design. 21, 10, p. 1249-1255 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Pancreatic Enzyme Extract Improves Survival in Murine Pancreatic Cancer

Saruc, M., Standop, S., Standop, J., Nozawa, F., Itami, A., Pandey, K. K., Batra, S. K., Gonzalez, N. J., Guesry, P. & Pour, P. M., May 2004, In : Pancreas. 28, 4, p. 401-412 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pathobiological implications of MUC16/CA125 expression in intrahepatic cholangiocarcinoma-mass forming type

Higashi, M., Yamada, N., Yokoyama, S., Kitamoto, S., Tabata, K., Koriyama, C., Batra, S. K. & Yonezawa, S., Feb 2012, In : Pathobiology. 79, 2, p. 101-106 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Pathobiological implications of MUC16 expression in pancreatic cancer

Haridas, D., Chakraborty, S., Ponnusamy, M. P., Lakshmanan, I., Rachagani, S., Cruz, E., Kumar, S., Das, S., Lele, S. M., Anderson, J. M., Wittel, U. A., Hollingsworth, M. A. & Batra, S. K., Nov 4 2011, In : PloS one. 6, 10, e26839.

Research output: Contribution to journalArticle

73 Scopus citations

Pathobiological implications of MUC4 in non-small-cell lung cancer

Majhi, P. D., Lakshmanan, I., Ponnusamy, M. P., Jain, M., Das, S., Kaur, S., Shimizu, S. T., West, W. W., Johansson, S. L., Smith, L. M., Yu, F., Rolle, C. E., Sharma, P., Carey, G. B., Batra, S. K. & Ganti, A. K., Apr 2013, In : Journal of Thoracic Oncology. 8, 4, p. 398-407 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Pathobiological implications of mucin (MUC) expression in the outcome of small bowel cancer

Shibahara, H., Higashi, M., Koriyama, C., Yokoyama, S., Kitazono, I., Kurumiya, Y., Narita, M., Kuze, S., Kyokane, T., Mita, S., Arai, T., Kato, T., Yuasa, N., Yamaguchi, R., Kubota, H., Suzuki, H., Baba, S., Rousseau, K., Batra, S. K. & Yonezawa, S., Apr 10 2014, In : PloS one. 9, 4, e86111.

Research output: Contribution to journalArticle

7 Scopus citations

Pathobiological implications of the expression of EGFR, pAkt, NF-κB and MIC-1 in prostate cancer stem cells and their progenies

Mimeault, M., Johansson, S. L. & Batra, S. K., Feb 23 2012, In : PloS one. 7, 2, e31919.

Research output: Contribution to journalArticle

41 Scopus citations

Pathological and functional significance of Semaphorin-5A in pancreatic cancer progression and metastasis

Saxena, S., Hayashi, Y., Wu, L., Awaji, M., Atri, P., Varney, M. L., Purohit, A., Rachagani, S., Batra, S. K. & Singh, R. K., 2018, In : Oncotarget. 9, 5, p. 5931-5943 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Pathologic Features of Mucin-producing Bile Duct Tumors: Two Histopathologic Categories as Counterparts of Pancreatic Intraductal Papillary-mucinous Neoplasms

Shibahara, H., Tamada, S., Goto, M., Oda, K., Nagino, M., Nagasaka, T., Batra, S. K., Hollingsworth, M. A., Imai, K., Nimura, Y. & Yonezawa, S., Mar 2004, In : American Journal of Surgical Pathology. 28, 3, p. 327-338 12 p.

Research output: Contribution to journalArticle

141 Scopus citations

PD2/Paf1 depletion in pancreatic acinar cells promotes acinarto-ductal metaplasia

Dey, P., Rachagani, S., Vaz, A. P., Ponnusamy, M. P. & Batra, S. K., 2014, In : Oncotarget. 5, 12, p. 4480-4491 12 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Penetratin improves tumor retention of single-chain antibodies: A novel step toward optimization of radioimmunotherapy of solid tumors

Jain, M., Chauhan, S. C., Singh, A. P., Venkatraman, G., Colcher, D. & Batra, S. K., Sep 1 2005, In : Cancer Research. 65, 17, p. 7840-7846 7 p.

Research output: Contribution to journalArticle

75 Scopus citations

Pharmacokinetics and biodistribution of 177Lu-labeled multivalent single-chain Fv construct of the pancarcinoma monoclonal antibody CC49

Chauhan, S. C., Jain, M., Moore, E. D., Wittel, U. A., Li, J., Gwilt, P. R., Colcher, D. & Batra, S. K., Mar 2005, In : European Journal of Nuclear Medicine and Molecular Imaging. 32, 3, p. 264-273 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Pharmacokinetics and biodistribution of a light-chain-shuffled CC49 single-chain Fv antibody construct

Pavlinkova, G., Colcher, D., Booth, B. J. M., Goel, A. & Batra, S. K., 2000, In : Cancer Immunology Immunotherapy. 49, 4-5, p. 267-275 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Pharmacokinetics and biodistribution of engineered single-chain antibody constructs of MAb CC49 in colon carcinoma xenografts

Pavlinkova, G., Beresford, G. W., Booth, B. J. M., Batra, S. K. & Colcher, D., Sep 1999, In : Journal of Nuclear Medicine. 40, 9, p. 1536-1546 11 p.

Research output: Contribution to journalArticle

101 Scopus citations

Phosphorylation of Cx43 residue Y313 by Src contributes to blocking the interaction with Drebrin and disassembling gap junctions

Zheng, L., Li, H., Cannon, A., Trease, A. J., Spagnol, G., Zheng, H., Radio, S., Patel, K., Batra, S. & Sorgen, P. L., Jan 2019, In : Journal of Molecular and Cellular Cardiology. 126, p. 36-49 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Polyplex-mediated inhibition of chemokine receptor CXCR4 and chromatin-remodeling enzyme NCOA3 impedes pancreatic cancer progression and metastasis

Wang, Y., Kumar, S., Rachagani, S., Sajja, B. R., Xie, Y., Hang, Y., Jain, M., Li, J., Boska, M. D., Batra, S. K. & Oupický, D., Sep 1 2016, In : Biomaterials. 101, p. 108-120 13 p.

Research output: Contribution to journalArticle

11 Scopus citations