Surinder Kumar Batra, PhD

  • 21495 Citations
  • 75 h-Index
1985 …2020

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Potentials of Plasma NGAL and MIC-1 as Biomarker(s) in the Diagnosis of Lethal Pancreatic Cancer

Kaur, S., Chakraborty, S., Baine, M. J., Mallya, K., Smith, L. M., Sasson, A., Brand, R., Guha, S., Jain, M., Wittel, U., Singh, S. K. & Batra, S. K., Feb 1 2013, In : PloS one. 8, 2, e55171.

Research output: Contribution to journalArticle

38 Scopus citations

PR55α regulatory subunit of PP2A inhibits the MOB1/LATS cascade and activates YAP in pancreatic cancer cells

Hein, A. L., Brandquist, N. D., Ouellette, C. Y., Seshacharyulu, P., Enke, C. A., Ouellette, M. M., Batra, S. K. & Yan, Y., Nov 1 2019, In : Oncogenesis. 8, 11, 63.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

PR55α subunit of protein phosphatase 2A supports the tumorigenic and metastatic potential of pancreatic cancer cells by sustaining hyperactive oncogenic signaling

Hein, A. L., Seshacharyulu, P., Rachagani, S., Sheinin, Y. M., Ouellette, M. M., Ponnusamy, M. P., Mumby, M. C., Batra, S. K. & Yan, Y., Apr 15 2016, In : Cancer Research. 76, 8, p. 2243-2253 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Precision medicine and actionable alterations in lung cancer: A single institution experience

Mambetsariev, I., Wang, Y., Chen, C., Nadaf, S., Pharaon, R., Fricke, J., Amanam, I., Amini, A., Bild, A., Chu, P., Erhunmwunsee, L., Kim, J., Munu, J., Pillai, R., Raz, D., Sampath, S., Vora, L., Qiu, F., Smith, L., Batra, S. K. & 4 others, Massarelli, E., Koczywas, M., Reckamp, K. & Salgia, R., Feb 1 2020, In : PloS one. 15, 2, e0228188.

Research output: Contribution to journalArticle

Open Access

Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning

Yokoyama, S., Hamada, T., Higashi, M., Matsuo, K., Maemura, K., Kurahara, H., Horinouchi, M., Hiraki, T., Sugimoto, T., Akahane, T., Yonezawa, S., Kornmann, M., Batra, S. K., Hollingsworth, M. A. & Tanimoto, A., May 15 2020, In : Clinical Cancer Research. 26, 10, p. 2411-2421 11 p.

Research output: Contribution to journalArticle

Presence and structure-activity relationship of intrinsically disordered regions across mucins

Carmicheal, J., Atri, P., Sharma, S., Kumar, S., Chirravuri Venkata, R., Kulkarni, P., Salgia, R., Ghersi, D., Kaur, S. & Batra, S. K., Feb 1 2020, In : FASEB Journal. 34, 2, p. 1939-1957 19 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Progesterone decreases the responsiveness of ovine pituitary cultures to luteinizing hormone-releasing hormone

Batra, S. K., Miller, W. L. & Miller, W. L., Oct 1985, In : Endocrinology. 117, 4, p. 1436-1440 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

Progesterone inhibits basal production of follicle-stimulating hormone in ovine pituitary cell culture

Batra, S. K. & Miller, W. L., 1985, In : Endocrinology. 117, 6, p. 2443-2448 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Prognostic implications of chromosome 17p deletions in human medulloblastomas

Batra, S. K., McLendon, R. E., Koo, J. S., Castelino-Prabhu, S., Fuchs, H. E., Krischer, J. P., Friedman, H. S., Bigner, D. D. & Bigner, S. H., Feb 1995, In : Journal of Neuro-Oncology. 24, 1, p. 39-45 7 p.

Research output: Contribution to journalArticle

122 Scopus citations

Progressive multifocal leukoencephalopathy in a HIV-negative patient with small lymphocytic leukemia following treatment with rituximab

Chakraborty, S., Tarantolo, S. R., Treves, J., Sambol, D., Hauke, R. J. & Batra, S. K., Jan 2011, In : Case Reports in Oncology. 4, 1, p. 136-142 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Prostate-derived factor as a paracrine and autocrine factor for the proliferation of androgen receptor-positive human prostate cancer cells

Chen, S. J., Karan, D., Johansson, S. L., Lin, F. F., Zeckser, J., Singh, A. P., Batra, S. K. & Lin, M. F., Apr 1 2007, In : Prostate. 67, 5, p. 557-571 15 p.

Research output: Contribution to journalArticle

58 Scopus citations

PTTG1: a Unique Regulator of Stem/Cancer Stem Cells in the Ovary and Ovarian Cancer

Parte, S., Virant-Klun, I., Patankar, M., Batra, S. K., Straughn, A. & Kakar, S. S., Dec 1 2019, In : Stem Cell Reviews and Reports. 15, 6, p. 866-879 14 p.

Research output: Contribution to journalArticle

Purification and characterization of a human pancreatic adenocarcinoma mucin

Khorrami, A. M., Choudhury, A., Andrianifahanana, M., Varshney, G. C., Bhattacharyya, S. N., Hollingsworth, M. A., Kaufman, B. & Batra, S. K., 2002, In : Journal of Biochemistry. 131, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment

Hein, A. L., Post, C. M., Sheinin, Y. M., Lakshmanan, I., Natarajan, A., Enke, C. A., Batra, S. K., Ouellette, M. M. & Yan, Y., Dec 8 2016, In : Oncogene. 35, 49, p. 6319-6329 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Radioimmunotherapy of human colon cancer xenografts using a dimeric single-chain Fv antibody construct

Pavlinkova, G., Booth, B. J. M., Batra, S. K. & Colcher, D., Sep 1999, In : Clinical Cancer Research. 5, 9, p. 2613-2619 7 p.

Research output: Contribution to journalArticle

34 Scopus citations
196 Scopus citations
1 Scopus citations

Recent progress on tissue-resident adult stem cell biology and their therapeutic implications

Mimeault, M. & Batra, S. K., Mar 2008, In : Stem Cell Reviews. 4, 1, p. 27-49 23 p.

Research output: Contribution to journalArticle

131 Scopus citations

Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII)

Chu, C. T., Everiss, K. D., Wikstrand, C. J., Batra, S. K., Kung, H. J. & Bigner, D. D., Jun 15 1997, In : Biochemical Journal. 324, 3, p. 855-861 7 p.

Research output: Contribution to journalArticle

152 Scopus citations

Relative position of the hexahistidine tag effects binding properties of a tumor-associated single-chain Fv construct

Goel, A., Colcher, D., Koo, J. S., Booth, B. J. M., Pavlinkova, G. & Batra, S. K., Sep 1 2000, In : Biochimica et Biophysica Acta - General Subjects. 1523, 1, p. 13-20 8 p.

Research output: Contribution to journalArticle

82 Scopus citations

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: A multi-center evaluation

Gurumurthy, C. B., O'Brien, A. R., Quadros, R. M., Adams, J., Alcaide, P., Ayabe, S., Ballard, J., Batra, S. K., Beauchamp, M. C., Becker, K. A., Bernas, G., Brough, D., Carrillo-Salinas, F., Chan, W., Chen, H., Dawson, R., Demambro, V., D'Hont, J., Dibb, K. M., Eudy, J. D. & 93 others, Gan, L., Gao, J., Gonzales, A., Guntur, A. R., Guo, H., Harms, D. W., Harrington, A., Hentges, K. E., Humphreys, N., Imai, S., Ishii, H., Iwama, M., Jonasch, E., Karolak, M., Keavney, B., Khin, N. C., Konno, M., Kotani, Y., Kunihiro, Y., Lakshmanan, I., Larochelle, C., Lawrence, C. B., Li, L., Lindner, V., Liu, X. D., Lopez-Castejon, G., Loudon, A., Lowe, J., Jerome-Majewska, L. A., Matsusaka, T., Miura, H., Miyasaka, Y., Morpurgo, B., Motyl, K., Nabeshima, Y. I., Nakade, K., Nakashiba, T., Nakashima, K., Obata, Y., Ogiwara, S., Ouellet, M., Oxburgh, L., Piltz, S., Pinz, I., Ponnusamy, M. P., Ray, D., Redder, R. J., Rosen, C. J., Ross, N., Ruhe, M. T., Ryzhova, L., Salvador, A. M., Alam, S. S., Sedlacek, R., Sharma, K., Smith, C., Staes, K., Starrs, L., Sugiyama, F., Takahashi, S., Tanaka, T., Trafford, A. W., Uno, Y., Vanhoutte, L., Vanrockeghem, F., Willis, B. J., Wright, C. S., Yamauchi, Y., Yi, X., Yoshimi, K., Zhang, X., Zhang, Y., Ohtsuka, M., Das, S., Garry, D. J., Hochepied, T., Thomas, P., Parker-Thornburg, J., Adamson, A. D., Yoshiki, A., Schmouth, J. F., Golovko, A., Thompson, W. R., Lloyd, K. C. K., Wood, J. A., Cowan, M., Mashimo, T., Mizuno, S., Zhu, H., Kasparek, P., Liaw, L., Miano, J. M. & Burgio, G., Aug 26 2019, In : Genome biology. 20, 1, 171.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Retinoic acid-dependent transforming growth factor-β2-mediated induction of MUC4 mucin expression in human pancreatic tumor cells follows retinoic acid receptor-α signaling pathway

Choudhury, A., Singh, R. K., Moniaux, N., El-Metwally, T. H., Aubert, J. P. & Batra, S. K., Oct 27 2000, In : Journal of Biological Chemistry. 275, 43, p. 33929-33936 8 p.

Research output: Contribution to journalArticle

65 Scopus citations

Retinoids regulate the formation and degradation of gap junctions in androgen-responsive human prostate cancer cells

Kelsey, L., Katoch, P., Johnson, K. E., Batra, S. K. & Mehta, P. P., Apr 13 2012, In : PloS one. 7, 4, e32846.

Research output: Contribution to journalArticle

18 Scopus citations

RNA polymerase II associated factor 1/PD2 maintains self-renewal by its interaction with Oct3/4 in mouse embryonic stem cells

Ponnusamy, M. P., Deb, S., Dey, P., Chakraborty, S., Rachagani, S., Senapati, S. & Batra, S. K., Dec 2009, In : STEM CELLS. 27, 12, p. 3001-3011 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Role of MUC4-NIDO domain in the MUC4-mediated metastasis of pancreatic cancer cells

Senapati, S., Gnanapragassam, V. S., Moniaux, N., Momi, N. & Batra, S. K., Jul 12 2012, In : Oncogene. 31, 28, p. 3346-3356 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

RXRα: A novel target for prostate cancer

Pandey, K. K. & Batra, S. K., Mar 2003, In : Cancer Biology and Therapy. 2, 2, p. 185-186 2 p.

Research output: Contribution to journalArticle

Secreted semaphorin 5A suppressed pancreatic tumour burden but increased metastasis and endothelial cell proliferation

Sadanandam, A., Sidhu, S. S., Wullschleger, S., Singh, S., Varney, M. L., Yang, C. S., Ashour, A. E., Batra, S. K. & Singh, R. K., Jul 24 2012, In : British journal of cancer. 107, 3, p. 501-507 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95

Das, A., Durrant, D., Mitchell, C., Dent, P., Batra, S. K. & Kukreja, R. C., 2016, In : Oncotarget. 7, 4, p. 4399-4413 15 p.

Research output: Contribution to journalArticle

15 Scopus citations

Single-chain antibodies in pancreatic cancer

Colcher, D., Pavlinkova, G., Beresford, G., Booth, B. J. M. & Batra, S. K., 1999, In : Annals of the New York Academy of Sciences. 880, p. 263-280 18 p.

Research output: Contribution to journalArticle

33 Scopus citations

Single-dose versus fractionated radioimmunotherapy of human colon carcinoma xenografts using 131I-labeled multivalent CC49 single-chain Fvs1

Goel, A., Augustine, S., Baranowska-Kortylewicz, J., Colcher, D., Booth, B. J. M., Pavlinkova, G., Tempero, M. & Batra, S. K., 2001, In : Clinical Cancer Research. 7, 1, p. 175-184 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing HB-EGF expression in macrophages

Kumar, S., Torres, M. P., Kaur, S., Rachagani, S., Joshi, S., Johansson, S. L., Momi, N., Baine, M. J., Gilling, C. E., Smith, L. M., Wyatt, T. A., Jain, M., Joshi, S. S. & Batra, S. K., Jun 9 2014, In : Oncogene. 34, 16, p. 2052-2060 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Statin derivatives as therapeutic agents for castration-resistant prostate cancer

Ingersoll, M. A., Miller, D. R., Martinez, O., Wakefield, C. B., Hsieh, K. C., Simha, M. V., Kao, C. L., Chen, H. T., Batra, S. K. & Lin, M. F., Dec 1 2016, In : Cancer Letters. 383, 1, p. 94-105 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Suppression of ErbB-2 in androgen-independent human prostate cancer cells enhances cytotoxic effect by gemcitabine in an androgen-reduced environment

Zhang, L., Davis, J. S., Zelivianski, S., Lin, F. F., Schutte, R., Davis, T. L., Hauke, R., Batra, S. K. & Lin, M. F., Nov 18 2009, In : Cancer Letters. 285, 1, p. 58-65 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Synergistic induction of the MUC4 mucin gene by interferon-γ and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways

Andrianifahanana, M., Agrawal, A., Singh, A. P., Moniaux, N., Van Seuningen, I., Aubert, J. P., Meza, J. & Batra, S. K., Sep 8 2005, In : Oncogene. 24, 40, p. 6143-6154 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Systems Biology Approach to Identify Novel Genomic Determinants for Pancreatic Cancer Pathogenesis

Khatri, I., Ganguly, K., Sharma, S., Carmicheal, J., Kaur, S., Batra, S. K. & Bhasin, M. K., Dec 1 2019, In : Scientific reports. 9, 1, 123.

Research output: Contribution to journalArticle

3 Scopus citations

Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer

Seshacharyulu, P., Ponnusamy, M. P., Rachagani, S., Lakshmanan, I., Haridas, D., Yan, Y., Ganti, A. K. & Batra, S. K., 2015, In : Oncotarget. 6, 7, p. 5164-5181 18 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Targeting the IκB Kinase Enhancer and Its Feedback Circuit in Pancreatic Cancer

Challa, S., Husain, K., Kim, R., Coppola, D., Batra, S. K., Cheng, J. Q. & Malafa, M. P., Feb 2020, In : Translational Oncology. 13, 2, p. 481-489 9 p.

Research output: Contribution to journalArticle

Open Access

Taurocholate-induced pancreatitis: A model of severe necrotizing pancreatitis in mice

Wittel, U. A., Wiech, T., Chakraborty, S., Boss, B., Lauch, R., Batra, S. K. & Hopt, U. T., Mar 2008, In : Pancreas. 36, 2, p. e9-e21

Research output: Contribution to journalArticle

42 Scopus citations

TET1-mediated DNA hypomethylation regulates the expression of MUC4 in lung cancer

Yokoyama, S., Higashi, M., Tsutsumida, H., Wakimoto, J., Hamada, T., Wiest, E., Matsuo, K., Kitazono, I., Goto, Y., Guo, X., Hamada, T., Yamada, S., Hiraki, T., Yonezawa, S., Batra, S. K., Hollingsworth, M. A. & Tanimoto, A., Mar 2017, In : Genes and Cancer. 8, 3-4, p. 517-527 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma

Pai, P., Rachagani, S., Lakshmanan, I., Macha, M. A., Sheinin, Y., Smith, L. M., Ponnusamy, M. P. & Batra, S. K., Feb 1 2016, In : Molecular Oncology. 10, 2, p. 224-239 16 p.

Research output: Contribution to journalArticle

16 Scopus citations

The human homologue of the RNA polymerase II-associated factor 1 (hPaf1), localized on the 19q13 amplicon, is associated with tumorigenesis

Moniaux, N., Nemos, C., Schmied, B. M., Chauhan, S. C., Deb, S., Morikane, K., Choudhury, A., VanLith, M., Sutherlin, M., Sikela, J. M., Hollingsworth, M. A. & Batra, S. K., Jun 1 2006, In : Oncogene. 25, 23, p. 3247-3257 11 p.

Research output: Contribution to journalArticle

54 Scopus citations

The human PAF complex coordinates transcription with events downstream of RNA synthesis

Zhu, B., Mandal, S. S., Pham, A. D., Zheng, Y., Erdjument-Bromage, H., Batra, S. K., Tempst, P. & Reinberg, D., Jul 2005, In : Genes and Development. 19, 14, p. 1668-1673 6 p.

Research output: Contribution to journalArticle

141 Scopus citations

The human RNA polymerase II-associated factor 1 (hPaf1): A new regulator of cell-cycle progression

Moniaux, N., Nemos, C., Deb, S., Zhu, B., Dornreiter, I., Hollingsworth, M. A. & Batra, S. K., Sep 22 2009, In : PloS one. 4, 9, e7077.

Research output: Contribution to journalArticle

21 Scopus citations

The in vivo characteristics of genetically engineered divalent and tetravalent single-chain antibody constructs

Wittel, U. A., Jain, M., Goel, A., Chauhan, S. C., Colcher, D. & Batra, S. K., Feb 2005, In : Nuclear Medicine and Biology. 32, 2, p. 157-164 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

The pattern of xenobiotic-metabolizing enzymes in the human pancreas

Standop, J., Schneider, M. B., Ulrich, A., Chauhan, S., Moniaux, N., Büchler, M. W., Batra, S. K. & Pour, P. M., Oct 11 2002, In : Journal of Toxicology and Environmental Health - Part A. 65, 19, p. 1379-1400 22 p.

Research output: Contribution to journalArticle

13 Scopus citations

The small heat shock protein α A-crystallin is expressed in pancreas and acts as a negative regulator of carcinogenesis

Deng, M., Chen, P. C., Xie, S., Zhao, J., Gong, L., Liu, J., Zhang, L., Sun, S., Liu, J., Ma, H., Batra, S. K. & Li, D. W. C., Jul 2010, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1802, 7-8, p. 621-631 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

TLR4 activation by lipopolysaccharide confers survival advantage to growth factor deprived prostate cancer cells

Jain, S., Suklabaidya, S., Das, B., Raghav, S. K., Batra, S. K. & Senapati, S., Jul 1 2015, In : Prostate. 75, 10, p. 1020-1033 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

Transcriptional profiling of peripheral blood mononuclear cells in pancreatic cancer patients identifies novel genes with potential diagnostic utility

Baine, M. J., Chakraborty, S., Smith, L. M., Mallya, K., Sasson, A. R., Brand, R. E. & Batra, S. K., 2011, In : PloS one. 6, 2, e17014.

Research output: Contribution to journalArticle

69 Scopus citations