Surinder Kumar Batra, PhD

  • 20980 Citations
  • 74 h-Index
1985 …2020

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2014

Altered expression of transmembrane mucins, MUC1 and MUC4, in bladder cancer: Pathological implications in diagnosis

Kaur, S., Momi, N., Chakraborty, S., Wagner, D. G., Horn, A. J., Lele, S. M., Theodorescu, D. & Batra, S. K., Mar 26 2014, In : PloS one. 9, 3, e92742.

Research output: Contribution to journalArticle

23 Scopus citations
32 Scopus citations

Altered Mucins (MUC) trafficking in Benign and malignant conditions

Joshi, S., Kumar, S., Choudhury, A., Ponnusamy, M. P. & Batra, S. K., 2014, In : Oncotarget. 5, 17, p. 7272-7284 13 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Breast cancer survival of Hispanic women in the USA is influenced by country of origin

Chakraborty, S., Smith, L., Ganti, A. K., Bonthu, N., Shimizhu, T. & Batra, S. K., 2014, In : Asia-Pacific Journal of Clinical Oncology. 10, 2, p. 124-132 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Diagnosis of pancreatic neoplasms using a novel method of DNA methylation analysis of mucin expression in pancreatic juice

Yokoyama, S., Kitamoto, S., Higashi, M., Goto, Y., Hara, T., Ikebe, D., Yamaguchi, T., Arisaka, Y., Niihara, T., Nishimata, H., Tanaka, S., Takaori, K., Batra, S. K. & Yonezawa, S., Apr 8 2014, In : PloS one. 9, 4, e93760.

Research output: Contribution to journalArticle

18 Scopus citations

Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation

Yan, Y., Hein, A. L., Etekpo, A., Burchett, K. M., Lin, C., Enke, C. A., Batra, S. K., Cowan, K. H. & Ouellette, M. M., 2014, In : Oncotarget. 5, 21, p. 10251-10270 20 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Membrane-bound mucins and mucin terminal glycans expression in idiopathic or Helicobacter pylori, NSAID associated peptic ulcers

Niv, Y., Boltin, D., Halpern, M., Cohen, M., Levi, Z., Vilkin, A., Morgenstern, S., Manugian, V., St Lawrence, E., Gagneux, P., Kaur, S., Sharma, P., Batra, S. K. & Ho, S. B., Oct 28 2014, In : World Journal of Gastroenterology. 20, 40, p. 14913-14920 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

MicroRNAs (miRNAs) as biomarker(s) for prognosis and diagnosis of gastrointestinal (GI) cancers

Macha, M. A., Seshacharyulu, P., Krishn, S. R., Pai, P., Rachagani, S., Jain, M. & Batra, S. K., 2014, In : Current Pharmaceutical Design. 20, 33, p. 5287-5297 11 p.

Research output: Contribution to journalArticle

39 Scopus citations

MUC4-mediated regulation of acute phase protein lipocalin 2 through HER2/AKT/NF-κB signaling in pancreatic cancer

Kaur, S., Sharma, N., Krishn, S. R., Lakshmanan, I., Rachagani, S., Baine, M. J., Smith, L. M., Lele, S. M., Sasson, A. R., Guha, S., Mallya, K., Anderson, J. M., Hollingsworth, M. A. & Batra, S. K., 2014, In : Clinical Cancer Research. 20, 3, p. 688-700 13 p.

Research output: Contribution to journalArticle

22 Scopus citations
21 Scopus citations

Pathobiological implications of mucin (MUC) expression in the outcome of small bowel cancer

Shibahara, H., Higashi, M., Koriyama, C., Yokoyama, S., Kitazono, I., Kurumiya, Y., Narita, M., Kuze, S., Kyokane, T., Mita, S., Arai, T., Kato, T., Yuasa, N., Yamaguchi, R., Kubota, H., Suzuki, H., Baba, S., Rousseau, K., Batra, S. K. & Yonezawa, S., Apr 10 2014, In : PloS one. 9, 4, e86111.

Research output: Contribution to journalArticle

7 Scopus citations

PD2/Paf1 depletion in pancreatic acinar cells promotes acinarto-ductal metaplasia

Dey, P., Rachagani, S., Vaz, A. P., Ponnusamy, M. P. & Batra, S. K., 2014, In : Oncotarget. 5, 12, p. 4480-4491 12 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing HB-EGF expression in macrophages

Kumar, S., Torres, M. P., Kaur, S., Rachagani, S., Joshi, S., Johansson, S. L., Momi, N., Baine, M. J., Gilling, C. E., Smith, L. M., Wyatt, T. A., Jain, M., Joshi, S. S. & Batra, S. K., Jun 9 2014, In : Oncogene. 34, 16, p. 2052-2060 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation.

Souchek, J. J., Baine, M. J., Lin, C., Rachagani, S., Gupta, S., Kaur, S., Lester, K., Zheng, D., Chen, S., Smith, L. M., Lazenby, A. J., Johansson, S. L., Jain, M. & Batra, S. K., Sep 9 2014, In : British journal of cancer. 111, 6, p. 1139-1149 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Withaferin a alone and in combination with cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells

Kakar, S. S., Ratajczak, M. Z., Powell, K. S., Moghadamfalahi, M., Miller, D. M., Batra, S. K. & Singh, S. K., Sep 29 2014, In : PloS one. 9, 9, e107596.

Research output: Contribution to journalArticle

49 Scopus citations
2013

Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer

Lin, W. C., Rajbhandari, N., Liu, C., Sakamoto, K., Zhang, Q., Triplett, A. A., Batra, S. K., Opavsky, R., Felsher, D. W., DiMaio, D. J., Hollingsworth, M. A., Morris IV, J. P., Hebrok, M., Witkiewicz, A. K., Brody, J. R., Rui, H. & Wagner, K. U., Mar 15 2013, In : Cancer Research. 73, 6, p. 1821-1830 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Expression of MUC4 mucin is observed mainly in the intestinal type of intraductal papillary mucinous neoplasm of the pancreas

Kitazono, I., Higashi, M., Kitamoto, S., Yokoyama, S., Horinouchi, M., Osako, M., Shimizu, T., Tabata, M., Batra, S. K., Goto, M. & Yonezawa, S., Oct 2013, In : Pancreas. 42, 7, p. 1120-1128 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling

Macha, M. A., Rachagani, S., Gupta, S., Pai, P., Ponnusamy, M. P., Batra, S. K. & Jain, M., Dec 1 2013, In : Cancer Letters. 341, 2, p. 166-177 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Holy Basil leaf extract decreases tumorigenicity and metastasis of aggressive human pancreatic cancer cells in vitro and in vivo: Potential role in therapy

Shimizu, T., Torres, M. P., Chakraborty, S., Souchek, J. J., Rachagani, S., Kaur, S., Macha, M. A., Ganti, A. K., Hauke, R. J. & Batra, S. K., Aug 19 2013, In : Cancer Letters. 336, 2, p. 270-280 11 p.

Research output: Contribution to journalArticle

25 Scopus citations
190 Scopus citations

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology

Horn, A., Chakraborty, S., Dey, P., Haridas, D., Souchek, J., Batra, S. K. & Lele, S. M., Apr 2013, In : Archives of Pathology and Laboratory Medicine. 137, 4, p. 546-551 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Impaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway

Pandey, P., Seshacharyulu, P., Das, S., Rachagani, S., Ponnusamy, M. P., Yan, Y., Johansson, S. L., Datta, K., Lin, M. F. & Batra, S. K., Jun 25 2013, In : British journal of cancer. 108, 12, p. 2590-2600 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Incidence and prognostic significance of second primary cancers in renal cell carcinoma

Chakraborty, S., Tarantolo, S. R., Batra, S. K. & Hauke, R. J., Apr 2013, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 36, 2, p. 132-142 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
20 Scopus citations
30 Scopus citations

MUC4 Overexpression Augments Cell Migration and Metastasis through EGFR Family Proteins in Triple Negative Breast Cancer Cells

Mukhopadhyay, P., Lakshmanan, I., Ponnusamy, M. P., Chakraborty, S., Jain, M., Pai, P., Smith, L. M., Lele, S. M. & Batra, S. K., Feb 11 2013, In : PloS one. 8, 2, e54455.

Research output: Contribution to journalArticle

41 Scopus citations

Neutrophil gelatinase-associated lipocalin, macrophage inhibitory cytokine 1, and carbohydrate antigen 19-9 in pancreatic juice: Pathobiologic implications in diagnosing benign and malignant disease of the pancreas

Kaur, S., Baine, M. J., Guha, S., Ochi, N., Chakraborty, S., Mallya, K., Thomas, C., Crook, J., Wallace, M. B., Woodward, T. A., Jain, M., Singh, S., Sasson, A. R., Skinner, V., Raimondo, M. & Batra, S. K., Apr 2013, In : Pancreas. 42, 3, p. 494-501 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through α7nAChR-mediated MUC4 upregulation

Momi, N., Ponnusamy, M. P., Kaur, S., Rachagani, S., Kunigal, S. S., Chellappan, S., Ouellette, M. M. & Batra, S. K., Mar 14 2013, In : Oncogene. 32, 11, p. 1384-1395 12 p.

Research output: Contribution to journalArticle

77 Scopus citations

Novel pancreatic cancer cell lines derived from genetically engineered mouse models of spontaneous pancreatic adenocarcinoma: Applications in diagnosis and therapy

Torres, M. P., Rachagani, S., Souchek, J. J., Mallya, K., Johansson, S. L. & Batra, S. K., Nov 20 2013, In : PloS one. 8, 11, e80580.

Research output: Contribution to journalArticle

51 Scopus citations

Pathobiological implications of MUC4 in non-small-cell lung cancer

Majhi, P. D., Lakshmanan, I., Ponnusamy, M. P., Jain, M., Das, S., Kaur, S., Shimizu, S. T., West, W. W., Johansson, S. L., Smith, L. M., Yu, F., Rolle, C. E., Sharma, P., Carey, G. B., Batra, S. K. & Ganti, A. K., Apr 2013, In : Journal of Thoracic Oncology. 8, 4, p. 398-407 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Potentials of Plasma NGAL and MIC-1 as Biomarker(s) in the Diagnosis of Lethal Pancreatic Cancer

Kaur, S., Chakraborty, S., Baine, M. J., Mallya, K., Smith, L. M., Sasson, A., Brand, R., Guha, S., Jain, M., Wittel, U., Singh, S. K. & Batra, S. K., Feb 1 2013, In : PloS one. 8, 2, e55171.

Research output: Contribution to journalArticle

37 Scopus citations
2012

DF3 epitope expression on MUC1 mucin is associated with tumor aggressiveness, subsequent lymph node metastasis, and poor prognosis in patients with oral squamous cell carcinoma

Hamada, T., Nomura, M., Kamikawa, Y., Yamada, N., Batra, S. K., Yonezawa, S. & Sugihara, K., Nov 1 2012, In : Cancer. 118, 21, p. 5251-5264 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Expression of MUC17 is regulated by HIF1α -mediated hypoxic responses and requires a methylation-free hypoxia responsible element in pancreatic cancer

Kitamoto, S., Yokoyama, S., Higashi, M., Yamada, N., Matsubara, S., Takao, S., Batra, S. K. & Yonezawa, S., Sep 10 2012, In : PloS one. 7, 9, e44108.

Research output: Contribution to journalArticle

13 Scopus citations

Graviola: A novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism

Torres, M. P., Rachagani, S., Purohit, V., Pandey, P., Joshi, S., Moore, E. D., Johansson, S. L., Singh, P. K., Ganti, A. K. & Batra, S. K., Oct 1 2012, In : Cancer Letters. 323, 1, p. 29-40 12 p.

Research output: Contribution to journalArticle

84 Scopus citations

Membrane-bound mucins and mucin terminal glycans expression in idiopathic or helicobacter pylori, NSAID associated peptic ulcers

Niv, Y., Boltin, D., Halpern, M., Cohen, M., Levi, Z., Vilkin, A., Morgenstern, S., Manugian, V., Lawrence, E. S., Gagneux, P., Batra, S. K. & Ho, S. B., Oct 2012, In : Digestive Diseases and Sciences. 57, 10, p. 2535-2544 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

MUC16 induced rapid G2/M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cells

Lakshmanan, I., Ponnusamy, M. P., Das, S., Chakraborty, S., Haridas, D., Mukhopadhyay, P., Lele, S. M. & Batra, S. K., Feb 16 2012, In : Oncogene. 31, 7, p. 805-817 13 p.

Research output: Contribution to journalArticle

72 Scopus citations

MUC4: A novel prognostic factor of oral squamous cell carcinoma

Hamada, T., Wakamatsu, T., Miyahara, M., Nagata, S., Nomura, M., Kamikawa, Y., Yamada, N., Batra, S. K., Yonezawa, S. & Sugihara, K., Apr 15 2012, In : International Journal of Cancer. 130, 8, p. 1768-1776 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

MUC4 and MUC1 Expression in Adenocarcinoma of the Stomach Correlates with Vessel Invasion and Lymph Node Metastasis: An Immunohistochemical Study of Early Gastric Cancer

Tamura, Y., Higashi, M., Kitamoto, S., Yokoyama, S., Osako, M., Horinouchi, M., Shimizu, T., Tabata, M., Batra, S. K., Goto, M. & Yonezawa, S., Nov 13 2012, In : PloS one. 7, 11, e49251.

Research output: Contribution to journalArticle

33 Scopus citations
49 Scopus citations

Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: Potential implications for diagnosis and therapy

Rachagani, S., Torres, M. P., Kumar, S., Haridas, D., Baine, M., Macha, M. A., Kaur, S., Ponnusamy, M. P., Dey, P., Seshacharyulu, P., Johansson, S. L., Jain, M., Wagner, K. U. & Batra, S. K., 2012, In : Journal of Hematology and Oncology. 5, 68.

Research output: Contribution to journalArticle

40 Scopus citations
19 Scopus citations

Overexpression of ecdysoneless in pancreatic cancer and its role in oncogenesis by regulating glycolysis

Dey, P., Rachagani, S., Chakraborty, S., Singh, P. K., Zhao, X., Gurumurthy, C. B., Anderson, J. M., Lele, S., Hollingsworth, M. A., Band, V. & Batra, S. K., Nov 15 2012, In : Clinical Cancer Research. 18, 22, p. 6188-6198 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Pathobiological implications of MUC16/CA125 expression in intrahepatic cholangiocarcinoma-mass forming type

Higashi, M., Yamada, N., Yokoyama, S., Kitamoto, S., Tabata, K., Koriyama, C., Batra, S. K. & Yonezawa, S., Feb 2012, In : Pathobiology. 79, 2, p. 101-106 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Pathobiological implications of the expression of EGFR, pAkt, NF-κB and MIC-1 in prostate cancer stem cells and their progenies

Mimeault, M., Johansson, S. L. & Batra, S. K., Feb 23 2012, In : PloS one. 7, 2, e31919.

Research output: Contribution to journalArticle

41 Scopus citations

Retinoids regulate the formation and degradation of gap junctions in androgen-responsive human prostate cancer cells

Kelsey, L., Katoch, P., Johnson, K. E., Batra, S. K. & Mehta, P. P., Apr 13 2012, In : PloS one. 7, 4, e32846.

Research output: Contribution to journalArticle

18 Scopus citations

Role of MUC4-NIDO domain in the MUC4-mediated metastasis of pancreatic cancer cells

Senapati, S., Gnanapragassam, V. S., Moniaux, N., Momi, N. & Batra, S. K., Jul 12 2012, In : Oncogene. 31, 28, p. 3346-3356 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Secreted semaphorin 5A suppressed pancreatic tumour burden but increased metastasis and endothelial cell proliferation

Sadanandam, A., Sidhu, S. S., Wullschleger, S., Singh, S., Varney, M. L., Yang, C. S., Ashour, A. E., Batra, S. K. & Singh, R. K., Jul 24 2012, In : British journal of cancer. 107, 3, p. 501-507 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Upregulation of mucin4 in ER-positive/HER2-overexpressing breast cancer xenografts with acquired resistance to endocrine and HER2-targeted therapies

Chen, A. C., Migliaccio, I., Rimawi, M., Lopez-Tarruella, S., Creighton, C. J., Massarweh, S., Huang, C., Wang, Y. C., Batra, S. K., Gutierrez, M. C., Kent Osborne, C. & Schiff, R., Jul 2012, In : Breast Cancer Research and Treatment. 134, 2, p. 583-593 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011
54 Scopus citations

Detection of the potential pancreatic cancer marker MUC4 in serum using surface-enhanced Raman scattering

Wang, G., Lipert, R. J., Jain, M., Kaur, S., Chakraboty, S., Torres, M. P., Batra, S. K., Brand, R. E. & Porter, M. D., Apr 1 2011, In : Analytical chemistry. 83, 7, p. 2554-2561 8 p.

Research output: Contribution to journalArticle

156 Scopus citations