Tadayoshi Bessho, PhD

  • 2054 Citations
  • 20 h-Index
1986 …2020

Research output per year

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Research Output

  • 2054 Citations
  • 20 h-Index
  • 42 Article
  • 2 Comment/debate
  • 2 Review article
2020

Kinesin Kif2C in regulation of DNA double strand break dynamics and repair

Zhu, S., Paydar, M., Wang, F., Li, Y., Wang, L., Barrette, B., Bessho, T., Kwok, B. H. & Peng, A., Jan 2020, In : eLife. 9, e53402.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Participation of TDP1 in the repair of formaldehyde-induced DNA-protein crosslinks in chicken DT40 cells

Nakano, T., Shoulkamy, M. I., Tsuda, M., Sasanuma, H., Hirota, K., Takata, M., Masunaga, S. I., Takeda, S., Ide, H., Bessho, T. & Tano, K., Jun 2020, In : PloS one. 15, 6 June, e0234859.

Research output: Contribution to journalArticle

Open Access
2019

Aberrations in DNA repair pathways in cancer and therapeutic significances

Motegi, A., Masutani, M., Yoshioka, K. I. & Bessho, T., Oct 2019, In : Seminars in Cancer Biology. 58, p. 29-46 18 p.

Research output: Contribution to journalReview article

10 Scopus citations

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI

Hu, W. F., Krieger, K. L., Lagundžin, D., Li, X., Cheung, R. S., Taniguchi, T., Johnson, K. R., Bessho, T., Monteiro, A. N. A. & Woods, N. T., Dec 1 2019, In : Cell Death Discovery. 5, 1, 105.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Inactivation of XPF Sensitizes Cancer Cells to Gemcitabine

George, J. W., Bessho, M. & Bessho, T., 2019, In : Journal of Nucleic Acids. 2019, 6357609.

Research output: Contribution to journalArticle

Open Access
2018

Correction: KSR1 is required for cell cycle reinitiation following DNA damage.(Journal of Biological Chemistry (2018)284 (6705– 6715))

Razidlo, G. L., Johnson, H. J., Stoeger, S. M., Cowan, K. H., Bessho, T. & Lewis, R. E., Dec 7 2018, In : Journal of Biological Chemistry. 293, 49, p. 19136 1 p.

Research output: Contribution to journalComment/debate

2017

MUC1-mediated metabolic alterations regulate response to radiotherapy in pancreatic cancer

Gunda, V., Souchek, J., Abrego, J., Shukla, S. K., Goode, G. D., Vernucci, E., Dasgupta, A., Chaika, N. V., King, R. J., Li, S., Wang, S., Yu, F., Bessho, T., Lin, C. & Singh, P. K., Oct 1 2017, In : Clinical Cancer Research. 23, 19, p. 5881-5891 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining

Zhu, S., Fisher, L. A., Bessho, T. & Peng, A., Oct 1 2017, In : Nucleic acids research. 45, 18, p. 10583-10594 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Impact of DNA repair pathways on the cytotoxicity of piperlongumine in chicken DT40 cell-lines

Okamoto, S., Narita, T., Sasanuma, H., Takeda, S., Masunaga, S. I., Bessho, T. & Tano, K., 2014, In : Genes and Cancer. 5, 7-8, p. 285-292 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Bypass of a psoralen DNA interstrand cross-link by DNA polymerases β, l, and κ in Vitro

Smith, L. A., Makarova, A. V., Samson, L., Thiesen, K. E., Dhar, A. & Bessho, T., Nov 6 2012, In : Biochemistry. 51, 44, p. 8931-8938 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
24 Scopus citations
2011

Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA Polymerase iota

Makarova, A. V., Grabow, C., Gening, L. V., Tarantul, V. Z., Tahirov, T. H., Bessho, T. & Pavlov, Y. I., 2011, In : PloS one. 6, 1, e16612.

Research output: Contribution to journalArticle

20 Scopus citations

Removal of reactive oxygen species-induced 3′-blocked ends by XPF-ERCC1

Fisher, L. A., Samson, L. & Bessho, T., Nov 21 2011, In : Chemical Research in Toxicology. 24, 11, p. 1876-1881 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Role of interaction of XPF with RPA in nucleotide excision repair

Fisher, L. A., Bessho, M., Wakasugi, M., Matsunaga, T. & Bessho, T., Oct 21 2011, In : Journal of Molecular Biology. 413, 2, p. 337-346 10 p.

Research output: Contribution to journalArticle

13 Scopus citations
2009

Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links

Zietlow, L., Smith, L. A., Bessho, M. & Bessho, T., Dec 15 2009, In : Biochemistry. 48, 49, p. 11817-11824 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

KSR1 is required for cell cycle reinitiation following DNA Damage

Razidlo, G. L., Johnson, H. J., Stoeger, S. M., Cowan, K. H., Bessho, T. & Lewis, R. E., Mar 13 2009, In : Journal of Biological Chemistry. 284, 11, p. 6705-6715 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
2008

DNA polymerase I-mediated translesion synthesis in RecA-independent DNA interstrand cross-link Repair in E. coli

Zietlow, L. & Bessho, T., May 13 2008, In : Biochemistry. 47, 19, p. 5460-5464 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Processing of a psoralen DNA interstrand cross-link by XPF-ERCC1 complex in vitro

Fisher, L. A., Bessho, M. & Bessho, T., Jan 18 2008, In : Journal of Biological Chemistry. 283, 3, p. 1275-1281 7 p.

Research output: Contribution to journalArticle

52 Scopus citations
2006

The role of BRCA2 in replication-coupled DNA interstrand cross-link repair in vitro

Cipak, L., Watanabe, N. & Bessho, T., Aug 2006, In : Nature Structural and Molecular Biology. 13, 8, p. 729-733 5 p.

Research output: Contribution to journalArticle

38 Scopus citations
2004

Physical and Functional Interaction between the XPF/ERCC1 Endonuclease and hRad52

Motycka, T. A., Bessho, T., Post, S. M., Sung, P. & Tomkinson, A. E., Apr 2 2004, In : Journal of Biological Chemistry. 279, 14, p. 13634-13639 6 p.

Research output: Contribution to journalArticle

55 Scopus citations
2003

Induction of DNA replication-mediated double strand breaks by psoralen DNA interstrand cross-links

Bessho, T., Feb 14 2003, In : Journal of Biological Chemistry. 278, 7, p. 5250-5254 5 p.

Research output: Contribution to journalArticle

69 Scopus citations
2000

DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts

Mu, D., Bessho, T., Nechev, L. V., Chen, D. J., Harris, T. M., Hearst, J. E. & Sancar, A., Apr 2000, In : Molecular and cellular biology. 20, 7, p. 2446-2454 9 p.

Research output: Contribution to journalArticle

112 Scopus citations

Human DNA damage checkpoint protein hRAD9 is a 3' to 5' exonuclease

Bessho, T. & Sancar, A., Mar 17 2000, In : Journal of Biological Chemistry. 275, 11, p. 7451-7454 4 p.

Research output: Contribution to journalArticle

65 Scopus citations
1999
88 Scopus citations
1998

Nucleotide excision repair of melphalan monoadducts

Grant, D. F., Bessho, T. & Reardon, J. T., Nov 15 1998, In : Cancer Research. 58, 22, p. 5196-5200 5 p.

Research output: Contribution to journalArticle

26 Scopus citations
1997

Characterization of the XPF endonuclease complex

McCutchen-Maloney, S. L., Hwang, M., Bessho, T., Sancar, A. & Thelen, M. P., 1997, In : FASEB Journal. 11, 9, p. A1371

Research output: Contribution to journalArticle

Open Access
108 Scopus citations
304 Scopus citations

Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex

Bessho, T., Sancar, A., Thompson, L. H. & Thelen, M. P., 1997, In : Journal of Biological Chemistry. 272, 6, p. 3833-3837 5 p.

Research output: Contribution to journalArticle

154 Scopus citations
1996

Replication protein A confers structure-specific endonuclease activities to the XPF-ERCC1 and XPG subunits of human DNA repair excision nuclease

Matsunaga, T., Park, C. H., Bessho, T., Mu, D. & Sancar, A., 1996, In : Journal of Biological Chemistry. 271, 19, p. 11047-11050 4 p.

Research output: Contribution to journalArticle

152 Scopus citations
1995

Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease

Park, C. H., Bessho, T., Matsunaga, T. & Sancar, A., 1995, In : Journal of Biological Chemistry. 270, 39, p. 22657-22660 4 p.

Research output: Contribution to journalArticle

107 Scopus citations
1994

Nucleoside and nucleobase analog mutagens

Negishi, K., Bessho, T. & Hayatsu, H., Dec 1994, In : Mutation Research/Reviews in Genetic Toxicology. 318, 3, p. 227-238 12 p.

Research output: Contribution to journalReview article

18 Scopus citations
1993

Evidence for two DNA repair enzymes for 8-hydroxyguanine (7,8-dihydro-8- oxoguanine) in human cells

Bessho, T., Tano, K., Kasai, H., Ohtsuka, E. & Nishimura, S., 1993, In : Journal of Biological Chemistry. 268, 26, p. 19416-19421 6 p.

Research output: Contribution to journalArticle

182 Scopus citations
19 Scopus citations

Repair of 8-hydroxyguanine in DNA by mammalian N-methylpurine-DNA glycosylase

Bessho, T., Roy, R., Yamamoto, K., Kasai, H., Nishimura, S., Tano, K. & Mitra, S., Oct 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 19, p. 8901-8904 4 p.

Research output: Contribution to journalArticle

Open Access
135 Scopus citations
1992

Analysis of phage M13mp2 mutants produced from transfection of phage DNA having N4-aminocytosines at defined sequence positions

Matsumoto, K., Yashiki, T., Bessho, T., Negishi, K. & Hayatsu, H., Jul 1992, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 268, 1, p. 59-64 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Blockage of polymerase-catalyzed DNA chain elongation by chemiscally modified cytosine residues in templates and the release of blockage for readthrough

Bessho, T., Nitta, N., Negishi, K. & Hayatsu, H., Aug 25 1992, In : Nucleic acids research. 20, 16, p. 4213-4220 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
43 Scopus citations

Photosensitized formation of 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in DNA by riboflavin.

Kasai, H., Yamaizumi, Z., Yamamoto, F., Bessho, T., Nishimura, S., Berger, M. & Cadet, J., 1992, In : Nucleic acids symposium series. 27, p. 181-182 2 p.

Research output: Contribution to journalArticle

20 Scopus citations

Ubiquitous Presence in Mammalian Cells of Enzymatic Activity Specifically Cleaving 8‐Hydroxyguanine‐containing DNA

Yamamoto, F., Kasai, H., Bessho, T., Chung, MH. H., Inoue, H., Ohtsuka, E., Hori, T. & Nishimura, S., Apr 1992, In : Japanese Journal of Cancer Research. 83, 4, p. 351-357 7 p.

Research output: Contribution to journalArticle

85 Scopus citations
1990

Probing salt-induced and supercoiling-induced B-Z junctions in DNA by bisulfitemethoxyamine.

Negishi, K., Yamashita, T., Zacharias, W., Wells, R. D., Bessho, T. & Hayatsu, H., 1990, In : Nucleic acids symposium series. 22, p. 109-110 2 p.

Research output: Contribution to journalArticle

1989

Modification of 5-methylcytosine in DNA and its relation to mutagenesis.

Negishi, K., Harada, Y., Atsumi, G., Bessho, T., Negishi, T. & Hayatsu, H., 1989, In : Nucleic acids symposium series. 21, p. 111-112 2 p.

Research output: Contribution to journalArticle

Spectrum of N4-aminocytidine mutagenesis

Bessho, T., Matsumoto, K., Nomura, A., Hayatsu, H. & Negishi, K., Feb 20 1989, In : Journal of Molecular Biology. 205, 4, p. 659-664 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
1988

In vitro mutagenesis by incorporation of N4-aminodeoxycytidine 5'-triphosphate.

Negishi, K., Matsumoto, K., Bessho, T., Tada, F. & Hayatsu, H., 1988, In : Nucleic acids symposium series. 19, p. 33-36 4 p.

Research output: Contribution to journalArticle

3 Scopus citations
1986

Inhibition of DNA chain elongation by N4-aminocytosine-bisulfite adduct on template.

Negishi, K., Bessho, T., Nishizawa, M., Kawakami, M. & Hayatsu, H., 1986, In : Nucleic acids symposium series. 17, p. 139-140 2 p.

Research output: Contribution to journalArticle