Thomas L McDonald, PhD, DVM

  • 2087 Citations
  • 23 h-Index
1970 …2018

Research output per year

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Research Output

  • 2087 Citations
  • 23 h-Index
  • 74 Article
  • 1 Chapter
2018

Creatinine downregulates TNF-α in macrophage and T cell lines

Riesberg, L. A., McDonald, T. L., Wang, Y., Chen, X. M., Holzmer, S. W., Tracy, S. M. & Drescher, K. M., Oct 2018, In : Cytokine. 110, p. 29-38 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Serum amyloid A1 (SAA1) protein in human colostrum

Sack, G. H., Zachara, N., Rosenblum, N., Talbot, C. C., Kreimer, S., Cole, R. & McDonald, T. L., Mar 2018, In : FEBS Open Bio. 8, 3, p. 435-441 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Beyond muscles: The untapped potential of creatine

Riesberg, L. A., Weed, S. A., McDonald, T. L., Eckerson, J. M. & Drescher, K. M., Aug 1 2016, In : International Immunopharmacology. 37, p. 31-42 12 p.

Research output: Contribution to journalArticle

15 Scopus citations
2014

A novel, broadly applicable approach to isolation of fungi in diverse growth media

Smithee, S., Tracy, S., Drescher, K. M., Pitz, L. A. & McDonald, T., Oct 2014, In : Journal of Microbiological Methods. 105, p. 155-161 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2012

Creatinine inhibits bacterial replication

McDonald, T., Drescher, K. M., Weber, A. & Tracy, S., Mar 2012, In : Journal of Antibiotics. 65, 3, p. 153-156 4 p.

Research output: Contribution to journalArticle

6 Scopus citations
2011

Effect of creatine, creatinine, and creatine ethyl ester on TLR expression in macrophages

Leland, K. M., McDonald, T. L. & Drescher, K. M., Sep 2011, In : International Immunopharmacology. 11, 9, p. 1341-1347 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
2009

Evaluation of colostrum-derived human mammary-associated serum amyloid A3 (M-SAA3) protein and peptide derivatives for the prevention of enteric infection: In vitro and in murine models of intestinal disease

Gardiner, G. E., O'Flaherty, S., Casey, P. G., Weber, A., McDonald, T. L., Cronin, M., Hill, C., Ross, R. P., Gahan, C. G. M. & Shanahan, F., Apr 2009, In : FEMS Immunology and Medical Microbiology. 55, 3, p. 404-413 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2007

Robust expression of a bioactive mammalian protein in Chlamydomonas chloroplast

Manuell, A. L., Beligni, M. V., Elder, J. H., Siefker, D. T., Tran, M., Weber, A., McDonald, T. L. & Mayfield, S. P., May 2007, In : Plant Biotechnology Journal. 5, 3, p. 402-412 11 p.

Research output: Contribution to journalArticle

123 Scopus citations
2006
11 Scopus citations
32 Scopus citations
2005
44 Scopus citations
2003

Human serum amyloid A3 peptide enhances intestinal MUC3 expression and inhibits EPEC adherence

Larson, M. A., Wei, S. H., Weber, A., Mack, D. R. & McDonald, T. L., Jan 10 2003, In : Biochemical and Biophysical Research Communications. 300, 2, p. 531-540 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Induction of human mammary-associated serum amyloid A3 expression by prolactin or lipopolysaccharide

Larson, M. A., Wei, S. H., Weber, A., Weber, A. T. & McDonald, T. L., Feb 21 2003, In : Biochemical and Biophysical Research Communications. 301, 4, p. 1030-1037 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

The conserved TFLK motif of mammary-associated serum amyloid A3 is responsible for up-regulation of intestinal MUC3 mucin expression in vitro

Mack, D. R., McDonald, T. L., Larson, M. A., Wei, S. & Weber, A., Jan 1 2003, In : Pediatric Research. 53, 1, p. 137-142 6 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations
2001

Acute phase proteins in serum and milk from dairy cows with clinical mastitis

Eckersall, P. D., Young, F. J., McComb, C., Hogarth, C. J., Safi, S., Weber, A., McDonald, T., Nolan, A. M. & Fitzpatrick, J. L., Jan 13 2001, In : Veterinary Record. 148, 2, p. 35-41 7 p.

Research output: Contribution to journalArticle

239 Scopus citations
160 Scopus citations
1998

Monoclonal and polyclonal antibodies recognizing acetaldehyde-protein adducts

Thiele, G. M., Tuma, D. J., Miller, J. A., Wegter, K. M., McDonald, T. L. & Klassen, L. W., Dec 1 1998, In : Biochemical Pharmacology. 56, 11, p. 1515-1523 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Soluble proteins modified with acetaldehyde and malondialdehyde are immunogenic in the absence of adjuvant

Thiele, G. M., Tuma, D. J., Willis, M. S., Miller, J. A., McDonald, T. L., Sorrell, M. F. & Klassen, L. W., Nov 1998, In : Alcoholism: Clinical and Experimental Research. 22, 8, p. 1731-1739 9 p.

Research output: Contribution to journalArticle

83 Scopus citations
1996
1 Scopus citations

Immunologic attributes of cytokine mobilized peripheral blood stem cells and recovery following transplantation

Talmadge, J. E., Reed, E. C., Kessinger, A., Kuszynski, C. A., Perry, G. A., Gordy, C. L., Mills, K. C., Thomas, M. L., Pirruccello, S. J., Letheby, B. A., Arneson, M. A. & Jackson, J. D., Jan 1996, In : Bone marrow transplantation. 17, 1, p. 101-109 9 p.

Research output: Contribution to journalArticle

84 Scopus citations

Regulation and characterization of the interferon-α present in patients with advanced human immunodeficiency virus type 1 disease

Swindells, S., Baldwin, T., Kelly, C., Baca-Regen, L., Loomis, L., Post, D., Brichacek, B., Stevenson, M., Dominguez, E. A., Reddy, R., Klein, R., Liao, M. J., Testa, D., Mcdonald, T., Bellanti, J., Skurkovich, S. & Gendelman, H. E., Feb 1996, In : Journal of Interferon and Cytokine Research. 16, 2, p. 127-137 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
1994

Detection of Reduced Acetaldehyde Protein Adducts Using a Unique Monoclonal Antibody

Klassen, L. W., Tuma, D. J., Sorrell, M. F., McDonald, T. L., DeVasure, J. M. & Thiele, G. M., Feb 1994, In : Alcoholism: Clinical and Experimental Research. 18, 1, p. 164-171 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
14 Scopus citations
1993

Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection

Bukrinsky, M. I., Sharova, N., Mcdonald, T. L., Pushkarskaya, T., Tarpley, W. G. & Stevenson, M., Jul 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 13, p. 6125-6129 5 p.

Research output: Contribution to journalArticle

Open Access
370 Scopus citations

Clinical and immunologic studies in reticular erythematous mucinosis and Jessner's lymphocytic infiltrate of skin

Braddock, S. W., Kay, H. D., Maennle, D., McDonald, T. L., Pirruccello, S. J., Masih, A., Klassen, L. W. & Sawka, A. R., 1993, In : Journal of the American Academy of Dermatology. 28, 5, p. 691-695 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Glomerular injury in end-stage liver disease - role of circulating IgG and IgM immune complexes

Milner, L. S., Houser, M. T., Kolbeck, P. C., Antonson, D. L., McDonald, T. L., Markin, R. S. & Shaw, B. W., Feb 1993, In : Pediatric Nephrology. 7, 1, p. 6-10 5 p.

Research output: Contribution to journalArticle

15 Scopus citations
1992
28 Scopus citations
2 Scopus citations
49 Scopus citations
1991

A monoclonal antibody sandwich immunoassay for serum amyloid A (SAA) protein

McDonald, T. L., Weber, A. & Smith, J. W., Nov 22 1991, In : Journal of Immunological Methods. 144, 2, p. 149-155 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

Use of ethanol-eluted hydrophobic interaction chromatography in the purification of serum amyloid A

Smith, J. W. & McDonald, T. L., 1991, In : Protein Expression and Purification. 2, 2-3, p. 158-161 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
1990

An enzyme‐linked immunosorbent assay for the detection of antitetanus toxoid antibody using aluminum‐absorbed coating antigen

Thiele, G. M., Rogers, J., Collins, M., Smith, D., McDonald, T. L. & Yasuda, N., 1990, In : Journal of Clinical Laboratory Analysis. 4, 2, p. 126-129 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Autonomous growth of lymphoid cells following IL-2 expression from retrovirus vectors containing HIV-1 trans-acting elements

Shapiro, I. M., Meier, C., Vlach, V., McDonald, T. L., Wigzell, H. & Stevenson, M., Jan 1990, In : Somatic Cell and Molecular Genetics. 16, 1, p. 1-14 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Construction and use of a template block for radial immunodiffusion

McDonald, T. L., Weber, A. & Thiele, G., Apr 1990, In : Analytical Biochemistry. 186, 1, p. 165-168 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
1 Scopus citations
1989

IgG subclasses in gingival crevicular fluid from active versus stable periodontal sites.

Reinhardt, R. A., McDonald, T. L., Bolton, R. W., DuBois, L. M. & Kaldahl, W. B., Jan 1989, In : Journal of periodontology. 60, 1, p. 44-50 7 p.

Research output: Contribution to journalArticle

58 Scopus citations

Injury induces increase of von Willebrand factor in rat endothelial cells

Reidy, M. A., Chopek, M., Chao, S., McDonald, T. & Schwartz, S. M., 1989, In : American Journal of Pathology. 134, 4, p. 857-864 8 p.

Research output: Contribution to journalArticle

58 Scopus citations
1988

In situ activated T lymphocytes in active versus stable periodontal lesions

Reinhardt, R. A., McDonald, T. L., Bolton, R. W., DuBois, L. M., Feely, D. E. & Kaldahl, W. B., Sep 1988, In : Journal of Periodontal Research. 23, 5, p. 295-302 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

In situ lymphocyte subpopulations from active versus stable periodontal sites.

Reinhardt, R. A., Bolton, R. W., McDonald, T. L., DuBois, L. M. & Kaldahl, W. B., Oct 1988, In : Journal of periodontology. 59, 10, p. 656-670 15 p.

Research output: Contribution to journalArticle

68 Scopus citations
15 Scopus citations
1987
2 Scopus citations

Isolation and characterization of circulating immune complexes from patients with pneumococcal pneumonia.

Mellencamp, M. A., Preheim, L. C. & McDonald, T. L., Aug 1987, In : Infection and immunity. 55, 8, p. 1737-1742 6 p.

Research output: Contribution to journalArticle

15 Scopus citations
1986

Circulating immune complexes in cystic fibrosis and their correlation to clinical parameters

Disis, M. L., McDonald, T. L., Colombo, J. L., Kobayashi, R. H., Angle, C. R. & Murray, S., May 1986, In : Pediatric Research. 20, 5, p. 385-390 6 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Interaction between canine platelets and adult heartworms: platelet recognition of heartworm surfaces.

Clemmons, R. M., Yamaguchi, R. A., Schaub, R. G., Fleming, J., Dorsey-Lee, M. R. & McDonald, T. L., Feb 1986, In : American journal of veterinary research. 47, 2, p. 322-325 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Proliferation of human peripheral blood lymphocytes induced by recombinant human interleukin 2: Contribution of large granular lymphocytes and T lymphocytes

Talmadge, J. E., Wiltrout, R. H., Counts, D. F., Herberman, R. B., McDonald, T. & Ortaldo, J. R., Oct 15 1986, In : Cellular Immunology. 102, 2, p. 261-272 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Prospective study of familial canine dermatomyositis. Correlation of the severity of dermatomyositis and circulating immune complex levels

Hargis, A. M., Prieur, D. J., Haupt, K. H., McDonald, T. L. & Moore, M. P., 1986, In : American Journal of Pathology. 123, 3, p. 465-479 15 p.

Research output: Contribution to journalArticle

24 Scopus citations
1985

Accelerated onset of albuminuria in diabetic rats preimmunized with glucosylated rat serum albumin

Bassiouny, A. R., Rosenberg, H., Thiele, G. M. & McDonald, T. L., 1985, In : Journal of Clinical and Laboratory Immunology. 18, 2, p. 69-73 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Animal model for the study of diabetic autoimmunity involving glucosylated proteins

Rosenberg, H., Bassiouny, A., Thiele, G. & McDonald, T. L., 1985, In : Federation Proceedings. 44, 3, p. No. 1142

Research output: Contribution to journalArticle

Correlation of circulating immune complexes with onset and severity of dermatomyositis in collies

Hargis, A. M., McDonald, T. L. & Prieur, D. J., 1985, In : Federation Proceedings. 44, 3, p. No. 655

Research output: Contribution to journalArticle

Familial canine dermatomyositis: clinicopathologic, immunologic, and serologic studies.

Haupt, K. H., Prieur, D. J., Hargis, A. M., Cowell, R. L., McDonald, T. L., Werner, L. L. & Evermann, J. F., Sep 1985, In : American journal of veterinary research. 46, 9, p. 1870-1875 6 p.

Research output: Contribution to journalArticle

28 Scopus citations