• 6595 Citations
  • 45 h-Index
1988 …2020

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Article
2020

Effect of Doxycycline on Aneurysm Growth among Patients with Small Infrarenal Abdominal Aortic Aneurysms: A Randomized Clinical Trial

Baxter, B. T., Matsumura, J., Curci, J. A., McBride, R., Larson, L., Blackwelder, W., Lam, D., Wijesinha, M. & Terrin, M., May 26 2020, In : JAMA - Journal of the American Medical Association. 323, 20, p. 2029-2038 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome

Jespersen, K., Liu, Z., Li, C., Harding, P., Sestak, K., Batra, R., Stephenson, C. A., Foley, R. T., Greene, H., Meisinger, T., Baxter, B. T. & Xiong, W., Dec 1 2020, In : Scientific reports. 10, 1, 10949.

Research output: Contribution to journalArticle

Open Access

Ex vivo expansion of regulatory T cells from abdominal aortic aneurysm patients inhibits aneurysm in humanized murine model

Suh, M. K., Batra, R., Carson, J. S., Xiong, W., Dale, M. A., Meisinger, T., Killen, C., Mitchell, J. & Baxter, B. T., 2020, (Accepted/In press) In : Journal of vascular surgery.

Research output: Contribution to journalArticle

Open Access
2019

CD95-ligand contributes to abdominal aortic aneurysm progression by modulating inflammation

Liu, Z., Fitzgerald, M., Meisinger, T., Batra, R., Suh, M., Greene, H., Penrice, A. J., Sun, L., Baxter, B. T. & Xiong, W., Mar 15 2019, In : Cardiovascular research. 115, 4, p. 807-818 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

IL-1β (Interleukin-1β) and TNF-α (Tumor Necrosis Factor-α) Impact Abdominal Aortic Aneurysm Formation by Differential Effects on Macrophage Polarization

Batra, R., Suh, M. K., Carson, J. S., Dale, M. A., Meisinger, T. M., Fitzgerald, M., Opperman, P. J., Luo, J., Pipinos, I. I., Xiong, W. & Baxter, B. T., Feb 1 2018, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 2, p. 457-463 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

In vitro measurements of hemodynamic forces and their effects on endothelial cell mechanics at the sub-cellular level

Lambert, L. M., Pipinos, I. I., Baxter, B. T., Chatzizisis, Y. S., Ryu, S. J., Leighton, R. I. & Wei, T., Nov 1 2018, In : Biomicrofluidics. 12, 6, 064101.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Premature aortic smooth muscle cell differentiation contributes to matrix dysregulation in Marfan Syndrome

Dale, M., Fitzgerald, M. P., Liu, Z., Meisinger, T., Karpisek, A., Purcell, L. N., Carson, J. S., Harding, P., Lang, H., Koutakis, P., Batra, R., Mietus, C. J., Casale, G., Pipinos, I., Baxter, B. T. & Xiong, W., Oct 2017, In : PloS one. 12, 10, e0186603.

Research output: Contribution to journalArticle

16 Scopus citations
2016
4 Scopus citations

Elastin-derived peptides promote abdominal aortic aneurysm formation by modulating m1/m2 macrophage polarization

Dale, M. A., Xiong, W., Carson, J. S., Suh, M. K., Karpisek, A. D., Meisinger, T. M., Casale, G. P. & Baxter, B. T., Jun 1 2016, In : Journal of Immunology. 196, 11, p. 4536-4543 8 p.

Research output: Contribution to journalArticle

42 Scopus citations
19 Scopus citations

Outcomes of aortic surgery for abdominal aortic graft infections

Gupta, P. K., Ramanan, B., Grossman, L., Gupta, H., Fang, X., MacTaggart, J. N., Lynch, T. G., Baxter, B. T. & Pipinos, I. I., 2016, In : Vascular and Endovascular Surgery. 50, 4, p. 256-260 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Recurrent Admissions for Respiratory Distress Caused by Large Renal AVF

Keller, W. W., Miserlis, D., Suh, M., Dale, M., Sayyed, S. & Baxter, B. T., Jan 1 2016, In : Vascular and Endovascular Surgery. 50, 1, p. 57-59 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Age and disease-related geometric and structural remodeling of the carotid artery

Kamenskiy, A. V., Pipinos, I. I., Carson, J. S., Mactaggart, J. N. & Baxter, B. T., Dec 2015, In : Journal of vascular surgery. 62, 6, p. 1521-1528 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Background differences in baseline and stimulated MMP levels influence abdominal aortic aneurysm susceptibility

Dale, M. A., Suh, M. K., Zhao, S., Meisinger, T., Gu, L., Swier, V. J., Agrawal, D. K., Greiner, T. C., Carson, J. S., Baxter, B. T. & Xiong, W., Dec 1 2015, In : Atherosclerosis. 243, 2, p. 621-629 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Inflammatory cell phenotypes in AAAs: Their role and potential as targets for therapy

Dale, M. A., Ruhlman, M. K. & Baxter, B. T., Aug 25 2015, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 8, p. 1746-1755 10 p.

Research output: Contribution to journalArticle

66 Scopus citations
2014

Three-dimensional bending, torsion and axial compression of the femoropopliteal artery during limb flexion

MacTaggart, J. N., Phillips, N. Y., Lomneth, C. S., Pipinos, I. I., Bowen, R., Timothy Baxter, B., Johanning, J., Matthew Longo, G., Desyatova, A. S., Moulton, M. J., Dzenis, Y. A. & Kamenskiy, A. V., Jul 18 2014, In : Journal of Biomechanics. 47, 10, p. 2249-2256 8 p.

Research output: Contribution to journalArticle

35 Scopus citations
2013

In-hospital and postdischarge venous thromboembolism after vascular surgery

Ramanan, B., Gupta, P. K., Sundaram, A., Lynch, T. G., MacTaggart, J. N., Baxter, B. T., Johanning, J. M. & Pipinos, I. I., Jun 2013, In : Journal of vascular surgery. 57, 6, p. 1589-1596 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
2012

Elevation of plasma high-density lipoproteins inhibits development of experimental abdominal aortic aneurysms

Torsney, E., Pirianov, G., Charolidi, N., Shoreim, A., Gaze, D., Petrova, S., Laing, K., Meisinger, T., Xiong, W., Baxter, B. T. & Cockerill, G. W., Nov 2012, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 32, 11, p. 2678-2686 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

MMP-2 Regulates Erk1/2 phosphorylation and aortic dilatation in marfan syndrome

Xiong, W., Meisinger, T., Knispel, R., Worth, J. M. & Baxter, B. T., Jun 8 2012, In : Circulation Research. 110, 12, p. e92-e101

Research output: Contribution to journalArticle

63 Scopus citations

MT1-MMP regulates the PI3Kδ-Mi-2/NuRD-dependent control of macrophage immune function

Shimizu-Hirota, R., Xiong, W., Baxter, B. T., Kunkel, S. L., Maillard, I., Chen, X. W., Sabeh, F., Liu, R., Li, X. Y. & Weiss, S. J., Feb 15 2012, In : Genes and Development. 26, 4, p. 395-413 19 p.

Research output: Contribution to journalArticle

52 Scopus citations
2010

Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: A systematic review and meta-analysis of observational studies

Kenet, G., Lütkhoff, L. K., Albisetti, M., Bernard, T., Bonduel, M., Brandao, L., Chabrier, S., Chan, A., Deveber, G., Fiedler, B., Fullerton, H. J., Goldenberg, N. A., Grabowski, E., Günther, G., Heller, C., Holzhauer, S., Iorio, A., Journeycake, J., Junker, R., Kirkham, F. J. & 13 others, Kurnik, K., Lynch, J. K., Male, C., Manco-Johnson, M., Mesters, R., Monagle, P., Van Ommen, C. H., Raffini, L., Rostásy, K., Simioni, P., Sträter, R. D., Young, G. & Nowak-Göttl, U., Apr 2010, In : Circulation. 121, 16, p. 1838-1847 10 p.

Research output: Contribution to journalArticle

261 Scopus citations
2009

Blocking TNF-α attenuates aneurysm formation in a murine Model

Xiong, W., MacTaggart, J., Knispel, R., Worth, J., Persidsky, Y. & Baxter, B. T., Aug 15 2009, In : Journal of Immunology. 183, 4, p. 2741-2746 6 p.

Research output: Contribution to journalArticle

106 Scopus citations

Inhibition of reactive oxygen species attenuates aneurysm formation in a murine model

Xiong, W., Mactaggart, J., Knispel, R., Worth, J., Zhu, Z., Li, Y., Sun, Y., Baxter, B. T. & Johanning, J., Jan 2009, In : Atherosclerosis. 202, 1, p. 128-134 7 p.

Research output: Contribution to journalArticle

81 Scopus citations
61 Scopus citations
2008

Chronically ischemic mouse skeletal muscle exhibits myopathy in association with mitochondrial dysfunction and oxidative damage

Pipinos, I. I., Swanson, S. A., Zhu, Z., Nella, A. A., Weiss, D. J., Gutti, T. L., McComb, R. D., Baxter, B. T., Lynch, T. G. & Casale, G. P., Jul 2008, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 295, 1, p. R290-R296

Research output: Contribution to journalArticle

55 Scopus citations

Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome

Xiong, W., Knispel, R. A., Dietz, H. C., Ramirez, F. & Baxter, B. T., Jan 2008, In : Journal of vascular surgery. 47, 1, p. 166-172 7 p.

Research output: Contribution to journalArticle

106 Scopus citations

Vascular management in rotationplasty

Mahoney, C. R., Hartman, C. W., Simon, P. J., Baxter, B. T. & Neff, J. R., May 2008, In : Clinical Orthopaedics and Related Research. 466, 5, p. 1210-1216 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2007

Concomitant Arterial and Venous Reconstruction with Resection of Lower Extremity Sarcomas

Baxter, B. T., Mahoney, C., Johnson, P. J., Selmer, K. M., Pipinos, I. I., Rose, J. & Neff, J. R., May 2007, In : Annals of Vascular Surgery. 21, 3, p. 272-279 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Deletion of CCR2 but not CCR5 or CXCR3 inhibits aortic aneurysm formation

MacTaggart, J. N., Xiong, W., Knispel, R. & Baxter, B. T., Aug 2007, In : Surgery. 142, 2, p. 284-288 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice

Sun, J., Sukhova, G. K., Yang, M., Wolters, P. J., MacFarlane, L. A., Libby, P., Sun, C., Zhang, Y., Liu, J., Ennis, T. L., Knispel, R., Xiong, W., Thompson, R. W., Baxter, B. T. & Shi, G. P., Nov 1 2007, In : Journal of Clinical Investigation. 117, 11, p. 3359-3368 10 p.

Research output: Contribution to journalArticle

168 Scopus citations
2006

Effects of tissue inhibitor of metalloproteinase 2 deficiency on aneurysm formation

Xiong, W., Knispel, R., Mactaggart, J. & Baxter, B. T., Nov 2006, In : Journal of vascular surgery. 44, 5, p. 1061-1066 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Localized administration of doxycycline suppresses aortic dilatation in an experimental mouse model of abdominal aortic aneurysm

Bartoli, M. A., Parodi, F. E., Chu, J., Pagano, M. B., Mao, D., Baxter, B. T., Buckley, C., Ennis, T. L. & Thompson, R. W., Mar 2006, In : Annals of Vascular Surgery. 20, 2, p. 228-236 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

Mitochondrial defects and oxidative damage in patients with peripheral arterial disease

Pipinos, I. I., Judge, A. R., Zhu, Z., Selsby, J. T., Swanson, S. A., Johanning, J. M., Baxter, B. T., Lynch, T. G. & Dodd, S. L., Jul 15 2006, In : Free Radical Biology and Medicine. 41, 2, p. 262-269 8 p.

Research output: Contribution to journalArticle

117 Scopus citations

MMP-9 microsatellite polymorphism and susceptibility to carotid arteries atherosclerosis

Fiotti, N., Altamura, N., Fisicaro, M., Carraro, N., Uxa, L., Grassi, G., Torelli, L., Gobbato, R., Guarnieri, G., Baxter, B. T. & Giansante, C., Jun 2006, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 26, 6, p. 1330-1336 7 p.

Research output: Contribution to journalArticle

33 Scopus citations
2005

MMP-12 has a role in abdominal aortic aneurysms in mice

Longo, G. M., Buda, S. J., Fiotta, N., Xiong, W., Griener, T., Shapiro, S. & Baxter, B. T., Apr 2005, In : Surgery. 137, 4, p. 457-462 6 p.

Research output: Contribution to journalArticle

106 Scopus citations

MMP-9 microsatellite polymorphism: Association with the progression of intima-media thickening and constrictive remodeling of carotid atherosclerotic plaques

Fiotti, N., Altamura, N., Fisicaro, M., Carraro, N., Adovasio, R., Sarra, V. M., Uxa, L., Guarnieri, G., Baxter, B. T. & Giansante, C., Oct 2005, In : Atherosclerosis. 182, 2, p. 287-292 6 p.

Research output: Contribution to journalArticle

22 Scopus citations
2004

Could medical intervention work for aortic aneurysms?

Baxter, B. T., Dec 2004, In : American journal of surgery. 188, 6, p. 628-632 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Elastin degradation and calcification in an abdominal aorta injury model: Role of matrix metalloproteinases

Basalyga, D. M., Simionescu, D. T., Xiong, W., Baxter, B. T., Starcher, B. C. & Vyavahare, N. R., Nov 30 2004, In : Circulation. 110, 22, p. 3480-3487 8 p.

Research output: Contribution to journalArticle

209 Scopus citations

Endograft technology: A delivery vehicle for intravascular gene therapy

Eton, D., Yu, H., Wang, Y., Raines, J., Striker, G., Livingstone, A. & Baxter, T., May 2004, In : Journal of vascular surgery. 39, 5, p. 1066-1073 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Key Roles of CD4+ T Cells and IFN-γ in the Development of Abdominal Aortic Aneurysms in a Murine Model

Xiong, W., Zhao, Y., Prall, A., Greiner, T. C. & Baxter, B. T., Feb 15 2004, In : Journal of Immunology. 172, 4, p. 2607-2612 6 p.

Research output: Contribution to journalArticle

Open Access
132 Scopus citations

Limb salvage after infrainguinal bypass graft failure

Baldwin, Z. K., Pearce, B. J., Curi, M. A., Desai, T. R., McKinsey, J. F., Bassiouny, H. S., Katz, D., Gewertz, B. L., Schwartz, L. B., Henke, P. K. & Baxter, T., May 2004, In : Journal of vascular surgery. 39, 5, p. 951-957 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

Presidential address: Commitment - Looking for someone willing to go to the trouble

Baxter, B. T., May 2004, In : Journal of vascular surgery. 39, 5, p. 925-930 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2003

Distal internal iliac artery embolization: A procedure to avoid

Kritpracha, B., Pigott, J. P., Price, C. I., Russell, T. E., Corbey, M. J., Beebe, H. G., Baxter, T., Blebea, J., Martinez, B., Massop, D. & McCarthy, W., May 1 2003, In : Journal of vascular surgery. 37, 5, p. 943-948 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

Fate of excluded popliteal artery aneurysms

Ebaugh, J. L., Morasch, M. D., Matsumura, J. S., Eskandari, M. K., Meadows, W. S., Pearce, W. H., d'Audiffret, A., Baxter, T., Turnipseed, B. & Flinn, W., May 1 2003, In : Journal of vascular surgery. 37, 5, p. 954-959 6 p.

Research output: Contribution to journalArticle

73 Scopus citations

Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells

Liu, J., Xiong, W., Baca-Regen, L., Nagase, H. & Baxter, B. T., Dec 2003, In : Journal of vascular surgery. 38, 6, p. 1376-1383 8 p.

Research output: Contribution to journalArticle

91 Scopus citations

Temporal patterns of postoperative complications

Thompson, J. S., Baxter, B. T., Allison, J. G., Johnson, F. E., Lee, K. K., Park, W. Y., Pickleman, J., Dayton, M. T., Jurkovich, G. J., Landercasper, J. & Thirlby, R. C., Jun 1 2003, In : Archives of Surgery. 138, 6, p. 596-603 8 p.

Research output: Contribution to journalArticle

67 Scopus citations

Xenogeneic skin graft rejection in M-CSF/macrophage deficient osteopetrotic mice

Zhao, Y., Xiong, W., Yang, T., Prall, A., Baxter, B. T. & Langnas, A. N., May 2003, In : Xenotransplantation. 10, 3, p. 232-239 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
2002

Angioplasty with stenting is effective in treating blue toe syndrome

Renshaw, A., McCowen, T., Waltke, E. A., Wattenhofer, S. P., Tahara, R. W. & Baxter, B. T., 2002, In : Vascular and Endovascular Surgery. 36, 2, p. 155-159 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Doxycycline in patients with abdominal aortic aneurysms and in mice: Comparison of serum levels and effect on aneurysm growth in mice

Prall, A. K., Longo, G. M., Mayhan, W. G., Waltke, E. A., Fleckten, B., Thompson, R. W. & Baxter, B. T., May 2002, In : Journal of vascular surgery. 35, 5, p. 923-929 7 p.

Research output: Contribution to journalArticle

157 Scopus citations