Tony Hollingsworth, PhD

  • 17676 Citations
  • 70 h-Index
1981 …2020

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2020

Comparative phenotypes of peripheral blood and spleen cells from cancer patients

Cole, K. E., Ly, Q. P., Hollingsworth, M. A., Cox, J. L., Stromnes, I. M., Padussis, J. C., Foster, J. M., Vargas, L. M. & Talmadge, J. E., Aug 2020, In : International Immunopharmacology. 85, 106655.

Research output: Contribution to journalArticle

Macrophages potentiate STAT3 signaling in skeletal muscles and regulate pancreatic cancer cachexia

Shukla, S. K., Markov, S. D., Attri, K. S., Vernucci, E., King, R. J., Dasgupta, A., Grandgenett, P. M., Hollingsworth, M. A., Singh, P. K., Yu, F. & Mehla, K., Aug 1 2020, In : Cancer Letters. 484, p. 29-39 11 p.

Research output: Contribution to journalArticle

Pan-cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In : Nature. 578, 7793, p. 82-93 12 p.

Research output: Contribution to journalArticle

Open Access
72 Scopus citations

Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning

Yokoyama, S., Hamada, T., Higashi, M., Matsuo, K., Maemura, K., Kurahara, H., Horinouchi, M., Hiraki, T., Sugimoto, T., Akahane, T., Yonezawa, S., Kornmann, M., Batra, S. K., Hollingsworth, M. A. & Tanimoto, A., May 15 2020, In : Clinical Cancer Research. 26, 10, p. 2411-2421 11 p.

Research output: Contribution to journalArticle

Radiomics-based outcome prediction for pancreatic cancer following stereotactic body radiotherapy

Parr, E., Du, Q., Zhang, C., Lin, C., Kamal, A., McAlister, J., Liang, X., Bavitz, K., Rux, G., Hollingsworth, M., Baine, M. & Zheng, D., Apr 2020, In : Cancers. 12, 4, 1051.

Research output: Contribution to journalArticle

Open Access

Sirt1–nox4 signaling axis regulates cancer cachexia

Dasgupta, A., Shukla, S. K., Vernucci, E., King, R. J., Abrego, J., Mulder, S. E., Mullen, N. J., Graves, G., Buettner, K., Thakur, R., Murthy, D., Attri, K. S., Wang, D., Chaika, N. V., Pacheco, C. G., Rai, I., Engle, D. D., Grandgenett, P. M., Punsoni, M., Reames, B. N. & 10 others, Teoh-Fitzgerald, M., Oberley-Deegan, R., Yu, F., Klute, K. A., Hollingsworth, M. A., Zimmerman, M. C., Mehla, K., Sadoshima, J., Tuveson, D. A. & Singh, P. K., Jul 6 2020, In : Journal of Experimental Medicine. 217, 7, e20190745.

Research output: Contribution to journalArticle

Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation

Somerville, T. D. D., Biffi, G., Daßler-Plenker, J., Hur, S. K., He, X. Y., Vance, K. E., Miyabayashi, K., Xu, Y., Maia-Silva, D., Klingbeil, O., Demerdash, O. E., Preall, J. B., Hollingsworth, M. A., Egeblad, M., Tuveson, D. A. & Vakoc, C. R., Apr 2020, In : eLife. 9, e53381.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Sulfation Modulates the Targeting Properties of Hyaluronic Acid to P-Selectin and CD44

Bhattacharya, D. S., Svechkarev, D., Bapat, A., Patil, P., Hollingsworth, M. A. & Mohs, A. M., Jun 8 2020, In : ACS Biomaterials Science and Engineering. 6, 6, p. 3585-3598 14 p.

Research output: Contribution to journalArticle

The proteomic landscape of pancreatic ductal adenocarcinoma liver metastases identifies molecular subtypes and associations with clinical response A C

Law, H. C. H., Lagundzin, D., Clement, E. J., Qiao, F., Wagner, Z. S., Krieger, K. L., Costanzo-Garvey, D., Caffrey, T. C., Grem, J. L., DiMaio, D. J., Grandgenett, P. M., Cook, L. M., Fisher, K. W., Yu, F., Hollingsworth, M. A. & Woods, N. T., Mar 1 2020, In : Clinical Cancer Research. 26, 5, p. 1065-1076 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Tuned near infrared fluorescent hyaluronic acid conjugates for delivery to pancreatic cancer for intraoperative imaging

Qi, B., Crawford, A. J., Wojtynek, N. E., Talmon, G. A., Hollingsworth, M. A., Ly, Q. P. & Mohs, A. M., 2020, In : Theranostics. 10, 8, p. 3413-3429 17 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Upregulation of ZIP14 and altered zinc homeostasis in muscles in pancreatic cancer cachexia

Shakri, A. R., Zhong, T. J., Ma, W., Coker, C., Kim, S., Calluori, S., Scholze, H., Szabolcs, M., Caffrey, T., Grandgenett, P. M., Hollingsworth, M. A., Tanji, K., Kluger, M. D., Miller, G., Biswas, A. K. & Acharyya, S., Jan 2020, In : Cancers. 12, 1, 3.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2019

A polymeric nanogel-based treatment regimen for enhanced efficacy and sequential administration of synergistic drug combination in pancreatic cancer

Soni, K. S., Thomas, D., Caffrey, T., Mehla, K., Lei, F., O'Connell, K. A., Sagar, S., Lele, S. M., Hollingsworth, M. A., Radhakrishnan, P. & Bronich, T. K., 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 3, p. 894-901 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

CDK5 inhibitor downregulates Mcl-1 and sensitizes pancreatic cancer cell lines to navitoclax

Kour, S., Rana, S., Contreras, J. I., King, H. M., Robb, C. M., Sonawane, Y. A., Bendjennat, M., Crawford, A. J., Barger, C. J., Kizhake, S., Luo, X., Hollingsworth, M. A. & Natarajan, A., Oct 2019, In : Molecular pharmacology. 96, 4, p. 419-429 11 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Inhibition of geranylgeranyl diphosphate synthase is a novel therapeutic strategy for pancreatic ductal adenocarcinoma

Haney, S. L., Varney, M. L., Chhonker, Y. S., Shin, S., Mehla, K., Crawford, A. J., Smith, H. J., Smith, L. M., Murry, D. J., Hollingsworth, M. A. & Holstein, S. A., Jun 27 2019, In : Oncogene. 38, 26, p. 5308-5320 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases

Connor, A. A., Denroche, R. E., Jang, G. H., Lemire, M., Zhang, A., Chan-Seng-Yue, M., Wilson, G., Grant, R. C., Merico, D., Lungu, I., Bartlett, J. M. S., Chadwick, D., Liang, S. B., Eagles, J., Mbabaali, F., Miller, J. K., Krzyzanowski, P., Armstrong, H., Luo, X., Jorgensen, L. G. T. & 25 others, Romero, J. M., Bavi, P., Fischer, S. E., Serra, S., Hafezi-Bakhtiari, S., Caglar, D., Roehrl, M. H. A., Cleary, S., Hollingsworth, M. A., Petersen, G. M., Thayer, S., Law, C. H. L., Nanji, S., Golan, T., Smith, A. L., Borgida, A., Dodd, A., Hedley, D., Wouters, B. G., O'Kane, G. M., Wilson, J. M., Zogopoulos, G., Notta, F., Knox, J. J. & Gallinger, S., Feb 11 2019, In : Cancer Cell. 35, 2, p. 267-282.e7

Research output: Contribution to journalArticle

17 Scopus citations

Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis

Liu, X., Clemens, D. L., Grunkemeyer, J. A., Price, J. D., O’Connell, K., Chapman, N. M., Storz, P., Wen, H., Cox, J. L., Reid, W. L., Hollingsworth, M. A. & Thayer, S., Dec 1 2019, In : Scientific reports. 9, 1, 10656.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Shi, Y., Gao, W., Lytle, N. K., Huang, P., Yuan, X., Dann, A. M., Ridinger-Saison, M., DelGiorno, K. E., Antal, C. E., Liang, G., Atkins, A. R., Erikson, G., Sun, H., Meisenhelder, J., Terenziani, E., Woo, G., Fang, L., Santisakultarm, T. P., Manor, U., Xu, R. & 18 others, Becerra, C. R., Borazanci, E., Von Hoff, D. D., Grandgenett, P. M., Hollingsworth, M. A., Leblanc, M., Umetsu, S. E., Collisson, E. A., Scadeng, M., Lowy, A. M., Donahue, T. R., Reya, T., Downes, M., Evans, R. M., Wahl, G. M., Pawson, T., Tian, R. & Hunter, T., May 2 2019, In : Nature. 569, 7754, p. 131-135 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice

Engle, D. D., Tiriac, H., Rivera, K. D., Pommier, A., Whalen, S., Oni, T. E., Alagesan, B., Lee, E. J., Yao, M. A., Lucito, M. S., Spielman, B., Silva, B. D., Schoepfer, C., Wright, K., Creighton, B., Afinowicz, L., Yu, K. H., Grützmann, R., Aust, D., Gimotty, P. A. & 8 others, Pollard, K. S., Hruban, R. H., Goggins, M. G., Pilarsky, C., Park, Y., Pappin, D. J., Hollingsworth, M. A. & Tuveson, D. A., 2019, In : Science. 364, 6446, p. 1156-1162 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

The glycoprotein mucin-1 negatively regulates GalNAc transferase 5 expression in pancreatic cancer

Caffrey, T., Sagar, S., Thomas, D., Lewallen, M. E., Hollingsworth, M. A. & Radhakrishnan, P., Oct 1 2019, In : FEBS Letters. 593, 19, p. 2751-2761 11 p.

Research output: Contribution to journalArticle

2018

Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy

Robb, C. M., Kour, S., Contreras, J. I., Agarwal, E., Barger, C. J., Rana, S., Sonawane, Y., Neilsen, B. K., Taylor, M., Kizhake, S., Thakare, R. N., Chowdhury, S., Wang, J., Black, J. D., Hollingsworth, M. A., Brattain, M. G. & Natarajan, A., 2018, In : Oncotarget. 9, 4, p. 5216-5232 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy

Contreras, J. I., Robb, C. M., King, H. M., Baxter, J., Crawford, A. J., Kour, S., Kizhake, S., Sonawane, Y. A., Rana, S., Hollingsworth, M. A., Luo, X. & Natarajan, A., May 18 2018, In : ACS chemical biology. 13, 5, p. 1148-1152 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Combination of mAb-AR20.5, anti-PD-L1 and PolyICLC inhibits tumor progression and prolongs survival of MUC1.Tg mice challenged with pancreatic tumors

Mehla, K., Tremayne, J., Grunkemeyer, J. A., O’Connell, K. A., Steele, M. M., Caffrey, T. C., Zhu, X., Yu, F., Singh, P. K., Schultes, B. C., Madiyalakan, R., Nicodemus, C. F. & Hollingsworth, M. A., Mar 1 2018, In : Cancer Immunology, Immunotherapy. 67, 3, p. 445-457 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Indocyanine green loaded hyaluronan-derived nanoparticles for fluorescence-enhanced surgical imaging of pancreatic cancer

Qi, B., Crawford, A. J., Wojtynek, N. E., Holmes, M. B., Souchek, J. J., Almeida-Porada, G., Ly, Q. P., Cohen, S. M., Hollingsworth, M. A. & Mohs, A. M., Apr 2018, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 3, p. 769-780 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Macrophage-derived neuropilin-2 exhibits novel tumor-promoting functions

Roy, S., Bag, A. K., Dutta, S., Polavaram, N. S., Islam, R., Schellenburg, S., Banwait, J., Guda, C., Ran, S., Hollingsworth, M. A., Singh, R. K., Talmadge, J. E., Muders, M. H., Batra, S. K. & Datta, K., Oct 1 2018, In : Cancer Research. 78, 19, p. 5600-5617 18 p.

Research output: Contribution to journalArticle

10 Scopus citations

Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle

Wang, G., Biswas, A. K., Ma, W., Kandpal, M., Coker, C., Grandgenett, P. M., Hollingsworth, M. A., Jain, R., Tanji, K., López-Pintado, S., Borczuk, A., Hebert, D., Jenkitkasemwong, S., Hojyo, S., Davuluri, R. V., Knutson, M. D., Fukada, T. & Acharyya, S., Jun 1 2018, In : Nature Medicine. 24, 6, p. 770-781 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Met receptor inhibitor SU11274 localizes in the endoplasmic reticulum

Wiest, E. J., Smith, H. J. & Hollingsworth, M. A., Jul 2 2018, In : Biochemical and Biophysical Research Communications. 501, 4, p. 858-862 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschênes, A., Somerville, T. D. D., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., Lacomb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. C., Johnson, M., Arora, K. & 50 others, Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., Dimaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O’kane, G. M., Notta, F., Kim, E., Crawford, J. M., Devoe, C., Ocean, A., Wolfgang, C. L., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R., Knox, J., Krasnitz, A., Gallinger, S. & Tuveson, D. A., Sep 2018, In : Cancer Discovery. 8, 9, p. 1112-1129 18 p.

Research output: Contribution to journalArticle

126 Scopus citations
2017

A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study

Kaur, S., Smith, L. M., Patel, A., Menning, M., Watley, D. C., Malik, S. S., Krishn, S. R., Mallya, K., Aithal, A., Sasson, A. R., Johansson, S. L., Jain, M., Singh, S., Guha, S., Are, C., Raimondo, M., Hollingsworth, M. A., Brand, R. E. & Batra, S. K., Jan 1 2017, In : American Journal of Gastroenterology. 112, 1, p. 172-183 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Association of distinct mutational signatures with correlates of increased immune activity in pancreatic ductal adenocarcinoma

Connor, A. A., Denroche, R. E., Jang, G. H., Timms, L., Kalimuthu, S. N., Selander, I., McPherson, T., Wilson, G. W., Chan-Seng-Yue, M. A., Borozan, I., Ferretti, V., Grant, R. C., Lungu, I. M., Costello, E., Greenhalf, W., Palmer, D., Ghaneh, P., Neoptolemos, J. P., Buchler, M., Petersen, G. & 20 others, Thayer, S., Hollingsworth, M. A., Sherker, A., Durocher, D., Dhani, N., Hedley, D., Serra, S., Pollett, A., Roehrl, M. H. A., Bavi, P., Bartlett, J. M. S., Cleary, S., Wilson, J. M., Alexandrov, L. B., Moore, M., Wouters, B. G., McPherson, J. D., Notta, F., Stein, L. D. & Gallinger, S., Jun 2017, In : JAMA Oncology. 3, 6, p. 774-783 10 p.

Research output: Contribution to journalArticle

90 Scopus citations

Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis

Roe, J. S., Hwang, C. I., Somerville, T. D. D., Milazzo, J. P., Lee, E. J., Da Silva, B., Maiorino, L., Tiriac, H., Young, C. M., Miyabayashi, K., Filippini, D., Creighton, B., Burkhart, R. A., Buscaglia, J. M., Kim, E. J., Grem, J. L., Lazenby, A. J., Grunkemeyer, J. A., Hollingsworth, M. A., Grandgenett, P. M. & 4 others, Egeblad, M., Park, Y., Tuveson, D. A. & Vakoc, C. R., Aug 24 2017, In : Cell. 170, 5, p. 875-888.e20

Research output: Contribution to journalArticle

103 Scopus citations

MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer

Shukla, S. K., Purohit, V., Mehla, K., Gunda, V., Chaika, N. V., Vernucci, E., King, R. J., Abrego, J., Goode, G. D., Dasgupta, A., Illies, A. L., Gebregiworgis, T., Dai, B., Augustine, J. J., Murthy, D., Attri, K. S., Mashadova, O., Grandgenett, P. M., Powers, R., Ly, Q. P. & 17 others, Lazenby, A. J., Grem, J. L., Yu, F., Matés, J. M., Asara, J. M., Kim, J. W., Hankins, J. H., Weekes, C., Hollingsworth, M. A., Serkova, N. J., Sasson, A. R., Fleming, J. B., Oliveto, J. M., Lyssiotis, C. A., Cantley, L. C., Berim, L. & Singh, P. K., Jul 10 2017, In : Cancer Cell. 32, 1, p. 71-87.e7

Research output: Contribution to journalArticle

109 Scopus citations

Stromal content is correlated with tissue site, contrast retention, and survival in pancreatic adenocarcinoma

Torphy, R. J., Wang, Z., True-Yasaki, A., Volmar, K. E., Rashid, N., Yeh, B., Johansen, J. S., Hollingsworth, M. A., Yeh, J. J. & Collisson, E. A., 2017, In : JCO Precision Oncology. 1

Research output: Contribution to journalArticle

2 Scopus citations

TET1-mediated DNA hypomethylation regulates the expression of MUC4 in lung cancer

Yokoyama, S., Higashi, M., Tsutsumida, H., Wakimoto, J., Hamada, T., Wiest, E., Matsuo, K., Kitazono, I., Goto, Y., Guo, X., Hamada, T., Yamada, S., Hiraki, T., Yonezawa, S., Batra, S. K., Hollingsworth, M. A. & Tanimoto, A., Mar 2017, In : Genes and Cancer. 8, 3-4, p. 517-527 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas

Yokoyama, S., Higashi, M., Kitamoto, S., Oeldorf, M., Knippschild, U., Kornmann, M., Maemura, K., Kurahara, H., Wiest, E., Hamada, T., Kitazono, I., Goto, Y., Tasaki, T., Hiraki, T., Hatanaka, K., Mataki, Y., Taguchi, H., Hashimoto, S., Batra, S. K., Tanimoto, A. & 2 others, Yonezawa, S. & Hollingsworth, M. A., Jul 5 2016, In : Oncotarget. 7, 27, p. 42553-42565 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

Notta, F., Chan-Seng-Yue, M., Lemire, M., Li, Y., Wilson, G. W., Connor, A. A., Denroche, R. E., Liang, S. B., Brown, A. M. K., Kim, J. C., Wang, T., Simpson, J. T., Beck, T., Borgida, A., Buchner, N., Chadwick, D., Hafezi-Bakhtiari, S., Dick, J. E., Heisler, L., Hollingsworth, M. A. & 26 others, Ibrahimov, E., Jang, G. H., Johns, J., Jorgensen, L. G. T., Law, C., Ludkovski, O., Lungu, I., Ng, K., Pasternack, D., Petersen, G. M., Shlush, L. I., Timms, L., Tsao, M. S., Wilson, J. M., Yung, C. K., Zogopoulos, G., Bartlett, J. M. S., Alexandrov, L. B., Real, F. X., Cleary, S. P., Roehrl, M. H., McPherson, J. D., Stein, L. D., Hudson, T. J., Campbell, P. J. & Gallinger, S., 2016, In : Nature. 538, 7625, p. 378-382 5 p.

Research output: Contribution to journalArticle

191 Scopus citations

Effect of MUC1/β-catenin interaction on the tumorigenic capacity of pancreatic CD133+ cells

Sousa, A. M., Rei, M., Freitas, R., Ricardo, S., Caffrey, T., David, L., Almeida, R., Hollingsworth, M. A. & Santos-Silva, F., Sep 2016, In : Oncology Letters. 12, 3, p. 1811-1817 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Identification of FRA-1 as a novel player in pancreatic cancer in cooperation with a MUC1: ERK signaling axis

Hanson, R. L., Brown, R. B., Steele, M. M., Grandgenett, P. M., Grunkemeyer, J. A. & Hollingsworth, M. A., 2016, In : Oncotarget. 7, 26, p. 39996-40011 16 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma

Fox, R. G., Lytle, N. K., Jaquish, D. V., Park, F. D., Ito, T., Bajaj, J., Koechlein, C. S., Zimdahl, B., Yano, M., Kopp, J. L., Kritzik, M., Sicklick, J. K., Sander, M., Grandgenett, P. M., Hollingsworth, M. A., Shibata, S., Pizzo, D., Valasek, M. A., Sasik, R., Scadeng, M. & 5 others, Okano, H., Kim, Y., Macleod, A. R., Lowy, A. M. & Reya, T., Jun 6 2016, In : Nature. 534, 7607, p. 407-411 5 p.

Research output: Contribution to journalArticle

57 Scopus citations

Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer

Krishn, S. R., Kaur, S., Smith, L. M., Johansson, S. L., Jain, M., Patel, A., Gautam, S. K., Hollingsworth, M. A., Mandel, U., Clausen, H., Lo, W. C., Fan, W. T. L., Manne, U. & Batra, S. K., May 1 2016, In : Cancer Letters. 374, 2, p. 304-314 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Oncofetal chondroitin sulfate glycosaminoglycans are key players in integrin signaling and tumor cell motility

Clausen, T. M., Pereira, M. A., Nakouzi, N. A., Oo, H. Z., Agerbæk, M., Lee, S., Ørum-Madsen, M. S., Kristensen, A. R., El-Naggar, A., Grandgenett, P. M., Grem, J. L., Hollingsworth, M. A., Holst, P. J., Theander, T., Sorensen, P. H., Daugaard, M. & Salanti, A., Dec 1 2016, In : Molecular Cancer Research. 14, 12, p. 1288-1299 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Proteomic mapping of p53 immunogenicity in pancreatic, ovarian, and breast cancers

Katchman, B. A., Barderas, R., Alam, R., Chowell, D., Field, M. S., Esserman, L. J., Wallstrom, G., LaBaer, J., Cramer, D. W., Hollingsworth, M. A. & Anderson, K. S., Jul 1 2016, In : Proteomics - Clinical Applications. 10, 7, p. 720-731 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells

Wuebben, E. L., Wilder, P. J., Cox, J. L., Grunkemeyer, J. A., Caffrey, T., Hollingsworth, M. A. & Rizzino, A., Jun 7 2016, In : Oncotarget. 7, 23, p. 34890-34906 17 p.

Research output: Contribution to journalArticle

12 Scopus citations

The small heat shock protein βA-crystallin negatively regulates pancreatic tumorigenesis

Liu, J., Luo, Z., Zhang, L., Wang, L., Nie, Q., Wang, Z. F., Huang, Z., Hu, X., Gong, L., Arrigo, A. P., Tang, X., Xiang, J. W., Liu, F., Deng, M., Ji, W., Hu, W., Zhu, J. Y., Chen, B., Bridge, J., Hollingsworth, M. A. & 4 others, Gigantelli, J. W., Liu, Y., Nguyen, Q. D. & Li, D. W. C., 2016, In : Oncotarget. 7, 40, p. 65808-65824 17 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015
10 Scopus citations

Amyloid precursor-like protein 2 (APLP2) affects the actin cytoskeleton and increases pancreatic cancer growth and metastasis

Pandey, P., Rachagani, S., Das, S., Seshacharyulu, P., Sheinin, Y., Naslavsky, N., Pan, Z., Smith, B. L., Peters, H. L., Radhakrishnan, P., McKenna, N. R., Panapakkam Giridharan, S. S., Haridas, D., Kaur, S., Hollingsworth, M. A., MacDonald, R. G., Meza, J. L., Caplan, S., Batra, S. K. & Solheim, J. C., 2015, In : Oncotarget. 6, 4, p. 2064-2075 12 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs

Londina, E., Lohera, P., Telonis, A. G., Quann, K., Clark, P., Jinga, Y., Hatzimichael, E., Kirino, Y., Honda, S., Lally, M., Ramratnam, B., Comstock, C. E. S., Knudsen, K. E., Gomella, L., Spaeth, G. L., Hark, L., Katz, L. J., Witkiewicz, A., Rostami, A., Jimenez, S. A. & 18 others, Hollingsworth, M. A., Yeh, J. J., Shaw, C. A., McKenzie, S. E., Bray, P., Nelson, P. T., Zupo, S., Van Roosbroeck, K., Keating, M. J., Calin, G. A., Yeo, C., Jimbo, M., Cozzitorto, J., Brody, J. R., Delgrosso, K., Mattick, J. S., Fortina, P. & Rigoutsos, I., Mar 10 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 10, p. E1106-E1115

Research output: Contribution to journalArticle

241 Scopus citations

Definitive characterization of CA 19-9 in resectable pancreatic cancer using a reference set of serum and plasma specimens

Haab, B. B., Huang, Y., Balasenthil, S., Partyka, K., Tang, H., Anderson, M., Allen, P., Sasson, A., Zeh, H., Kaul, K., Kletter, D., Ge, S., Bern, M., Kwon, R., Blasutig, I., Srivastava, S., Frazier, M. L., Sen, S., Hollingsworth, M. A., Rinaudo, J. A. & 2 others, Killary, A. M. & Brand, R. E., Oct 2 2015, In : PloS one. 10, 10, e0139049.

Research output: Contribution to journalArticle

14 Scopus citations