Wallace B Thoreson, PhD

  • 4208 Citations
  • 38 h-Index
1986 …2020

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2020

Simultaneous Release of Multiple Vesicles from Rods Involves Synaptic Ribbons and Syntaxin 3B

Hays, C. L., Grassmeyer, J. J., Wen, X., Janz, R., Heidelberger, R. & Thoreson, W. B., Feb 25 2020, In : Biophysical journal. 118, 4, p. 967-979 13 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Ca2+ sensor synaptotagmin-1 mediates exocytosis in mammalian photoreceptors

Grassmeyer, J. J., Cahill, A. L., Hays, C. L., Barta, C., Quadros, R. M., Gurumurthy, C. B. & Thoreson, W. B., Jun 2019, In : eLife. 8, e45946.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Diverse cell types, circuits, and mechanisms for color vision in the vertebrate retina

Thoreson, W. B. & Dacey, D. M., Jul 2019, In : Physiological Reviews. 99, 3, p. 1527-1573 47 p.

Research output: Contribution to journalArticle

6 Scopus citations
2018

Elevated pressure increases Ca2+ influx through AMPA receptors in select populations of retinal ganglion cells

Wen, X., Cahill, A. L., Barta, C., Thoreson, W. B. & Nawy, S. A., Jun 13 2018, In : Frontiers in Cellular Neuroscience. 12, 162.

Research output: Contribution to journalArticle

1 Scopus citations

Endocytosis sustains release at photoreceptor ribbon synapses by restoring fusion competence

Wen, X., Van Hook, M. J., Grassmeyer, J. J., Wiesman, A. I., Rich, G. M., Cork, K. M. & Thoreson, W. B., Apr 1 2018, In : Journal of General Physiology. 150, 4, p. 591-611 21 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

A presynaptic group III mGluR recruits Gβγ/SNARE interactions to inhibit synaptic transmission by cone photoreceptors in the vertebrate retina

Van Hook, M. J., Babai, N., Zurawski, Z., Yim, Y. Y., Hamm, H. E. & Thoreson, W. B., Apr 26 2017, In : Journal of Neuroscience. 37, 17, p. 4618-4634 17 p.

Research output: Contribution to journalArticle

7 Scopus citations

Easi-CRISPR: A robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins

Quadros, R. M., Miura, H., Harms, D. W., Akatsuka, H., Sato, T., Aida, T., Redder, R., Richardson, G. P., Inagaki, Y., Sakai, D., Buckley, S. M., Seshacharyulu, P., Batra, S. K., Behlke, M. A., Zeiner, S. A., Jacobi, A. M., Izu, Y., Thoreson, W. B., Urness, L. D., Mansour, S. L. & 2 others, Ohtsuka, M. & Gurumurthy, C. B., May 17 2017, In : Genome biology. 18, 1, 92.

Research output: Contribution to journalArticle

99 Scopus citations

Kiss-and-run is a significant contributor to synaptic exocytosis and endocytosis in photoreceptors

Wen, X., Saltzgaber, G. W. & Thoreson, W. B., Sep 20 2017, In : Frontiers in Cellular Neuroscience. 11, 286.

Research output: Contribution to journalArticle

6 Scopus citations

Synaptic ribbon active zones in cone photoreceptors operate independently from one another

Grassmeyer, J. J. & Thoreson, W. B., Jul 11 2017, In : Frontiers in Cellular Neuroscience. 11, 198.

Research output: Contribution to journalArticle

7 Scopus citations

Two Pools of Vesicles Associated with Synaptic Ribbons Are Molecularly Prepared for Release

Datta, P., Gilliam, J., Thoreson, W. B., Janz, R. & Heidelberger, R., Nov 21 2017, In : Biophysical journal. 113, 10, p. 2281-2298 18 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Kinetics of inhibitory feedback from horizontal cells to photoreceptors: Implications for an ephaptic mechanism

Warren, T. J., Van Hook, M. J., Tranchina, D. & Thoreson, W. B., Sep 28 2016, In : Journal of Neuroscience. 36, 39, p. 10075-10088 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Mechanisms, pools, and sites of spontaneous vesicle release at synapses of rod and cone photoreceptors

Cork, K. M., Van Hook, M. J. & Thoreson, W. B., Aug 1 2016, In : European Journal of Neuroscience. 44, 3, p. 2015-2027 13 p.

Research output: Contribution to journalArticle

10 Scopus citations
9 Scopus citations

Retinal Dystrophy and Optic Nerve Pathology in the Mouse Model of Mucolipidosis IV

Grishchuk, Y., Stember, K. G., Matsunaga, A., Olivares, A. M., Cruz, N. M., King, V. E., Humphrey, D. M., Wang, S. L., Muzikansky, A., Betensky, R. A., Thoreson, W. B., Haider, N. & Slaugenhaupt, S. A., Jan 1 2016, In : American Journal of Pathology. 186, 1, p. 199-209 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Sources of protons and a role for bicarbonate in inhibitory feedback from horizontal cells to cones in Ambystoma tigrinum retina

Warren, T. J., Van Hook, M. J., Supuran, C. T. & Thoreson, W. B., Nov 15 2016, In : Journal of Physiology. 594, 22, p. 6661-6677 17 p.

Research output: Contribution to journalArticle

18 Scopus citations
2015
10 Scopus citations

Direct differentiation of adult ocular progenitors into striatal dopaminergic neurons

Ahmad, I., Zhao, X., Parameswaran, S., Destache, C. J., Rodriguez-Sierra, J., Thoreson, W. B., Ahmad, H., Sorrentino, J. & Balasubramanian, S., Jan 1 2015, In : International Journal of Stem Cells. 8, 1, p. 106-114 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Naturally occurring deletion mutants of the Pig-Specific, Intestinal crypt epithelial cell protein CLCA4b without Apparent Phenotype

Plog, S., Klymiuk, N., Binder, S., Van Hook, M. J., Thoreson, W. B., Gruber, A. D. & Mundhenk, L., Oct 16 2015, In : PloS one. 10, 10, e0140050.

Research output: Contribution to journalArticle

4 Scopus citations
11 Scopus citations
2014

Calmodulin enhances ribbon replenishment and shapes filtering of synaptic transmission by cone photoreceptors

van Hook, M. J., Parmelee, C. M., Chen, M., Cork, K. M., Curto, C. & Thoreson, W. B., Jan 1 2014, In : Journal of General Physiology. 144, 5, p. 357-378 22 p.

Research output: Contribution to journalArticle

15 Scopus citations

Endogenous calcium buffering at photoreceptor synaptic terminals in salamander retina

Van Hook, M. J. & Thoreson, W. B., Nov 1 2014, In : Synapse. 68, 11, p. 518-528 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Examination of VLC-PUFA-deficient photoreceptor terminals

Bennett, L. D., Hopiavuori, B. R., Brush, R. S., Chan, M., Van Hook, M. J., Thoreson, W. B. & Anderson, R. E., Apr 24 2014, In : Investigative Ophthalmology and Visual Science. 55, 7, p. 4063-4072 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Intracellular calcium stores drive slow non-ribbon vesicle release from rod photoreceptors

Chen, M., Križaj, D. & Thoreson, W. B., Feb 3 2014, In : Frontiers in Cellular Neuroscience. 8, FEB, 20.

Research output: Contribution to journalArticle

18 Scopus citations

Rapid kinetics of endocytosis at rod photoreceptor synapses depends upon endocytic load and calcium

Cork, K. M. & Thoreson, W. B., May 2014, In : Visual Neuroscience. 31, 3, p. 227-235 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Simultaneous recording of mouse retinal ganglion cells during epiretinal or subretinal stimulation

Sim, S. L., Szalewski, R. J., Johnson, L. J., Akah, L. E., Shoemaker, L. E., Thoreson, W. B. & Margalit, E., Aug 2014, In : Vision research. 101, p. 41-50 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Swelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and glia

Ryskamp, D. A., Jo, A. O., Frye, A. M., Vazquez-Chona, F., MaCaulay, N., Thoreson, W. B. & Križaj, D., Nov 19 2014, In : Journal of Neuroscience. 34, 47, p. 15689-15700 12 p.

Research output: Contribution to journalArticle

42 Scopus citations
2013

Lateral mobility of L-type calcium channels in synaptic terminals of retinal bipolar cells

Thoreson, W. B., Mercer, A. J., Cork, K. M. & Szalewski, R. J., Jan 7 2013, In : Molecular Vision. 19, p. 16-24 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
8 Scopus citations

Properties of ribbon and non-ribbon release from rod photoreceptors revealed by visualizing individual synaptic vesicles

Chen, M., Van Hook, M. J., Zenisek, D. & Thoreson, W. B., Jan 30 2013, In : Journal of Neuroscience. 33, 5, p. 2071-2086 16 p.

Research output: Contribution to journalArticle

35 Scopus citations
25 Scopus citations
2 Scopus citations
2012

A comparison of optical and electrophysiological methods for recording retinal ganglion cells during electrical stimulation

Luo, J., Boosalis, B. J., Thoreson, W. B. & Margalit, E., Mar 1 2012, In : Current Eye Research. 37, 3, p. 218-227 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

CXCL12 enhances human neural progenitor cell survival through a CXCR7- and CXCR4-mediated endocytotic signaling pathway

Zhu, B., Xu, D., Deng, X., Chen, Q., Huang, Y., Peng, H., Li, Y., Jia, B., Thoreson, W. B., Ding, W., Ding, J., Zhao, L., Wang, Y., Wavrin, K. L., Duan, S. & Zheng, J., Nov 1 2012, In : STEM CELLS. 30, 11, p. 2571-2583 13 p.

Research output: Contribution to journalArticle

60 Scopus citations

Rapid synaptic vesicle endocytosis in cone photoreceptors of salamander retina

Van Hook, M. J. & Thoreson, W. B., Dec 12 2012, In : Journal of Neuroscience. 32, 50, p. 18112-18123 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Regulation of presynaptic strength by controlling Ca 2+ channel mobility: Effects of cholesterol depletion on release at the cone ribbon synapse

Mercer, A. J., Szalewski, R. J., Jackman, S. L., Van Hook, M. J. & Thoreson, W. B., Jun 15 2012, In : Journal of Neurophysiology. 107, 12, p. 3468-3478 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
2011

Acute destruction of the synaptic ribbon reveals a role for the ribbon in vesicle priming

Snellman, J., Mehta, B., Babai, N., Bartoletti, T. M., Akmentin, W., Francis, A., Matthews, G., Thoreson, W. & Zenisek, D., Sep 1 2011, In : Nature Neuroscience. 14, 9, p. 1135-1143 9 p.

Research output: Contribution to journalArticle

86 Scopus citations

A positive feedback synapse from retinal horizontal cells to cone photoreceptors

Jackman, S. L., Babai, N., Chambers, J. J., Thoreson, W. B. & Kramer, R. H., May 1 2011, In : PLoS biology. 9, 5, e1001057.

Research output: Contribution to journalArticle

43 Scopus citations

Center/surround organization of retinal bipolar cells: High correlation of fundamental responses of center and surround to sinusoidal contrasts

Burkhardt, D. A., Bartoletti, T. M. & Thoreson, W. B., May 1 2011, In : Visual Neuroscience. 28, 3, p. 183-192 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Inner and outer retinal mechanisms engaged by epiretinal stimulation in normal and rd mice

Margalit, E., Babai, N., Luo, J. & Thoreson, W. B., Mar 1 2011, In : Visual Neuroscience. 28, 2, p. 145-154 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Intracellular pH modulates inner segment calcium homeostasis in vertebrate photoreceptors

Križaj, D., Mercer, A. J., Thoreson, W. B. & Barabas, P., Jan 1 2011, In : American Journal of Physiology - Cell Physiology. 300, 1, p. C187-C197

Research output: Contribution to journalArticle

11 Scopus citations

Lateral mobility of presynaptic L-Type calcium channels at photoreceptor ribbon synapses

Mercer, A. J., Chen, M. & Thoreson, W. B., Mar 23 2011, In : Journal of Neuroscience. 31, 12, p. 4397-4406 10 p.

Research output: Contribution to journalArticle

52 Scopus citations

Location of release sites and calcium-activated chloride channels relative to calcium channels at the photoreceptor ribbon synapse

Mercer, A. J., Rabl, K., Riccardi, G. E., Brecha, N. C., Stella, S. L. & Thoreson, W. B., Jan 1 2011, In : Journal of Neurophysiology. 105, 1, p. 321-335 15 p.

Research output: Contribution to journalArticle

46 Scopus citations

Quantal amplitude at the cone ribbon synapse can be adjusted by changes in cytosolic glutamate

Bartoletti, T. M. & Thoreson, W. B., May 9 2011, In : Molecular Vision. 17, p. 920-931 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Release from the cone ribbon synapse under bright light conditions can be controlled by the opening of only a few Ca 2+ channels

Bartoletti, T. M., Jackman, S. L., Babai, N., Mercer, A. J., Kramer, R. H. & Thoreson, W. B., Dec 1 2011, In : Journal of Neurophysiology. 106, 6, p. 2922-2935 14 p.

Research output: Contribution to journalArticle

33 Scopus citations
2010

Anion-sensitive regions of L-type CaV1.2 calcium channels expressed in HEK293 cells

Babai, N., Kanevsky, N., Dascal, N., Rozanski, G. J., Singh, D. P., Fatma, N. & Thoreson, W. B., Jan 6 2010, In : PloS one. 5, 1, e8602.

Research output: Contribution to journalArticle

15 Scopus citations

Calcium-induced calcium release contributes to synaptic release from mouse rod photoreceptors

Babai, N., Morgans, C. W. & Thoreson, W. B., Feb 17 2010, In : Neuroscience. 165, 4, p. 1447-1456 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Calcium regulates vesicle replenishment at the cone ribbon synapse

Babai, N., Bartoletti, T. M. & Thoreson, W. B., Nov 24 2010, In : Journal of Neuroscience. 30, 47, p. 15866-15877 12 p.

Research output: Contribution to journalArticle

37 Scopus citations

Flow of energy in the outer retina in darkness and in light

Linton, J. D., Holzhausen, L. C., Babai, N., Song, H., Miyagishima, K. J., Stearns, G. W., Lindsay, K., Wei, J., Chertov, A. O., Peters, T. A., Caffe, R., Pluk, H., Seeliger, M. W., Tanimoto, N., Fong, K., Bolton, L., Kuok, D. L. T., Sweet, I. R., Bartoletti, T. M., Radu, R. A. & 9 others, Travis, G. H., Zagotta, W. N., Townes-Anderson, E., Parker, E., Van Der Zee, C. E. E. M., Sampath, A. P., Sokolov, M., Thoreson, W. B. & Hurley, J. B., May 11 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 19, p. 8599-8604 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Induced pluripotent stem cells generate both retinal ganglion cells and photoreceptors: Therapeutic implications in degenerative changes in glaucoma and age-related macular degeneration

Parameswaran, S., Balasubramanian, S., Babai, N., Qiu, F., Eudy, J. D., Thoreson, W. B. & Ahmad, I., Apr 1 2010, In : STEM CELLS. 28, 4, p. 695-703 9 p.

Research output: Contribution to journalArticle

91 Scopus citations