William H Velander, PhD, MChE

  • 1696 Citations
  • 24 h-Index
1987 …2020

Research output per year

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Research Output

2020

Novel fibrin-fibronectin matrix accelerates mice skin wound healing

Jara, C. P., Wang, O., Paulino do Prado, T., Ismail, A., Fabian, F. M., Li, H., Velloso, L. A., Carlson, M. A., Burgess, W., Lei, Y., Velander, W. H. & Araújo, E. P., Dec 2020, In : Bioactive Materials. 5, 4, p. 949-962 14 p.

Research output: Contribution to journalArticle

Open Access
Open Access
1 Scopus citations
2019

Co-expressing Turnip Crinkle Virus-coat protein with the serine protease α-thrombin precursor (pFIIa) in Nicotiana benthamiana Domin

Laguia-Becher, M., Zaldúa, Z., Xu, W., Marconi, P. L., Velander, W. & Alvarez, M. A., Feb 15 2019, In : In Vitro Cellular and Developmental Biology - Plant. 55, 1, p. 88-98 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

A totally recombinant fibrin matrix for mesenchymal stem cell culture and delivery

Wang, O., Ismail, A., Fabian, F. M., Lin, H., Li, Q., Elowsky, C., Carlson, M. A., Burgess, W., Velander, W. H., Kidambi, S. & Lei, Y., Dec 2018, In : Journal of Biomedical Materials Research - Part A. 106, 12, p. 3135-3142 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Fluid administration rate for uncontrolled intraabdominal hemorrhage in swine

Yanala, U. R., Johanning, J. M., Pipinos, I. I., High, R. R., Larsen, G., Velander, W. H. & Carlson, M. A., Nov 2018, In : PloS one. 13, 11, e0207708.

Research output: Contribution to journalArticle

The isolation of a plasma-derived γγ’ fibrinogen: Fibronectin mixture that forms a novel polymeric matrix

Ismail, A. E. A., Fabian, F. M., Wang, O., Lei, Y., Carlson, M. A., Burgess, W. H. & Velander, W. H., Dec 2018, In : Process Biochemistry. 75, p. 257-265 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Engineering protein processing of the mammary gland to produce abundant hemophilia B therapy in milk

Zhao, J., Xu, W., Ross, J. W., Walters, E. M., Butler, S. P., Whyte, J. J., Kelso, L., Fatemi, M., Vanderslice, N. C., Giroux, K., Spate, L. D., Samuel, M. S., Murphy, C. N., Wells, K. D., Masiello, N. C., Prather, R. S. & Velander, W. H., Sep 21 2015, In : Scientific reports. 5, 14176.

Research output: Contribution to journalArticle

7 Scopus citations

Quantifying vitamin K-dependent holoprotein compaction caused by differential γ-carboxylation using high-pressure size exclusion chromatography

Vanderslice, N. C., Messer, A. S., Vadivel, K., Bajaj, S. P., Phillips, M., Fatemi, M., Xu, W. & Velander, W. H., Jun 15 2015, In : Analytical Biochemistry. 479, p. 6-14 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

A totally recombinant human fibrin sealant

Carlson, M. A., Calcaterra, J., Johanning, J. M., Pipinos, I. I., Cordes, C. M. & Velander, W. H., Mar 2014, In : Journal of Surgical Research. 187, 1, p. 334-342 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
3 Scopus citations
2013

Coagulation Factor IXa

Monahan, P. E., Velander, W. H. & Paul Bajaj, S., 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, Vol. 3. p. 2898-2905 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Recombinant human fibrinogen that produces thick fibrin fibers with increased wound adhesion and clot density

Calcaterra, J., Van Cott, K. E., Butler, S. P., Gil, G. C., Germano, M., Van Veen, H. A., Nelson, K., Forsberg, E. J., Carlson, M. A. & Velander, W. H., Jan 14 2013, In : Biomacromolecules. 14, 1, p. 169-178 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
2011

Functional factor VIII made with von Willebrand factor at high levels in transgenic milk

Pipe, S. W., Miao, H., Butler, S. P., Calcaterra, J. & Velander, W. H., Nov 2011, In : Journal of Thrombosis and Haemostasis. 9, 11, p. 2235-2242 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2010
43 Scopus citations
2009
8 Scopus citations

N-glycosylation microheterogeneity and site occupancy of an Asn-X-Cys sequon in plasma-derived and recombinant protein C

Gil, G. C., Velander, W. H. & Van Cott, K. E., May 2009, In : Proteomics. 9, 9, p. 2555-2567 13 p.

Research output: Contribution to journalArticle

27 Scopus citations
2008

Analysis of the N-glycans of recombinant human Factor IX purified from transgenic pig milk

Gil, G. C., Velander, W. H. & Van Cott, K. E., Jul 2008, In : Glycobiology. 18, 7, p. 526-539 14 p.

Research output: Contribution to journalArticle

27 Scopus citations

Construction and characterization of a thrombin-resistant designer FGF-based collagen binding domain angiogen

Brewster, L. P., Washington, C., Brey, E. M., Gassman, A., Subramanian, A., Calceterra, J., Wolf, W., Hall, C. L., Velander, W. H., Burgess, W. H. & Greisler, H. P., Jan 2008, In : Biomaterials. 29, 3, p. 327-336 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
2006

Purificación del factor IX recombinante expresado en leche de cerdas transgénicas

Translated title of the contribution: Purification of recombinant factor IX expressed in milk of transgenic sowsLahens, A. C., Torres, A. M., Velander, W., Vidal, M. L., Sánchez, L. J., Rojas, A. R., Tito, L. S., Concepción, A. D., Almagro, P. C., González, D. C. & Vázquez, D. A., May 2006, In : Revista Cubana de Hematologia, Inmunologia y Hemoterapia. 22, 2

Research output: Contribution to journalArticle

1 Scopus citations
2005

Understanding endothelialization: Rate limitations in chemotaxis

Velander, W. H. & Washington, C., 2005. 1 p.

Research output: Contribution to conferencePaper

2004

Haemophilic factors produced by transgenic livestock: Abundance that can enable alternative therapies worldwide

Van Cott, K. E., Monahan, P. E., Nichols, T. C. & Velander, W. H., Oct 2004, In : Haemophilia, Supplement. 10, 4, p. 70-76 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Purification of recombinant DNA-derived factor IX produced in transgenic pig milk and fractionation of active and inactive subpopulations

Lindsay, M., Gil, G. C., Cadiz, A., Velander, W. H., Zhang, C. & Van Cott, K. E., Feb 13 2004, In : Journal of Chromatography A. 1026, 1-2, p. 149-157 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Secretion of recombinant human fibrinogen by the murine mammary gland

Butler, S., O'Sickey, T., Lord, S., Lubon, H., Gwazdauskas, F. & Velander, W., Oct 2004, In : Transgenic Research. 13, 5, p. 437-450 14 p.

Research output: Contribution to journalArticle

11 Scopus citations
2003

Development of murine embryos following electroporation

Schmotzer, C. A., Dunlap-Brown, M. E., Butler, S. P., Velander, W. H. & Gwazdauskas, F. C., Apr 1 2003, In : Journal of Assisted Reproduction and Genetics. 20, 4, p. 148-152 5 p.

Research output: Contribution to journalArticle

2002

Scale-up of microbubble dispersion generator for aerobic fermentation

Hensirisak, P., Parasukulsatid, P., Agblevor, F. A., Cundiff, J. S. & Velander, W. H., 2002, In : Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology. 101, 3, p. 211-227 17 p.

Research output: Contribution to journalArticle

23 Scopus citations
2001

Recombinant human protein C expression in the milk of transgenic pigs and the effect on endogenous milk immunoglobulin and transferrin levels

Cott, K. E. V., Lubon, H., Gwazdauskas, F. C., Knight, J., Drohan, W. N. & Velander, W. H., 2001, In : Transgenic Research. 10, 1, p. 43-51 9 p.

Research output: Contribution to journalArticle

30 Scopus citations
2000

Interferometric optical fiber microcantilever beam biosensor

Wavering, T., Meller, S., Evans, M., Pennington, C., Jones, M., Van Tassell, R., Murphy, K., Velander, W. & Valdes, E., 2000, In : Proceedings of SPIE - The International Society for Optical Engineering. 4200, p. 10-16 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Optical fiber extrinsic Fabry-Perot interferometric (EFPI)-based biosensors

Elster, J. L., Jones, M. E., Evans, M. K., Lenahan, S. M., Boyce, C. A., Velander, W. & Van Tassell, R., 2000, In : Proceedings of SPIE - The International Society for Optical Engineering. 3911, p. 105-112 8 p.

Research output: Contribution to journalConference article

20 Scopus citations

Ranking the factors impacting immunosorbent performance

Subramanian, A. & Velander, W. H., 2000, In : International Journal of Bio-Chromatography. 5, 1, p. 67-82 16 p.

Research output: Contribution to journalArticle

3 Scopus citations
1999

Bovine Follicular Dynamics, Oocyte Recovery, and Development of Oocytes Microinjected with a Green Fluorescent Protein Construct

Chauhan, M. S., Nadir, S., Bailey, T. L., Pryor, A. W., Butler, S. P., Notter, D. R., Velander, W. H. & Gwazdauskas, F. C., May 1999, In : Journal of Dairy Science. 82, 5, p. 918-926 9 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

In vitro embryo development of good and poor quality bovine oocytes following microinjection of DNA

Garst, A. S., Carlin, S. K., Glbbons, J. R., Kendrick, K. W., Pearson, R. E., Akers, R. M., Bailey, T. L., Velander, W. H., Lubon, H. K. & Gwazdauskas, F. C., 1999, In : Transgenics. 2, 4, p. 371-382 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Optical fiber-based chemical sensors for detection of corrosion precursors and by-products

Elster, J., Greene, J., Jones, M., Bailey, T., Lenahan, S., Velander, W., VanTassell, R., Hodges, W. & Perez, I., 1999, In : Proceedings of SPIE - The International Society for Optical Engineering. 3540, p. 251-257 7 p.

Research output: Contribution to journalConference article

10 Scopus citations

Transgenic pigs as bioreactors: A comparison of gamma-carboxylation of glutamic acid in recombinant human protein C and factor IX by the mammary gland

Van Cott, K. E., Butler, S. P., Russell, C. G., Subramanian, A., Lubon, H., Gwazdauskas, F. C., Knight, J., Drohan, W. N. & Velander, W. H., Nov 1999, In : Genetic Analysis - Biomolecular Engineering. 15, 3-5, p. 155-160 6 p.

Research output: Contribution to journalArticle

37 Scopus citations
1998
8 Scopus citations

Zn2+-selective purification of recombinant proteins from the milk of transgenic animals

Degener, A., Belew, M. & Velander, W. H., Mar 13 1998, In : Journal of Chromatography A. 799, 1-2, p. 125-137 13 p.

Research output: Contribution to journalArticle

17 Scopus citations
1997

Current progress in the production of recombinant human fibrinogen in the milk of transgenic animals

Butler, S. P., Van Cott, K., Subrumanian, A., Gwazduaskas, F. C. & Velander, W. H., Jul 1997, In : Thrombosis and Haemostasis. 78, 1, p. 537-542 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Dot-blot analysis of the degree of covalent modification of proteins and antibodies at amino groups

Morçöl, T., Subramanian, A. & Velander, W. H., Apr 11 1997, In : Journal of Immunological Methods. 203, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Expression of human fibrinogen in transgenic mice

Subramanian, A., Butler, S. P., Gwazdauskas, F. C., Lubon, H. & Velander, W. H., 1997, p. 57-60. 4 p.

Research output: Contribution to conferencePaper

1 Scopus citations

Phenotypic and genotypic stability of multiple lines of transgenic pigs expressing recombinant human protein C

Van Cott, K. E., Lubon, H., Russell, C. G., Butler, S. P., Gwazdauskas, F. C., Knight, J., Drohan, W. N. & Velander, W. H., 1997, In : Transgenic Research. 6, 3, p. 203-212 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Transgenic livestock as drug factories

Velander, W. H., Lubon, H. & Drohan, W. N., 1997, In : Scientific American. 276, 1, p. [d]70-74

Research output: Contribution to journalArticle

29 Scopus citations

Transgenic pigs produce functional human factor VIII in milk

Paleyanda, R. K., Velander, W. H., Lee, T. K., Scandella, D. H., Gwazdauskas, F. C., Knight, J. W., Hoyer, L. W., Drohan, W. N. & Lubon, H., Oct 1997, In : Nature Biotechnology. 15, 10, p. 971-975 5 p.

Research output: Contribution to journalArticle

101 Scopus citations
1996

Activation of recombinant human protein C

Lee, T. K., Bangalore, N., Velander, W., Drohan, W. N. & Lubon, H., May 1 1996, In : Thrombosis Research. 82, 3, p. 225-234 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Affinity Purification of Biologically Active and Inactive Forms of Recombinant Human Protein C Produced in Porcine Mammary Gland

Van Cott, K. E., Williams, B., Velander, W. H., Gwazdauskas, F., Lee, T., Lubon, H. & Drohan, W. N., 1996, In : Journal of Molecular Recognition. 9, 5-6, p. 407-414 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Effect of Antibody Orientation on Immunosorbent Performance

Subramanian, A. & Velander, W. H., 1996, In : Journal of Molecular Recognition. 9, 5-6, p. 528-535 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Human Plasma Proteins from Transgenic Animal Bioreactors

Paleyanda, R. K., Velander, W. H., Lee, T. K., Drews, R., Gwazdauskas, F. C., Knight, J. W., Drohan, W. N. & Lubon, H., 1996, In : ACS Symposium Series. 647, p. 205-217 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Proteins from transgenic animal bioreactors

Lubon, H., Paleyanda, R. K., Velander, W. H. & Drohan, W. N., 1996, In : Transfusion Medicine Reviews. 10, 2, p. 131-143 13 p.

Research output: Contribution to journalArticle

37 Scopus citations

Rate limitations in posttranslational processing by the mammary gland of transgenic animals

Subramanian, A., Paleyanda, R. K., Lubon, H., Williams, B. L., Gwazdauskas, F. C., Knight, J. W., Drohan, W. N. & Velander, W. H., 1996, In : Annals of the New York Academy of Sciences. 782, p. 87-96 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
1995

Transgene detection during early murine embryonic development after pronuclear microinjection

Page, R. L., Canseco, R. S., Russell, C. G., Johnson, J. L., Velander, W. H. & Gwazdauskas, F. C., Jan 1995, In : Transgenic Research. 4, 1, p. 12-17 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Transgenesis in mice by cytoplasmic injection of polylysine/DNA mixtures

Page, R. L., Butler, S. P., Subramanian, A., Gwazdauskas, F. C., Johnson, J. L. & Velander, W. H., Nov 1995, In : Transgenic Research. 4, 6, p. 353-360 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
1994

Development of bovine morulae after bisection and biopsy and assessment of DNA amplification by the polymerase chain reaction

Sparks, A. E. T., Canseco, R. S., Russell, C. G., Johnson, J. L., Page, J. L., Velander, W. H., McGilliard, M. L. & Gwazdauskas, F. C., Mar 1994, In : Animal Reproduction Science. 35, 1-2, p. 1-7 7 p.

Research output: Contribution to journalArticle

2 Scopus citations