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Xu Luo, PhD

  • 8418 Citations
  • 24 h-Index
1994 …2020

Research output per year

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Projects

Mechanism of Bax/Bak Activation During Apoptosis

Luo, X.

Project: Research project

Bax/Bak activation without direct activator BH3-only proteins in cancer cells

Luo, X.

Project: Research project

Mechanisms of Bax Activation

Luo, X.

National Institutes of Health

2/1/06 → 1/31/12

Project: Research project

    • Nebraska Center for Cellular Signaling

    Johnson, K. R., Simpson, M. A., Wahl, J. K., Caplan, S. H., Nawshad, A., Luo, X., Oakley, G. G., Furukawa, M., Wang, J., Lewis, R. E., Caplan, S. H., Naslavsky, N., Dong, J., Opavsky, R., Wahl, J. K., Solheim, J. C., Peng, A., Luo, X., Simpson, M. A., Wheelock, M., Koka, S., Dey, B., Hansen, L., Gladyshev, V. N., Nawaz, Z., Yaping, T., Wang, Z., Premaraj, S., Taylor, G. S., Tsai, M. & Mehta, P. P.

    National Institutes of Health

    9/19/03 → 6/30/13

    Project: Research project

    • Research Output

    • 8418 Citations
    • 24 h-Index
    • 35 Article
    • 1 Review article

    MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment

    Haschka, M. D., Karbon, G., Soratroi, C., O’Neill, K. L., Luo, X. & Villunger, A., Jan 1 2020, (Accepted/In press) In : Cell Death and Differentiation.

    Research output: Contribution to journal › Article

    Open Access

    • BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL

    Greaves, G., Milani, M., Butterworth, M., Carter, R. J., Byrne, D. P., Eyers, P. A., Luo, X., Cohen, G. M. & Varadarajan, S., Jun 1 2019, In : Cell Death and Differentiation. 26, 6, p. 1037-1047 11 p.

    Research output: Contribution to journal › Article

    • 17 Scopus citations

    BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis

    Huang, K., O’Neill, K. L., Li, J., Zhou, W., Han, N., Pang, X., Wu, W., Struble, L., Borgstahl, G., Liu, Z., Zhang, L. & Luo, X., Nov 1 2019, In : Cell Research. 29, 11, p. 942-952 11 p.

    Research output: Contribution to journal › Article

    • 8 Scopus citations

    CDK5 inhibitor downregulates Mcl-1 and sensitizes pancreatic cancer cell lines to navitoclax

    Kour, S., Rana, S., Contreras, J. I., King, H. M., Robb, C. M., Sonawane, Y. A., Bendjennat, M., Crawford, A. J., Barger, C. J., Kizhake, S., Luo, X., Hollingsworth, M. A. & Natarajan, A., Oct 2019, In : Molecular pharmacology. 96, 4, p. 419-429 11 p.

    Research output: Contribution to journal › Article

    Open Access
    • 2 Scopus citations

    DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis

    Milani, M., Beckett, A. J., Al-Zebeeby, A., Luo, X., Prior, I. A., Cohen, G. M. & Varadarajan, S., Dec 1 2019, In : Cell Death Discovery. 5, 1, 117.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations