Xu Luo, PhD

Associate Professor, Eppley Institute for Cancer Research
Courtesy Associate Professor, Pathology & Microbiology
Member, James O Armitage Center for Hematological Malignancies Research
Member, Fred & Pamela Buffett Cancer Center
Co-Core Leader, Center for Molecular Target Discovery & Development

Phone402-559-4643

Source: Scopus
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Bax/Bak activation without direct activator BH3-only proteins in cancer cells
Luo, X.
Project: Research project
Mechanism of Bax/Bak Activation During Apoptosis
Luo, X.
Project: Research project
Mechanisms of Bax Activation
Luo, X.
National Institutes of Health
2/1/06 → 1/31/12
Project: Research project
Nebraska Center for Cellular Signaling
Johnson, K. R., Simpson, M. A., Wahl, J. K., Caplan, S. H., Nawshad, A., Luo, X., Oakley, G. G., Furukawa, M., Wang, J., Lewis, R. E., Caplan, S. H., Naslavsky, N., Dong, J., Opavsky, R., Wahl, J. K., Solheim, J. C., Peng, A., Luo, X., Simpson, M. A., Wheelock, M., Koka, S., Dey, B., Hansen, L., Gladyshev, V. N., Nawaz, Z., Yaping, T., Wang, Z., Premaraj, S., Taylor, G. S., Tsai, M. & Mehta, P. P.
National Institutes of Health
9/19/03 → 6/30/13
Project: Research project

8581 Citations
24 h-Index
37 Article
2 Review article

BAX-dependent mitochondrial pathway mediates the crosstalk between ferroptosis and apoptosis
Lee, Y. S., Kalimuthu, K., Park, Y. S., Luo, X., Choudry, M. H. A., Bartlett, D. L. & Lee, Y. J., Oct 1 2020, In: Apoptosis. 25, 9-10, p. 625-631 7 p.
Research output: Contribution to journal › Article › peer-review
2 Scopus citations
MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment
Haschka, M. D., Karbon, G., Soratroi, C., O’Neill, K. L., Luo, X. & Villunger, A., Aug 1 2020, In: Cell Death and Differentiation. 27, 8, p. 2297-2312 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Scopus citations
The third model of Bax/Bak activation: A Bcl-2 family feud finally resolved?
Luo, X., O'Neill, K. L. & Huang, K., 2020, In: F1000Research. 9, 935.
Research output: Contribution to journal › Review article › peer-review

Open Access
3 Scopus citations
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition
Roca-Portoles, A., Rodriguez-Blanco, G., Sumpton, D., Cloix, C., Mullin, M., Mackay, G. M., O’Neill, K., Lemgruber, L., Luo, X. & Tait, S. W. G., Aug 1 2020, In: Cell Death and Disease. 11, 8, 616.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-X_L
Greaves, G., Milani, M., Butterworth, M., Carter, R. J., Byrne, D. P., Eyers, P. A., Luo, X., Cohen, G. M. & Varadarajan, S., Jun 1 2019, In: Cell Death and Differentiation. 26, 6, p. 1037-1047 11 p.
Research output: Contribution to journal › Article › peer-review
20 Scopus citations