Nanodevice for Digital Imaging of Palpable Structure at Human-Finger Resolution f

DESCRIPTION (provided by applicant): Based on clinical trials since 1963, it appears that breast examination (CBE) in combination with mammography may be the best strategy for high sensitivity and specificity in breast cancer screening provided CBE can be quantitative with digital (and standardized) reporting. Quantitative imaging of the palpable structure of the tumor may help decipher the abnormal changes in the breast and sentinel lymph nodes over time. An inexpensive, noninvasive screening tool with the ability to detect tumors as small as ~5mm could be used in a sequential approach to early detection. The long- term objective of this research is to develop a thin-film nanodevice, i.e., electronic skin, that will convert the pressure distribution on physical contact to light that can be imaged directly on a digital camera at a resolution on par with the human finger (~20