(Chemical Equation Presented) 1,2,4-trioxepanes, readily prepared and easily handled derivatives of aldehydes and ketones, are stable to a variety of synthetic conditions and yet easily deblocked with Zn/HOAc or Mg/MeOH to regenerate the parent carbonyl. Trioxepanes may provide an alternative to 1,3-dithianes for acid-stable protection of carbonyl groups.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Sep 30 2004|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry