Abstract
A number of 3-alkoxy-1,2-dioxolanes exhibit promising levels of antimalarial activity against Plasmodium falciparum. A new route to the 1,2-dioxolane core is reported based on tandem peroxidation/cyclization of enones.
Original language | English (US) |
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Pages (from-to) | 316-319 |
Number of pages | 4 |
Journal | ACS Medicinal Chemistry Letters |
Volume | 2 |
Issue number | 4 |
DOIs | |
State | Published - Apr 14 2011 |
Keywords
- 3-alkoxy-1,2-dioxolane
- Malaria
- dioxolane
- peroxide
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry