3D Bioprinting in Skeletal Muscle Tissue Engineering

Serge Ostrovidov, Sahar Salehi, Marco Costantini, Kasinan Suthiwanich, Majid Ebrahimi, Ramin Banan Sadeghian, Toshinori Fujie, Xuetao Shi, Stefano Cannata, Cesare Gargioli, Ali Tamayol, Mehmet Remzi Dokmeci, Gorka Orive, Wojciech Swieszkowski, Ali Khademhosseini

Research output: Contribution to journalReview articlepeer-review

227 Scopus citations

Abstract

Skeletal muscle tissue engineering (SMTE) aims at repairing defective skeletal muscles. Until now, numerous developments are made in SMTE; however, it is still challenging to recapitulate the complexity of muscles with current methods of fabrication. Here, after a brief description of the anatomy of skeletal muscle and a short state-of-the-art on developments made in SMTE with “conventional methods,” the use of 3D bioprinting as a new tool for SMTE is in focus. The current bioprinting methods are discussed, and an overview of the bioink formulations and properties used in 3D bioprinting is provided. Finally, different advances made in SMTE by 3D bioprinting are highlighted, and future needs and a short perspective are provided.

Original languageEnglish (US)
Article number1805530
JournalSmall
Volume15
Issue number24
DOIs
StatePublished - Jun 14 2019

Keywords

  • 3D printing
  • bioinks
  • bioprinting
  • hydrogels
  • skeletal muscle
  • tissue engineering

ASJC Scopus subject areas

  • Biotechnology
  • General Chemistry
  • Biomaterials
  • General Materials Science
  • Engineering (miscellaneous)

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