3D printed antibacterial prostheses

Jorge M. Zuniga

doi:10.3390/app8091651

3D printed antibacterial prostheses

Jorge M. Zuniga

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

The purpose of the current investigation was two-fold: (i) to describe the development of 3D printed prostheses using antibacterial filaments and (ii) to verify the antibacterial properties of the 3D printed prostheses. Three-dimensional printed finger prostheses were manufactured using PLACTIVE™ antibacterial 3D printing filaments. Two adults with left index finger amputations at the proximal phalanx were fitted with a customized 3D printed finger prosthesis manufactured with an antibacterial filament. The manual gross dexterity was assessed during the Box and Block Test. Patient satisfaction was assessed using the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST 2.0). Bacterial analysis of the 3D printed prostheses was performed by two independent laboratories against Staphylococcus aureus and Escherichia coli (ISO 22196). Two customized 3D printed partial finger prostheses were manufactured using a 3D printed antibacterial filament. The bacterial analysis showed that PLACTIVE™ with 1% antibacterial nanoparticles additives was up to 99.99% effective against Staphylococcus aureus and Escherichia coli. The manual gross dexterity assessed was improved after using the 3D printed partial finger prosthesis. The research subjects indicated that they were "quite satisfied" to "very satisfied" with the 3D printed partial finger prosthesis. The present investigation showed that the antibacterial 3D printed filament can be used for the development of functional and effective antibacterial finger prostheses.

Original language	English (US)
Article number	1651
Journal	Applied Sciences (Switzerland)
Volume	8
Issue number	9
DOIs	https://doi.org/10.3390/app8091651
State	Published - Sep 14 2018

Keywords

3D printing filament
Additive manufacturing
Antimicrobial material
Biocompatible material
Orthoses
Prosthetic design
Rapid prototyping
Upper-limb prosthetics

ASJC Scopus subject areas

Materials Science(all)
Instrumentation
Engineering(all)
Process Chemistry and Technology
Computer Science Applications
Fluid Flow and Transfer Processes

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10.3390/app8091651

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title = "3D printed antibacterial prostheses",

abstract = "The purpose of the current investigation was two-fold: (i) to describe the development of 3D printed prostheses using antibacterial filaments and (ii) to verify the antibacterial properties of the 3D printed prostheses. Three-dimensional printed finger prostheses were manufactured using PLACTIVE{\texttrademark} antibacterial 3D printing filaments. Two adults with left index finger amputations at the proximal phalanx were fitted with a customized 3D printed finger prosthesis manufactured with an antibacterial filament. The manual gross dexterity was assessed during the Box and Block Test. Patient satisfaction was assessed using the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST 2.0). Bacterial analysis of the 3D printed prostheses was performed by two independent laboratories against Staphylococcus aureus and Escherichia coli (ISO 22196). Two customized 3D printed partial finger prostheses were manufactured using a 3D printed antibacterial filament. The bacterial analysis showed that PLACTIVE{\texttrademark} with 1% antibacterial nanoparticles additives was up to 99.99% effective against Staphylococcus aureus and Escherichia coli. The manual gross dexterity assessed was improved after using the 3D printed partial finger prosthesis. The research subjects indicated that they were {"}quite satisfied{"} to {"}very satisfied{"} with the 3D printed partial finger prosthesis. The present investigation showed that the antibacterial 3D printed filament can be used for the development of functional and effective antibacterial finger prostheses.",

keywords = "3D printing filament, Additive manufacturing, Antimicrobial material, Biocompatible material, Orthoses, Prosthetic design, Rapid prototyping, Upper-limb prosthetics",

author = "Zuniga, {Jorge M.}",

note = "Funding Information: Funding: This study was partially funded by the National Institutes of Health (P20GM109090–01), the Center for Research in Human Movement Variability at the Biomechanics Research Building at The University of Nebraska at Omaha, the Teacher-Researcher Partnership Program (TRPP), the University of Nebraska Science Collaboration Initiative, and NASA Nebraska Space Grant Office. The APC was funded by the University of Nebraska Science Collaboration Initiative. Publisher Copyright: {\textcopyright} 2018 by the authors.",

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doi = "10.3390/app8091651",

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N1 - Funding Information: Funding: This study was partially funded by the National Institutes of Health (P20GM109090–01), the Center for Research in Human Movement Variability at the Biomechanics Research Building at The University of Nebraska at Omaha, the Teacher-Researcher Partnership Program (TRPP), the University of Nebraska Science Collaboration Initiative, and NASA Nebraska Space Grant Office. The APC was funded by the University of Nebraska Science Collaboration Initiative. Publisher Copyright: © 2018 by the authors.

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N2 - The purpose of the current investigation was two-fold: (i) to describe the development of 3D printed prostheses using antibacterial filaments and (ii) to verify the antibacterial properties of the 3D printed prostheses. Three-dimensional printed finger prostheses were manufactured using PLACTIVE™ antibacterial 3D printing filaments. Two adults with left index finger amputations at the proximal phalanx were fitted with a customized 3D printed finger prosthesis manufactured with an antibacterial filament. The manual gross dexterity was assessed during the Box and Block Test. Patient satisfaction was assessed using the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST 2.0). Bacterial analysis of the 3D printed prostheses was performed by two independent laboratories against Staphylococcus aureus and Escherichia coli (ISO 22196). Two customized 3D printed partial finger prostheses were manufactured using a 3D printed antibacterial filament. The bacterial analysis showed that PLACTIVE™ with 1% antibacterial nanoparticles additives was up to 99.99% effective against Staphylococcus aureus and Escherichia coli. The manual gross dexterity assessed was improved after using the 3D printed partial finger prosthesis. The research subjects indicated that they were "quite satisfied" to "very satisfied" with the 3D printed partial finger prosthesis. The present investigation showed that the antibacterial 3D printed filament can be used for the development of functional and effective antibacterial finger prostheses.

AB - The purpose of the current investigation was two-fold: (i) to describe the development of 3D printed prostheses using antibacterial filaments and (ii) to verify the antibacterial properties of the 3D printed prostheses. Three-dimensional printed finger prostheses were manufactured using PLACTIVE™ antibacterial 3D printing filaments. Two adults with left index finger amputations at the proximal phalanx were fitted with a customized 3D printed finger prosthesis manufactured with an antibacterial filament. The manual gross dexterity was assessed during the Box and Block Test. Patient satisfaction was assessed using the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST 2.0). Bacterial analysis of the 3D printed prostheses was performed by two independent laboratories against Staphylococcus aureus and Escherichia coli (ISO 22196). Two customized 3D printed partial finger prostheses were manufactured using a 3D printed antibacterial filament. The bacterial analysis showed that PLACTIVE™ with 1% antibacterial nanoparticles additives was up to 99.99% effective against Staphylococcus aureus and Escherichia coli. The manual gross dexterity assessed was improved after using the 3D printed partial finger prosthesis. The research subjects indicated that they were "quite satisfied" to "very satisfied" with the 3D printed partial finger prosthesis. The present investigation showed that the antibacterial 3D printed filament can be used for the development of functional and effective antibacterial finger prostheses.

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3D printed antibacterial prostheses

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Keywords

ASJC Scopus subject areas

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