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  • Howard S Fox
2020

Age-related visual dynamics in HIV-infected adults with cognitive impairment

Groff, B. R., Wiesman, A. I., Rezich, M. T., O'Neill, J., Robertson, K. R., Fox, H. S., Swindells, S. & Wilson, T. W., May 1 2020, In : Neurology(R) neuroimmunology & neuroinflammation. 7, 3

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A year-long extended release nanoformulated cabotegravir prodrug

Kulkarni, T. A., Bade, A. N., Sillman, B., Shetty, B. L. D., Wojtkiewicz, M. S., Gautam, N., Hilaire, J. R., Sravanam, S., Szlachetka, A., Lamberty, B. G., Morsey, B. M., Fox, H. S., Alnouti, Y., McMillan, J. E. M., Mosley, R. L., Meza, J., Domanico, P. L., Yue, T. Y., Moore, G., Edagwa, B. J. & 1 others, Gendelman, H. E., Jan 1 2020, (Accepted/In press) In : Nature Materials.

Research output: Contribution to journalArticle

Epigenetic Markers of Aging Predict the Neural Oscillations Serving Selective Attention

Wiesman, A. I., Rezich, M. T., O'Neill, J., Morsey, B., Wang, T., Ideker, T., Swindells, S., Fox, H. S. & Wilson, T. W., Mar 14 2020, In : Cerebral Cortex. 30, 3, p. 1234-1243 10 p.

Research output: Contribution to journalArticle

HIV-1 tat-mediated astrocytic amyloidosis involves the HIF-1α/lncRNA BACE1-AS axis

Sil, S., Hu, G., Liao, K., Niu, F., Callen, S., Periyasamy, P., Fox, H. S. & Buch, S., May 1 2020, In : PLoS biology. 18, 5, e3000660.

Research output: Contribution to journalArticle

Open Access
2019

A mouse model of seizures in anti–N-methyl-d-aspartate receptor encephalitis

Taraschenko, O., Fox, H. S., Pittock, S. J., Zekeridou, A., Gafurova, M., Eldridge, E., Liu, J., Dravid, S. M. & Dingledine, R., Mar 2019, In : Epilepsia. 60, 3, p. 452-463 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Creation of a long-acting rilpivirine prodrug nanoformulation

Hilaire, J. R., Bade, A. N., Sillman, B., Gautam, N., Herskovitz, J., Dyavar Shetty, B. L., Wojtkiewicz, M. S., Szlachetka, A., Lamberty, B. G., Sravanam, S., Fox, H. S., Alnouti, Y., Dash, P. K., McMillan, J. E. M., Edagwa, B. J. & Gendelman, H. E., Oct 2019, In : Journal of Controlled Release. 311-312, p. 201-211 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Defining cerebrospinal fluid HIV RNA escape: Editorial review AIDS

Winston, A., Antinori, A., Cinque, P., Fox, H. S., Gisslen, M., Henrich, T. J., Letendre, S., Persaud, D., Price, R. W. & Spudich, S., Dec 1 2019, In : AIDS. 33, p. S107-S111

Research output: Contribution to journalReview article

Direct contacts of microglia on myelin sheath and Ranvier’s node in the corpus callosum in rats

Zhang, J., Yang, X., Zhou, Y., Fox, H. & Xiong, H., Jan 1 2019, In : Journal of Biomedical Research. 33, 3, p. 192-200 9 p.

Research output: Contribution to journalArticle

Downregulation of an evolutionary young mir-1290 in an ipscderived neural stem cell model of autism spectrum disorder

Moore, D., Meays, B. M., Madduri, L. S. V., Shahjin, F., Chand, S., Niu, M., Albahrani, A., Guda, C., Pendyala, G., Fox, H. S. & Yelamanchili, S. V., Jan 1 2019, In : Stem Cells International. 2019, 8710180.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Pharmacokinetic testing of a first-generation cabotegravir prodrug in rhesus macaques

McMillan, J., Szlachetka, A., Zhou, T., Morsey, B., Lamberty, B., Callen, S., Gautam, N., Alnouti, Y., Edagwa, B., Gendelman, H. E. & Fox, H. S., Mar 1 2019, In : AIDS. 33, 3, p. 585-588 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
2 Scopus citations

Secreted Metabolome of Human Macrophages Exposed to Methamphetamine

Pawlak, K., Lech, K., Vei, A., Burch, S., Zieschang, S., Jaquet, S., Yu, F., Harwood, E., Morsey, B., Fox, H. S. & Ciborowski, P., Jun 20 2019, In : Analytical chemistry. 91, 14, p. 9190-9197 8 p.

Research output: Contribution to journalArticle

The integrated National NeuroAIDS Tissue Consortium database: A rich platform for neuroHIV research

Heithoff, A. J., Totusek, S. A., Le, D., Barwick, L., Gensler, G., Franklin, D. R., Dye, A. C., Pandey, S., Sherman, S., Guda, C. & Fox, H. S., Jan 8 2019, In : Database. 2019, bay134.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Aberrant occipital dynamics differentiate HIV-infected patients with and without cognitive impairment

Wiesman, A. I., O'Neill, J., Mills, M. S., Robertson, K. R., Fox, H. S., Swindells, S. & Wilson, T. W., Jun 1 2018, In : Brain. 141, 6, p. 1678-1690 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Aberrant oscillatory dynamics during somatosensory processing in HIV-infected adults

Spooner, R. K., Wiesman, A. I., Mills, M. S., O'Neill, J., Robertson, K. R., Fox, H. S., Swindells, S. & Wilson, T. W., Jan 1 2018, In : NeuroImage: Clinical. 20, p. 85-91 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles

Zhou, T., Su, H., Dash, P., Lin, Z., Dyavar Shetty, B. L., Kocher, T., Szlachetka, A., Lamberty, B., Fox, H. S., Poluektova, L., Gorantla, S., McMillan, J. E., Gautam, N., Mosley, R. L., Alnouti, Y., Edagwa, B. & Gendelman, H. E., Jan 2018, In : Biomaterials. 151, p. 53-65 13 p.

Research output: Contribution to journalArticle

36 Scopus citations

Erratum: Correction: MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease (PLoS pathogens (2015) 11 7 (e1005032))

Yelamanchili, S. V., Lamberty, B. G., Rennard, D. A., Morsey, B. M., Hochfelder, C. G., Meays, B. M., Levy, E. & Fox, H. S., May 1 2018, In : PLoS pathogens. 14, 5, p. e1007068

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Molecular mechanisms of long noncoding RNAs and their role in disease pathogenesis

Hu, G., Niu, F., Humburg, B. A., Liao, K., Bendi, S., Callen, S., Fox, H. S. & Buch, S., Apr 1 2018, In : Oncotarget. 9, 26, p. 18648-18663 16 p.

Research output: Contribution to journalReview article

39 Scopus citations

Multimodal theranostic nanoformulations permit magnetic resonance bioimaging of antiretroviral drug particle tissue-cell biodistribution

Kevadiya, B. D., Woldstad, C., Ottemann, B. M., Dash, P., Sajja, B. R., Lamberty, B., Morsey, B., Kocher, T., Dutta, R., Bade, A. N., Liu, Y., Callen, S. E., Fox, H. S., Byrareddy, S. N., McMillan, J. E. M., Bronich, T. K., Edagwa, B. J., Boska, M. D. & Gendelman, H. E., Jan 1 2018, In : Theranostics. 8, 1, p. 256-276 21 p.

Research output: Contribution to journalArticle

22 Scopus citations

Neural dynamics of selective attention deficits in HIV-associated neurocognitive disorder

Lew, B. J., McDermott, T. J., Wiesman, A. I., O'Neill, J., Mills, M. S., Robertson, K. R., Fox, H. S., Swindells, S. & Wilson, T. W., Jan 1 2018, In : Neurology. 91, 20, p. E1860-E1869

Research output: Contribution to journalArticle

9 Scopus citations

Pharmacokinetics of a long-acting nanoformulated dolutegravir prodrug in rhesus macaques

McMillan, J. E., Szlachetka, A., Slack, L., Sillman, B., Lamberty, B., Morsey, B., Callen, S., Gautam, N., Alnouti, Y., Edagwa, B., Gendelman, H. E. & Fox, H. S., Jan 2018, In : Antimicrobial Agents and Chemotherapy. 62, 1, e01316-17.

Research output: Contribution to journalArticle

16 Scopus citations

Proteomic and functional data sets on synaptic mitochondria from rats with genetic ablation of Parkin

Villeneuve, L. M., Stauch, K. L., Purnell, P. S. & Fox, H. S., Oct 2018, In : Data in Brief. 20, p. 568-572 5 p.

Research output: Contribution to journalArticle

Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain

Bortell, N., Basova, L., Najera, J. A., Morsey, B., Fox, H. S. & Marcondes, M. C. G., Jun 1 2018, In : Journal of Neuroimmune Pharmacology. 13, 2, p. 163-178 16 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Aberrant Neuronal Dynamics during Working Memory Operations in the Aging HIV-Infected Brain

Wilson, T. W., Proskovec, A. L., Heinrichs-Graham, E., O'Neill, J., Robertson, K. R., Fox, H. S. & Swindells, S., Feb 3 2017, In : Scientific reports. 7, 41568.

Research output: Contribution to journalArticle

20 Scopus citations

Astrocyte-specific overexpressed gene signatures in response to methamphetamine exposure in vitro

Bortell, N., Basova, L., Semenova, S., Fox, H. S., Ravasi, T. & Marcondes, M. C. G., Mar 9 2017, In : Journal of Neuroinflammation. 14, 1, 49.

Research output: Contribution to journalArticle

12 Scopus citations

Central nervous system-penetrating antiretrovirals impair energetic reserve in striatal nerve terminals

Stauch, K. L., Emanuel, K., Lamberty, B. G., Morsey, B. & Fox, H. S., Dec 1 2017, In : Journal of neurovirology. 23, 6, p. 795-807 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Induction of miR-155 after brain injury promotes type 1 interferon and has a neuroprotective effect

Harrison, E. B., Emanuel, K., Lamberty, B. G., Morsey, B. M., Li, M., Kelso, M. L., Yelamanchili, S. V. & Fox, H. S., Jul 28 2017, In : Frontiers in Molecular Neuroscience. 10, 228.

Research output: Contribution to journalArticle

18 Scopus citations

Measures of Physical and Mental Independence among HIV-Positive Individuals: Impact of Substance Use Disorder

Christensen, B., Qin, Z., Byrd, D. A., Yu, F., Morgello, S., Gelman, B. B., Moore, D. J., Grant, I., Singer, E. J., Fox, H. S. & Baccaglini, L., Oct 2017, In : AIDS Research and Human Retroviruses. 33, 10, p. 1048-1055 8 p.

Research output: Contribution to journalArticle

Modifications in acute phase and complement systems predict shifts in cognitive status of HIV-infected patients

Ubaida-Mohien, C., Lamberty, B., Dickens, A. M., Mielke, M. M., Marcotte, T., Sacktor, N., Grant, I., Letendre, S., Franklin, D., Cibrowski, P., Tharakan, R., McArthur, J. C., Fox, H. & Haughey, N. J., Jun 19 2017, In : AIDS. 31, 10, p. 1365-1378 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Osteopontin Impacts West Nile virus Pathogenesis and Resistance by Regulating Inflammasome Components and Cell Death in the Central Nervous System at Early Time Points

Bortell, N., Flynn, C., Conti, B., Fox, H. S. & Marcondes, M. C. G., Jan 1 2017, In : Mediators of Inflammation. 2017, 7582437.

Research output: Contribution to journalArticle

2 Scopus citations

Proteomic analysis of neuronal mitochondria

Stauch, K. L. & Fox, H. S., Jan 1 2017, Neuromethods. Humana Press Inc., p. 299-319 21 p. (Neuromethods; vol. 123).

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations
2016

Early Expression of Parkinson’s Disease-Related Mitochondrial Abnormalities in PINK1 Knockout Rats

Villeneuve, L. M., Purnell, P. R., Boska, M. D. & Fox, H. S., Jan 1 2016, In : Molecular Neurobiology. 53, 1, p. 171-186 16 p.

Research output: Contribution to journalArticle

37 Scopus citations

Emerging roles of extracellular vesicles in neurodegenerative disorders: Focus on HIV-associated neurological complications

Hu, G., Yang, L., Cai, Y., Niu, F., Mezzacappa, F., Callen, S., Fox, H. S. & Buch, S., Jan 1 2016, In : Cell Death and Disease. 7, 11, e2481.

Research output: Contribution to journalReview article

15 Scopus citations

HIV-1 transgenic rats display mitochondrial abnormalities consistent with abnormal energy generation and distribution

Villeneuve, L. M., Purnell, P. R., Stauch, K. L., Callen, S. E., Buch, S. J. & Fox, H. S., Oct 1 2016, In : Journal of neurovirology. 22, 5, p. 564-574 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

HIV-associated neurocognitive disorders

Fox, H. & Purnell, P., Jan 1 2016, Neuroimmune Pharmacology. Springer International Publishing, p. 407-420 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations

Metabolic drift in the aging brain

Ivanisevic, J., Stauch, K. L., Petrascheck, M., Benton, H. P., Epstein, A. A., Fang, M., Gorantla, S., Tran, M., Hoang, L., Kurczy, M. E., Boska, M. D., Gendelman, H. E., Fox, H. S. & Siuzdak, G., Jan 1 2016, In : Aging. 8, 5, p. 1000-1020 21 p.

Research output: Contribution to journalArticle

32 Scopus citations

Methamphetamine abuse affects gene expression in brain-derived microglia of SIV-infected macaques to enhance inflammation and promote virus targets

Najera, J. A., Bustamante, E. A., Bortell, N., Morsey, B., Fox, H. S., Ravasi, T. & Marcondes, M. C. G., Jan 1 2016, In : BMC Immunology. 17, 1, 7.

Research output: Contribution to journalArticle

16 Scopus citations

Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA

Gross, A. M., Jaeger, P. A., Kreisberg, J. F., Licon, K., Jepsen, K. L., Khosroheidari, M., Morsey, B. M., Swindells, S., Shen, H., Ng, C. T., Flagg, K., Chen, D., Zhang, K., Fox, H. S. & Ideker, T., Apr 21 2016, In : Molecular Cell. 62, 2, p. 157-168 12 p.

Research output: Contribution to journalArticle

81 Scopus citations

Neonatal mitochondrial abnormalities due to PINK1 deficiency: Proteomics reveals early changes relevant to Parkinson's disease

Villeneuve, L. M., Purnell, P. R., Stauch, K. L. & Fox, H. S., Mar 1 2016, In : Data in Brief. 6, p. 428-432 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Proteomics and HIV

Ciborowski, P. S. & Fox, H. S., Feb 1 2016, In : Proteomics - Clinical Applications. 10, 2, 1 p.

Research output: Contribution to journalEditorial

1 Scopus citations

SWATH-MS proteome profiling data comparison of DJ-1, Parkin, and PINK1 knockout rat striatal mitochondria

Stauch, K. L., Villeneuve, L. M., Purnell, P. R., Pandey, S., Guda, C. & Fox, H. S., Dec 2016, In : Data in Brief. 9, p. 589-593 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

The proteomic characterization of plasma or serum from HIV-infected patients

Haverland, N. A., Villeneuve, L. M., Ciborowski, P. S. & Fox, H. S., Jan 1 2016, Methods in Molecular Biology. Humana Press Inc., p. 293-310 18 p. (Methods in Molecular Biology; vol. 1354).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Traumatic brain injury increases levels of miR-21 in extracellular vesicles: Implications for neuroinflammation

Harrison, E. B., Hochfelder, C. G., Lamberty, B. G., Meays, B. M., Morsey, B. M., Kelso, M. L., Fox, H. S. & Yelamanchili, S. V., Jan 1 2016, In : FEBS Open Bio. 6, 8, p. 835-846 12 p.

Research output: Contribution to journalArticle

Open Access
45 Scopus citations