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  • Samuel Monroe Cohen
2020

An Evaluation of the Human Relevance of the Liver Tumors Observed in Female Mice Treated with Permethrin Based on Mode of Action

Kondo, M., Kikumoto, H., Osimitz, T. G., Cohen, S. M., Lake, B. G. & Yamada, T., May 1 2020, In : Toxicological Sciences. 175, 1, p. 50-63 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

An Interesting and Productive Research and Clinical Career

Cohen, S. M., May 1 2020, In : International Journal of Toxicology. 39, 3, p. 182-188 7 p.

Research output: Contribution to journalArticle

Cell proliferation analysis is a reliable predictor of lack of carcinogenicity: Case study using the pyrethroid imiprothrin on lung tumorigenesis in mice

Kawamoto, K., Ogata, K., Asano, H., Miyata, K., Sukata, T., Utsumi, T., Cohen, S. M. & Yamada, T., Jun 2020, In : Regulatory Toxicology and Pharmacology. 113, 104646.

Research output: Contribution to journalArticle

1 Scopus citations

Cotinine, a major nicotine metabolite, induces cell proliferation on urothelium in vitro and in vivo

Suzuki, S., Cohen, S. M., Arnold, L. L., Pennington, K. L., Kato, H., Naiki, T., Naiki-Ito, A., Yamashita, Y. & Takahashi, S., Jan 15 2020, In : Toxicology. 429, 152325.

Research output: Contribution to journalArticle

1 Scopus citations

Expression of Hematopoietic Stem and Endothelial Cell Markers in Canine Hemangiosarcoma

Kakiuchi-Kiyota, S., Obert, L. A., Crowell, D. M., Xia, S., Roy, M. D., Coskran, T. M., Kreeger, J. M., Crabbs, T. A., Cohen, S. M., Cattley, R. C. & Cook, J. C., Apr 1 2020, In : Toxicologic Pathology. 48, 3, p. 481-493 13 p.

Research output: Contribution to journalArticle

FEMA GRAS assessment of natural flavor complexes: Cinnamomum and Myroxylon-derived flavoring ingredients

Rietjens, I. M. C. M., Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rosol, T. J., Davidsen, J. M., Harman, C. L., Murray, I. J. & Taylor, S. V., Jan 2020, In : Food and Chemical Toxicology. 135, 110949.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

FEMA GRAS assessment of natural flavor complexes: Mint, buchu, dill and caraway derived flavoring ingredients

Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Bastaki, M., Davidsen, J. M., Harman, C. L., McGowen, M. M. & Taylor, S. V., Jan 2020, In : Food and Chemical Toxicology. 135, 110870.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Relevance of mouse lung tumors to human risk assessment

Cohen, S. M., Zhongyu, Y. & Bus, J. S., Jul 3 2020, In : Journal of Toxicology and Environmental Health - Part B: Critical Reviews. 23, 5, p. 214-241 28 p.

Research output: Contribution to journalReview article

The safety evaluation of food flavoring substances: the role of genotoxicity studies

Gooderham, N. J., Cohen, S. M., Eisenbrand, G., Fukushima, S., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Rosol, T. J., Bastaki, M., Linman, M. J. & Taylor, S. V., Jan 2 2020, In : Critical reviews in toxicology. 50, 1, p. 1-27 27 p.

Research output: Contribution to journalReview article

Open Access
4 Scopus citations
2019

Alendronate-Modified Polymeric Micelles for the Treatment of Breast Cancer Bone Metastasis

Liu, T., Romanova, S., Wang, S., Hyun, M. A., Zhang, C., Cohen, S. M., Singh, R. K. & Bronich, T. K., Jan 1 2019, In : Molecular Pharmaceutics.

Research output: Contribution to journalArticle

Chemical carcinogenicity revisited 1: A unified theory of carcinogenicity based on contemporary knowledge

Wolf, D. C., Cohen, S. M., Boobis, A. R., Dellarco, V. L., Fenner-Crisp, P. A., Moretto, A., Pastoor, T. P., Schoeny, R. S., Seed, J. G. & Doe, J. E., Apr 2019, In : Regulatory Toxicology and Pharmacology. 103, p. 86-92 7 p.

Research output: Contribution to journalComment/debate

14 Scopus citations

Chemical carcinogenicity revisited 3: Risk assessment of carcinogenic potential based on the current state of knowledge of carcinogenesis in humans

Cohen, S. M., Boobis, A. R., Dellarco, V. L., Doe, J. E., Fenner-Crisp, P. A., Moretto, A., Pastoor, T. P., Schoeny, R. S., Seed, J. G. & Wolf, D. C., Apr 2019, In : Regulatory Toxicology and Pharmacology. 103, p. 100-105 6 p.

Research output: Contribution to journalComment/debate

15 Scopus citations

Dose-response for assessing the cancer risk of inorganic arsenic in drinking water: the scientific basis for use of a threshold approach

Tsuji, J. S., Chang, E. T., Gentry, P. R., Clewell, H. J., Boffetta, P. & Cohen, S. M., Jan 2 2019, In : Critical reviews in toxicology. 49, 1, p. 36-84 49 p.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations

Editorial

Aschner, M., Autrup, H. N., Cohen, S. M., Dekant, W., Eisenbrand, G., Galli, C. L., Gori, G. B., Kaminski, N. E., Klaassen, C. D., Klaunig, J. E., Levy, L., Lotti, M., Marquardt, H. WJ., Pelkonen, O., Schrenk, D. F. & Yamazaki, H., Feb 2019, In : Regulatory Toxicology and Pharmacology. 101, p. A1-A2

Research output: Contribution to journalEditorial

Evaluation of immunologic and intestinal effects in rats administered an E 171-containing diet, a food grade titanium dioxide (TiO2)

Blevins, L. K., Crawford, R. B., Bach, A., Rizzo, M. D., Zhou, J., Henriquez, J. E., Khan, D. M. I. O., Sermet, S., Arnold, L. L., Pennington, K. L., Souza, N. P., Cohen, S. M. & Kaminski, N. E., Nov 2019, In : Food and Chemical Toxicology. 133, 110793.

Research output: Contribution to journalArticle

5 Scopus citations

Experimental cryptorchidism enhances testicular susceptibility to dibutyl phthalate or acrylamide in Sprague-Dawley rats

de Souza, N. P., Cardoso, AP. F., Gomide, L. M. M., Lima, T. R. R., Miot, H. A., Martino-Andrade, A. J., Arnold, L. L., Pennington, K. L., Cohen, S. M., de Camargo, J. L. V. & Nascimento e Pontes, M. G., Aug 1 2019, In : Human and Experimental Toxicology. 38, 8, p. 899-913 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

FEMA GRAS assessment of natural flavor complexes: Citrus-derived flavoring ingredients

Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Bastaki, M., Davidsen, J. M., Harman, C. L., McGowen, M. & Taylor, S. V., Feb 2019, In : Food and Chemical Toxicology. 124, p. 192-218 27 p.

Research output: Contribution to journalArticle

6 Scopus citations

Inorganic arsenic: a nongenotoxic threshold carcinogen

Cohen, S. M., Arnold, L. L. & Tsuji, J. S., Apr 2019, In : Current Opinion in Toxicology. 14, p. 8-13 6 p.

Research output: Contribution to journalReview article

1 Scopus citations

Involvement of Peroxisome Proliferator-Activated Receptor-Alpha in Liver Tumor Production by Permethrin in the Female Mouse

Kondo, M., Miyata, K., Nagahori, H., Sumida, K., Osimitz, T. G., Cohen, S. M., Lake, B. G. & Yamada, T., Apr 1 2019, In : Toxicological Sciences. 168, 2, p. 572-596 25 p.

Research output: Contribution to journalArticle

2 Scopus citations

Isolation and molecular characterization of spermatogonia from male Sprague-Dawley rats exposed in utero and postnatally to dibutyl phthalate or acrylamide

Souza, N. P., Arnold, L. L., Pennington, K. L., Nascimento e Pontes, M. G., Miot, H. A., de Camargo, J. L. V. & Cohen, S. M., Sep 2 2019, In : Toxicology Mechanisms and Methods. 29, 7, p. 488-498 11 p.

Research output: Contribution to journalArticle

Mitochondrial lipid droplet formation as a detoxification mechanism to sequester and degrade excessive urothelial membranes

Liao, Y., Tham, D. K. L., Liang, F. X., Chang, J., Wei, Y., Sudhir, P. R., Sall, J., Ren, S. J., Chicote, J. U., Arnold, L. L., Hu, C. C. A., Romih, R., Andrade, L. R., Rindler, M. J., Cohen, S. M., DeSalle, R., Garcia-España, A., Ding, M., Wu, X. R. & Sun, T. T., Nov 15 2019, In : Molecular biology of the cell. 30, 24, p. 2969-2984 16 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Small bowel obstruction exacerbated by barium sulfate administration

Reid, W. L., Cox, J. L., Pennington, K. L., McCarthy, P., Kothari, V. M. & Cohen, S. M., Sep 2019, In : Human Pathology: Case Reports. 17, 200315.

Research output: Contribution to journalArticle

Open Access

Toxicological evaluation of carcinogenicity of the pyrethroid imiprothrin in rats and mice

Yamada, T., Asano, H., Miyata, K., Rhomberg, L. R., Haseman, J. K., Greaves, P., Greim, H., Berry, C. & Cohen, S. M., Jul 2019, In : Regulatory Toxicology and Pharmacology. 105, p. 1-14 14 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Antiretroviral drug metabolism in humanized PXR-CAR-CYP3A-NOG mice

McMillan, J. E. M., Cobb, D. A., Lin, Z., Banoub, M. G., Dagur, R. S., Branch Woods, A. A., Wang, W., Makarov, E., Kocher, T., Joshi, P. S., Quadros, R. M., Harms, D. W., Cohen, S. M., Gendelman, H. E., Gurumurthy, C. B., Gorantla, S. & Poluektova, L. Y., May 2018, In : Journal of Pharmacology and Experimental Therapeutics. 365, 2, p. 272-280 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Crystalluria and Chronic Kidney Disease

Cohen, S. M., Dec 1 2018, In : Toxicologic Pathology. 46, 8, p. 949-955 7 p.

Research output: Contribution to journalArticle

Effect of polyhexamethylene biguanide on rat liver

Chowdhury, A., Arnold, L. L., Wang, Z., Pennington, K. L., Dodmane, P., Farragut-Cardoso, A. P., Klaunig, J. E., Cros, D., Creppy, E. E. & Cohen, S. M., Mar 15 2018, In : Toxicology Letters. 285, p. 94-103 10 p.

Research output: Contribution to journalArticle

Epithelium Lining Rat Renal Papilla: Nomenclature and Association with Chronic Progressive Nephropathy (CPN)

Souza, N. P., Hard, G. C., Arnold, L. L., Foster, K. W., Pennington, K. L. & Cohen, S. M., Apr 1 2018, In : Toxicologic Pathology. 46, 3, p. 266-272 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Indocyanine green loaded hyaluronan-derived nanoparticles for fluorescence-enhanced surgical imaging of pancreatic cancer

Qi, B., Crawford, A. J., Wojtynek, N. E., Holmes, M. B., Souchek, J. J., Almeida-Porada, G., Ly, Q. P., Cohen, S. M., Hollingsworth, M. A. & Mohs, A. M., Apr 2018, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 3, p. 769-780 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Letter to the editor, re: Lynch et al., 2017

Cohen, S. M., Feb 2018, In : Environment International. 1 p.

Research output: Contribution to journalLetter

1 Scopus citations

Obfuscating transparency?

Aschner, M., Autrup, H., Berry, C. L., Boobis, A. R., Cohen, S. M., Dekant, W., Galli, C. L., Goodman, J. I., Gori, G. B., Greim, H. A., Kaminski, N. E., Klaassen, C. D., Klaunig, J. E., Lotti, M., Marquardt, H. WJ., Moretto, A., Pelkonen, O., Sipes, I. G., Wallace, K. B. & Yamazaki, H., Aug 2018, In : Regulatory Toxicology and Pharmacology. 97, p. A1-A3

Research output: Contribution to journalEditorial

Orally administered nicotine effects on rat urinary bladder proliferation and carcinogenesis

Suzuki, S., Cohen, S. M., Arnold, L. L., Kato, H., Fuji, S., Pennington, K. L., Nagayasu, Y., Naiki-Ito, A., Yamashita, Y. & Takahashi, S., Apr 1 2018, In : Toxicology. 398-399, p. 31-40 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Screening for human urinary bladder carcinogens: two-year bioassay is unnecessary

Cohen, S. M., Jan 1 2018, In : Toxicology Research. 7, 4, p. 565-575 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

The safety evaluation of food flavouring substances: the role of metabolic studies

Smith, R. L., Cohen, S. M., Fukushima, S., Gooderham, N. J., Hecht, S. S., Guengerich, F. P., Rietjens, I. M. C. M., Bastaki, M., Harman, C. L., McGowen, M. M. & Taylor, S. V., Jan 1 2018, In : Toxicology Research. 7, 4, p. 618-646 29 p.

Research output: Contribution to journalReview article

6 Scopus citations

Updated procedure for the safety evaluation of natural flavor complexes used as ingredients in food

Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Davidsen, J. M., Harman, C. L. & Taylor, S. V., Mar 2018, In : Food and Chemical Toxicology. 113, p. 171-178 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
2017

An evaluation of the human relevance of the lung tumors observed in female mice treated with permethrin based on mode of action

Yamada, T., Kondo, M., Miyata, K., Ogata, K., Kushida, M., Sumida, K., Kawamura, S., Osimitz, T. G., Lake, B. G. & Cohen, S. M., Jan 1 2017, In : Toxicological Sciences. 157, 2, p. 465-486 22 p.

Research output: Contribution to journalArticle

11 Scopus citations

Editor's highlight: Mode of action analysis for rat hepatocellular tumors produced by the synthetic pyrethroid momfluorothrin: Evidence for activation of the constitutive androstane receptor and mitogenicity in rat hepatocytes

Okuda, Y., Kushida, M., Sumida, K., Nagahori, H., Nakamura, Y., Higuchi, H., Kawamura, S., Lake, B. G., Cohen, S. M. & Yamada, T., Aug 1 2017, In : Toxicological Sciences. 158, 2, p. 412-430 19 p., kfx102.

Research output: Contribution to journalArticle

10 Scopus citations

Evaluation of the human relevance of the constitutive androstane receptor-mediated mode of action for rat hepatocellular tumor formation by the synthetic pyrethroid momfluorothrin

Okuda, Y., Kushida, M., Kikumoto, H., Nakamura, Y., Higuchi, H., Kawamura, S., Cohen, S. M., Lake, B. G. & Yamada, T., Dec 2017, In : Journal of Toxicological Sciences. 42, 6, p. 773-788 16 p.

Research output: Contribution to journalArticle

11 Scopus citations

Low-dose dose-response for reduced cell viability after exposure of human keratinocyte (HEK001) cells to arsenite

Bogen, K. T., Arnold, L. L., Chowdhury, A., Pennington, K. L. & Cohen, S. M., Jan 1 2017, In : Toxicology Reports. 4, p. 32-38 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Pathology of bladder cancer

Bryan, G. T. & Cohen, S. M., Jan 1 2017, CRC Press. 191 p.

Research output: Book/ReportBook

Pathology of bladder cancer

Bryan, G. T. & Cohen, S. M., Jan 1 2017, CRC Press. 236 p.

Research output: Book/ReportBook

5 Scopus citations

Pathology of experimental bladder cancer in rodents

Cohen, S. M., Jan 1 2017, Pathology of Bladder Cancer. CRC Press, p. 1-40 40 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

55 Scopus citations

Pathology of human bladder cancer and related lesions

Friedell, G. H., Nagy, G. K. & Cohen, S. M., Jan 1 2017, Pathology of Bladder Cancer. CRC Press, p. 11-42 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations

Preface

Bryan, G. T. & Cohen, S. M., Jan 1 2017, Pathology of Bladder Cancer. CRC Press, p. iii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Preface

Bryan, G. T. & Cohen, S. M., Jan 1 2017, Pathology of Bladder Cancer. CRC Press, p. iii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Response to Druwe and Burgoon, 2016 Letter to the Editor in Archives of Toxicology

Cohen, S. M., Goodman, J. I., Klaunig, J. E. & Arnold, L. L., Feb 1 2017, In : Archives of Toxicology. 91, 2, p. 999-1000 2 p.

Research output: Contribution to journalEditorial

2 Scopus citations

Response to Loomis et al Comment on Boobis et al

Boobis, A. R., Cohen, S. M., Dellarco, V. L., Doe, J. E., Fenner-Crisp, P. A., Moretto, A., Pastoor, T. P., Schoeny, R. S., Seed, J. G. & Wolf, D. C., Aug 2017, In : Regulatory Toxicology and Pharmacology. 88, p. 358-359 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Safety evaluation of substituted thiophenes used as flavoring ingredients

Cohen, S. M., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Smith, R. L., Bastaki, M., Harman, C. L., McGowen, M. M., Valerio, L. G. & Taylor, S. V., Jan 1 2017, In : Food and Chemical Toxicology. 99, p. 40-59 20 p.

Research output: Contribution to journalReview article

10 Scopus citations

Scanning electron microscopy of the lower urinary tract

Jacobs, J. B., Cohen, S. M. & Friedell, G. H., Jan 1 2017, Pathology of Bladder Cancer. CRC Press, p. 141-181 41 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations

The relevance of experimental carcinogenicity studies to human safety

Cohen, S. M., Apr 1 2017, In : Current Opinion in Toxicology. 3, p. 6-11 6 p.

Research output: Contribution to journalReview article

9 Scopus citations