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  • 2020
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  • Oksana Lockridge
2020

Characteristic fragment ions associated with dansyl cadaverine and biotin cadaverine adducts on glutamine

Biberoglu, K., Schopfer, L. M., Tacal, O. & Lockridge, O., Jul 1 2020, In : Analytical Biochemistry. 600, 113718.

Research output: Contribution to journalArticle

Open Access

Chlorpyrifos oxon-induced isopeptide bond formation in human butyrylcholinesterase

Biberoglu, K., Tacal, O., Schopfer, L. M. & Lockridge, O., Jan 25 2020, In : Molecules. 25, 3, 533.

Research output: Contribution to journalArticle

Open Access

Polyproline-rich peptides associated with Torpedo californica acetylcholinesterase tetramers

Toker, L., Silman, I., Zeev-Ben-Mordehai, T., Sussman, J. L., Schopfer, L. M. & Lockridge, O., Mar 1 2020, In : Chemico-Biological Interactions. 319, 109007.

Research output: Contribution to journalArticle

Open Access

Proline 285 is integral for the reactivation of organophosphate-inhibited human butyrylcholinesterase by 2-PAM*

diTargiani, R. C., Belinskaya, T., Tipparaju, P., Lockridge, O. & Saxena, A., Jun 1 2020, In : Chemico-Biological Interactions. 324, 109092.

Research output: Contribution to journalArticle

2019

Computer-designed active human butyrylcholinesterase double mutant with a new catalytic triad

Grigorenko, B. L., Novichkova, D. A., Lushchekina, S. V., Zueva, I. V., Schopfer, L. M., Nemukhin, A. V., Varfolomeev, S. D., Lockridge, O. & Masson, P., Jun 1 2019, In : Chemico-Biological Interactions. 306, p. 138-146 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Half-life of chlorpyrifos oxon and other organophosphorus esters in aqueous solution

Lockridge, O., Verdier, L. & Schopfer, L. M., Sep 25 2019, In : Chemico-Biological Interactions. 311, 108788.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
5 Scopus citations
7 Scopus citations
2018

Characterization of butyrylcholinesterase from porcine milk

Saxena, A., Belinskaya, T., Schopfer, L. M. & Lockridge, O., Aug 15 2018, In : Archives of Biochemistry and Biophysics. 652, p. 38-49 12 p.

Research output: Contribution to journalArticle

5 Scopus citations
6 Scopus citations

Cryo-EM structure of the native butyrylcholinesterase tetramer reveals a dimer of dimers stabilized by a superhelical assembly

Leung, M. R., van Bezouwen, L. S., Schopfer, L. M., Sussman, J. L., Silman, I., Lockridge, O. & Zeev-Ben-Mordehai, T., Dec 26 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 52, p. 13270-13275 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Delipidation of plasma has minimal effects on human butyrylcholinesterase

Onder, S., Tacal, O. & Lockridge, O., Feb 15 2018, In : Frontiers in Pharmacology. 9, FEB, 117.

Research output: Contribution to journalArticle

1 Scopus citations

Esterases

Lockridge, O., Quinn, D. M. & Radić, Z., Jan 1 2018, Biotransformation. Elsevier Inc., Vol. 10-15. p. 277-307 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
1 Scopus citations

Mass Spectral Detection of Diethoxyphospho-Tyrosine Adducts on Proteins from HEK293 Cells Using Monoclonal Antibody depY for Enrichment

Onder, S., Schopfer, L. M., Tacal, O., Blake, T. A., Johnson, R. C. & Lockridge, O., Jun 18 2018, In : Chemical Research in Toxicology. 31, 6, p. 520-530 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Optimization of cholinesterase-based catalytic bioscavengers against organophosphorus agents

Lushchekina, S. V., Schopfer, L. M., Grigorenko, B. L., Nemukhin, A. V., Varfolomeev, S. D., Lockridge, O. & Masson, P., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 211.

Research output: Contribution to journalArticle

12 Scopus citations

Purification of recombinant human butyrylcholinesterase on Hupresin®

Lockridge, O., David, E., Schopfer, L. M., Masson, P., Brazzolotto, X. & Nachon, F., Dec 1 2018, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1102-1103, p. 109-115 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Use of Hupresin to Capture Red Blood Cell Acetylcholinesterase for Detection of Soman Exposure

Onder, S., Schopfer, L. M., Cashman, J. R., Tacal, O., Johnson, R. C., Blake, T. A. & Lockridge, O., Jan 2 2018, In : Analytical chemistry. 90, 1, p. 974-979 6 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Characterization of butyrylcholinesterase in bovine serum

Dafferner, A. J., Lushchekina, S., Masson, P., Xiao, G., Schopfer, L. M. & Lockridge, O., Mar 25 2017, In : Chemico-Biological Interactions. 266, p. 17-27 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Hupresin retains binding capacity for butyrylcholinesterase and acetylcholinesterase after sanitation with sodium hydroxide

Onder, S., David, E., Tacal, O., Schopfer, L. M. & Lockridge, O., Oct 10 2017, In : Frontiers in Pharmacology. 8, OCT, 713.

Research output: Contribution to journalArticle

8 Scopus citations

Immunopurification of Acetylcholinesterase from Red Blood Cells for Detection of Nerve Agent Exposure

Dafferner, A. J., Schopfer, L. M., Xiao, G., Cashman, J. R., Yerramalla, U., Johnson, R. C., Blake, T. A. & Lockridge, O., Oct 16 2017, In : Chemical Research in Toxicology. 30, 10, p. 1897-1910 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Monoclonal Antibody That Recognizes Diethoxyphosphotyrosine-Modified Proteins and Peptides Independent of Surrounding Amino Acids

Onder, S., Dafferner, A. J., Schopfer, L. M., Xiao, G., Yerramalla, U., Tacal, O., Blake, T. A., Johnson, R. C. & Lockridge, O., Dec 18 2017, In : Chemical Research in Toxicology. 30, 12, p. 2218-2228 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

The C5 variant of the butyrylcholinesterase tetramer includes a noncovalently bound 60 kDa lamellipodin fragment

Schopfer, L. M., Delacour, H., Masson, P., Leroy, J., Krejci, E. & Lockridge, O., Jul 2017, In : Molecules. 22, 7, 1083.

Research output: Contribution to journalArticle

9 Scopus citations
2016
2 Scopus citations

Molecular polymorphism of human enzymes as the basis of individual sensitivity to drugs. Supercomputer-assisted modeling as a tool for analysis of structural changes and enzymatic activity of proteins

Varfolomeev, S. D., Lushchekina, S. V., Nemukhin, A. V., Kulakova, A. M., Kots, E. D., Makhaeva, G. F., Delacour, H., Lockridge, O. & Masson, P., Jun 1 2016, In : Russian Chemical Bulletin. 65, 6, p. 1592-1607 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma

Peng, H., Brimijoin, S., Hrabovska, A., Krejci, E., Blake, T. A., Johnson, R. C., Masson, P. & Lockridge, O., Jan 5 2016, In : Chemico-Biological Interactions. 243, p. 82-90 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
29 Scopus citations

Origin of polyproline-rich peptides in human butyrylcholinesterase tetramers

Peng, H., Schopfer, L. M. & Lockridge, O., Nov 25 2016, In : Chemico-Biological Interactions. 259, p. 63-69 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
8 Scopus citations