A (9;11)(q34;q13) translocation in a hibernoma

Kiran K. Turaga, Edibaldo Silva-Lopez, Warren G. Sanger, Marilu Nelson, William J. Hunter, Markku Miettinen, Zoran Gatalica

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


The diagnosis of hibernoma has historically been made by histopathologic examination and finding of characteristic brown fat cells with granular multivacuolated cytoplasm. The diagnosis of hibernoma may be complicated, however, because seemingly diagnostic cells could be mistakenly identified as lipoblasts, leading to the erroneous diagnosis of well-differentiated liposarcoma. Cytogenetic alterations in lipomatous tumors are well established and could be used for diagnostic purposes. Previous cytogenetic abnormalities reported in hibernomas have included alteration of 11q13 region. Here, we present a case of a hibernoma with a novel cytogenetic alteration involving a reciprocal translocation between 9q and 11q that was useful in establishing the final diagnosis.

Original languageEnglish (US)
Pages (from-to)163-166
Number of pages4
JournalCancer genetics and cytogenetics
Issue number2
StatePublished - Oct 15 2006

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research


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