TY - GEN
T1 - A biological circuit design for modulated parity-check encoding in molecular communication
AU - Marcone, Alessio
AU - Pierobon, Massimiliano
AU - Magarini, Maurizio
N1 - Funding Information:
ACKNOWLEDGMENT This work was supported by the US National Science Foundation (NSF) through grant MCB-1449014, and the NSF EPSCoR First Award EPS-1004094. REFERENCES
Publisher Copyright:
© 2017 IEEE.
PY - 2017/7/28
Y1 - 2017/7/28
N2 - Regarded as one of the future enabling technologies of the Internet of Things at the biological and nanoscale domains, Molecular Communication (MC) promises to enable applications in healthcare, environmental protection, and bioremediation, amongst others. Since MC is directly inspired by communication processes in biological cells, the engineering of biological circuits through cells' genetic code manipulation, which enables access to the cells' information processing abilities, is a candidate technology for the future realization of MC components. In this paper, inspired by previous research on channel coding schemes for MC and biological circuits for cell communications, a joint encoder and modulator design is proposed for the transmission of cellular information through signaling molecules. In particular, the information encoding and modulation are based on a binary parity check scheme, and they are implemented by interconnecting biological circuit components based on gene expression and mass action reactions. Each component is mathematically modeled and tuned according to the desired output. The implementation of the biological circuit in a simulation environment is then presented along with the corresponding numerical results, which validate the proposed design by showing agreement with an ideal encoding and modulator scheme.
AB - Regarded as one of the future enabling technologies of the Internet of Things at the biological and nanoscale domains, Molecular Communication (MC) promises to enable applications in healthcare, environmental protection, and bioremediation, amongst others. Since MC is directly inspired by communication processes in biological cells, the engineering of biological circuits through cells' genetic code manipulation, which enables access to the cells' information processing abilities, is a candidate technology for the future realization of MC components. In this paper, inspired by previous research on channel coding schemes for MC and biological circuits for cell communications, a joint encoder and modulator design is proposed for the transmission of cellular information through signaling molecules. In particular, the information encoding and modulation are based on a binary parity check scheme, and they are implemented by interconnecting biological circuit components based on gene expression and mass action reactions. Each component is mathematically modeled and tuned according to the desired output. The implementation of the biological circuit in a simulation environment is then presented along with the corresponding numerical results, which validate the proposed design by showing agreement with an ideal encoding and modulator scheme.
KW - Hill function
KW - Molecular communication
KW - biochemical simulation
KW - biological circuit
KW - chemical reaction modeling
KW - parity-check encoding
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U2 - 10.1109/ICC.2017.7997032
DO - 10.1109/ICC.2017.7997032
M3 - Conference contribution
AN - SCOPUS:85028297214
T3 - IEEE International Conference on Communications
BT - 2017 IEEE International Conference on Communications, ICC 2017
A2 - Debbah, Merouane
A2 - Gesbert, David
A2 - Mellouk, Abdelhamid
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2017 IEEE International Conference on Communications, ICC 2017
Y2 - 21 May 2017 through 25 May 2017
ER -