A microbially generated metabolite, PAGIn, is associated with cardiovascular disease and death in humans. Studies in animal models provide insights into PAGIn metabolism as well as its effects in driving platelet invasiveness and thrombosis through adrenergic receptors.
- adrenergic receptors
- cardiovascular disease
- gut microbe
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)