Abstract
An 83‐year‐old woman who had a 5‐year history of agnogenic myeloid metaplasia and a previous normal marrow cell karyotype presented with acute myelogenous leukemia (AML) associated with the development of trisomy 11 in 100% of cultured marrow cells. Isolated trisomy 11 in marrow cells has been reported previously in five cases of AML, suggesting that trisomy 11 is a nonrandom chromosomal aberration associated with AML.
Original language | English (US) |
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Pages (from-to) | 285-288 |
Number of pages | 4 |
Journal | American Journal of Hematology |
Volume | 19 |
Issue number | 3 |
DOIs | |
State | Published - Jul 1985 |
Externally published | Yes |
Keywords
- acute myelogenous leukemia
- agnogenic myeloid metaplasia
- trisomy 11
ASJC Scopus subject areas
- Hematology