A Checklist-Based intervention to improve surgical outcomes in Michigan evaluation of the keystone surgery program

Bradley N. Reames, Robert W. Krell, Darrell A. Campbell, Justin B. Dimick

Research output: Contribution to journalArticlepeer-review

62 Scopus citations


Importance: Previous studies of checklist-based quality improvement interventions have reported mixed results. Objective: To evaluate whether implementation of a checklist-based quality improvement intervention-Keystone Surgery-was associated with improved outcomes in patients in a large statewide population undergoing general surgery. Design, Setting, and Exposures: A retrospective longitudinal study examined surgical outcomes in 64 891 Michigan patients in 29 hospitals using Michigan Surgical Quality Collaborative clinical registry data from 2006 through 2010. Multivariable logistic regression and difference-in-differences analytic approaches were used to evaluate whether Keystone Surgery program implementation was associated with improved surgical outcomes following general surgery procedures, apart from existing temporal trends toward improved outcomes during the study period. Main Outcomes And Measures: Risk-adjusted rates of superficial surgical site infection, wound complication, any complication, and 30-day mortality. Results: Implementation of Keystone Surgery in 14 participating centers was not associated with improvements in surgical outcomes during the study period. Adjusted rates of superficial surgical site infection (3.2%vs 3.2%, P = .91), wound complication (5.9%vs 6.5%, P = .30), any complication (12.4%vs 13.2%, P = .26), and 30-day mortality (2.1% vs 1.9%, P = .32) at participating hospitals were similar before and after implementation. Difference-in-differences analysis accounting for trends in 15 nonparticipating centers and sensitivity analysis excluding patients receiving surgery in the first 6 or 12 months after program implementation yielded similar results.

Original languageEnglish (US)
Pages (from-to)208-215
Number of pages8
JournalJAMA Surgery
Issue number3
StatePublished - Mar 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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